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Para-Iodomethamphetamine
''para''-Iodomethamphetamine (PIMA), also known as 4-iodo-''N''-methylamphetamine (4-IMA) or as D-9, is a monoaminergic drug of the amphetamine family related to ''para''-chloroamphetamine (PCA). It is the ''N''-methyl analogue of ''para''-iodoamphetamine (PIA). The drug is active in producing behavioral effects in animals, including hallucinogen-like effects. However, it is unclear whether these effects actually represent hallucinogenic reactions. PIMA does not appear to have been assessed, but other ''para''-halogenated amphetamines, such as PCA, are known to act as monoamine releasing agents and as monoaminergic neurotoxins. They have not proved to be psychedelic in humans. PIMA was studied by Joseph Knoll and colleagues in the 1960s or 1970s. See also * Substituted amphetamine Substituted amphetamines, or simply amphetamines, are a chemical class, class of compounds based upon the amphetamine structure; it includes all derivative (chemistry), derivative compounds w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Monoaminergic
Monoaminergic means "working on monoamine neurotransmitters", which include serotonin, dopamine, norepinephrine, epinephrine, and histamine. A monoaminergic, or monoaminergic drug, is a chemical, which functions to directly modulate the serotonin, dopamine, norepinephrine, epinephrine, and/or histamine neurotransmitter systems in the brain. Monoaminergics include catecholaminergics (which can be further divided into adrenergics and dopaminergics), serotonergics, and histaminergics. Examples of monoaminergic drugs include monoamine precursors, monoamine receptor modulators, monoamine reuptake inhibitors, monoamine releasing agents, and monoamine metabolism modulators such as monoamine oxidase inhibitors. See also * Adenosinergic * Adrenergic * Cannabinoidergic * Cholinergic * Dopaminergic * GABAergic * Glycinergic * Histaminergic * Melatonergic A melatonergic agent (or drug) is a chemical which functions to directly modulate the melatonin system in the body or brain. Exam ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |