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Rosin (chemical)
Rosin is a glycoside ester of cinnamyl alcohol and a constituent of ''Rhodiola rosea''. Related compounds The three cinnamyl alcohol-vicianosides of Rhodiola rosea, commonly referred to as "rosavins," are rosin, and the structurally related disaccharide rosavin, which is the arabinose ester of rosin, and rosarin, the arabinofuranose ester of rosin. Salidroside, common in Rhodiola spp. and occurring in Rhodiola rosea is not a cinnamyl alcohol glycoside, but a glycoside of tyrosol Tyrosol is an organic compound with the formula . Classified as a phenylethanoid, a derivative of phenethyl alcohol, it is found in a variety of natural sources. The compound is colorless solid. The principal source in the human diet is olive oi .... Sources The cinnamyl alcohol glycosides rosin, rosavin and rosarin occur in the context of rhodiola species, only in Rhodiola rosea. References Crassulaceae Neuroprotective agents Phenylpropanoid glycosides {{organic-chem-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cinnamyl Alcohol
Cinnamyl alcohol or styron is an organic compound that is found in esterified form in storax, Balsam of Peru, and cinnamon leaves. It forms a white crystalline solid when pure, or a yellow oil when even slightly impure. It can be produced by the hydrolysis of storax. Cinnamyl alcohol occurs naturally only in small quantities, so its industrial demand is usually fulfilled by chemical synthesis starting from cinnamaldehyde. Properties The compound is a solid at room temperature, forming colorless crystals that melt upon gentle heating. As is typical of most higher-molecular weight alcohols, it is sparingly soluble in water at room temperature, but highly soluble in most common organic solvents. Uses Cinnamyl alcohol has a distinctive odor described as "sweet, balsam, hyacinth, spicy, green, powdery, cinnamic" and is used in perfumery and as a deodorant. Cinnamyl alcohol is the starting material used in the synthesis of reboxetine. Safety Cinnamyl alcohol has been found to have ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rhodiola Rosea
''Rhodiola rosea'' (commonly golden root, rose root, roseroot, Aaron's rod, Arctic root, king's crown, ''lignum rhodium'', orpin rose) is a perennial plant, perennial flowering plant in the family Crassulaceae. It grows naturally in wild Arctic regions of Europe (including Britain), Asia, and North America ( N.B., Nfld. and Labrador, N.S., QC.; Alaska, Maine, N.Y., N.C., Pa., Vt), and can be propagated as a groundcover. Although ''Rhodiola rosea'' has been used in traditional medicine, there is no high-quality evidence-based medicine, clinical evidence of its effectiveness to treat any disease. The United States Food and Drug Administration has FDA warning letter, issued several warnings to manufacturers of ''R. rosea'' dietary supplements for making false health claims about its safety and efficacy. The plant is threatened in many countries due to rapidly growing demand. Supply comes mostly from wild harvesting on an industrial scale, and a combination of growing scarcity and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rosavin
Rosavin is a chemical compound with the molecular formula . It is a diglycoside of cinnamyl alcohol. Rosavin and related glycosides of cinnamyl alcohol, including rosin and rosarin, are key chemical constituents of ''Rhodiola rosea'' L., (''R. rosea''). ''R. rosea'' is an important medicinal plant commonly used throughout Europe, Asia, and North America, that has been recognized as a botanical adaptogen by the European Medicines Agency. Rosavin production is specific to ''R. rosea'' and ''R. sachalinenis'', and the biosynthesis of these glycosides occurs spontaneously in ''Rhodiola'' roots and rhizomes. The production of rosavins increases in plants as they get older, and the amount of the cinnamyl alcohol glycosides depends on the place of origin of the plant. Biosynthesis Cinnamyl alcohol glycosides are products of phenylpropanoid metabolism, derived from phenylalanine, which is produced from the shikimic-chorismic acid pathway. Shikimic acid is made from the precursor compo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Arabinose
Arabinose is an aldopentose – a monosaccharide containing five carbon atoms, and including an aldehyde (CHO) functional group. Properties For biosynthetic reasons, most saccharides are almost always more abundant in nature as the "D"-form, or structurally analogous to D-glyceraldehyde.The D/L nomenclature does not refer to the molecule's optical rotation properties but to its structural analogy to glyceraldehyde. However, L-arabinose is in fact more common than D-arabinose in nature and is found in nature as a component of biopolymers such as hemicellulose and pectin. The L-arabinose operon, also known as the araBAD operon, has been the subject of much biomolecular research. The operon directs the catabolism of arabinose in ''E. coli'', and it is dynamically activated in the presence of arabinose and the absence of glucose. A classic method for the organic synthesis of arabinose from glucose is the Wohl degradation. : Etymology Arabinose gets its name from gum arabic, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rosarin
Rosarin is a cinnamyl alcohol glycoside isolated from ''Rhodiola rosea''. See also * Rosavin * Rosin Rosin (), also known as colophony or Greek pitch (), is a resinous material obtained from pine trees and other plants, mostly conifers. The primary components of rosin are diterpenoids, i.e., C20 carboxylic acids. Rosin consists mainly of r ... References Phenylpropanoid glycosides {{Carbohydrate-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Salidroside
