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MotB
Motility protein B also known as MotB is a bacterial protein that is encoded by the ''motB'' gene. It's a component of the flagellar motor. More specifically, MotA and MotB makes the stator of a flagellum and surround the rotor as a ring of about 8-10 particles. MotA and MotB are integral membrane proteins. While both MotA and MotB surround the MS ring, MotB also anchors MotA to cell wall peptidoglycan. These two proteins form pores that harvest energy for flagellar mechanical movement by proton motive force (PMF) across the membrane. Cellular metabolic processes such as the electron transport chain move protons outside the cell, creating more protons and more positive charge in the extracellular space. When the protons flow back into the cell through MotA and MotB along concentration and charge gradients, they release energy that is used for flagellar rotation. The speed of the flagellar motor is dependent on the magnitude of the PMF acting on MotA and MotB. See also * Mot ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
PomB
PomB is a protein that is part of the stator in Na+ driven bacterial flagella. Na influx to torque generation in the polar flagellar motor of Vibrio alginolyticus. The stator complex is fixed-anchored around the rotor through a putative peptidoglycan-binding (PGB) domain in the periplasmic region of PomB. See also *MotB - MotA and MotB make the stator * MotA - MotA and MotB make the stator *PomA - protein that is part of the stator in Na+ *Integral membrane protein a type of membrane protein *Archaellum *Cilium *Ciliopathy *Rotating locomotion in living systems *Undulipodium An undulipodium or undulopodium (Greek: "swinging foot"; plural undulipodia) is a motile filamentous extension of eukaryotic cells, composed of a membrane protrusion held by a cytoskeletal structure called the axoneme. It is divided into cilia and ... References Motor proteins Bacterial proteins {{protein-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metabolic reactions, DNA replication, Cell signaling, responding to stimuli, providing Cytoskeleton, structure to cells and Fibrous protein, organisms, and Intracellular transport, transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the Nucleic acid sequence, nucleotide sequence of their genes, and which usually results in protein folding into a specific Protein structure, 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called pep ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene
In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protein-coding genes and non-coding genes. During gene expression (the synthesis of Gene product, RNA or protein from a gene), DNA is first transcription (biology), copied into RNA. RNA can be non-coding RNA, directly functional or be the intermediate protein biosynthesis, template for the synthesis of a protein. The transmission of genes to an organism's offspring, is the basis of the inheritance of phenotypic traits from one generation to the next. These genes make up different DNA sequences, together called a genotype, that is specific to every given individual, within the gene pool of the population (biology), population of a given species. The genotype, along with environmental and developmental factors, ultimately determines the phenotype ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Flagellum
A flagellum (; : flagella) (Latin for 'whip' or 'scourge') is a hair-like appendage that protrudes from certain plant and animal sperm cells, from fungal spores ( zoospores), and from a wide range of microorganisms to provide motility. Many protists with flagella are known as flagellates. A microorganism may have from one to many flagella. A gram-negative bacterium '' Helicobacter pylori'', for example, uses its flagella to propel itself through the stomach to reach the mucous lining where it may colonise the epithelium and potentially cause gastritis, and ulcers – a risk factor for stomach cancer. In some swarming bacteria, the flagellum can also function as a sensory organelle, being sensitive to wetness outside the cell. Across the three domains of Bacteria, Archaea, and Eukaryota, the flagellum has a different structure, protein composition, and mechanism of propulsion but shares the same function of providing motility. The Latin word means " whip" to describe its ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stator
The stator is the stationary part of a rotary system, found in electric generators, electric motors, sirens, mud motors, or biological rotors (such as bacterial flagella or ATP synthase). Energy flows through a stator to or from the rotating component of the system, the rotor. In an electric motor, the stator provides a magnetic field that drives the rotating armature; in a generator, the stator converts the rotating magnetic field to electric current. In fluid powered devices, the stator guides the flow of fluid to or from the rotating part of the system. Design Motor stators are made either from iron/steel or from a printed circuit board (PCB). Originally applied to low-power applications, PCB stators can be lighter, smaller, and less noisy. One design embeds thin copper traces in the PCB stator that serve as the windings. The traces are interleaved with epoxy-glass laminates, that insulate each coil from its neighbors. An air core replaces the traditional iron core ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Integral Membrane Protein
