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Phlebovirus
''Phlebovirus'' is a genus of viruses in the family '' Phenuiviridae'' in the order '' Hareavirales''. The genus contains 67 species. It derives its name from Phlebotominae, the vectors of member species Sandfly fever Naples virus, which is said to be ultimately from the Greek , meaning "vein". The proper word for "vein" in ancient Greek is however ''phleps'' (φλέψ). Virology Phleboviruses are viruses with a negative-sense RNA genome consisting of three segments. The small segment (S) codes for the viral N protein and a non structural protein, NSs via an ambisense coding strategy. The medium-sized segment (M) codes for a precursor of the viral glycoproteins and non-structural components. The product of the largest segment (L) is the viral RNA-dependent RNA polymerase. Replication Phleboviruses replicate in a seven step process. First, the cellular attachment is driven through the glycoprotein interactions with host cells. Examples of this are Dendritic Cell-Specific ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Candiru Phlebovirus
Candiru virus (CDUV) is a species of virus in the genus ''Phlebovirus''. Related strains CDUV forms a serocomplex of related viruses with other phlebovirus strains (not italicized) and species (italicized), including: * Alenquer virus * Ariquemes virus * Echarate virus * Itaituba virus * Jacunda virus * Maldonado virus * Morumbi virus * Mucura virus * Nique virus * Oriximina virus * Serra Norte virus * Turuna virus The serocomplex, CDUV, Alenquer, Echarate, Maldonado, Morumbi, and Serra Norte were isolated from people experiencing febrile illness, whereas the others were isolated from mosquitoes and sandflies. References Phleboviruses {{Virus-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Punta Toro Virus
Punta Toro virus is a member of the genus ''Phlebovirus'' of the family ''Phenuiviridae''. It was initially isolated from patients in Colombia and two key patients in Panama Panama, officially the Republic of Panama, is a country in Latin America at the southern end of Central America, bordering South America. It is bordered by Costa Rica to the west, Colombia to the southeast, the Caribbean Sea to the north, and .... Two individual serotypes of PTV were isolated from these patients, PTV-Adames (A) and PTV-Balliet (B), with PTV-A appearing to be more virulent. PTV is considered to be relatively contained to the Americas with no cases being reported outside of this region. Along with a few other human pathogenic phleboviruses, PTV is considered to be a significant virus in terms of public health as little information is known about its clinical effects and with further research underway, PTV could have unforeseen impacts on health and virology. Structure PTV possesses m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sandfly Fever Naples Virus
Sandfly fever Naples virus is an antigenic species of genus ''Phlebovirus'' within the family ''Phenuiviridae'' of the order '' Hareavirales''. It is an enveloped RNA virus with a tripartite genome. Its natural reservoir are sandflies. The SFNV serogroup consists of two main serocomplexes associated with disease in humans, the Naples and Sicilian serocomplexes. Sandfly fever induces myalgia, fever, and elevated liver enzymes in humans. It is difficult to diagnose outside endemic areas. Natural reservoir Phlebotomine sandflies (Psychodidae Psychodidae, also called drain flies, sink flies, filter flies, sewer flies, or sewer gnats, is a Family (biology), family of Fly, true flies. Some genera have short, hairy bodies and wings, giving them a "furry" moth-like appearance, hence one ...) are the natural reservoir and transmit to humans via bite. Psychodidae has a wide geographical distribution. References External links Sandfly fever Naples virus taxonomy* Database search r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rift Valley Fever
Rift Valley fever (RVF) is a viral disease of humans and livestock that can cause mild to severe symptoms. The mild symptoms may include: fever, muscle pains, and headaches which often last for up to a week. The severe symptoms may include: loss of sight beginning three weeks after the infection, infections of the brain causing severe headaches and confusion, and bleeding together with liver problems which may occur within the first few days. Those who have bleeding have a chance of death as high as 50%. The disease is caused by the RVF virus. It is spread by either touching infected animal blood, breathing in the air around an infected animal being butchered, drinking raw milk from an infected animal, or the bite of infected mosquitoes. Animals like cows, sheep, goats, and camels may be affected. In these animals it is spread mostly by mosquitoes. It does not appear that one person can infect another. The disease is diagnosed by finding antibodies against the virus or the viru ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phenuiviridae
''Phenuiviridae'' is a family of negative-strand RNA viruses in the order '' Hareavirales''. Ruminants, camels, humans, and mosquitoes serve as natural hosts. Virology Structure Members of ''Phenuiviridae are'' enveloped viruses with helical capsid morphology. Envelope glycoproteins of these viruses are distributed with icosahedral symmetry (T=12). Genome ''Phenuiviridae'' is a negative-sense single-stranded RNA virus family. Its genome is segmented into three pieces: L segment (encoding RNA-dependent RNA polymerase), M segment, and S segment. Some members of the family have ambisense gene encoding on the S segment ( nucleocapsid proteins). The M segment includes envelope glycoproteins encoded in a polyprotein that is cleaved by host proteases. Multiple different proteins can be encoded on the M segment due to leaky scanning by the ribosome. Life cycle RNA transcripts are capped through cap snatching, but not polyadenylated. Translation Translation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Toscana Virus
Toscana virus (TOSV) is an arbovirus (arthropod-borne virus) belonging to '' Bunyaviricetes'', a class of negative-stranded, enveloped RNA viruses. The virus can be transmitted to humans by the bite of an infected sandfly of the genus '' Phlebotomus''. Toscana is not normally associated with disease, as indicated by high seroprevalence rates (up to 25%) in endemic areas, but in common with other sandfly transmitted viruses such as '' Naples virus'' and '' Sicilian virus'', infection may result in Pappataci fever, an illness with mild fever, headache and myalgia. In serious cases that go undiagnosed, acute meningitis, meningoencephalitis and encephalitis may occur. There is no specific treatment for infection, so treatment is supportive, reducing the severity of symptoms until the immune system has cleared the infection. The virus is found in most countries that border the Mediterranean Sea, with the highest incidence in Italy. Infection rates peak during the summer time as sand ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alenquer Virus
Alenquer virus (ALEV) is a virus in the genus ''Phlebovirus''. Alenquer virus was one of eight arthropod-borne viruses first isolated in the early 1980s from sites along roads built into the Amazon rainforest in Brazil for settlers. Sporadic cases of febrile illness have occurred in humans who live in jungle areas in Brazil and Panama Panama, officially the Republic of Panama, is a country in Latin America at the southern end of Central America, bordering South America. It is bordered by Costa Rica to the west, Colombia to the southeast, the Caribbean Sea to the north, and .... References Phleboviruses Serology {{Virus-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chagres Virus
Chagres (), once the chief Atlantic port on the isthmus of Panama, is now an abandoned village at the historical site of Fort San Lorenzo (). The fort's ruins and the village site are located about west of Colón, on a promontory overlooking the mouth of the Chagres River. 16th and 17th centuries: Discovery and fortification In 1502, during his fourth and final voyage, Christopher Columbus discovered the Chagres River. By 1534, the Monarchy of Spain had, following its conquest of Peru, established a rainy-season gold route over the isthmus of Panama—Camino Real de Cruces—using mule trains and the Chagres River. The trail connected the Pacific port of Panama City to the mouth of the Chagres, from whence Peru's plunder would sail to Spain's storehouses in the leading Atlantic ports of the isthmus: Nombre de Dios, at first; and, later, Portobelo. (The dry-season, overland route—the Camino Real—connected Panama City with those ports directly.) Attracted to the treasu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Taxonomy
image:Hierarchical clustering diagram.png, 280px, Generalized scheme of taxonomy Taxonomy is a practice and science concerned with classification or categorization. Typically, there are two parts to it: the development of an underlying scheme of classes (a taxonomy) and the allocation of things to the classes (classification). Originally, taxonomy referred only to the Taxonomy (biology), classification of organisms on the basis of shared characteristics. Today it also has a more general sense. It may refer to the classification of things or concepts, as well as to the principles underlying such work. Thus a taxonomy can be used to organize species, documents, videos or anything else. A taxonomy organizes taxonomic units known as "taxa" (singular "taxon"). Many are hierarchy, hierarchies. One function of a taxonomy is to help users more easily find what they are searching for. This may be effected in ways that include a library classification system and a Taxonomy for search e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sandfly Turkey Virus
Sandfly or sand fly is a colloquial name for any species or genus of flying, biting, blood-sucking dipteran (fly) encountered in sandy areas. In the United States, ''sandfly'' may refer to certain horse flies that are also known as "greenheads" (family ''Tabanidae''), or to members of the family ''Ceratopogonidae''. The bites usually result in a small, intensely itchy bump or welt, the strength of which intensifies over a period of 5-7 days before dissipating. Sandfly bites can be distinguished from mosquito bites as sandfly bite are usually found in clusters as they attack animals in groups. Moderate relief is achieved with varying success through the application of over-the-counter products such as Benadryl (ingested) or an analgesic cream such as After Bite (applied topically). Outside the United States, ''sandfly'' may refer to members of the subfamily Phlebotominae within the Psychodidae. Biting midges (Ceratopogonidae) are sometimes called sandflies or no-see-ums (no-se ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Viral Encephalitis
Viral encephalitis is inflammation of the brain parenchyma, called encephalitis, by a virus. The different forms of viral encephalitis are called viral encephalitides. It is the most common type of encephalitis and often occurs with viral meningitis. Encephalitic viruses first cause infection and replicate outside of the central nervous system (CNS), most reaching the CNS through the circulatory system and a minority from nerve endings toward the CNS. Once in the brain, the virus and the host's inflammatory response disrupt neural function, leading to illness and complications, many of which frequently are neurological in nature, such as impaired motor skills and altered behavior. Viral encephalitis can be diagnosed based on the individual's symptoms, personal history, such as travel history, and different clinical tests such as histology, medical imaging, and lumbar punctures. A differential diagnosis can also be done to rule out other causes of the encephalitis. Many encephalitic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
