Ormeloxifene
Ormeloxifene, also known as centchroman, is one of the selective estrogen receptor modulators, or SERMs, a class of medication which acts on the estrogen receptor. It is best known as a nonsteroidal oral contraceptive which is taken once per week. In India, ormeloxifene has been available as birth control since the early 1990s, and it was marketed there under the trade name Saheli, currently available free-of-cost for the women in India as Chhaya (Centchroman). Ormeloxifene has also been licensed under the trade names Ormalin, Novex-DS, Centron, and Sevista. Medical uses Ormeloxifene is primarily used as a contraceptive but may also be effective for dysfunctional uterine bleeding and advanced breast cancer. Birth control Ormeloxifene may be used as a weekly oral contraceptive. The weekly schedule is an advantage for women who prefer an oral contraceptive, but find it difficult or impractical to adhere to a daily schedule required by other oral contraceptives. For the first ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Central Drug Research Institute
Central Drug Research Institute is a multidisciplinary research laboratory in Lucknow, India, employing scientific personnel from various areas of biomedical sciences. History The Central Drug Research Institute was one of the first laboratories to be established in India right after its independence. It is among the thirty nine laboratories that are functioning under the aegis of the Council of Scientific and Industrial Research of India. The research institute was formally inaugurated on 17 February 1951 by the Prime Minister of India, prime minister, Jawahar Lal Nehru. Divisions For administrative and scientific purposes the institute's manpower has been grouped into 17 research and development divisions and several divisions providing technical and scientific support. The following divisions of are involved in research and development: * Division of Biochemistry * Division of Botany * Clinical and Experimental Medicine * Division of Cancer Biology * Division of Endocrin ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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HLL Lifecare
HLL Lifecare Limited (formerly Hindustan Latex Limited) (HLL) is an Indian healthcare product manufacturing company based in Thiruvananthapuram, Kerala, India. It is a Government of India -owned corporation (public-sector undertaking). Products It produces health care products, including condoms, contraceptive pills, IUDs, surgical sutures, blood bags and Pharma products. One of HLL's contraceptive products is ormeloxifene, branded as '' Saheli'', the world's first and only oral non-hormonal, non-steroidal oral contraceptive, taken as a weekly pill. In 2012, HLL announced a polymerase chain reaction based duplex test kit for chikungunya and dengue fever tests in collaboration with the Rajiv Gandhi Centre for Biotechnology, Trivandrum. In December 2015, they tied up with the Government of India in setting up Amrit pharmacies across India for providing cheaper medicines for Cancer and Cardiovascular disorders. The name Amrit stands for Affordable Medicines and Reliable Impl ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Selective Estrogen Receptor Modulator
Selective estrogen receptor modulators (SERMs), also known as estrogen receptor agonists/antagonists (ERAAs), are a class of drugs that act on estrogen receptors (ERs). Compared to pure ER agonists–antagonists (e.g., full agonists and silent antagonists), SERMs are more tissue-specific, allowing them to selectively inhibit or stimulate estrogen-like action in various tissues. Medical uses SERMs are used for various estrogen-related diseases, including treatment of ovulatory dysfunction in the management of infertility treatment, prevention of postmenopausal osteoporosis, treatment and risk reduction of breast cancer, and treatment of dyspareunia due to menopause. SERMs are also used in combination with conjugated estrogens indicated for the management of estrogen deficiency symptoms and of vasomotor symptoms associated with menopause. SERMs are also being explored for gender-affirming hormone therapy in some non-binary transgender individuals that were assigned male a ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Oral Contraceptive
Oral contraceptives, abbreviated OCPs, also known as birth control pills, are medications taken by mouth for the purpose of birth control. The introduction of the birth control pill ("the Pill") in 1960 revolutionized the options for contraception, sparking vibrant discussion in the scientific and social science literature and in the media. Much attention focused on issues of women's rights, including ethics and personal choice. But these medications also introduced new questions about risk. Female Two types of female oral contraceptive pill, taken once per day, are widely available: * The combined oral contraceptive pill contains estrogen and a progestin; colloquially known as "the Pill". * The progestogen-only pill, colloquially known as "minipill". For perfect use it is 99% effective and typical use is 91% effective. Side effects of the pill include headache, dizziness, nausea, sore breasts, spotting, mood changes, acne, bloating, etc. One pill offers the benefit of only havi ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Breast
The breasts are two prominences located on the upper ventral region of the torso among humans and other primates. Both sexes develop breasts from the same embryology, embryological tissues. The relative size and development of the breasts is a major secondary sex distinction between females and males. There is also considerable Bra size, variation in size between individuals. Permanent Breast development, breast growth during puberty is caused by estrogens in conjunction with the growth hormone. Female humans are the only mammals that permanently develop breasts at puberty; all other mammals develop their mammary tissue during the latter period of pregnancy. In females, the breast serves as the mammary gland, which produces and secretes milk to feed infants. Subcutaneous fat covers and envelops a network of lactiferous duct, ducts that converge on the nipple, and these tissue (biology), tissues give the breast its distinct size and globular shape. At the ends of the ducts are ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Menstrual Cycle