An integral, or intrinsic, membrane protein (IMP) is a type of membrane protein that is permanently attached to the biological membrane. All transmembrane proteins can be classified as IMPs, but not all IMPs are transmembrane proteins. IMPs comprise a significant fraction of the proteins encoded in an organism's genome. Proteins that cross the membrane are surrounded by annular lipids, which are defined as lipids that are in direct contact with a membrane protein. Such proteins can only be separated from the membranes by using detergents, nonpolar solvents, or sometimes denaturing agents. Proteins that adhere only temporarily to cellular membranes are known as peripheral membrane proteins. These proteins can either associate with integral membrane proteins, or independently insert in the lipid bilayer in several ways. Structure Three-dimensional structures of ~160 different integral membrane proteins have been determined at atomic resolution by X-ray crystallography or nucle ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
PomA
Poma, incorporated as Pomagalski S.A., and sometimes referred to as the Poma Group, is a French company which manufactures cable-driven lift systems, including fixed and detachable chairlifts, gondola lifts, funiculars, aerial tramways, people movers, and surface lifts. Poma has installed about 7800 devices for 750 customers worldwide. Poma's only major competitor is the Doppelmayr Garaventa Group which is based in Austria and Switzerland. Italy's Leitner Ropeways was historically another competitor until 2000 when Poma became part of Seeber Group (now HTI). Poma and Leitner remain independent, but formed a strategic partnership which includes the combined purchase of raw materials and the formation of Leitner-Poma as a joint venture in North America. The majority of Poma's lifts are used in ski areas in Europe, Asia, and North America (as Leitner-Poma), they have also installed installations in amusement parks, scenic locations, and industrial transportation applic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Integral Membrane Protein
An integral, or intrinsic, membrane protein (IMP) is a type of membrane protein that is permanently attached to the biological membrane. All transmembrane proteins can be classified as IMPs, but not all IMPs are transmembrane proteins. IMPs comprise a significant fraction of the proteins encoded in an organism's genome. Proteins that cross the membrane are surrounded by annular lipids, which are defined as lipids that are in direct contact with a membrane protein. Such proteins can only be separated from the membranes by using detergents, nonpolar solvents, or sometimes denaturing agents. Proteins that adhere only temporarily to cellular membranes are known as peripheral membrane proteins. These proteins can either associate with integral membrane proteins, or independently insert in the lipid bilayer in several ways. Structure Three-dimensional structures of ~160 different integral membrane proteins have been determined at atomic resolution by X-ray crystallography or nucle ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Archaellum
The archaellum (: archaella; formerly archaeal flagellum) is a unique structure on the cell surface of many archaea that allows for swimming motility. The archaellum consists of a rigid helix, helical filament that is attached to the cell membrane by a molecular motor. This molecular motorcomposed of cytosolic, membrane, and pseudo-periplasmic proteinsis responsible for the assembly of the filament and, once assembled, for its rotation. The rotation of the filament propels archaeal cells in liquid medium, in a manner similar to the propeller of a boat. The bacterial analog of the archaellum is the flagellum, which is also responsible for their swimming motility and can also be compared to a rotating corkscrew. Although the movement of archaella and flagella is sometimes described as "whip-like", this is incorrect, as only Cilium, cilia from Eukaryotes move in this manner. Indeed, even "wiktionary:flagellum, flagellum" (word derived from Latin meaning "whip") is a misnomer, as bac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cilium
The cilium (: cilia; ; in Medieval Latin and in anatomy, ''cilium'') is a short hair-like membrane protrusion from many types of eukaryotic cell. (Cilia are absent in bacteria and archaea.) The cilium has the shape of a slender threadlike projection that extends from the surface of the much larger cell body. Eukaryotic flagella found on sperm cells and many protozoans have a similar structure to motile cilia that enables swimming through liquids; they are longer than cilia and have a different undulating motion. There are two major classes of cilia: ''motile'' and ''non-motile'' cilia, each with two subtypes, giving four types in all. A cell will typically have one primary cilium or many motile cilia. The structure of the cilium core, called the axoneme, determines the cilium class. Most motile cilia have a central pair of single microtubules surrounded by nine pairs of double microtubules called a 9+2 axoneme. Most non-motile cilia have a 9+0 axoneme that lacks the centr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ciliopathy
Ciliopathies are a group of genetically diverse disorders caused by defects in the structure or function of the primary cilium, a highly specialized and evolutionarily conserved organelle found in nearly all eukaryotic cells. The primary cilium plays a central role in regulating signal transduction and making it essential for numerous developmental and physiological processes. Because of the widespread presence of primary cilia in different tissues, dysfunction can lead to a broad spectrum of clinical features. Syndromic ciliopathies, such as Bardet-Biedl syndrome (BBS), typically involve multiple organ systems, including the retina, kidneys, central nervous system, and skeletal system These manifestations highlight the importance of cilia in embryonic development, sensory perception, and tissue homeostasis. The genetic basis of ciliopathies is complex, with significant allelic heterogeneity and pleiotropy, meaning the same gene may cause different disorders, while diff ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
