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RpYN06
Bat coronavirus RpYN06 is a SARS-like betacoronavirus that infects the horseshoe bat '' Rhinolophus pusillus'', it is a close relative of SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) is a strain of coronavirus that causes COVID-19 (coronavirus disease 2019), the respiratory illness responsible for the ongoing COVID-19 pandemic. The virus previously had a ... with a 94.48% sequence identity. Phylogenetics References {{Coronaviridae Bat virome Coronaviridae Infraspecific virus taxa ...
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Betacoronavirus
''Betacoronavirus'' (β-CoVs or Beta-CoVs) is one of four genera ('' Alpha''-, ''Beta-'', '' Gamma-'', and '' Delta-'') of coronaviruses. Member viruses are enveloped, positive-strand RNA viruses that infect mammals (of which humans are part). The natural reservoir for betacoronaviruses are bats and rodents. Rodents are the reservoir for the subgenus ''Embecovirus'', while bats are the reservoir for the other subgenera. The coronavirus genera are each composed of varying viral lineages with the betacoronavirus genus containing four such lineages: A, B, C, D. In older literature, this genus is also known as "group 2 coronaviruses". The genus is in the subfamily ''Orthocoronavirinae'' in the family ''Coronaviridae'', of the order '' Nidovirales''. The betacoronaviruses of the greatest clinical importance concerning humans are OC43 and HKU1 (which can cause the common cold) of lineage A, SARS-CoV and SARS-CoV-2 (which has caused the disease COVID-19) of lineage B, and MER ...
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Least Horseshoe Bat
The least horseshoe bat (''Rhinolophus pusillus'') is a species of bat in the family Rhinolophidae. It is found in Cambodia, China, India, Indonesia, Laos, Malaysia, Myanmar, Nepal, Thailand and Vietnam. It is a food source of the parasite Sinospelaeobdella, a jawed land leech. See also * * * List of mammals in Hong Kong This is a list of the mammal species recorded in Hong Kong. There are 68 mammal species in Hong Kong. The following tags are used to highlight each species' conservation status as assessed by the International Union for Conservation of Nature: ... References Rhinolophidae Bats of Asia Bats of Southeast Asia Bats of Indonesia Bats of Malaysia Mammals of Myanmar Mammals of Cambodia Bats of China Fauna of Hong Kong Mammals of India Mammals of Japan Mammals of Laos Mammals of Nepal Mammals of the Philippines Mammals of Singapore Mammals of Taiwan Mammals of Thailand Mammals of Vietnam Mammals described in 1834 Taxonomy articles c ...
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Severe Acute Respiratory Syndrome Coronavirus 2
Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) is a strain of coronavirus that causes COVID-19 (coronavirus disease 2019), the respiratory illness responsible for the ongoing COVID-19 pandemic. The virus previously had a provisional name, 2019 novel coronavirus (2019-nCoV), and has also been called the human coronavirus 2019 (HCoV-19 or hCoV-19). First identified in the city of Wuhan, Hubei, China, the World Health Organization declared the outbreak a public health emergency of international concern on January 30, 2020, and a pandemic on March 11, 2020. SARS‑CoV‑2 is a positive-sense single-stranded RNA virus that is contagious in humans. SARS‑CoV‑2 is a virus of the species '' severe acute respiratory syndrome–related coronavirus'' (SARSr-CoV), related to the SARS-CoV-1 virus that caused the 2002–2004 SARS outbreak. Despite its close relation to SARS-CoV-1, its closest known relatives, with which it forms a sister group, are the derived ...
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Sequence Alignment
In bioinformatics, a sequence alignment is a way of arranging the sequences of DNA, RNA, or protein to identify regions of similarity that may be a consequence of functional, structural, or evolutionary relationships between the sequences. Aligned sequences of nucleotide or amino acid residues are typically represented as rows within a matrix. Gaps are inserted between the residues so that identical or similar characters are aligned in successive columns. Sequence alignments are also used for non-biological sequences, such as calculating the distance cost between strings in a natural language or in financial data. Interpretation If two sequences in an alignment share a common ancestor, mismatches can be interpreted as point mutations and gaps as indels (that is, insertion or deletion mutations) introduced in one or both lineages in the time since they diverged from one another. In sequence alignments of proteins, the degree of similarity between amino acids occupying a pa ...
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Bat Virome
The bat virome is the group of viruses associated with bats. Bats host a diverse array of viruses, including all seven types described by the Baltimore classification system: (I) double-stranded DNA viruses; (II) single-stranded DNA viruses; (III) double-stranded RNA viruses; (IV) positive-sense single-stranded RNA viruses; (V) negative-sense single-stranded RNA viruses; (VI) positive-sense single-stranded RNA viruses that replicate through a DNA intermediate; and (VII) double-stranded DNA viruses that replicate through a single-stranded RNA intermediate. The greatest share of bat-associated viruses identified as of 2020 are of type IV, in the family '' Coronaviridae''. Bats harbor several viruses that are zoonotic, or capable of infecting humans, and some bat-borne viruses are considered important emerging viruses. These zoonotic viruses include the rabies virus, SARS-CoV, MERS-CoV, Marburg virus, Nipah virus, and Hendra virus. While research clearly indicates tha ...
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Coronaviridae
''Coronaviridae'' is a family of enveloped, positive-strand RNA viruses which infect amphibians, birds, and mammals. The group includes the subfamilies '' Letovirinae'' and ''Orthocoronavirinae;'' the members of the latter are known as coronaviruses. The viral genome is 26–32 kilobases in length. The particles are typically decorated with large (~20 nm), club- or petal-shaped surface projections (the " peplomers" or "spikes"), which in electron micrographs of spherical particles create an image reminiscent of the solar corona. Virology The 5' and 3' ends of the genome have a cap and poly(A) tract, respectively. The viral envelope, obtained by budding through membranes of the endoplasmic reticulum (ER) or Golgi apparatus, invariably contains two virus-specified glycoprotein species, known as the spike (S) and membrane (M) proteins. The spike protein makes up the large surface projections (sometimes known as peplomers), while the membrane protein is a triple-spanni ...
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