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Pentamethoxyamphetamine
Pentamethoxyamphetamine (PeMA), also known as 2,3,4,5,6-pentamethoxyamphetamine (2,3,4,5,6-PeMA), is a chemical compound of the phenethylamine and amphetamine families related to the psychedelic drug mescaline (3,4,5-trimethoxyphenethylamine). It is the α-methyl or amphetamine derivative of pentamethoxyphenethylamine (PeMPEA). The compound does not seem to have been tested in animals or humans. However, the related drug PeMPEA is known to be behaviorally active in animal studies. PeMA was first described in the scientific literature by Alexander Shulgin by 1969. See also * Substituted methoxyphenethylamine * Pentamethoxyphenethylamine * Tetramethoxyamphetamine * Tetramethoxyphenethylamine * Trimethoxyamphetamine 3,4,5-Trimethoxyamphetamine (TMA, TMA-1, or 3,4,5-TMA), also known as α-methylmescaline or mescalamphetamine, is a psychedelic drug of the phenethylamine and amphetamine families. It is one of the trimethoxyamphetamine (TMA) series of positiona ... * Dimethoxymethyl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dimethoxymethylenedioxyamphetamine
Dimethoxymethylenedioxyamphetamine (DMMDA) may refer to: * 2,5-Dimethoxy-3,4-methylenedioxyamphetamine (DMMDA or DMMDA-1; 2,5-dimethoxy-MDA) * 2,3-Dimethoxy-4,5-methylenedioxyamphetamine (DMMDA-2; 5,6-dimethoxy-MDA) * 4,5-Dimethoxy-2,3-methylenedioxyamphetamine (DMMDA-3; 4,5-dimethoxy-ORTHO-MDA) * 2,6-Dimethoxy-3,4-methylenedioxyamphetamine (DMMDA-4; 2,6-dimethoxy-MDA) * 4,6-Dimethoxy-2,3-methylenedioxyamphetamine (DMMDA-5; 4,6-dimethoxy-ORTHO-MDA) * 2,3-Dimethoxy-5,6-methylenedioxyamphetamine (DMMDA-6; 5,6-dimethoxy-ORTHO-MDA) See also * Methoxymethylenedioxyamphetamine * Substituted methylenedioxyphenethylamine * Substituted methoxyphenethylamine * Pentamethoxyamphetamine Pentamethoxyamphetamine (PeMA), also known as 2,3,4,5,6-pentamethoxyamphetamine (2,3,4,5,6-PeMA), is a chemical compound of the phenethylamine and amphetamine families related to the psychedelic drug mescaline (3,4,5-trimethoxyphenethylamine). It ... {{Phenethylamines Methoxy compounds Methylenedio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pentamethoxyphenethylamine
Pentamethoxyphenethylamine (PeMPEA), also known as 2,3,4,5,6-pentamethoxyphenethylamine (2,3,4,5,6-PeMPEA), is a drug of the phenethylamine family related to the psychedelic drug mescaline (3,4,5-trimethoxyphenethylamine). It has been found to produce behavioral effects in animals, with about 8-fold higher potency than mescaline in the conditioned avoidance response test. The pharmacokinetics of the drug in rodents have been studied. The effects of PeMPEA in humans have not been reported and are unknown. It was first described in the scientific literature by 1955. PeMPEA was included as an entry in Alexander Shulgin's 2011 book '' The Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds''. See also * Substituted methoxyphenethylamine * Pentamethoxyamphetamine (PeMA) * 2,3,4,5-Tetramethoxyphenethylamine 2,3,4,5-Tetramethoxyphenethylamine (TeMPEA) is a drug of the phenethylamine family related to mescaline (3,4,5-trimethoxyphenethylamine) and the 2C dr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Substituted Methoxyphenethylamine
Methoxyphenethylamines (MPEAs), as well as methoxyamphetamines (MAs) in the case of the amphetamine (α-methylphenethylamine) homologues, are substituted phenethylamines with one or more methoxy groups. In some cases, one or more of the methoxy groups may also be extended to form other alkoxy and related groups such as ethoxy or propoxy. Methoxyphenethylamines may have additional substitutions as well. Many methoxyphenethylamines that have multiple methoxy groups in the 2- through 5-positions of the phenyl ring, for instance mescaline, 2C-B, TMA, DOM, and 25I-NBOMe, are serotonin 5-HT2A receptor agonists and serotonergic psychedelics. Other methoxyphenethylamines, particularly monomethoxyamphetamines like ''para''-methoxyamphetamine (PMA), are monoamine releasing agents of serotonin, norepinephrine, and/or dopamine, with stimulant and/or entactogen-related effects. Compounds closely related to methoxyphenethylamines include methylenedioxyphenethylamines (MDxx) like M ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemical Compound
A chemical compound is a chemical substance composed of many identical molecules (or molecular entities) containing atoms from more than one chemical element held together by chemical bonds. A molecule consisting of atoms of only one element is therefore not a compound. A compound can be transformed into a different substance by a chemical reaction, which may involve interactions with other substances. In this process, bonds between atoms may be broken or new bonds formed or both. There are four major types of compounds, distinguished by how the constituent atoms are bonded together. Molecular compounds are held together by covalent bonds; ionic compounds are held together by ionic bonds; intermetallic compounds are held together by metallic bonds; coordination complexes are held together by coordinate covalent bonds. Non-stoichiometric compounds form a disputed marginal case. A chemical formula specifies the number of atoms of each element in a compound molecule, usin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alexander Shulgin
Alexander Theodore "Sasha" Shulgin (June 17, 1925 – June 2, 2014) was an American biochemist, broad researcher of synthetic psychoactive compounds, and author of works regarding these, who independently explored the organic chemistry and pharmacology of such agents—in his mid-life and later, many through preparation in his home laboratory, and testing on himself. He is acknowledged to have introduced to broader use, in the late 1970s, the previously-synthesized compound MDMA ("ecstasy"), in research psychopharmacology and in combination with conventional therapy, the latter through presentations and academic publications, including to psychologists; and for the rediscovery, occasional discovery, and regular synthesis and personal use and distribution, of possibly hundreds of Psychoactive drug, psychoactive compounds (for their Psychedelic drug, psychedelic and MDMA-like empathogenic bioactivity, bioactivities). As such, Shulgin is seen both as a pioneering and a controversi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
3C (psychedelics)
3C (3C-''x''), also known as 4-substituted 3,5-dimethoxyamphetamines, substituted 3,4,5-trimethoxyamphetamine (3,4,5-TMA or TMA-1) analogues, or 3C-scalines, is a general name for the family of psychedelic amphetamines containing methoxy groups at the 3 and 5 positions of the benzene ring. These compounds are analogues of 3,4,5-trimethoxyamphetamine (3,4,5-TMA or TMA-1). The 3C drugs are not the amphetamine counterparts of the 2C drugs, which are 4-substituted 2,5-dimethoxyphenethylamines. Instead, the DOx drugs, which are 4-substituted 2,5-dimethoxyamphetamines, are the amphetamine counterparts of the 2C drugs. The 3C drugs are the amphetamine counterparts of substituted mescaline analogues (4-substituted 3,5-dimethoxyphenethylamines). Moreover, in terms of naming with the "3C" prefix, the 3C drugs are generally actually derivatives of TMA-1 with the 4-position methoxy group extended rather than having any 4-position substituent. In this regard, they would be the 3,5-dime ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Trimethoxyamphetamine
3,4,5-Trimethoxyamphetamine (TMA, TMA-1, or 3,4,5-TMA), also known as α-methylmescaline or mescalamphetamine, is a psychedelic drug of the phenethylamine and amphetamine families. It is one of the trimethoxyamphetamine (TMA) series of positional isomers. The drug is notable in being the amphetamine (i.e., α-methylated) analogue of mescaline (3,4,5-trimethoxyphenethylamine). Use and effects TMA is a serotonergic psychedelic and produces hallucinogenic effects. It is said to be active at doses of 100 to 250mg and to have a duration of 6 to 8hours. For comparison, mescaline is typically used at doses of 200 to 500mg and is said to have a duration of 10 to 12hours or longer. TMA's positional isomer 2,4,5-trimethoxyamphetamine (2,4,5-TMA or TMA-2) is much more potent than TMA, with a dosage of 20 to 40mg and a duration of 8 to 12hours. Interactions Pharmacology TMA is a low-potency serotonin 5-HT2A receptor partial agonist, with an affinity (Ki) of >12,000nM, an of 1,7 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tetramethoxyphenethylamine
Tetramethoxyphenethylamines (TeMPEA) are a group of positional isomers of the psychedelic cactus alkaloid mescaline. Some of them are described in the book PiHKAL by Alexander Shulgin and Ann Shulgin. * 2,3,4,5-Tetramethoxyphenethylamine (TeMPEA-1) * TeMPEA-2 (2,3,4,6-tetramethoxyphenethylamine) * TeMPEA-3 (2,3,5,6-tetramethoxyphenethylamine) * BOM (drug) (3,4,5,β-tetramethoxyphenethylamine) See also * Substituted methoxyphenethylamine * Methoxyphenethylamine * Dimethoxyphenethylamine * Methoxyamphetamine * Dimethoxyamphetamine * Trimethoxyphenethylamine Trimethoxyphenethylamines (TMPEA) are a group of positional isomers of the psychedelic cactus alkaloid mescaline. Some of them are described in the book PiHKAL by Alexander Shulgin and Ann Shulgin. * 2,3,4-trimethoxyphenethylamine ( Isomescaline) * ... {{Phenethylamines Methoxyphenethylamines ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tetramethoxyamphetamine
Tetramethoxyamphetamine (TeMA), or 2,3,4,5-tetramethoxyamphetamine, is a lesser-known psychedelic drug and a substituted amphetamine. Tetramethoxyamphetamine was first synthesized by Alexander Shulgin. In his book '' PiHKAL (Phenethylamines i Have Known And Loved)'', the minimum dosage is listed as 50 mg, and the duration unknown. Tetramethoxyamphetamine produces a threshold, mydriasis, and a headache. Limited data exists about its pharmacological properties, metabolism, and toxicity. See also * Substituted methoxyphenethylamine Methoxyphenethylamines (MPEAs), as well as methoxyamphetamines (MAs) in the case of the amphetamine (α-methylphenethylamine) homologues, are substituted phenethylamines with one or more methoxy groups. In some cases, one or more of the methoxy ... * 2,3,4,5-Tetramethoxyphenethylamine (TeMPEA) * 2,5-Dimethoxy-3,4-methylenedioxyamphetamine (DMMDA) References External links Tetramethoxyamphetamine entry in ''PiHKAL''Tetramethoxyamphetamine ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Scientific Literature
Scientific literature encompasses a vast body of academic papers that spans various disciplines within the natural and social sciences. It primarily consists of academic papers that present original empirical research and theoretical contributions. These papers serve as essential sources of knowledge and are commonly referred to simply as "the literature" within specific research fields. The process of academic publishing involves disseminating research findings to a wider audience. Researchers submit their work to reputable journals or conferences, where it undergoes rigorous evaluation by experts in the field. This evaluation, known as peer review, ensures the quality, validity, and reliability of the research before it becomes part of the scientific literature. Peer-reviewed publications contribute significantly to advancing our understanding of the world and shaping future research endeavors. Original scientific research first published in scientific journals co ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Substituted Phenethylamine
Substituted phenethylamines (or simply phenethylamines) are a chemical class of organic compounds that are based upon the phenethylamine structure; the class is composed of all the derivative (chemistry), derivative compounds of phenethylamine which can be formed by replacing, or substitution reaction, substituting, one or more hydrogen atoms in the phenethylamine core structure with substituents. Phenylethylamines are also generally found to be central nervous system stimulants with many also being entactogens/empathogens, and hallucinogens. Structural classification The structural formula of any substituted phenethylamine contains a phenyl group, phenyl ring that is joined to an amino group, amino (NH) group via a two-carbon substituent, sidechain. Hence, any substituted phenethylamine can be classified according to the substitution of hydrogen atom, hydrogen (H) atoms on phenethylamine's phenyl ring, sidechain, or amino group with a moiety (chemistry), specific group of at ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
