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Mucinous Adenocarcinoma
A mucinous neoplasm (also called colloid neoplasm) is an abnormal and excessive growth of tissue (neoplasia) with associated mucin (a fluid that sometimes resembles thyroid colloid). It arises from epithelial cells that line certain internal organs and skin, and produce mucin (the main component of mucus). A malignant mucinous neoplasm is called a mucinous carcinoma. For example, for ovarian mucinous tumors, approximately 75% are benign, 10% are borderline and 15% are malignant. Mucinous carcinoma Over 40 percent of all mucinous carcinomas are colorectal. When found within the skin, mucinous carcinoma is commonly a round, elevated, reddish, and sometimes ulcerated mass, usually located on the head and neck. File:Histopathology of mucinous invasive ductal carcinoma of the breast.jpg, Mucinous carcinoma of the breast: Gross pathology (upper left) of mucinous carcinoma shows gelatinous areas. Histopathology shows clusters or nests of tumor cells floating in pools of extracellular m ...
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Micrograph
A micrograph is an image, captured photographically or digitally, taken through a microscope or similar device to show a magnify, magnified image of an object. This is opposed to a macrograph or photomacrograph, an image which is also taken on a microscope but is only slightly magnified, usually less than 10 times. Micrography is the practice or art of using microscopes to make photographs. A photographic micrograph is a photomicrograph, and one taken with an electron microscope is an electron micrograph. A micrograph contains extensive details of microstructure. A wealth of information can be obtained from a simple micrograph like behavior of the material under different conditions, the phases found in the system, failure analysis, grain size estimation, elemental analysis and so on. Micrographs are widely used in all fields of microscopy. Types Photomicrograph A light micrograph or photomicrograph is a micrograph prepared using an optical microscope, a process referred to ...
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Malignant
Malignancy () is the tendency of a medical condition to become progressively worse; the term is most familiar as a characterization of cancer. A ''malignant'' tumor contrasts with a non-cancerous benign tumor, ''benign'' tumor in that a malignancy is not self-limited in its growth, is capable of invading into adjacent tissues, and may be capable of spreading to distant tissues. A benign tumor has none of those properties, but may still be harmful to health. The term benign in more general medical use characterizes a condition or growth that is not cancerous, i.e. does not spread to other parts of the body or invade nearby tissue. Sometimes the term is used to suggest that a condition is not dangerous or serious. Malignancy in cancers is characterized by anaplasia, invasiveness, and metastasis. Malignant tumors are also characterized by genome instability, so that cancers, as assessed by whole genome sequencing, frequently have between 10,000 and 100,000 mutations in their ent ...
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List Of Cutaneous Conditions
Many skin conditions affect the human integumentary system—the organ system covering the entire surface of the Human body, body and composed of Human skin, skin, hair, Nail (anatomy), nails, and related muscle and glands. The major function of this system is as a barrier against the external environment. The skin weighs an average of four kilograms, covers an area of two square metres, and is made of three distinct layers: the epidermis (skin), epidermis, dermis, and subcutaneous tissue. The two main types of human skin are: glabrous skin, the hairless skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin.Burns, Tony; ''et al''. (2006) ''Rook's Textbook of Dermatology CD-ROM''. Wiley-Blackwell. . Within the latter type, the hairs occur in structures called pilosebaceous units, each with hair follicle, sebaceous gland, and associated arrector pili muscle. Embryology, In the embryo, the epidermis, hair, and glands form from the ectod ...
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Primary Cutaneous Adenoid Cystic Carcinoma
Primary cutaneous adenoid cystic carcinoma is a cutaneous condition characterized by a tumor that usually presents on the chest, scalp, or vulva of middle- to older-aged persons. Primary cutaneous adenoid cystic carcinomas have been misinterpreted as metastatic lesions. It was characterized in 1975. Primary cutaneous adenoid cystic carcinoma is a hard, slowly expanding, ill-defined tumor causing discomfort, itching, and secondary baldness, or may be asymptomatic. Primary cutaneous adenoid cystic carcinoma is a rare condition that is believed to be caused by somatic mutations. Primary cutaneous adenoid cystic carcinoma diagnosis relies on tumor histology features, but a comprehensive clinical and radiographic examination is necessary to identify other primary disease indications, especially in salivary glands. Primary cutaneous adenoid cystic carcinoma therapy involves broad surgical excision with a 2 cm safety margin, and lymphadenectomy if nodal involvement is suspected. Si ...
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Microcystic Adnexal Carcinoma
Microcystic adnexal carcinoma (MAC) is a rare sweat gland cancer, which often appears as a yellow spot or bump in the skin. It usually occurs in the neck or head, although cases have been documented in other areas of the body. Most diagnosis occur past the age of 50. Although considered an invasive cancer, metastasis rarely occurs. If the tumor spreads, it can grow and invade fat, muscles, and other types of tissue. Main treatments are wide local excision or Mohs micrographic surgery, which ensures that most, if not all, cancer cells are removed surgically. Presentation MACs usually present as a smooth, flesh or yellow colored, slow-growing nodule or bump somewhere on the face or neck with typical development being 3–5 years. The most common location is the mouth (occurring in 74% of cases), however cases have been documented on the scalp, tongue, trunk, upper extremities, and genitals. Patients are more likely to be white, female, and middle aged or elderly, although cases have ...
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Eccrine Carcinoma
Eccrine carcinoma is a rare skin condition characterized by a plaque or nodule on the scalp, trunk, or extremities. It originates from the eccrine sweat glands of the skin, accounting for less than 0.01% of diagnosed cutaneous malignancies. Eccrine carcinoma tumors are locally aggressive, with a high rate of recurrence. Lack of reliable immunohistochemical markers and similarity to other common tumors has made identification of eccrine carcinoma difficult. Most eccrine carcinomas which have not spread can be cured by wide local excision. However, metastatic disease carries a poor prognosis. Symptoms Eccrine carcinoma results in brown, bluish, erythematous skin lesions across the body. Common regions where lesions are found are in the lower extremities (35%), head and neck (24%), and upper extremities (14%). Complications Metastases and/or antagonistic side effects can occur after surgical excision of tumors. Types Eccrine carcinomas include porocarcinoma, hidradenocarci ...
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Mucinous Carcinoma Of The Breast
Mucinous carcinoma of the breast is a form of mucinous carcinoma and a breast cancer type. It is a rare form of breast cancer that accounts for 2% of breast carcinomas and most commonly occurs in postmenopausal women over 70 years old. Rare cases of this carcinoma have been diagnosed in men (see male breast cancer). Diagnosis Mucinous carcinoma of the breast grows slowly and can become a large size before diagnosis. Late diagnosis is also due to how the mucinous contents of the tumor don't feel solid. Mammography, ultrasound, MRI, and tissue biopsy are often employed to diagnose mucinous breast carcinoma. Prognosis With a 5-year survival rate of 81% to 94%, mucinous breast cancer tends to have a good prognosis. There is also a low incidence of metastasis Metastasis is a pathogenic agent's spreading from an initial or primary site to a different or secondary site within the host's body; the term is typically used when referring to metastasis by a cancerous tumor. The ...
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Benign
Malignancy () is the tendency of a medical condition to become progressively worse; the term is most familiar as a characterization of cancer. A ''malignant'' tumor contrasts with a non-cancerous benign tumor, ''benign'' tumor in that a malignancy is not self-limited in its growth, is capable of invading into adjacent tissues, and may be capable of spreading to distant tissues. A benign tumor has none of those properties, but may still be harmful to health. The term benign in more general medical use characterizes a condition or growth that is not cancerous, i.e. does not spread to other parts of the body or invade nearby tissue. Sometimes the term is used to suggest that a condition is not dangerous or serious. Malignancy in cancers is characterized by anaplasia, invasiveness, and metastasis. Malignant tumors are also characterized by genome instability, so that cancers, as assessed by whole genome sequencing, frequently have between 10,000 and 100,000 mutations in their ent ...
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Ovarian Mucinous Tumor
Mucinous tumors are a type of ovarian tumor. They are typically large. They are part of the surface epithelial-stromal tumor group of ovarian neoplasms, and account for approximately 36% of all ovarian tumors. Approximately 75% are benign, 10% are borderline and 15% are malignant. Rarely, the tumor is seen bilaterally; approximately 5% of primary mucinous tumors are bilateral. ''Benign'' mucinous tumors are typically multilocular (have several lobes), and the cysts have a smooth lining of epithelium that resembles endocervical epithelial cells with small numbers of gastrointestinal-type epithelial cells. ''Borderline'' and ''malignant'' mucinous tumors often have papillae and solid areas. There may also be hemorrhage and necrosis Necrosis () is a form of cell injury which results in the premature death of cells in living tissue by autolysis. The term "necrosis" came about in the mid-19th century and is commonly attributed to German pathologist Rudolf Virchow, who i ...
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Mucus
Mucus (, ) is a slippery aqueous secretion produced by, and covering, mucous membranes. It is typically produced from cells found in mucous glands, although it may also originate from mixed glands, which contain both Serous fluid, serous and mucous cells. It is a viscous colloid containing inorganic ions, inorganic salts, antimicrobial enzymes (such as lysozymes), Antibody, immunoglobulins (especially Immunoglobulin A, IgA), and glycoproteins such as lactoferrin and mucins, which are produced by goblet cells in the mucous membranes and submucosal glands. Mucus covers the Epithelium, epithelial cells that interact with outside environment, serves to protect the linings of the respiratory system, respiratory, Digestion#Digestive system, digestive, and Genitourinary system, urogenital systems, and structures in the Visual system, visual and auditory systems from pathogenic Fungus, fungi, bacteria and viruses. Most of the mucus in the body is produced in the gastrointestinal tract. ...
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Colon (anatomy)
The large intestine, also known as the large bowel, is the last part of the gastrointestinal tract and of the digestive system in tetrapods. Water is absorbed here and the remaining waste material is stored in the rectum as feces before being removed by defecation. The colon (progressing from the ascending colon to the transverse, the descending and finally the sigmoid colon) is the longest portion of the large intestine, and the terms "large intestine" and "colon" are often used interchangeably, but most sources define the large intestine as the combination of the cecum, colon, rectum, and anal canal. Some other sources exclude the anal canal. In humans, the large intestine begins in the right iliac region of the pelvis, just at or below the waist, where it is joined to the end of the small intestine at the cecum, via the ileocecal valve. It then continues as the colon ascending the abdomen, across the width of the abdominal cavity as the transverse colon, and then desce ...
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Internal Organs
In a multicellular organism, an organ is a collection of tissues joined in a structural unit to serve a common function. In the hierarchy of life, an organ lies between tissue and an organ system. Tissues are formed from same type cells to act together in a function. Tissues of different types combine to form an organ which has a specific function. The intestinal wall for example is formed by epithelial tissue and smooth muscle tissue. Two or more organs working together in the execution of a specific body function form an organ system, also called a biological system or body system. An organ's tissues can be broadly categorized as parenchyma, the functional tissue, and stroma, the structural tissue with supportive, connective, or ancillary functions. For example, the gland's tissue that makes the hormones is the parenchyma, whereas the stroma includes the nerves that innervate the parenchyma, the blood vessels that oxygenate and nourish it and carry away its metabolic wa ...
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