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Tyrosol
Tyrosol is an organic compound with the formula . Classified as a phenylethanoid, a derivative of phenethyl alcohol, it is found in a variety of natural sources. The compound is colorless solid. The principal source in the human diet is olive oil. Research As an antioxidant, tyrosol may protect cells against injury due to oxidation ''in vitro''. Although it is not as potent as other antioxidants present in olive oil (e.g., hydroxytyrosol), its higher concentration and good bioavailability indicate that it may have an important overall effect. Tyrosol may also be cardioprotective. Tyrosol-treated animals showed significant increase in the phosphorylation of Akt, eNOS, and FOXO3a. In addition, tyrosol also induced the expression of the protein SIRT1 in the heart after myocardial infarction (MI) in a rat MI model. Tyrosol forms esters with a variety of organic acids. For example, oleocanthal is the elenolic acid ester of tyrosol. See also * Tyrosinol, * Hydroxytyrosol ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phenylethanoid
Phenylethanoids are a type of phenolic compounds characterized by a phenethyl alcohol structure. Tyrosol and hydroxytyrosol are examples of such compounds. Glycosides The red deadnettle (''Lamium purpureum'') contains phenylethanoid glycosides named lamiuside A, lamiusides A, lamiuside B, B, lamiuside C, C, lamiuside D, D and lamiuside E, E. The aerial parts of ''Stachys officinalis'' contain phenylethanoid glycosides, (betonyoside A, betonyosides A, betonyoside B, B, betonyoside C, C, betonyoside D, D, betonyoside E, E and betonyoside F, F). Chemical investigation of methanol extracts from ''Pithecoctenium crucigerum'' (Bignoniaceae) showed the presence of five phenylethanoid glycosides (verbascoside, isoverbascoside, forsythoside B, jionoside D and leucosceptoside B), these all active against DPPH. Verbascoside and echinacoside are phenylethanoid and phenylpropanoid hybrids forming ester bonds with sugars. References {{aromatic-stub Phenylethanoids, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hydroxytyrosol
Hydroxytyrosol is an organic compound with the formula . It is a phenylethanoid, i.e. a relative of phenethyl alcohol. Its derivatives are found in a variety of natural sources, notably olive oils and wines. Hydroxytyrosol is a colorless solid, although samples often turn beige during storage. It is a derivative, formally speaking, of catechol. Hydroxytyrosol and its derivatives occur in olives and in wines. Occurrence Olives left, ester.html" ;"title="Oleuropein, bitter compound, an ester">Oleuropein, bitter compound, an ester of hydroxytyrosol found in green olive skin The olives, leaves, and olive pulp contain large amounts of hydroxytyrosol derivative oleuropein, more so than olive oil. Unprocessed, green (unripe) olives contain between 4.3 and 116 mg of hydroxytyrosol per 100 g of olives, while unprocessed, black (ripe) olives contain up to 413.3 mg per 100 g. The ripening of an olive substantially increases the amount of hydroxytyrosol. Processed olives, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Salidroside
Salidroside (rhodioloside) is a glucoside of tyrosol found in the plant ''Rhodiola rosea''. It has been studied, along with rosavin, as one of the potential compounds responsible for the putative antidepressant and anxiolytic actions of this plant. Salidroside may be more active than rosavin, even though many commercially marketed ''Rhodiola rosea'' extracts are standardized for rosavin content rather than salidroside. Bioactivities Salidroside was shown to improve glucose homeostasis and alleviate diabetic retinopathy in obese mice. The antioxidant, anti-inflammatory and neuroprotective effects of salidroside have also been reported. Biosynthesis The salidroside biosynthetic pathway in ''Rhodiola rosea'' was described in 2018. Rhodiola contains a pyridoxal phosphate-dependent 4-hydroxyphenylacetaldehyde (4-HPAA) synthase that converts tyrosine to 4-HPAA, which is further reduced to tyrosol Tyrosol is an organic compound with the formula . Classified as a phenylethanoid, a der ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tyrosinol
Tyrosinol is an organic compound with the formula . A colorless or white solid, it is produced by the reduction of the amino acid tyrosine with borane dimethylsulfide. The compound, which is chiral, is an example of a 1,2-ethanolamine as well as a phenethylamine. Related compounds * Tyrosol Tyrosol is an organic compound with the formula . Classified as a phenylethanoid, a derivative of phenethyl alcohol, it is found in a variety of natural sources. The compound is colorless solid. The principal source in the human diet is olive oi ..., {{chem2, HOC6H4CH2CH2OH References Primary alcohols Amines ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Organic Compound
Some chemical authorities define an organic compound as a chemical compound that contains a carbon–hydrogen or carbon–carbon bond; others consider an organic compound to be any chemical compound that contains carbon. For example, carbon-containing compounds such as alkanes (e.g. methane ) and its derivatives are universally considered organic, but many others are sometimes considered inorganic, such as certain compounds of carbon with nitrogen and oxygen (e.g. cyanide ion , hydrogen cyanide , chloroformic acid , carbon dioxide , and carbonate ion ). Due to carbon's ability to catenate (form chains with other carbon atoms), millions of organic compounds are known. The study of the properties, reactions, and syntheses of organic compounds comprise the discipline known as organic chemistry. For historical reasons, a few classes of carbon-containing compounds (e.g., carbonate salts and cyanide salts), along with a few other exceptions (e.g., carbon dioxide, and even ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Myocardial Infarction
A myocardial infarction (MI), commonly known as a heart attack, occurs when Ischemia, blood flow decreases or stops in one of the coronary arteries of the heart, causing infarction (tissue death) to the heart muscle. The most common symptom is retrosternal Angina, chest pain or discomfort that classically radiates to the left shoulder, arm, or jaw. The pain may occasionally feel like heartburn. This is the dangerous type of acute coronary syndrome. Other symptoms may include shortness of breath, nausea, presyncope, feeling faint, a diaphoresis, cold sweat, Fatigue, feeling tired, and decreased level of consciousness. About 30% of people have atypical symptoms. Women more often present without chest pain and instead have neck pain, arm pain or feel tired. Among those over 75 years old, about 5% have had an MI with little or no history of symptoms. An MI may cause heart failure, an Cardiac arrhythmia, irregular heartbeat, cardiogenic shock or cardiac arrest. Most MIs occur d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phenol Antioxidants
Phenol (also known as carbolic acid, phenolic acid, or benzenol) is an aromatic organic compound with the molecular formula . It is a white crystalline solid that is volatile and can catch fire. The molecule consists of a phenyl group () bonded to a hydroxy group (). Mildly acidic, it requires careful handling because it can cause chemical burns. It is acutely toxic and is considered a health hazard. Phenol was first extracted from coal tar, but today is produced on a large scale (about 7 million tonnes a year) from petroleum-derived feedstocks. It is an important industrial commodity as a precursor to many materials and useful compounds, and is a liquid when manufactured. It is primarily used to synthesize plastics and related materials. Phenol and its chemical derivatives are essential for production of polycarbonates, epoxies, explosives such as picric acid, Bakelite, nylon, detergents, herbicides such as phenoxy herbicides, and numerous pharmaceutical drugs. Propertie ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Elenolic Acid
Elenolic acid is a component of olive oil and olive leaf extract. It can be considered as a marker for maturation of olives. It is a subunit of oleuropein, a bitter chemical compound found in olives and the leaves of the olive tree, alongside closely related compounds such as 10-hydroxyoleuropein, ligstroside and 10-hydroxyligstroside, are tyrosol ester In chemistry, an ester is a compound derived from an acid (either organic or inorganic) in which the hydrogen atom (H) of at least one acidic hydroxyl group () of that acid is replaced by an organyl group (R). These compounds contain a distin ...s of elenolic acid. References {{heterocyclic-stub Carboxylic acids Aldehydes Dihydropyrans Methyl esters ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oleocanthal
Oleocanthal is a phenylethanoid, or a type of natural phenolic compound found in extra-virgin olive oil. It appears to be responsible for the burning sensation that occurs in the back of the throat when consuming such oil. Oleocanthal is a tyrosol ester and its chemical structure is related to oleuropein, also found in olive oil. Potential biological effects Anti-inflammatory Oleocanthal has been found to have anti-inflammatory and antioxidant properties ''in vitro''. Similar to the classical non-steroidal anti-inflammatory drug ibuprofen, it is a non-selective inhibitor of cyclooxygenase (COX). 50 g (more than three and a half tablespoons) of a typical extra virgin olive oil per day contains an amount of oleocanthal with similar ''in vitro'' anti-inflammatory effect as 1/10 of the adult ibuprofen dose. It is therefore suggested that long-term consumption of small quantities may be responsible in part for the low incidence of heart disease and Alzheimer's disease associ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Journal Of Agricultural And Food Chemistry
The ''Journal of Agricultural and Food Chemistry'' is a weekly peer-reviewed scientific journal established in 1953 by the American Chemical Society. Since 2015, Thomas Hofmann (Technical University of Munich) has been the editor-in-chief. The journal covers research dealing with the chemistry and biochemistry of agriculture and food including work with chemistry and/or biochemistry as a major component combined with biological/sensory/nutritional/toxicological evaluation related to agriculture and/or food. Abstracting and indexing The journal is abstracted and indexed in Chemical Abstracts Service, Scopus, ProQuest, PubMed, CABI, and the Science Citation Index Expanded. According to the ''Journal Citation Reports'', the ''Journal of Agricultural and Food Chemistry'' has a 2015 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a type of journal ranking. Journals with higher impact factor values are considered more prestigious or imp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
