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Masashi Yanagisawa
is a Japanese-American molecular biologist and physician, famous for his discovery of the hormone endothelin and the neuropeptide orexin, the absence of which is the cause of narcolepsy. He is currently the Director of the International Institute for Integrative Sleep Medicine, University of Tsukuba, and an adjunct professor at the Department of Molecular Genetics, University of Texas Southwestern Medical Center. Early life and education Yanagisawa was born in Tokyo in 1960. His father was a surgeon and, thanks to his background in electrical and electronic engineering, an electrophysiology researcher. He graduated from Musashi Junior and Senior High School in 1979, and entered the University of Tsukuba to study medicine. After obtaining an MD in 1985, he pursued a PhD at the same institute, completing it 3 years later. Career Immediately after obtaining his PhD, Yanagisawa started his career as a postdoctoral fellow at the Department of Pharmacology of the University of ...
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Keio Medical Science Prize
The Keio Medical Science Prize ( Japanese: 慶應医学賞) is a Japanese prize in medical sciences. Introduction The prize is awarded to scientists who made significant contributions to the field of medical sciences or life sciences. And these contributions can further promote the peace and prosperity of mankind and human society.The Keio Medical Science Prize
The prize award is 20 million Japanese Yen (approximately 180,000 US$). A is also awarded to the winner. Every year maximum two winners are awarded. A prize ceremo ...
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Narcolepsy
Narcolepsy is a long-term neurological disorder that involves a decreased ability to regulate sleep–wake cycles. Symptoms often include periods of excessive daytime sleepiness and brief involuntary sleep episodes. About 70% of those affected also experience episodes of sudden loss of muscle strength, known as cataplexy. Narcolepsy paired with cataplexy is evidenced to be an autoimmune disorder. These experiences of cataplexy can be brought on by strong emotions. Less commonly, there may be vivid hallucinations or an inability to move (sleep paralysis) while falling asleep or waking up. People with narcolepsy tend to sleep about the same number of hours per day as people without, but the quality of sleep tends to be lessened. Narcolepsy is a clinical syndrome of hypothalamic disorder, however, the exact cause of narcolepsy is unknown, with potentially several causes. In up to 10% of cases, there is a family history of the disorder. Often, those affected have low levels o ...
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Michael Stuart Brown
Michael Stuart Brown ForMemRS NAS AAA&S APS (born April 13, 1941) is an American geneticist and Nobel laureate. He was awarded the Nobel Prize in Physiology or Medicine with Joseph L. Goldstein in 1985 for describing the regulation of cholesterol metabolism. Education and early life Brown was born in Brooklyn, New York, the son of Evelyn, a homemaker, and Harvey Brown, a textile salesman. He graduated from Cheltenham High School (Wyncote, Pennsylvania). Brown graduated from the University of Pennsylvania in 1962 and received his M.D. from the University of Pennsylvania School of Medicine in 1966. Career and research Moving to the University of Texas Michael liked vann Warner Health Science Center in Dallas, now the UT Southwestern Medical Center, Brown and colleague Joseph L. Goldstein researched cholesterol metabolism and discovered that human cells have low-density lipoprotein (LDL) receptors that extract cholesterol from the bloodstream. The lack of sufficient LDL rec ...
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Joseph L
Joseph is a common male given name, derived from the Hebrew Yosef (יוֹסֵף). "Joseph" is used, along with "Josef", mostly in English, French and partially German languages. This spelling is also found as a variant in the languages of the modern-day Nordic countries. In Portuguese and Spanish, the name is "José". In Arabic, including in the Quran, the name is spelled '' Yūsuf''. In Persian, the name is "Yousef". The name has enjoyed significant popularity in its many forms in numerous countries, and ''Joseph'' was one of the two names, along with ''Robert'', to have remained in the top 10 boys' names list in the US from 1925 to 1972. It is especially common in contemporary Israel, as either "Yossi" or "Yossef", and in Italy, where the name "Giuseppe" was the most common male name in the 20th century. In the first century CE, Joseph was the second most popular male name for Palestine Jews. In the Book of Genesis Joseph is Jacob's eleventh son and Rachel's first son, ...
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Kyoto
Kyoto (; Japanese: , ''Kyōto'' ), officially , is the capital city of Kyoto Prefecture in Japan. Located in the Kansai region on the island of Honshu, Kyoto forms a part of the Keihanshin metropolitan area along with Osaka and Kobe. , the city had a population of 1.46 million. The city is the cultural anchor of a substantially larger metropolitan area known as Greater Kyoto, a metropolitan statistical area (MSA) home to a census-estimated 3.8 million people. Kyoto is one of the oldest municipalities in Japan, having been chosen in 794 as the new seat of Japan's imperial court by Emperor Kanmu. The original city, named Heian-kyō, was arranged in accordance with traditional Chinese feng shui following the model of the ancient Chinese capital of Chang'an/ Luoyang. The emperors of Japan ruled from Kyoto in the following eleven centuries until 1869. It was the scene of several key events of the Muromachi period, Sengoku period, and the Boshin War, such as the Ōnin War, ...