The menstrual cycle is a series of natural changes in hormone production and the structures of the uterus and ovaries of the female reproductive system that makes pregnancy possible. The ovarian cycle controls the production and release of eggs and the cyclic release of estrogen and progesterone. The uterine cycle governs the preparation and maintenance of the lining of the uterus (womb) to receive an embryo. These cycles are concurrent and coordinated, normally last between 21 and 35 days, with a median length of 28 days. Menarche (the onset of the first period) usually occurs around the age of 12 years; menstrual cycles continue for about 30–45 years. Naturally occurring hormones drive the cycles; the cyclical rise and fall of the follicle stimulating hormone prompts the production and growth of oocytes (immature egg cells). The hormone estrogen stimulates the uterus lining ( endometrium) to thicken to accommodate an embryo should fertilization occur. The blood suppl ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Ovulation
Ovulation is an important part of the menstrual cycle in female vertebrates where the egg cells are released from the ovaries as part of the ovarian cycle. In female humans ovulation typically occurs near the midpoint in the menstrual cycle and after the follicular phase. Ovulation is stimulated by an increase in luteinizing hormone (LH). The ovarian follicles rupture and release the secondary oocyte ovarian cells. After ovulation, during the luteal phase, the egg will be available to be fertilized by sperm. If it is not, it will break down in less than a day. Meanwhile, the uterine lining ( endometrium) continues to thicken to be able to receive a fertilized egg. If no conception occurs, the uterine lining will eventually break down and be shed from the body via the vagina during menstruation. Some people choose to track ovulation in order to improve or aid becoming pregnant by timing intercourse with their ovulation. The signs of ovulation may include cervical muc ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Fallopian Tube
The fallopian tubes, also known as uterine tubes, oviducts or salpinges (: salpinx), are paired tubular sex organs in the human female body that stretch from the Ovary, ovaries to the uterus. The fallopian tubes are part of the female reproductive system. In other vertebrates, they are only called oviducts. Each tube is a muscular hollow organ that is on average between in length, with an external diameter of . It has four described parts: the intramural part, isthmus, ampulla, and infundibulum with associated fimbriae. Each tube has two openings: a proximal opening nearest to the uterus, and a distal opening nearest to the ovary. The fallopian tubes are held in place by the mesosalpinx, a part of the broad ligament mesentery that wraps around the tubes. Another part of the broad ligament, the mesovarium suspends the ovaries in place. An ovum, egg cell is transported from an ovary to a fallopian tube where it may be human fertilization, fertilized in the ampulla of the tube. ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Oral Administration
Oral administration is a route of administration whereby a substance is taken through the Human mouth, mouth, swallowed, and then processed via the digestive system. This is a common route of administration for many medications. Oral administration can be easier and less painful than other routes of administration, such as Injection (medicine), injection. However, the onset of action is relatively low, and the effectiveness is reduced if it is not absorbed properly in the digestive system, or if it is broken down by digestive enzymes before it can reach the bloodstream. Some medications may cause gastrointestinal side effects, such as nausea or vomiting, when taken orally. Oral administration can also only be applied to conscious patients, and patients able to swallow. Terminology ''Per os'' (; ''P.O.'') is an adverbial phrase meaning literally from Latin "through the mouth" or "by mouth". The expression is used in medicine to describe a treatment that is taken orally (but not ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Lucknow
Lucknow () is the List of state and union territory capitals in India, capital and the largest city of the List of state and union territory capitals in India, Indian state of Uttar Pradesh and it is the administrative headquarters of the eponymous Lucknow district, district and Lucknow division, division. Having a population of 2.8 million as per 2011 census, it is the List of cities in India by population, eleventh most populous city and List of million-plus urban agglomerations in India, the twelfth-most populous urban agglomeration of India. Lucknow has always been a Multiculturalism, multicultural city that flourished as a North Indian cultural and artistic hub, and the seat of power of Nawabs in the 18th and 19th centuries. It continues to be an important centre of governance, administration, education, commerce, aerospace, finance, pharmaceuticals, information technology, design, culture, tourism, music, and poetry. Lucknow, along with Agra and Varanasi, is in the Uttar P ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Delhi
Delhi, officially the National Capital Territory (NCT) of Delhi, is a city and a union territory of India containing New Delhi, the capital of India. Straddling the Yamuna river, but spread chiefly to the west, or beyond its Bank (geography), right bank, Delhi shares borders with the state of Uttar Pradesh in the east and with the state of Haryana in the remaining directions. Delhi became a union territory on 1 November 1956 and the NCT in 1995. The NCT covers an area of . According to the 2011 census, Delhi's city proper population was over 11 million, while the NCT's population was about 16.8 million. The topography of the medieval fort Purana Qila on the banks of the river Yamuna matches the literary description of the citadel Indraprastha in the Sanskrit epic ''Mahabharata''; however, excavations in the area have revealed no signs of an ancient built environment. From the early 13th century until the mid-19th century, Delhi was the capital of two major empires, ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |