NyQuil
Vicks NyQuil is a brand of over-the-counter medication manufactured by Procter & Gamble intended for the relief of various symptoms of the common cold. All medications within the NyQuil imprint contain sedating antihistamines; they are intended to be taken before sleep. Its daytime counterpart is antihistamine-free DayQuil, formulated to avoid drowsiness. NyQuil is also used as a sleep aid. NyQuil was first marketed in the United States in 1966. Products NyQuil Cold/Flu Multisymptom Relief The liquid version of NyQuil Cold/Flu Multi-symptom Relief, available in syrup and LiquidCap form. The recommended adult dose contains: * Acetaminophen (650 mg/30 mL) (pain reliever/ fever reducer) * Dextromethorphan (30 mg/30 mL) (cough suppressant) * Doxylamine succinate (12.5 mg/30 mL) (antihistamine/hypnotic) The LiquiCap capsule version has the following active ingredients per pill, half the recommended adult dose: * Acetaminophen (325 mg/pill ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Doxylamine Succinate
Doxylamine is an antihistamine medication used to treat insomnia and allergy, allergies, and—in combination with pyridoxine (vitamin B6, vitamin B6)—to treat morning sickness in pregnant women. It is available over-the-counter and is sold under such brand names as Equate or Unisom, among others; and it is used in nighttime cold medicines (e.g., NyQuil) and pain medications containing paracetamol (acetaminophen) or codeine to help with sleep. The medication is delivered chemically by the salt doxylamine succinate and is taken oral administration, by mouth. Doxylamine and other first-generation antihistamines are the most widely used sleep medications in the world. Typical side effects of doxylamine include dizziness, drowsiness, grogginess, and dry mouth, among others. As an antihistamine, doxylamine is an inverse agonist of the histamine H1 receptor, H1 receptor. As a first-generation antihistamine, it typically crosses the blood–brain barrier into the brain, thereby produc ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Vicks Brands
Vicks is an American brand of over-the-counter medications owned by the American companies Procter & Gamble and Kaz Incorporated. Vicks manufactures NyQuil and its sister medication, DayQuil as well as other medications in the "Quil" line. Vicks also produces the Formula 44 brand of cough medicines, cough drops, Vicks VapoRub, and a number of inhaled breathing treatments. For much of its history, Vicks products were manufactured by the family-owned company Richardson-Vicks, Inc., based in Greensboro, North Carolina. Richardson-Vicks, Inc., was eventually sold to Procter & Gamble in 1985. Procter & Gamble divested the Vicks VapoSteam U.S. liquid inhalant business and sold it to Helen of Troy in 2015. In German-speaking countries (apart from Switzerland), Vicks is known as ''Wick'' to avoid brand blundering, as "Vicks" when pronounced in German would sound similar to a vulgar word. History In 1890, pharmacist Lunsford Richardson of Selma, North Carolina, took over the retail d ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Vicks
Vicks is an American brand of over-the-counter medications owned by the American companies Procter & Gamble and Kaz Incorporated. Vicks manufactures NyQuil and its sister medication, DayQuil as well as other medications in the "Quil" line. Vicks also produces the Formula 44 brand of cough medicines, cough drops, Vicks VapoRub, and a number of inhaled breathing treatments. For much of its history, Vicks products were manufactured by the family-owned company Richardson-Vicks, Inc., based in Greensboro, North Carolina. Richardson-Vicks, Inc., was eventually sold to Procter & Gamble in 1985. Procter & Gamble divested the Vicks VapoSteam U.S. liquid inhalant business and sold it to Helen of Troy in 2015. In German-speaking countries (apart from Switzerland), Vicks is known as ''Wick'' to avoid brand blundering, as "Vicks" when pronounced in German would sound similar to a vulgar word. History In 1890, pharmacist Lunsford Richardson of Selma, North Carolina, took over the r ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Dextromethorphan
Dextromethorphan, sold under the brand name Robitussin among others, is a cough suppressant used in many cough and Common cold, cold medicines. In 2022, the US Food and Drug Administration (FDA) approved the combination dextromethorphan/bupropion to serve as a rapid-acting antidepressant in people with major depressive disorder. It is in the morphinan class of medications with sedative, dissociative, and stimulant properties (at lower doses). Dextromethorphan does not have a significant Affinity (pharmacology), affinity for the Μ-opioid receptor, mu-opioid receptor activity typical of morphinan compounds and exerts its therapeutic effects through several other receptors. In its pure form, dextromethorphan occurs as a white powder. When exceeding approved dosages, dextromethorphan acts as a dissociative, dissociative hallucinogen. It has multiple mechanism of action, mechanisms of action, including actions as a nonselective serotonin reuptake inhibitor and a sigma-1 receptor ag ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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DayQuil
Vicks DayQuil is an over-the-counter combination medication product used for the temporary relief of common cold and flu symptoms. DayQuil is available in several formulations. DayQuil was introduced in 1974 under the name "Vicks DayCare" and is currently advertised for daytime use because of its non-drowsy active ingredients. The brand name was reintroduced as " DayQuil" in 1992. DayQuil's nighttime counterpart, NyQuil, is also available for the relief of cold and flu symptoms during the night. These products are not intended to cure the common cold or the flu. Product selection Selecting a product should depend on the specific symptom presentation of the user. Products should be selected with active ingredients limited only to those symptoms, thereby reducing the risk of over treatment with medications that the user is not showing symptoms for. Additionally, careful note should be taken when purchasing multiple over-the-counter cold and flu medicines because many products may co ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Phenylephrine
