Minoru Shirota
was a Japanese microbiologist. In the 1930 Shirota identified a strain of lactic acid bacteria that is part of normal gut flora that he originally called ''Lactobacillus casei Shirota,'' which appeared to help contain the growth of harmful bacteria in the gut. The strain was later reclassified as ''Lactobacillus paracasei Shirota''. Lay summary: He founded the company Yakult Honsha in 1935 to sell beverages containing the strain branded Yakult. He died in Tokyo Tokyo, officially the Tokyo Metropolis, is the capital of Japan, capital and List of cities in Japan, most populous city in Japan. With a population of over 14 million in the city proper in 2023, it is List of largest cities, one of the most ..., Japan in 1982. References {{DEFAULTSORT:Shirota, Minoru 1899 births 1982 deaths Japanese military doctors Japanese microbiologists People from Iida, Nagano Scientists from Nagano Prefecture Japanese inventors ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Iida, Nagano
is a Cities of Japan, city in Nagano Prefecture, Japan. , Iida had an estimated population of 101,536, and a population density of 154 persons per km2. The total area of the city is . Iida is an , a municipalities of Japan, municipality designated by the Japanese government to be a model for making large cuts in greenhouse gas emissions towards a low-carbon society. Geography Iida is the southernmost city of Nagano Prefecture. Mount Hijiri at is the highest elevation in the city. Iida lies 90 minutes northeast of the major city of Nagoya by automobile via the Chūō Expressway. The same expressway also provides access to Tokyo, about four hours to the east. The nearest large metropolis to Iida is Nagoya, which is easily accessible by bus (about 2 hours). The larger cities of Matsumoto and Nagano in central and northern Nagano Prefecture are also accessible by bus and train. There is also a bus service to Shinjuku, Tokyo, which takes about four hours. Surrounding municipalities ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Tokyo
Tokyo, officially the Tokyo Metropolis, is the capital of Japan, capital and List of cities in Japan, most populous city in Japan. With a population of over 14 million in the city proper in 2023, it is List of largest cities, one of the most populous urban areas in the world. The Greater Tokyo Area, which includes Tokyo and parts of six neighboring Prefectures of Japan, prefectures, is the most populous metropolitan area in the world, with 41 million residents . Lying at the head of Tokyo Bay, Tokyo is part of the Kantō region, on the central coast of Honshu, Japan's largest island. It is Japan's economic center and the seat of the Government of Japan, Japanese government and the Emperor of Japan. The Tokyo Metropolitan Government administers Tokyo's central Special wards of Tokyo, 23 special wards, which formerly made up Tokyo City; various commuter towns and suburbs in Western Tokyo, its western area; and two outlying island chains, the Tokyo Islands. Although most of the w ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Yakult
is a Japanese sweetened probiotic milk beverage fermented with the bacteria strain '' Lacticaseibacillus casei'' Shirota. It is sold by Yakult Honsha based in Tokyo. The name "Yakult" was coined from ''jahurto'', an Esperanto word meaning "yogurt". Ingredients Yakult's ingredients are water, skimmed milk, glucose-fructose syrup, sucrose, natural flavours (citrus), and live ''Lacticaseibacillus casei'' Shirota bacteria. The strain was originally classified as being ''Lactobacillus casei''. Yakult is prepared by adding glucose to skimmed milk and heating the mixture at 90 to 95 °C for about 30 minutes. After letting it cool down to 45 °C, the mixture is inoculated with the lactobacillus and incubated for 6 to 7 days at 37 to 38 °C. After fermentation, water, sugar, gums, and lactic acid are added. Health claims In 2006, a panel appointed by the Netherlands Nutrition Center (''Voedingscentrum'') to evaluate a marketing request by Yakult found sufficient ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Lactic Acid Bacteria
Lactobacillales are an order of gram-positive, low-GC, acid-tolerant, generally nonsporulating, nonrespiring, either rod-shaped (bacilli) or spherical ( cocci) bacteria that share common metabolic and physiological characteristics. These bacteria, usually found in decomposing plants and milk products, produce lactic acid as the major metabolic end product of carbohydrate fermentation, giving them the common name lactic acid bacteria (LAB). Production of lactic acid has linked LAB with food fermentations, as acidification inhibits the growth of spoilage agents. Proteinaceous bacteriocins are produced by several LAB strains and provide an additional hurdle for spoilage and pathogenic microorganisms. Furthermore, lactic acid and other metabolic products contribute to the organoleptic and textural profile of a food item. The industrial importance of the LAB is further evidenced by their generally recognized as safe (GRAS) status, due to their ubiquitous appearance in food and the ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Gut Flora
Gut microbiota, gut microbiome, or gut flora are the microorganisms, including bacteria, archaea, fungi, and viruses, that live in the digestive tracts of animals. The gastrointestinal metagenome is the aggregate of all the genomes of the gut microbiota. The gut is the main location of the human microbiome. The gut microbiota has broad impacts, including effects on colonization, resistance to pathogens, maintaining the intestinal epithelium, metabolizing dietary and pharmaceutical compounds, controlling immune function, and even behavior through the gut–brain axis. The microbial composition of the gut microbiota varies across regions of the digestive tract. The colon contains the highest microbial density of any human-associated microbial community studied so far, representing between 300 and 1000 different species. Bacteria are the largest and to date, best studied component and 99% of gut bacteria come from about 30 or 40 species. About 55% of the dry mass of feces ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Lactobacillus Casei
''Lacticaseibacillus casei'' is an organism that belongs to the largest genus in the family ''Lactobacillaceae'', a lactic acid bacteria (LAB), that was previously classified as ''Lactobacillus casei''. This bacteria has been identified as facultatively anaerobic or microaerophilic, acid-tolerant, non-spore-forming bacteria. This species is a non-sporing, rod-shaped, gram positive microorganism that can be found within the reproductive and digestive tract of the human body. Since ''L. casei'' can survive in a variety of environmental habitats, it has and continues to be extensively studied by health scientists. Commercially, ''L. casei'' is used in fermenting dairy products and its application as a probiotic. In bacteraemia, it is regarded to be similar in pathogenicity to Lactobacillus and associated with infective endocarditis. Taxonomy The taxonomy of the ''L. casei'' group has been debated for several years because researchers struggled to differentiate between the st ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Lactobacillus Paracasei
''Lacticaseibacillus paracasei ''(commonly abbreviated as ''Lc. paracasei'') is a gram-positive, homofermentative species of lactic acid bacteria that are commonly used in dairy product fermentation and as probiotic cultures. ''Lc. paracasei'' is a bacterium that operates by commensalism. It is commonly found in many human habitats such as human intestinal tracts and mouths as well as sewages, silages, and previously mentioned dairy products. The name includes morphology, a rod-shaped (bacillus shape) bacterium with a width of 2.0 to 4.0μm and length of 0.8 to 1.0μm. Strains of ''L. paracasei'' have been isolated from a variety of environments including dairy products, plants or plant fermentations, and from the human and animal gastrointestinal tracts. A protracted refrigeration period before in vitro gastrointestinal transit (GIT) did not affect or influenced very weakly cell resistance. ''Lacticaseibacillus paracasei'' is genotypically and phenotypically closely related fr ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Yakult Honsha
is a Japanese company founded in 1955 to sell its flagship product, Yakult—a beverage made using industrial lactic milk, a bacterial strain discovered by Minoru Shirota in the 1920s. Yakult Honsha is a multinational corporation that sells various other products and owns the Tokyo Yakult Swallows baseball team, in addition to the Roaring Raymonds. The company regularly promotes what the ''Financial Times'' called its "idiosyncratic philosophy of 'Shirota-ism,'" namely that it should sell its products at an affordable price, and that a healthy intestine promotes longer life. History Since 1963, Yakult has employed women known as "Yakult ladies" (ヤクルトレディー; ''Yakuruto redī'') or "Yakult aunties" (ヤクルトおばさん; ''Yakuruto obasan'') to sell or deliver the products to individuals at their homes while traveling on bicycles or motorcycles. The initiative, meant to utilize Japanese women in the workforce, is responsible for up to 60% of all bottled Ya ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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1899 Births
Events January * January 1 ** Spanish rule formally ends in Cuba with the cession of Spanish sovereignty to the U.S., concluding 400 years of the Spanish Empire in the Americas.''The American Monthly Review of Reviews'' (February 1899), pp. 153-157 ** In Samoa, followers of Mataafa, claimant to the rule of the island's subjects, burn the town of Upolu in an ambush of followers of other claimants, Malietoa Tanus and Tamasese, who are evacuated by the British warship HMS ''Porpoise''. ** Queens and Staten Island become administratively part of New York City. * January 2 – Theodore Roosevelt is inaugurated as Governor of New York at the age of 39. * January 3 – A treaty of alliance is signed between Russia and Afghanistan. * January 5 – **A fierce battle is fought between American troops and Filipino defenders at the town of Pililla on the island of Luzon. *The collision of a British steamer and a French steamer kills 12 people on the English Channel. * Jan ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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1982 Deaths
Events January * January 1 – In Malaysia and Singapore, clocks are adjusted to the same time zone, UTC+8 (GMT+8.00). * January 13 – Air Florida Flight 90 crashes shortly after takeoff into the 14th Street bridges, 14th Street Bridge in Washington, D.C., United States, then falls into the Potomac River, killing 78 people. * January 14–17, 2022 North American winter storm, January 14 – An Ethiopian Air Force Antonov An-26 with an unknown registration crashed near Addis Ababa, Ethiopia, killing all 73 occupants on board. * January 18 – 1982 Thunderbirds Indian Springs Diamond Crash: Four Northrop T-38 aircraft of the United States Air Force crash at Indian Springs Air Force Auxiliary Field, Nevada, killing all 4 pilots. * January 26 – Mauno Koivisto is elected President of Finland. * January 27 – The government of Garret FitzGerald in Republic of Ireland, Ireland is defeated 82–81 on its budget; the 22nd Dáil is dissolved. * January 30 – The first computer ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Japanese Military Doctors
Japanese may refer to: * Something from or related to Japan, an island country in East Asia * Japanese language, spoken mainly in Japan * Japanese people, the ethnic group that identifies with Japan through ancestry or culture ** Japanese diaspora, Japanese emigrants and their descendants around the world * Japanese citizens, nationals of Japan under Japanese nationality law ** Foreign-born Japanese, naturalized citizens of Japan * Japanese writing system, consisting of kanji and kana * Japanese cuisine, the food and food culture of Japan See also * List of Japanese people * * Japonica (other) * Japanese studies , sometimes known as Japanology in Europe, is a sub-field of area studies or East Asian studies involved in social sciences and humanities research on Japan. It incorporates fields such as the study of Japanese language, history, culture, litera ... {{disambiguation Language and nationality disambiguation pages ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |