Norbert Pardi
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Norbert Pardi
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Szolnok
Szolnok (; also known by #Name and etymology, alternative names) is the county seat of Jász-Nagykun-Szolnok county in central Hungary. A city with county rights, it is located on the banks of the Tisza river, in the heart of the Great Hungarian Plain, which has made it an important cultural and economic crossroads for centuries. Szolnok also has one of Hungary’s best water polo teams. Name and etymology Szolnok was named after the first steward of the city, Szolnok (ispán), Szaunik or Zounok. The town was first officially mentioned under the name Zounok in 1075. In the following centuries, it was recorded variously as Zounok, Saunic, Zounuc, and Zawnuch. The variety of spellings likely comes from phonetic discrepancies occurring when Hungarian sounds were recorded using the Latin alphabet. Another possibility revolves around speculation that the name Szaunik was not a personal name after all, but rather a title relating to the significant salt trade (salt, ) in the area. In m ...
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MRNA Vaccine
An mRNA vaccine is a type of vaccine that uses a copy of a molecule called messenger RNA (mRNA) to produce an immune response. The vaccine delivers molecules of antigen-encoding mRNA into cells, which use the designed mRNA as a blueprint to build foreign protein that would normally be produced by a pathogen (such as a virus) or by a cancer cell. These protein molecules stimulate an adaptive immune response that teaches the body to identify and destroy the corresponding pathogen or cancer cells. The mRNA is delivered by a co-formulation of the RNA encapsulated in lipid nanoparticles that protect the RNA strands and help their absorption into the cells. Reactogenicity, the tendency of a vaccine to produce adverse reactions, is similar to that of conventional non-RNA vaccines. People susceptible to an autoimmune response may have an adverse reaction to messenger RNA vaccines. The advantages of mRNA vaccines over traditional vaccines are ease of design, speed and lower cost ...
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Living People
Purpose: Because living persons may suffer personal harm from inappropriate information, we should watch their articles carefully. By adding an article to this category, it marks them with a notice about sources whenever someone tries to edit them, to remind them of WP:BLP (biographies of living persons) policy that these articles must maintain a neutral point of view, maintain factual accuracy, and be properly sourced. Recent changes to these articles are listed on Special:RecentChangesLinked/Living people. Organization: This category should not be sub-categorized. Entries are generally sorted by family name In many societies, a surname, family name, or last name is the mostly hereditary portion of one's personal name that indicates one's family. It is typically combined with a given name to form the full name of a person, although several give .... Maintenance: Individuals of advanced age (over 90), for whom there has been no new documentation in the last ten ...
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Drew Weissman
Drew Weissman (born September 7, 1959) is an American physician and immunologist known for his contributions to RNA biology. Weissman is the inaugural Roberts Family Professor in Vaccine Research, director of the Penn Institute for RNA Innovation, and professor of medicine at the Perelman School of Medicine at the University of Pennsylvania (Penn). Weissman's work underlies the development of mRNA vaccines, the best known of which are COVID-19 vaccine#RNA vaccines, those for COVID-19 produced by BioNTech/Pfizer and Moderna. With biochemist Katalin Karikó, Weissman received the 2023 Nobel Prize in Physiology or Medicine, Nobel Prize in Physiology or Medicine in 2023 "for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19". Weissman has been a recipient and co-recipient of numerous awards, also including the prestigious Lasker–DeBakey Clinical Medical Research Award. In 2022, he was elected to the N ...
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Katalin Karikó
Katalin "Kati" Karikó (, ; born 17 January 1955) is a Hungarian-American biochemist who specializes in ribonucleic acid (RNA)-mediated mechanisms, particularly in vitro-Transcription (biology), transcribed messenger RNA (mRNA) for protein replacement therapy. Karikó laid the scientific groundwork for mRNA vaccines, overcoming major obstacles and skepticism in the scientific community. Karikó received the 2023 Nobel Prize in Physiology or Medicine, Nobel Prize in Physiology or Medicine in 2023 for her work, along with American immunologist Drew Weissman. Karikó co-founded and was CEO of RNARx from 2006 to 2013. From 2013 to 2022, she was associated with BioNTech RNA Pharmaceuticals, first as a vice president and promoted to senior vice president in 2019. In 2022, she left BioNTech to devote more time to research. In 2021, she received an honorary doctorate from the University of Szeged in Hungary, where she has since become a professor. While Karikó has also been associated ...
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Nucleoside
Nucleosides are glycosylamines that can be thought of as nucleotides without a phosphate group. A nucleoside consists simply of a nucleobase (also termed a nitrogenous base) and a five-carbon sugar (ribose or 2'-deoxyribose) whereas a nucleotide is composed of a nucleobase, a five-carbon sugar, and one or more phosphate groups. In a nucleoside, the anomeric carbon is linked through a glycosidic bond to the N9 of a purine or the N1 of a pyrimidine. Nucleotides are the molecular building blocks of DNA and RNA. List of nucleosides and corresponding nucleobases ''This list does not include modified nucleobases and the corresponding nucleosides'' Each chemical has a short symbol, useful when the chemical family is clear from the context, and a longer symbol, if further disambiguation is needed. For example, long nucleobase sequences in genomes are usually described by CATG symbols, not Cyt-Ade-Thy-Gua (see '' Nucleic acid sequence § Notation''). Sources Nucleosides can ...