Salidroside (rhodioloside) is a glucoside of tyrosol found in the plant ''Rhodiola rosea''. It has been studied, along with rosavin, as one of the potential compounds responsible for the putative antidepressant and anxiolytic actions of this plant. Salidroside may be more active than rosavin, even though many commercially marketed ''Rhodiola rosea'' extracts are standardized for rosavin content rather than salidroside. Bioactivities Salidroside was shown to improve glucose homeostasis and alleviate diabetic retinopathy in obese mice. The antioxidant, anti-inflammatory and neuroprotective effects of salidroside have also been reported. Biosynthesis The salidroside biosynthetic pathway in ''Rhodiola rosea'' was described in 2018. Rhodiola contains a pyridoxal phosphate-dependent 4-hydroxyphenylacetaldehyde (4-HPAA) synthase that converts tyrosine to 4-HPAA, which is further reduced to tyrosol Tyrosol is an organic compound with the formula . Classified as a phenylethanoid, a der ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Glycoside
In chemistry, a glycoside is a molecule in which a sugar is bound to another functional group via a glycosidic bond. Glycosides play numerous important roles in living organisms. Many plants store chemicals in the form of inactive glycosides. These can be activated by enzymatic, enzyme hydrolysis, which causes the sugar part to be broken off, making the chemical available for use. Many such plant glycosides are used as medications. Several species of ''Heliconius'' butterfly are capable of incorporating these plant compounds as a form of chemical defense against predators. In animals and humans, poisons are often bound to sugar molecules as part of their elimination from the body. In formal terms, a glycoside is any molecule in which a sugar group is bonded through its anomeric carbon to another group via a glycosidic bond. Glycosides can be linked by an O- (an ''O-glycoside''), N- (a ''glycosylamine''), S-(a ''thioglycoside''), or C- (a ''C-glycoside'') glycosidic bond. Accord ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tyrosol
Tyrosol is an organic compound with the formula . Classified as a phenylethanoid, a derivative of phenethyl alcohol, it is found in a variety of natural sources. The compound is colorless solid. The principal source in the human diet is olive oil. Research As an antioxidant, tyrosol may protect cells against injury due to oxidation ''in vitro''. Although it is not as potent as other antioxidants present in olive oil (e.g., hydroxytyrosol), its higher concentration and good bioavailability indicate that it may have an important overall effect. Tyrosol may also be cardioprotective. Tyrosol-treated animals showed significant increase in the phosphorylation of Akt, eNOS, and FOXO3a. In addition, tyrosol also induced the expression of the protein SIRT1 in the heart after myocardial infarction (MI) in a rat MI model. Tyrosol forms esters with a variety of organic acids. For example, oleocanthal is the elenolic acid ester of tyrosol. See also * Tyrosinol, * Hydroxytyrosol ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Oulu
The University of Oulu () is one of the largest universities in Finland, located in the city of Oulu. It was founded on July 8, 1958. The university has around 14,200 students and 3,800 staff. 21 International Master's Programmes are offered at the university. The university is often ranked as one of the best universities in Finland and in the top 400 worldwide. History * 1919 Oulu College Association was founded to manage the establishment of a university in the town * 1958 Oulu University Act * 1959 Activities begin. Faculty of Philosophy (programs in biology and mathematics), Faculty of Technology (architecture, civil and industrial engineering) and Oulu Teaching School * 1960 Faculty of Medicine * 1965 Teaching begins in humanities * 1965 Departments of Electrical Engineering and Machine Engineering added to the Faculty of Technology * 1972 The Faculty of Humanities and the Faculty of Natural Sciences founded with the division of the Faculty of Philosophy * 1974 Facul ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Crassulaceae
The Crassulaceae (, from Latin ''crassus'', thick), also known as the crassulas, the stonecrops or the orpine family, are a diverse Family (biology), family of dicotyledon angiosperms primarily characterized by succulent leaves and a form of photosynthesis known as crassulacean acid metabolism (CAM), in which plants photosynthesize in the daytime and exchange gases during the cooler temperatures of the night. The blossoms of crassulas generally have five floral parts. Crassulaceae are usually herbaceous, though there are some subshrubs, and relatively few trees or aquatic plants. The Crassulaceae is a medium-sized, monophyletic family in the core eudicots clade, along with the order Saxifragales, whose diversity has made infrafamilial classification very difficult. The family includes approximately 1,400 species and 34–35 genera—depending on the circumscription of the genus ''Sedum''—distributed over three subfamilies. Members of the Crassulaceae are found worldwide, though ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neuroprotective Agents
Neuroprotection refers to the relative preservation of neuronal structure and/or function. In the case of an ongoing insult (a neurodegenerative insult) the relative preservation of neuronal integrity implies a reduction in the rate of neuronal loss over time, which can be expressed as a differential equation. Mechanisms in neurodegeneration, and associated treatments It is a widely explored treatment option for many central nervous system disorders including neurodegenerative diseases, stroke, traumatic brain injury, spinal cord injury, and acute management of neurotoxin consumption (i.e. methamphetamine overdoses). Neuroprotection aims to prevent or slow disease progression and secondary injuries by halting or at least slowing the loss of neurons. Despite differences in symptoms or injuries associated with CNS disorders, many of the mechanisms behind neurodegeneration are the same. Common mechanisms of neuronal injury include decreased delivery of oxygen and glucose to the bra ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
