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Punta Toro Phlebovirus
Punta Toro virus is a member of the genus ''Phlebovirus'' of the family ''Phenuiviridae''. It was initially isolated from patients in Colombia and two key patients in Panama Panama, officially the Republic of Panama, is a country in Latin America at the southern end of Central America, bordering South America. It is bordered by Costa Rica to the west, Colombia to the southeast, the Caribbean Sea to the north, and .... Two individual serotypes of PTV were isolated from these patients, PTV-Adames (A) and PTV-Balliet (B), with PTV-A appearing to be more virulent. PTV is considered to be relatively contained to the Americas with no cases being reported outside of this region. Along with a few other human pathogenic phleboviruses, PTV is considered to be a significant virus in terms of public health as little information is known about its clinical effects and with further research underway, PTV could have unforeseen impacts on health and virology. Structure PTV possesses m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phlebovirus
''Phlebovirus'' is a genus of viruses in the family '' Phenuiviridae'' in the order '' Hareavirales''. The genus contains 67 species. It derives its name from Phlebotominae, the vectors of member species Sandfly fever Naples virus, which is said to be ultimately from the Greek , meaning "vein". The proper word for "vein" in ancient Greek is however ''phleps'' (φλέψ). Virology Phleboviruses are viruses with a negative-sense RNA genome consisting of three segments. The small segment (S) codes for the viral N protein and a non structural protein, NSs via an ambisense coding strategy. The medium-sized segment (M) codes for a precursor of the viral glycoproteins and non-structural components. The product of the largest segment (L) is the viral RNA-dependent RNA polymerase. Replication Phleboviruses replicate in a seven step process. First, the cellular attachment is driven through the glycoprotein interactions with host cells. Examples of this are Dendritic Cell-Specific ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phenuiviridae
''Phenuiviridae'' is a family of negative-strand RNA viruses in the order '' Hareavirales''. Ruminants, camels, humans, and mosquitoes serve as natural hosts. Virology Structure Members of ''Phenuiviridae are'' enveloped viruses with helical capsid morphology. Envelope glycoproteins of these viruses are distributed with icosahedral symmetry (T=12). Genome ''Phenuiviridae'' is a negative-sense single-stranded RNA virus family. Its genome is segmented into three pieces: L segment (encoding RNA-dependent RNA polymerase), M segment, and S segment. Some members of the family have ambisense gene encoding on the S segment ( nucleocapsid proteins). The M segment includes envelope glycoproteins encoded in a polyprotein that is cleaved by host proteases. Multiple different proteins can be encoded on the M segment due to leaky scanning by the ribosome. Life cycle RNA transcripts are capped through cap snatching, but not polyadenylated. Translation Translation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Colombia
Colombia, officially the Republic of Colombia, is a country primarily located in South America with Insular region of Colombia, insular regions in North America. The Colombian mainland is bordered by the Caribbean Sea to the north, Venezuela to the east and northeast, Brazil to the southeast, Peru and Ecuador to the south and southwest, the Pacific Ocean to the west, and Panama to the northwest. Colombia is divided into 32 Departments of Colombia, departments. The Capital District of Bogotá is also the List of cities in Colombia by population, country's largest city hosting the main financial and cultural hub. Other major urban areas include Medellín, Cali, Barranquilla, Cartagena, Colombia, Cartagena, Santa Marta, Cúcuta, Ibagué, Villavicencio and Bucaramanga. It covers an area of 1,141,748 square kilometers (440,831 sq mi) and has a population of around 52 million. Its rich cultural heritage—including language, religion, cuisine, and art—reflects its history as a co ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Panama
Panama, officially the Republic of Panama, is a country in Latin America at the southern end of Central America, bordering South America. It is bordered by Costa Rica to the west, Colombia to the southeast, the Caribbean Sea to the north, and the Pacific Ocean to the south. Its capital and largest city is Panama City, whose metropolitan area is home to nearly half of the country's over million inhabitants. Before the arrival of Spanish Empire, Spanish colonists in the 16th century, Panama was inhabited by a number of different Indigenous peoples of Panama, indigenous tribes. It Independence Act of Panama, broke away from Spain in 1821 and joined the Republic of Gran Colombia, a union of Viceroyalty of New Granada, Nueva Granada, Ecuador, and Venezuela. After Gran Colombia dissolved in 1831, Panama and Nueva Granada eventually became the Republic of Colombia. With the backing of the United States, Panama seceded from Colombia in 1903, allowing the construction of the Panama Ca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