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Japan Science And Technology Agency
The Japan Science and Technology Agency (JST; Japanese: 科学技術振興機構) is a Japanese government agency which aims to build infrastructure that supports knowledge creation and dissemination in Japan. It is one of the , overseen by the Ministry of Education, Culture, Sports, Science and Technology (MEXT) and the Council for Science, Technology and Innovation (CSTI). It operates from headquarters in Kawaguchi, Saitama in the Greater Tokyo Area, and in Chiyoda in central Tokyo. The agency formed in 2003, as successor to the Japan Science and Technology Corporation. The corporation had formed in 1996 through the merging of the Japan Information Center of Science and Technology (JICST, est. 1957) and the Research Development Corporation of Japan (JRDC, est. 1961). Among other activities, the agency runs J-STAGE, an "electronic journal platform for science and technology information in Japan," and publishes the ''Journal of Information Processing and Management'' (). As a ...
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Graduate School Of Medicine And Faculty Of Medicine, Kyoto University
Graduate School of Medicine and Faculty of Medicine (京都大学大学院医学研究科・医学部) is one of the schools at the Kyoto University. The Faculty and the Graduate School operate as one. According to the QS World University Rankings for Medicine 2020, Kyoto University is ranked second in Japan after University of Tokyo. Professor Shinya Yamanaka received the Nobel Prize in Physiology or Medicine in 2012 for his work on iPS cells. Also, Prof. Emer. Tasuku Honjo, who is also a graduate of Kyoto University, won the Nobel Prize in Physiology or Medicine in 2018 for his discovery and theory of immune checkpoint inhibitors. History In 1899, College of Medicine (医科大学) and its hospital (now ) was established Imperial University of Kyoto. In 1919, The college is renamed Faculty of Medicine (医学部). Established in 1939, the School of Medicine's Department of Pharmacy became an independent Faculty of Pharmaceutical Sciences and Graduate School of Pharmaceu ...
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Pharmacology
Pharmacology is a branch of medicine, biology and pharmaceutical sciences concerned with drug or medication action, where a drug may be defined as any artificial, natural, or endogenous (from within the body) molecule which exerts a biochemical or physiological effect on the cell, tissue, organ, or organism (sometimes the word ''pharmacon'' is used as a term to encompass these endogenous and exogenous bioactive species). More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function. If substances have medicinal properties, they are considered pharmaceuticals. The field encompasses drug composition and properties,functions,sources,synthesis and drug design, molecular and cellular mechanisms, organ/systems mechanisms, signal transduction/cellular communication, molecular diagnostics, interactions, chemical biology, therapy, and medical applications and antipathogenic capabili ...
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Postdoctoral Researcher
A postdoctoral fellow, postdoctoral researcher, or simply postdoc, is a person professionally conducting research after the completion of their doctoral studies (typically a PhD). The ultimate goal of a postdoctoral research position is to pursue additional research, training, or teaching in order to have better skills to pursue a career in academia, research, or any other field. Postdocs often, but not always, have a temporary academic appointment, sometimes in preparation for an academic faculty position. They continue their studies or carry out research and further increase expertise in a specialist subject, including integrating a team and acquiring novel skills and research methods. Postdoctoral research is often considered essential while advancing the scholarly mission of the host institution; it is expected to produce relevant publications in peer-reviewed academic journals or conferences. In some countries, postdoctoral research may lead to further formal qualification ...
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Musashi Junior And Senior High School
is a privately owned school for boys based in Nerima, Tokyo, Japan. History The school was founded in 1922 by industrialist Nezu Kaichirō, as Musashi High School. The school was one of the first institutions of its type to use a seven-year system of education, taking students up to the equivalent of the first two years of university under the current system of education. Musashi became a prototype for the modern integrated junior and senior high schools that now prevails throughout Japan. After the education reforms of 1948, the school was divided into Musashi Senior High School and Musashi Junior High School. Musashi University was founded in 1949 and forms part of the same legal entity. Admissions The school operates a highly selective admissions program attracting students from across the city. Graduates have been successful in gaining admission to many of Japan's most selective universities. The school is unusual in the fact that it has few written rules and has no un ...
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Electrophysiology
Electrophysiology (from Greek , ''ēlektron'', "amber" Electron#Etymology">etymology of "electron" , ''physis'', "nature, origin"; and , ''-logia'') is the branch of physiology that studies the electrical properties of biological cells and tissues. It involves measurements of voltage changes or electric current or manipulations on a wide variety of scales from single ion channel proteins to whole organs like the heart. In neuroscience, it includes measurements of the electrical activity of neurons, and, in particular, action potential activity. Recordings of large-scale electric signals from the nervous system, such as electroencephalography, may also be referred to as electrophysiological recordings. They are useful for electrodiagnosis and monitoring. Definition and scope Classical electrophysiological techniques Principle and mechanisms Electrophysiology is the branch of physiology that pertains broadly to the flow of ions ( ion current) in biological tissues and, in pa ...
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Electronic Engineering
Electronics engineering is a sub-discipline of electrical engineering which emerged in the early 20th century and is distinguished by the additional use of active components such as semiconductor devices to amplify and control electric current flow. Previously electrical engineering only used passive devices such as mechanical switches, resistors, inductors and capacitors. It covers fields such as: analog electronics, digital electronics, consumer electronics, embedded systems and power electronics. It is also involved in many related fields, for example solid-state physics, radio engineering, telecommunications, control systems, signal processing, systems engineering, computer engineering, instrumentation engineering, electric power control, robotics. The Institute of Electrical and Electronics Engineers (IEEE) is one of the most important professional bodies for electronics engineers in the US; the equivalent body in the UK is the Institution of Engineering and Te ...
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