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RBE
In radiobiology, the relative biological effectiveness (often abbreviated as RBE) is the ratio of biological effectiveness of one type of ionizing radiation relative to another, given the same amount of absorbed energy. The RBE is an empirical value that varies depending on the type of ionizing radiation, the energies involved, the biological effects being considered such as cell death, and the oxygen tension of the tissues or so-called oxygen effect. Application The absorbed dose can be a poor indicator of the biological effect of radiation, as the biological effect can depend on many other factors, including the type of radiation, energy, and type of tissue. The relative biological effectiveness can help give a better measure of the biological effect of radiation. The relative biological effectiveness for radiation of type ''R'' on a tissue is defined as the ratio :RBE= \frac where ''D''''X'' is a reference absorbed dose of radiation of a standard type ''X'', and ''D'''' ...
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Rbe Definition
In radiobiology, the relative biological effectiveness (often abbreviated as RBE) is the ratio of biological effectiveness of one type of ionizing radiation relative to another, given the same amount of absorbed energy. The RBE is an empirical value that varies depending on the type of ionizing radiation, the energies involved, the biological effects being considered such as cell death, and the oxygen tension of the tissues or so-called oxygen effect. Application The absorbed dose can be a poor indicator of the biological effect of radiation, as the biological effect can depend on many other factors, including the type of radiation, energy, and type of tissue. The relative biological effectiveness can help give a better measure of the biological effect of radiation. The relative biological effectiveness for radiation of type ''R'' on a tissue is defined as the ratio :RBE= \frac where ''D''''X'' is a reference absorbed dose of radiation of a standard type ''X'', and ''D''''R ...
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Linear Energy Transfer
In dosimetry, linear energy transfer (LET) is the amount of energy that an ionizing particle transfers to the material traversed per unit distance. It describes the action of radiation into matter. It is identical to the retarding force acting on a charged ionizing particle travelling through the matter. By definition, LET is a positive quantity. LET depends on the nature of the radiation as well as on the material traversed. A high LET will attenuate the radiation more quickly, generally making shielding more effective and preventing deep penetration. On the other hand, the higher concentration of deposited energy can cause more severe damage to any microscopic structures near the particle track. If a microscopic defect can cause larger-scale failure, as is the case in biological cells and microelectronics, the LET helps explain why radiation damage is sometimes disproportionate to the absorbed dose. Dosimetry attempts to factor in this effect with radiation weighting fac ...
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Rem (unit)
The roentgen equivalent man (rem) is a CGS unit of equivalent dose, effective dose, and committed dose, which are dose measures used to estimate potential health effects of low levels of ionizing radiation on the human body. Quantities measured in rem are designed to represent the stochastic biological risk of ionizing radiation, which is primarily radiation-induced cancer. These quantities are derived from absorbed dose, which in the CGS system has the unit rad. There is no universally applicable conversion constant from rad to rem; the conversion depends on relative biological effectiveness (RBE). The rem has been defined since 1976 as equal to 0.01  sievert, which is the more commonly used SI unit outside the United States. Earlier definitions going back to 1945 were derived from the roentgen unit, which was named after Wilhelm Röntgen, a German scientist who discovered X-rays. The unit name is misleading, since 1 roentgen actually deposits about 0.96 rem in soft b ...
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International Commission On Radiological Protection
The International Commission on Radiological Protection (ICRP) is an independent, international, non-governmental organization, with the mission to protect people, animals, and the environment from the harmful effects of ionising radiation. Its recommendations form the basis of radiological protection policy, regulations, guidelines and practice worldwide. The ICRP was effectively founded in 1928 at the second International Congress of Radiology in Stockholm, Sweden but was then called the International X-ray and Radium Protection Committee (IXRPC). In 1950 it was restructured to take account of new uses of radiation outside the medical area and re-named as the ICRP. The ICRP is a sister organisation to the International Commission on Radiation Units and Measurements (ICRU). In general terms ICRU defines the units, and ICRP recommends, develops and maintains the International system of radiological protection which uses these units. Operation The ICRP is a not-for-profit or ...
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Effective Dose (radiation Safety)
Effective dose is a dose quantity in the International Commission on Radiological Protection (ICRP) system of radiological protection.ICRP publication, 103 para 103 It is the tissue-weighted sum of the equivalent doses in all specified tissues and organs of the human body and represents the stochastic health risk to the whole body, which is the ''probability'' of cancer induction and genetic effects, of low levels of ionizing radiation. It takes into account the type of radiation and the nature of each organ or tissue being irradiated, and enables summation of organ doses due to varying levels and types of radiation, both internal and external, to produce an overall calculated effective dose. The SI unit for effective dose is the sievert (Sv) which represents a 5.5% chance of developing cancer. The effective dose is not intended as a measure of ''deterministic'' health effects, which is the ''severity'' of acute tissue damage that is certain to happen, that is measured by the quan ...
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SI Radiation Dose Units
The International System of Units, known by the international abbreviation SI in all languages and sometimes pleonastically as the SI system, is the modern form of the metric system and the world's most widely used system of measurement. Established and maintained by the General Conference on Weights and Measures (CGPM), it is the only system of measurement with an official status in nearly every country in the world, employed in science, technology, industry, and everyday commerce. The SI comprises a coherent system of units of measurement starting with seven base units, which are the second (symbol s, the unit of time), metre (m, length), kilogram (kg, mass), ampere (A, electric current), kelvin (K, thermodynamic temperature), mole (mol, amount of substance), and candela (cd, luminous intensity). The system can accommodate coherent units for an unlimited number of additional quantities. These are called coherent derived units, which can always be represented as produ ...
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Prokaryote
A prokaryote () is a single-celled organism that lacks a nucleus and other membrane-bound organelles. The word ''prokaryote'' comes from the Greek πρό (, 'before') and κάρυον (, 'nut' or 'kernel').Campbell, N. "Biology:Concepts & Connections". Pearson Education. San Francisco: 2003. In the two-empire system arising from the work of Édouard Chatton, prokaryotes were classified within the empire Prokaryota. But in the three-domain system, based upon molecular analysis, prokaryotes are divided into two domains: ''Bacteria'' (formerly Eubacteria) and '' Archaea'' (formerly Archaebacteria). Organisms with nuclei are placed in a third domain, Eukaryota. In the study of the origins of life, prokaryotes are thought to have arisen before eukaryotes. Besides the absence of a nucleus, prokaryotes also lack mitochondria, or most of the other membrane-bound organelles that characterize the eukaryotic cell. It was once thought that prokaryotic cellular components within the ...
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Culture Medium
A growth medium or culture medium is a solid, liquid, or semi-solid designed to support the growth of a population of microorganisms or cells via the process of cell proliferation or small plants like the moss '' Physcomitrella patens''. Different types of media are used for growing different types of cells. The two major types of growth media are those used for cell culture, which use specific cell types derived from plants or animals, and those used for microbiological culture, which are used for growing microorganisms such as bacteria or fungi. The most common growth media for microorganisms are nutrient broths and agar plates; specialized media are sometimes required for microorganism and cell culture growth. Some organisms, termed fastidious organisms, require specialized environments due to complex nutritional requirements. Viruses, for example, are obligate intracellular parasites and require a growth medium containing living cells. Types The most common growth med ...
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Effective Dose (radiation)
Effective dose is a dose quantity in the International Commission on Radiological Protection (ICRP) system of radiological protection.ICRP publication, 103 para 103 It is the tissue-weighted sum of the equivalent doses in all specified tissues and organs of the human body and represents the stochastic health risk to the whole body, which is the ''probability'' of cancer induction and genetic effects, of low levels of ionizing radiation. It takes into account the type of radiation and the nature of each organ or tissue being irradiated, and enables summation of organ doses due to varying levels and types of radiation, both internal and external, to produce an overall calculated effective dose. The SI unit for effective dose is the sievert (Sv) which represents a 5.5% chance of developing cancer. The effective dose is not intended as a measure of ''deterministic'' health effects, which is the ''severity'' of acute tissue damage that is certain to happen, that is measured by the qu ...
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Neutron Radiation Weighting Factor As A Function Of Kinetic Energy
The neutron is a subatomic particle, symbol or , which has a neutral (not positive or negative) charge, and a mass slightly greater than that of a proton. Protons and neutrons constitute the nuclei of atoms. Since protons and neutrons behave similarly within the nucleus, and each has a mass of approximately one atomic mass unit, they are both referred to as nucleons. Their properties and interactions are described by nuclear physics. Protons and neutrons are not elementary particles; each is composed of three quarks. The chemical properties of an atom are mostly determined by the configuration of electrons that orbit the atom's heavy nucleus. The electron configuration is determined by the charge of the nucleus, which is determined by the number of protons, or atomic number. The number of neutrons is the neutron number. Neutrons do not affect the electron configuration, but the sum of atomic and neutron numbers is the mass of the nucleus. Atoms of a chemical element that ...
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Sievert
The sievert (symbol: SvNot be confused with the sverdrup or the svedberg, two non-SI units that sometimes use the same symbol.) is a unit in the International System of Units (SI) intended to represent the stochastic health risk of ionizing radiation, which is defined as the probability of causing radiation-induced cancer and genetic damage. The sievert is important in dosimetry and radiation protection. It is named after Rolf Maximilian Sievert, a Swedish medical physicist renowned for work on radiation dose measurement and research into the biological effects of radiation. The sievert is used for radiation dose quantities such as equivalent dose and effective dose, which represent the risk of external radiation from sources outside the body, and committed dose, which represents the risk of internal irradiation due to inhaled or ingested radioactive substances. According to the International Commission on Radiological Protection (ICRP) one sievert results in a 5.5% probabilit ...
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