Phenylephrine, sold under the brand names Neosynephrine and Sudafed PE among others, is a medication used as a decongestant for uncomplicated nasal congestion in the form of a nasal spray or oral tablet, to dilate the pupil, to increase blood pressure given intravenously in cases of low blood pressure, and to relieve hemorrhoids as a suppository. It can also be applied to the skin. Common side effects when taken by mouth or injected include nausea, vomiting, headache, and anxiety. Use on hemorrhoids is generally well tolerated. Severe side effects may include a slow heart rate, intestinal ischemia, chest pain, kidney failure, and tissue death at the site of injection. It is unclear whether its use during pregnancy and breastfeeding is safe. Phenylephrine is a selective α1-adrenergic receptor agonist with minimal to no β-adrenergic receptor agonist activity or induction of norepinephrine release. It causes constriction of both arteries and veins. Phenylephrine ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Combat Methamphetamine Epidemic Act Of 2005
The Combat Methamphetamine Epidemic Act of 2005 (CMEA) is federal legislation enacted in the United States on March 9, 2006, to regulate, among other things, retail over-the-counter sales of following products because of their use in the manufacture of illegal drugs: *ephedrine *pseudoephedrine *phenylpropanolamine (no longer OTC due to a proposed increased risk of stroke in younger women) Retail provisions of the CMEA include daily sales limits and 30-day purchase limits, placement of product out of direct customer access, sales logbooks, customer ID verification, employee training, and self-certification of regulated sellers. The CMEA is found as Title VII of the USA PATRIOT Improvement and Reauthorization Act of 2005 (H.R. 3199). The last provisions of the law took effect on 30 September 2006. Justification Ephedrine, pseudoephedrine, and phenylpropanolamine are precursor chemicals used in the illicit manufacture of methamphetamine or amphetamine. They are also common ingredie ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Sudafed
Pseudoephedrine, sold under the brand name Sudafed among others, is a sympathomimetic medication which is used as a decongestant to treat nasal congestion. It has also been used off-label for certain other indications, like treatment of low blood pressure. At higher doses, it may produce various additional effects including stimulant, appetite suppressant, and performance-enhancing effects. In relation to this, non-medical use of pseudoephedrine has been encountered. The medication is taken by mouth. Side effects of pseudoephedrine include insomnia, elevated heart rate, increased blood pressure, restlessness, dizziness, anxiety, and dry mouth, among others. Rarely, pseudoephedrine has been associated with serious cardiovascular complications like heart attack and hemorrhagic stroke. Some people may be more sensitive to its cardiovascular effects. Pseudoephedrine acts as a norepinephrine releasing agent, thereby indirectly activating adrenergic receptors. As such, it is an ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Chlorpheniramine
Chlorphenamine (CP, CPM), also known as chlorpheniramine, is an antihistamine used to treat the symptoms of allergic conditions such as allergic rhinitis (hay fever). It is taken orally (by mouth). The medication takes effect within two hours and lasts for about 4–6 hours. It is a first-generation antihistamine and works by blocking the histamine H1 receptor. Common side effects include sleepiness, restlessness, and weakness. Other side effects may include dry mouth and wheeziness. Chlorpheniramine was patented in 1948 and came into medical use in 1949. It is available as a generic medication and over the counter. In 2022, it was the 291st most commonly prescribed medication in the United States, with more than 400,000 prescriptions. Medical uses Combination products Chlorphenamine is often combined with phenylpropanolamine to form an allergy medication with both antihistamine and decongestant properties, although phenylpropanolamine was removed from the U.S. m ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Diphenhydramine
Diphenhydramine, sold under the brand name Benadryl among others, is an antihistamine and sedative. Although generally considered sedating, diphenhydramine can cause paradoxical central nervous system stimulation in some individuals, particularly at higher doses. This may manifest as agitation, anxiety, or restlessness rather than sedation. It is a H1 antagonist#First-generation (non-selective, classical), first-generation H1-antihistamine and it works by blocking certain effects of histamine, which produces its antihistamine and sedative effects. Diphenhydramine is also a potent anticholinergic. It is mainly used to treat allergy, allergies, insomnia, and symptoms of the common cold. It is also less commonly used for tremors in parkinsonism, and nausea. It is taken oral administration, by mouth, injection into a vein, injected into a vein, injection into a muscle, injected into a muscle, or topical medication, applied to the skin. Maximal effect is typically around two hours af ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Pseudoephedrine
Pseudoephedrine, sold under the brand name Sudafed among others, is a sympathomimetic medication which is used as a decongestant to treat nasal congestion. It has also been used off-label for certain other indications, like treatment of low blood pressure. At higher doses, it may produce various additional effects including stimulant, appetite suppressant, and performance-enhancing effects. In relation to this, non-medical use of pseudoephedrine has been encountered. The medication is taken by mouth. Side effects of pseudoephedrine include insomnia, elevated heart rate, increased blood pressure, restlessness, dizziness, anxiety, and dry mouth, among others. Rarely, pseudoephedrine has been associated with serious cardiovascular complications like heart attack and hemorrhagic stroke. Some people may be more sensitive to its cardiovascular effects. Pseudoephedrine acts as a norepinephrine releasing agent, thereby indirectly activating adrenergic receptors. As such, it ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |