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Robert H. Shapiro
Robert H. Shapiro (July 18, 1935 – August 21, 2004) was an American chemist. Shapiro was educated at the Stanford University, where he received his MS and Ph. D. In 1965 he became professor at the University of Colorado at Boulder, and from 1980 until his retirement in 1989 he worked at the James Madison University. He then became dean at the United States Naval Academy The United States Naval Academy (US Naval Academy, USNA, or Navy) is a United States Service academies, federal service academy in Annapolis, Maryland. It was established on 10 October 1845 during the tenure of George Bancroft as Secretary of ... until his retirement in 1998. References 1935 births 2004 deaths 20th-century American chemists Stanford University alumni {{US-chemist-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Robert Shapiro (chemist)
Robert Shapiro (28 November 1935 – 15 June 2011) was professor emeritus of chemistry at New York University. He is best known for his work on the origin of life, having written two books on the topic: ''Origins, a Skeptic’s Guide to the Creation of Life on Earth'' (1986) and ''Planetary Dreams'' (1999). He opposed the RNA world hypothesis, and held that the spontaneous emergence of a molecule as complicated as RNA is highly unlikely. Instead, he proposed that life arose from some self-sustaining and compartmentalized reaction of simple molecules: "metabolism first" instead of "RNA first". This reaction would have to be able to reproduce and evolve, eventually leading to RNA. He claimed that in this view life is a normal consequence of the laws of nature and potentially quite common in the universe.Alvin PowellNYU chemist Robert Shapiro decries RNA-first possibility ''Harvard University Gazette'', 23 October 2008 Works *''Life Beyond Earth: The Intelligent Earthling's Guide to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
New Haven, Connecticut
New Haven is a city in the U.S. state of Connecticut. It is located on New Haven Harbor on the northern shore of Long Island Sound in New Haven County, Connecticut and is part of the New York City metropolitan area. With a population of 134,023 as determined by the 2020 United States census, 2020 U.S. census, New Haven is the third largest city in Connecticut after Bridgeport, Connecticut, Bridgeport and Stamford, Connecticut, Stamford and the principal municipality of Greater New Haven, which had a total 2020 population of 864,835. New Haven was one of the first Planned community, planned cities in the U.S. A year after its founding by English Puritans in 1638, eight streets were laid out in a four-by-four Grid plan, grid, creating the "Nine Square Plan". The central common block is New Haven Green, the New Haven Green, a square at the center of Downtown New Haven. The Green is now a National Historic Landmark, and the "Nine Square Plan" is recognized by the American Planning ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harrisonburg, Virginia
Harrisonburg is an independent city in the Shenandoah Valley region of the Commonwealth of Virginia in the United States. It is also the county seat of the surrounding Rockingham County, although the two are separate jurisdictions. At the 2020 census, the population was 51,814. The Bureau of Economic Analysis combines the city of Harrisonburg with Rockingham County for statistical purposes into the Harrisonburg, Virginia Metropolitan Statistical Area, which had an estimated population of 126,562 in 2011. Harrisonburg is home to James Madison University (JMU), a public research university with an enrollment of over 20,000 students, and Eastern Mennonite University (EMU), a private, Mennonite-affiliated liberal arts university. Although the city has no historical association with President James Madison, JMU was nonetheless named in his honor as Madison College in 1938 and renamed as James Madison University in 1977. EMU largely owes its existence to the sizable Mennonite ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Colorado At Boulder
The University of Colorado Boulder (CU Boulder, CU, or Colorado) is a public research university in Boulder, Colorado. Founded in 1876, five months before Colorado became a state, it is the flagship university of the University of Colorado system. CU Boulder is a member of the Association of American Universities, a selective group of major research universities in North America, and is classified among R1: Doctoral Universities – Very high research activity. In 2021, the university attracted support of over $634 million for research and spent $536 million on research and development according to the National Science Foundation, ranking it 50th in the nation. The university consists of nine colleges and schools and offers over 150 academic programs, enrolling more than 35,000 students as of January 2022. To date, 5 Nobel Prize laureates, 10 Pulitzer Prize winners, 11 MacArthur "Genius Grant" recipients, 1 Turing Award laureate, and 20 astronauts have been affiliate ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
James Madison University
James Madison University (JMU, Madison, or James Madison) is a public research university in Harrisonburg, Virginia. Founded in 1908 as the State Normal and Industrial School for Women at Harrisonburg, the institution was renamed Madison College in 1938 in honor of President James Madison and then James Madison University in 1977. It is situated in the Shenandoah Valley, just west of Massanutten Mountain. History Founded in 1908 as a women's college, James Madison University was established by the Virginia General Assembly. It was originally called The State Normal and Industrial School for Women at Harrisonburg. In 1914, the name of the university was changed to the State Normal School for Women at Harrisonburg. At first, academic offerings included only today's equivalent of technical training or junior college courses, but authorization to award bachelor's degrees was granted in 1916. During this initial period of development, the campus plan was established and six b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
United States Naval Academy
The United States Naval Academy (US Naval Academy, USNA, or Navy) is a United States Service academies, federal service academy in Annapolis, Maryland. It was established on 10 October 1845 during the tenure of George Bancroft as Secretary of the Navy. The Naval Academy is the second oldest of the five United States service academies, U.S. service academies and it educates midshipmen for service in the officer corps of the United States Navy and United States Marine Corps. The campus is located on the former grounds of Fort Severn at the confluence of the Severn River (Maryland), Severn River and Chesapeake Bay in Anne Arundel County, Maryland, Anne Arundel County, east of Washington, D.C., and southeast of Baltimore. The entire campus, known colloquially as the Yard, is a National Historic Landmark and home to many historic sites, buildings, and monuments. It replaced Philadelphia Naval Asylum, in Philadelphia, that had served as the first United States Naval Academy from 1 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stanford University
Stanford University, officially Leland Stanford Junior University, is a Private university, private research university in Stanford, California. The campus occupies , among the largest in the United States, and enrolls over 17,000 students. Stanford is considered among the most prestigious universities in the world. Stanford was founded in 1885 by Leland Stanford, Leland and Jane Stanford in memory of their only child, Leland Stanford Jr., who had died of typhoid fever at age 15 the previous year. Leland Stanford was a List of United States senators from California, U.S. senator and former List of governors of California, governor of California who made his fortune as a Big Four (Central Pacific Railroad), railroad tycoon. The school admitted its first students on October 1, 1891, as a Mixed-sex education, coeducational and non-denominational institution. Stanford University struggled financially after the death of Leland Stanford in 1893 and again after much of the campus was ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Shapiro Reaction
The Shapiro reaction or tosylhydrazone decomposition is an organic reaction in which a ketone or aldehyde is converted to an alkene through an intermediate hydrazone in the presence of 2 equivalents of organolithium reagent. The reaction was discovered by Robert H. Shapiro in 1967. The Shapiro reaction was used in the Nicolaou Taxol total synthesis. This reaction is very similar to the Bamford–Stevens reaction, which also involves the basic decomposition of tosyl hydrazones. Reaction mechanism In a prelude to the actual Shapiro reaction, a ketone or an aldehyde (1) is reacted with ''p''-toluenesulfonylhydrazide(2) to form a ''p''-toluenesulfonylhydrazone (or tosylhydrazone) which is a hydrazone (3). Two equivalents of strong base such as ''n''-butyllithium abstract the proton from the hydrazone (4) followed by the less acidic proton α to the hydrazone carbon (5), forming a carbanion. The carbanion then undergoes an elimination reaction producing a carbon–carbon double ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1935 Births
Events January * January 7 – Italian premier Benito Mussolini and French Foreign Minister Pierre Laval conclude Franco-Italian Agreement of 1935, an agreement, in which each power agrees not to oppose the other's colonial claims. * January 12 – Amelia Earhart becomes the first person to successfully complete a solo flight from Hawaii to California, a distance of 2,408 miles. * January 13 – A plebiscite in the Saar (League of Nations), Territory of the Saar Basin shows that 90.3% of those voting wish to join Germany. * January 24 – The first canned beer is sold in Richmond, Virginia, United States, by Gottfried Krueger Brewing Company. February * February 6 – Parker Brothers begins selling the board game Monopoly (game), Monopoly in the United States. * February 13 – Richard Hauptmann is convicted and sentenced to death for the kidnapping and murder of Charles Lindbergh Jr. in the United States. * February 15 – The discovery and clinical development of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2004 Deaths
This is a list of deaths of notable people, organised by year. New deaths articles are added to their respective month (e.g., Deaths in ) and then linked here. 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 See also * Lists of deaths by day * Deaths by year {{DEFAULTSORT:deaths by year ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