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Kisújszállás
Kisújszállás is a town in Jász-Nagykun-Szolnok county, in the Northern Great Plain region of central Hungary. Geography It covers an area of and has a population of 12,869 people (2002). Politics The current mayor of Kisújszállás is István Kecze (Fidesz-KDNP-Nagykun Civilian Circle). The local Municipal Assembly, elected at the 2019 local government elections, is made up of 11 members (1 Mayor, 8 Individual constituencies MEPs and 3 Compensation List MEPs) divided into this political parties and alliances: Notable inhabitants * Katalin Karikó, Hungarian-American Nobel Prize winner and inventor of the COVID mRNA vaccine * Norbert Pardi, Hungarian biochemist specializing in mRNA-mediated mechanisms Twin towns – sister cities Kisújszállás is twinned with: * Eberschwang, Austria (1992) * Pačir (Bačka Topola), Serbia (1996) * Săcele, Romania (1999) * Serne, Ukraine (2000) * Spišská Nová Ves Spišská Nová Ves (; ; ) is a town in the Košice ...
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Influenza
Influenza, commonly known as the flu, is an infectious disease caused by influenza viruses. Symptoms range from mild to severe and often include fever, runny nose, sore throat, muscle pain, headache, coughing, and fatigue. These symptoms begin one to four (typically two) days after exposure to the virus and last for about two to eight days. Diarrhea and vomiting can occur, particularly in children. Influenza may progress to pneumonia from the virus or a subsequent bacterial infection. Other complications include acute respiratory distress syndrome, meningitis, encephalitis, and worsening of pre-existing health problems such as asthma and cardiovascular disease. There are four types of influenza virus: types A, B, C, and D. Aquatic birds are the primary source of influenza A virus (IAV), which is also widespread in various mammals, including humans and pigs. Influenza B virus (IBV) and influenza C virus (ICV) primarily infect humans, and influenza D virus (IDV) i ...
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Perelman School Of Medicine
The Perelman School of Medicine (commonly known as Penn Med) is the medical school of the University of Pennsylvania, a private, Ivy League research university located in Philadelphia. Founded in 1765, the Perelman School of Medicine is the oldest medical school in the United States. Today, the Perelman School of Medicine is a major center of biomedical research and education with over 2,900 faculty members and nearly $1 billion in annual sponsored program awards. History 18th century The founding of a school of medicine was proposed by John Morgan, a graduate of the College of Philadelphia and the University of Edinburgh Medical School. After training in Edinburgh and other European cities, Morgan returned to Philadelphia in 1765. With fellow University of Edinburgh Medical School graduate William Shippen Jr., Morgan persuaded the college's trustees to found the first medical school in the original Thirteen Colonies. Shortly before the medical school's creation, Morgan d ...
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Duke Center, Pennsylvania
Otto Township is a township in McKean County, Pennsylvania, United States. The population was 1,518 at the time of the 2020 census. Geography According to the United States Census Bureau, the township has a total area of 34.8 square miles (90.1 km2), all land. Demographics As of the census of 2000, there were 1,738 people, 678 households, and 496 families residing in the township. The population density was . There were 742 housing units at an average density of 21.3/sq mi (8.2/km2). The racial makeup of the township was 98.62% White, 0.29% African American, 0.40% Native American, 0.23% Asian, 0.06% from other races, and 0.40% from two or more races. Hispanic or Latino of any race were 0.23% of the population. There were 678 households, out of which 32.6% had children under the age of 18 living with them, 58.7% were married couples living together, 9.4% had a female householder with no husband present, and 26.7% were non-families. 24.0% of all households were ...
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University Of Szeged
The University of Szeged () is a Public university, public research university in Szeged, Hungary. Established as the Jesuit Academy of Kolozsvár in present-day Cluj-Napoca in 1581, the institution was re-established as a university in 1872 by Emperor Franz Joseph I of Austria, Franz Joseph I. The university relocated to Szeged in 1921, making it one of the oldest research universities in Hungary. It went through numerous changes throughout the 20th century and was eventually divided into distinct independent universities. The current University of Szeged was formed in 2000 and is made up of twelve constituent Faculty (division), faculties and nineteen doctoral schools, which consist of a range of departments and research groups. Each faculty functions autonomously. In addition to these, the university also operates the Health Centre of the University of Szeged, an extensive teaching hospital responsible for Public healthcare, public regional Health care, healthcare, and three l ...
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European Society Of Clinical Microbiology And Infectious Diseases
The European Society of Clinical Microbiology and Infectious Diseases (ESCMID) is a non-profit international organization with headquarters in Basel, Switzerland. An important activity of the society is the organization of the annual scientific congress ESCMID Global (formerly known as ECCMID). The congress began as a biannual event, with about 1,500 participants at its inaugural occurrence in 1983. It became an annual event in 2000, and it has grown since then, now attracting over 16,000 participants annually. More than 5,000 scientific abstracts are submitted for inclusion each year by researchers from multiple countries. The most recent ESCMID Global was held in April 2024 in a hybrid format, both online and onsite, in Barcelona, Spain. Structure ESCMID is headquartered in Basel, Switzerland. The main governance organ is the executive committee (EC), which is elected by ESCMID members, and divided further into several subcommittees with specific functions (professional affa ...
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