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Nextflow
Nextflow is a scientific workflow system predominantly used for Bioinformatics, bioinformatic data analysis. It establishes standards for programmatically creating a series of dependent computational steps and facilitates their execution on various local and Cloud computing, cloud resources. Purpose Many scientific data analyses require a significant amount of sequential processing steps. Custom scripts may suffice when developing new methods or infrequently running particular analyses, but scale poorly to complex task successions or many samples. Scientific workflow systems like Nextflow allow formalizing an analysis as a data analysis pipeline. Pipelines, also known as workflows, specify the order and conditions of computing steps. They are accomplished by special purpose programs, so-called workflow executors, which ensure predictable and reproducible behavior in various computing environments. Workflow systems also provide built-in solutions to common challenges of wor ...
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Seqera Labs
Seqera Labs is a bioinformatics company developing technologies for data pipelines, founded in 2018 in Barcelona. It is a spin-off of the Centre for Genomic Regulation (CRG) founded by Evan Floden and Paolo di Tommaso and its services are largely related to the open-source software Nextflow, released in 2013. In 2022, the company raised 22 million euros in Series A funding. It has also received several grants from the Chan Zuckerberg Initiative The Chan Zuckerberg Initiative (CZI) is an organization established and owned by Facebook founder Mark Zuckerberg and his wife Priscilla Chan with an investment of 99 percent of the couple's wealth from their Facebook shares over their lifetim .... References {{Reflist External links Official website Bioinformatics companies Companies based in Barcelona Spanish companies established in 2018 ...
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Dataflow Programming
In computer programming, dataflow programming is a programming paradigm that models a program as a directed graph of the data flowing between operations, thus implementing dataflow principles and architecture. Dataflow programming languages share some features of functional languages, and were generally developed in order to bring some functional concepts to a language more suitable for numeric processing. Some authors use the term ''datastream'' instead of ''dataflow'' to avoid confusion with dataflow computing or dataflow architecture, based on an indeterministic machine paradigm. Dataflow programming was pioneered by Jack Dennis and his graduate students at MIT in the 1960s. Considerations Traditionally, a program is modelled as a series of operations happening in a specific order; this may be referred to as sequential, procedural, control flow (indicating that the program chooses a specific path), or imperative programming. The program focuses on commands, in line with the ...
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Scientific Workflow System
A scientific workflow system is a specialized form of a workflow management system designed specifically to compose and execute a series of computational or data manipulation steps, or workflow, in a scientific application. Scientific workflow systems are generally developed for use by scientists from different disciplines like astronomy, earth science, and bioinformatics. All such systems are based on an abstract representation of how a computation proceeds in the form of a directed graph, where each node represents a task to be executed and edges represent either data flow or execution dependencies between different tasks. Each system typically provides a visual front-end, allowing the user to build and modify complex applications with little or no programming expertise. Applications Distributed scientists can collaborate on conducting large scale scientific experiments and knowledge discovery applications using distributed systems of computing resources, data sets, and devices. ...
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Massive Parallel Sequencing
Massive parallel sequencing or massively parallel sequencing is any of several high-throughput approaches to DNA sequencing using the concept of massively parallel processing; it is also called next-generation sequencing (NGS) or second-generation sequencing. Some of these technologies emerged between 1993 and 1998 and have been commercially available since 2005. These technologies use miniaturized and parallelized platforms for sequencing of 1 million to 43 billion short reads (50 to 400 bases each) per instrument run. Many NGS platforms differ in engineering configurations and sequencing chemistry. They share the technical paradigm of massive parallel sequencing via spatially separated, clonally amplified DNA templates or single DNA molecules in a flow cell. This design is very different from that of Sanger sequencing—also known as capillary sequencing or first-generation sequencing—which is based on electrophoretic separation of chain-termination products produced in ind ...
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Apache License
The Apache License is a permissive free software license written by the Apache Software Foundation (ASF). It allows users to use the software for any purpose, to distribute it, to modify it, and to distribute modified versions of the software under the terms of the license, without concern for royalties. The ASF and its projects release their software products under the Apache License. The license is also used by many non-ASF projects. History Beginning in 1995, the Apache Group (later the Apache Software Foundation) released successive versions of the Apache HTTP Server. Its initial license was essentially the same as the original 4-clause BSD license, with only the names of the organizations changed, and with an additional clause forbidding derivative works from bearing the Apache name. In July 1999, the Berkeley Software Distribution accepted the argument put to it by the Free Software Foundation and retired their ''advertising clause'' (clause 3) to form the new 3-clau ...
