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A mucinous neoplasm (also called colloid neoplasm) is an abnormal and excessive growth of tissue (
neoplasia A neoplasm () is a type of abnormal and excessive growth of tissue. The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that of the normal surrounding tissue, and persists ...
) with associated
mucin Mucins () are a family of high molecular weight, heavily glycosylated proteins ( glycoconjugates) produced by epithelial tissues in most animals. Mucins' key characteristic is their ability to form gels; therefore they are a key component in ...
(a fluid that sometimes resembles
thyroid colloid The thyroid, or thyroid gland, is an endocrine gland in vertebrates. In humans, it is a butterfly-shaped gland located in the neck below the Adam's apple. It consists of two connected lobes. The lower two thirds of the lobes are connected by ...
). It arises from
epithelial cell Epithelium or epithelial tissue is a thin, continuous, protective layer of Cell (biology), cells with little extracellular matrix. An example is the epidermis, the outermost layer of the skin. Epithelial (Mesothelium, mesothelial) tissues line ...
s that line certain
internal organs In a multicellular organism, an organ is a collection of tissues joined in a structural unit to serve a common function. In the hierarchy of life, an organ lies between tissue and an organ system. Tissues are formed from same type cells to a ...
and skin, and produce mucin (the main component of
mucus Mucus (, ) is a slippery aqueous secretion produced by, and covering, mucous membranes. It is typically produced from cells found in mucous glands, although it may also originate from mixed glands, which contain both Serous fluid, serous and muc ...
). A
malignant Malignancy () is the tendency of a medical condition to become progressively worse; the term is most familiar as a characterization of cancer. A ''malignant'' tumor contrasts with a non-cancerous benign tumor, ''benign'' tumor in that a malig ...
mucinous neoplasm is called a mucinous carcinoma. For example, for
ovarian mucinous tumor Mucinous tumors are a type of ovarian tumor. They are typically large. They are part of the surface epithelial-stromal tumor group of ovarian neoplasms, and account for approximately 36% of all ovarian tumors. Approximately 75% are benign, 10% ...
s, approximately 75% are
benign Malignancy () is the tendency of a medical condition to become progressively worse; the term is most familiar as a characterization of cancer. A ''malignant'' tumor contrasts with a non-cancerous benign tumor, ''benign'' tumor in that a malig ...
, 10% are borderline and 15% are malignant.


Mucinous carcinoma

Over 40 percent of all mucinous carcinomas are colorectal. When found within the skin, mucinous carcinoma is commonly a round, elevated, reddish, and sometimes ulcerated mass, usually located on the head and neck. File:Histopathology of mucinous invasive ductal carcinoma of the breast.jpg,
Mucinous carcinoma of the breast Mucinous carcinoma of the breast is a form of mucinous carcinoma and a breast cancer type. It is a rare form of breast cancer that accounts for 2% of breast carcinomas and most commonly occurs in postmenopausal women over 70 years old. Rare case ...
: Gross pathology (upper left) of mucinous carcinoma shows gelatinous areas. Histopathology shows clusters or nests of tumor cells floating in pools of extracellular mucin. Topic Completed: 23 February 2021. Minor changes: 23 February 2021


See also

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Eccrine carcinoma Eccrine carcinoma is a rare skin condition characterized by a plaque or nodule on the scalp, trunk, or extremities. It originates from the eccrine sweat glands of the skin, accounting for less than 0.01% of diagnosed cutaneous malignancies. Eccri ...
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Microcystic adnexal carcinoma Microcystic adnexal carcinoma (MAC) is a rare sweat gland cancer, which often appears as a yellow spot or bump in the skin. It usually occurs in the neck or head, although cases have been documented in other areas of the body. Most diagnosis occur ...
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Primary cutaneous adenoid cystic carcinoma Primary cutaneous adenoid cystic carcinoma is a cutaneous condition characterized by a tumor that usually presents on the chest, scalp, or vulva of middle- to older-aged persons. Primary cutaneous adenoid cystic carcinomas have been misinterpreted ...
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List of cutaneous conditions Many skin conditions affect the human integumentary system—the organ system covering the entire surface of the Human body, body and composed of Human skin, skin, hair, Nail (anatomy), nails, and related muscle and glands. The major function o ...
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Pseudomyxoma peritonei Pseudomyxoma peritonei (PMP) is a clinical condition caused by cancerous cells (mucinous adenocarcinoma) that produce abundant mucin or gelatinous ascites. The tumors cause fibrosis of tissues and impede digestion or organ function, and if left unt ...


Notes


References

* {{NCI-cancer-dict
Mucinous carcinoma
entry in the public domain NCI Dictionary of Cancer Terms Epidermal nevi, neoplasms, and cysts