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SBGrid Consortium
The SBGrid Consortium is a research computing group financially supported by participating research laboratories and operated out of Harvard Medical School. SBGrid provides the global structural biology community with support for research computing. Members of the SBGrid Consortium fund SBGrid’s ongoing operations through an annual membership fee. The resulting organization is a user-supported and user-directed community resource. SBGrid’s primary service is the collection, deployment and maintenance of a comprehensive set of software and computational tools that are useful in structural biology research. As of 2015, SBGrid curates a collection of 300 structural biology applications for installation on computers in SBGrid laboratories around the world. SBGrid also develops a specialized research computing infrastructure for structural biologists in the Boston area. Background SBGrid was first created by Piotr Sliz as an in-house effort to support and maintain a few dozen X- ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harvard Medical School
Harvard Medical School (HMS) is the medical school of Harvard University and is located in the Longwood Medical and Academic Area, Longwood Medical Area in Boston, Massachusetts. Founded in 1782, HMS is the third oldest medical school in the United States. It provides patient care, medical education, and research training through its 15 clinical affiliates and research institutes, including Massachusetts General Hospital (MGH), Boston Children's Hospital, Dana–Farber Cancer Institute, Brigham and Women's Hospital, Beth Israel Deaconess Medical Center, Mount Auburn Hospital, McLean Hospital, Cambridge Health Alliance, The Baker Center for Children and Families, Spaulding Rehabilitation Hospital, and others. Harvard Medical School also partners with newer entities such as Harvard Catalyst, Broad Institute , Broad Institute of MIT and Harvard, Harvard Stem Cell Institute, the Center for Primary Care, and Wyss Institute for Biologically Inspired Engineering. History Harvard ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Structural Biology
Structural biology deals with structural analysis of living material (formed, composed of, and/or maintained and refined by living cells) at every level of organization. Early structural biologists throughout the 19th and early 20th centuries were primarily only able to study structures to the limit of the naked eye's visual acuity and through magnifying glasses and light microscopes. In the 20th century, a variety of experimental techniques were developed to examine the 3D structures of biological molecules. The most prominent techniques are X-ray crystallography, nuclear magnetic resonance, and Electron microscope, electron microscopy. Through the discovery of X-ray, X-rays and its applications to protein crystals, structural biology was revolutionized, as now scientists could obtain the three-dimensional structures of biological molecules in atomic detail. Likewise, Nuclear magnetic resonance spectroscopy, NMR spectroscopy allowed information about protein structure and dynamic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Boston
Boston is the capital and most populous city in the Commonwealth (U.S. state), Commonwealth of Massachusetts in the United States. The city serves as the cultural and Financial centre, financial center of New England, a region of the Northeastern United States. It has an area of and a population of 675,647 as of the 2020 United States census, 2020 census, making it the third-largest city in the Northeastern United States after New York City and Philadelphia. The larger Greater Boston metropolitan statistical area has a population of 4.9 million as of 2023, making it the largest metropolitan area in New England and the Metropolitan statistical area, eleventh-largest in the United States. Boston was founded on Shawmut Peninsula in 1630 by English Puritans, Puritan settlers, who named the city after the market town of Boston, Lincolnshire in England. During the American Revolution and American Revolutionary War, Revolutionary War, Boston was home to several seminal events, incl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stephen C
Stephen or Steven is an English first name. It is particularly significant to Christians, as it belonged to Saint Stephen ( ), an early disciple and deacon who, according to the Book of Acts, was stoned to death; he is widely regarded as the first martyr (or " protomartyr") of the Christian Church. The name, in both the forms Stephen and Steven, is often shortened to Steve or Stevie. In English, the female version of the name is Stephanie. Many surnames are derived from the first name, including Stephens, Stevens, Stephenson, and Stevenson, all of which mean "Stephen's (son)". In modern times the name has sometimes been given with intentionally non-standard spelling, such as Stevan or Stevon. A common variant of the name used in English is Stephan ( ); related names that have found some currency or significance in English include Stefan (pronounced or in English), Esteban (often pronounced ), and the Shakespearean Stephano ( ). Origins The name "Stephen" ( ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Don Craig Wiley
Don Craig Wiley (October 21, 1944 – November 15, 2001) was an American structural biologist. Education Wiley received his doctoral degree in biophysics in 1971 from Harvard University, where he worked under the direction of the subsequent 1976 chemistry Nobel Prize winner William N. Lipscomb, Jr. There, Wiley did early work on the structure of aspartate carbamoyltransferase, the largest molecular structure determined at that time. Noteworthy in this effort was that Wiley managed to grow crystals of aspartate carbamoyltransferase suitable for obtaining its X-ray structure, a particularly difficult task in the case of this molecular complex. Career and research Wiley was world-renowned for finding new ways to help the human immune system battle such viral scourges as smallpox, influenza, HIV/AIDS and herpes simplex. Famous quote: "I'm sorry, but I just don't understand anything in biology unless I know what it looks like." Awards and honors In 1990, he was awarded the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harvard University
Harvard University is a Private university, private Ivy League research university in Cambridge, Massachusetts, United States. Founded in 1636 and named for its first benefactor, the History of the Puritans in North America, Puritan clergyman John Harvard (clergyman), John Harvard, it is the oldest institution of higher learning in the United States. Its influence, wealth, and rankings have made it one of the most prestigious universities in the world. Harvard was founded and authorized by the Massachusetts General Court, the governing legislature of Colonial history of the United States, colonial-era Massachusetts Bay Colony. While never formally affiliated with any Religious denomination, denomination, Harvard trained Congregationalism in the United States, Congregational clergy until its curriculum and student body were gradually secularized in the 18th century. By the 19th century, Harvard emerged as the most prominent academic and cultural institution among the Boston B ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Boston Children’s Hospital
Boston Children's Hospital (formerly known as Children's Hospital Boston until 2013) is the main pediatric training and research hospital of Harvard Medical School, Harvard University. It is a nationally ranked, freestanding acute care Pediatrics, children's hospital located at the centre of Longwood Medical and Academic Area, Harvard Longwood Medical and Academic Area in Boston, Massachusetts. The hospital is home to the world's largest pediatric research enterprise, and it is the leading recipient of pediatric research funding from the National Institutes of Health, National Institutes of Health (NIH). It provides comprehensive pediatric specialties and subspecialties to infants, children, teens, and young adults aged 0–21 throughout Massachusetts, the United States, and the world. The hospital also sometimes treats adults that require pediatric care. The hospital uses the Brigham and Women's Hospital's rooftop helipad and is an American College of Surgeons, ACS verified Level ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