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GNU General Public License
The GNU General Public Licenses (GNU GPL or simply GPL) are a series of widely used free software licenses, or ''copyleft'' licenses, that guarantee end users the freedom to run, study, share, or modify the software. The GPL was the first copyleft license available for general use. It was originally written by Richard Stallman, the founder of the Free Software Foundation (FSF), for the GNU Project. The license grants the recipients of a computer program the rights of the Free Software Definition. The licenses in the GPL series are all copyleft licenses, which means that any derivative work must be distributed under the same or equivalent license terms. The GPL is more restrictive than the GNU Lesser General Public License, and even more distinct from the more widely used permissive software licenses such as BSD, MIT, and Apache. Historically, the GPL license family has been one of the most popular software licenses in the free and open-source software (FOSS) domai ...
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GitLab
GitLab is a software forge primarily developed by GitLab Inc. It is available as a community edition and a commercial edition. History GitLab was created in 2011 by Ukrainian programmer Dmitriy Zaporozhets as a side project written in Ruby on Rails. Sytse Sijbrandij wanted to sell it as a service, which Zaporozhets agreed to. So the GitLab B.V. was founded in Utrecht in the Netherlands. Later Zaporozhets quit his job and started as CTO at GitLab. In 2015 GitLab became Member in the Y Combinator Y Combinator, LLC (YC) is an American technology startup accelerator and venture capital firm launched in March 2005 which has been used to launch more than 5,000 companies. The accelerator program started in Boston and Mountain View, Californi ... and collected US$1.5 million of seed funding. In September, Khosla Ventures invested an additional $4 million into the company. In September 2016 August Capital, Y Combinator and Khosla Ventures collected $20 million. GNOME has als ...
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Ruby (programming Language)
Ruby is a general-purpose programming language. It was designed with an emphasis on programming productivity and simplicity. In Ruby, everything is an object (computer science), object, including primitive data types. It was developed in the mid-1990s by Yukihiro Matsumoto, Yukihiro "Matz" Matsumoto in Japan. Ruby is interpreted language, interpreted, high-level programming language, high-level, and Dynamic typing, dynamically typed; its interpreter uses garbage collection (computer science), garbage collection and just-in-time compilation. It supports multiple programming paradigms, including procedural programming, procedural, object-oriented programming, object-oriented, and functional programming. According to the creator, Ruby was influenced by Perl, Smalltalk, Eiffel (programming language), Eiffel, Ada (programming language), Ada, BASIC, and Lisp (programming language), Lisp. History Early concept According to Matsumoto, Ruby was conceived in 1993. In a 1999 post to t ...
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University Of Tübingen
The University of Tübingen, officially the Eberhard Karl University of Tübingen (; ), is a public research university located in the city of Tübingen, Baden-Württemberg, Germany. The University of Tübingen is one of eleven German Excellence Universities. The University of Tübingen is especially known as a centre for the study of plant biology, medicine, law, archeology, ancient cultures, philosophy, theology, religious studies, humanities, and more recently as a center of excellence for artificial intelligence. The university's noted alumni and faculty include presidents, a pope, EU Commissioners, judges of the Federal Constitutional Court, and Johannes Kepler. The university is associated with eleven List of Nobel laureates, Nobel laureates, especially in the fields of medicine and chemistry. History The University of Tübingen was founded in 1477 by Count Eberhard I, Duke of Württemberg, Eberhard V (Eberhard im Bart, 1445–1496), later the first Duke of Württemberg ...
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GitHub
GitHub () is a Proprietary software, proprietary developer platform that allows developers to create, store, manage, and share their code. It uses Git to provide distributed version control and GitHub itself provides access control, bug tracking system, bug tracking, software feature requests, task management, continuous integration, and wikis for every project. Headquartered in California, GitHub, Inc. has been a subsidiary of Microsoft since 2018. It is commonly used to host open source software development projects. GitHub reported having over 100 million developers and more than 420 million Repository (version control), repositories, including at least 28 million public repositories. It is the world's largest source code host Over five billion developer contributions were made to more than 500 million open source projects in 2024. About Founding The development of the GitHub platform began on October 19, 2005. The site was launched in April 2008 by Tom ...
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DevOps
DevOps is the integration and automation of the software development and information technology operations. DevOps encompasses necessary tasks of software development and can lead to shortening development time and improving the development life cycle. According to Neal Ford, DevOps, particularly through continuous delivery, employs the "Bring the pain forward" principle, tackling tough tasks early, fostering automation and swift issue detection. Software programmers and architects should use fitness functions to keep their software in check. Although debated, DevOps is characterized by key principles: shared ownership, workflow automation, and rapid feedback. From an academic perspective, Len Bass, Ingo Weber, and Liming Zhu—three computer science researchers from the CSIRO and the Software Engineering Institute—suggested defining DevOps as "a set of practices intended to reduce the time between committing a change to a system and the change being placed into normal produ ...
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