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Margaritaria Discoidea
''Margaritaria discoidea'' is a tree in the family Phyllanthaceae, commonly known as the pheasant-berry, egossa red pear or bushveld peacock-berry. These trees are native to the warmer, higher rainfall areas of Africa. Taxonomy This species has a complex taxonomic history with many synonyms (see taxobox); partially because of its morphological variability. These trees were formerly placed in the genus ''Phyllanthus'' and in the family Euphorbiaceae. 4 varieties are now recognized (1981), these having in the past been treated variously as distinct species, subspecies or synonymous with typical ''M. discoidea''. In KwaZulu-Natal, South Africa, there are 3 varieties: * ''M. discoidea'' var. ''discoidea'' * ''M. discoidea'' var. ''fagifolia'' * ''M. discoidea'' var. ''nitida'' Distribution This species is distributed from the coastal areas of the Eastern Cape, South Africa, to tropical Africa, as far as Senegal in West Africa. Description A medium to tall tree in forest and riverin ...
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Henri Ernest Baillon
Henri Ernest Baillon was a French botanist and physician. He was born in Calais on 30 November 1827 and died in Paris on 19 July 1895. Baillon spent his professional life as a professor of natural history, and he published numerous works on botany. He was appointed to the Légion d'honneur in 1867 and joined the Royal Society The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, r ... in 1894. Baillon put together the "Dictionnaire de botanique", for which Auguste Faguet produced the wood engravings. The plant genus '' Baillonia'' (family Verbenaceae) was named in his honor by Henri Théophile Bocquillon.
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Securinine
Securinine is an alkaloid found in ''Securinega suffruticosa'' and ''Phyllanthus niruri''. Pharmacology Securinine has pro-convulsant effects and it has a strong spastic effect, similar to the actions of strychnine. Securinine is a GABA-A antagonist. See also * Norsecurinine * Phenazine Phenazine is an organic compound with the formula (C6H4)2N2. It is a dibenzo annulation, annulated pyrazine, and the parent substance of many dyestuffs, such as the toluylene red, indulines, and safranines (and the closely related eurhodines). Phe ... References {{Reflist Tetracyclic compounds Nitrogen heterocycles Lactones Alkaloids Furanones Cyclohexenes Withdrawn drugs ...
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Ubangi Province
Ubangi Province (1962−1966) was a former province in the north of Zaire, formed from a division of the first Équateur Province. It was then reincorporated into Équateur Province in 1966. After the 2015 reorganisation of its provinces, what used to Ubangi province, now lies within Nord-Ubangi and Sud-Ubangi provinces of the Democratic Republic of the Congo The Democratic Republic of the Congo (french: République démocratique du Congo (RDC), colloquially "La RDC" ), informally Congo-Kinshasa, DR Congo, the DRC, the DROC, or the Congo, and formerly and also colloquially Zaire, is a country in .... See also * References Province of Équateur Former provinces of the Democratic Republic of the Congo (pre-1966) 1962 establishments in the Republic of the Congo (Léopoldville) 1966 disestablishments in the Democratic Republic of the Congo {{DRCongo-geo-stub ...
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Blennorrhoea
Blennorrhoea aka blennorrhagia or myxorrhoea ('blenno' mucus, 'rrhoea' flow), is a medical term denoting an excessive discharge of watery mucus, especially from the urethra or the vagina, and also used in ophthalmology for an abnormal discharge from the eye, but now regarded as a synonym for conjunctivitis and accordingly rarely used. Inclusion blennorrhoea aka chlamydial conjunctivitis or swimming pool conjunctivitis, is a condition affecting infants born to women infected with inclusion conjunctivitis of the urogenital tract, frequently caused by ''Chlamydia trachomatis'', a sexually transmitted organism and often going unnoticed as a mild infection. Such infants may develop acute neonatal conjunctivitis within a few days of birth, and smears from their eyes reveal the presence of characteristic inclusion bodies Inclusion bodies are aggregates of specific types of protein found in neurons, a number of tissue cells including red blood cells, bacteria, viruses, and plants. Inclus ...
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Ivory Coast
Ivory Coast, also known as Côte d'Ivoire, officially the Republic of Côte d'Ivoire, is a country on the southern coast of West Africa. Its capital is Yamoussoukro, in the centre of the country, while its largest city and economic centre is the port city of Abidjan. It borders Guinea to Guinea–Ivory Coast border, the northwest, Liberia to Ivory Coast–Liberia border, the west, Mali to Ivory Coast–Mali border, the northwest, Burkina Faso to Burkina Faso–Ivory Coast border, the northeast, Ghana to Ghana–Ivory Coast border, the east, and the Gulf of Guinea (Atlantic Ocean) to the south. Its official language is French language, French, and indigenous languages are also widely used, including Bété languages, Bété, Baoulé language, Baoulé, Dyula language, Dioula, Dan language, Dan, Anyin language, Anyin, and Senari languages, Cebaara Senufo. In total, there are around 78 different Languages of Ivory Coast, languages spoken in Ivory Coast. The country has a Religion ...
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Margaritaria Discoidea Medicine Bark
''Margaritaria'' is a plant genus of the family Phyllanthaceae first published as a genus in 1782. It is the smallest pantropical A pantropical ("all tropics") distribution is one which covers Tropics, tropical regions of both hemispheres. Examples of species include caecilians, modern sirenians and the plant genera ''Acacia'' and ''Bacopa''. ''Neotropical'' is a zoogeogra ... genus of the Phyllanthaceae and, formerly, of the Euphorbiaceae, widely distributed in tropical and subtropical regions of Asia, Africa, Australia, North and South America, and various oceanic islands.Govaerts, R., Frodin, D.G. & Radcliffe-Smith, A. (2000). World Checklist and Bibliography of Euphorbiaceae (and Pandaceae) 1-4: 1-1622. The Board of Trustees of the Royal Botanic Gardens, Kew. ;Species References Phyllanthaceae Phyllanthaceae genera Pantropical flora Taxa named by Carl Linnaeus the Younger {{Phyllanthaceae-stub ...
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Indomethacin
Indometacin, also known as indomethacin, is a nonsteroidal anti-inflammatory drug (NSAID) commonly used as a prescription medication to reduce fever, pain, stiffness, and swelling from inflammation. It works by inhibiting the production of prostaglandins, endogenous signaling molecules known to cause these symptoms. It does this by inhibiting cyclooxygenase, an enzyme that catalyzes the production of prostaglandins. It was patented in 1961 and approved for medical use in 1963. It is on the World Health Organization's List of Essential Medicines. In 2020, it was the 320th most commonly prescribed medication in the United States, with more than 800thousand prescriptions. Medical uses As an NSAID, indometacin is an analgesic, anti-inflammatory, and antipyretic. Clinical indications for indometacin include: Joint diseases *rheumatoid arthritis *ankylosing spondylitis *osteoarthritis *gouty arthritis *acute painful shoulder bursitis or tendinitis Headaches *Trigeminal autonomic ceph ...
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Histamine
Histamine is an organic nitrogenous compound involved in local immune responses, as well as regulating physiological functions in the gut and acting as a neurotransmitter for the brain, spinal cord, and uterus. Since histamine was discovered in 1910, it has been considered a local hormone ( autocoid) because it lacks the classic endocrine glands to secrete it; however, in recent years, histamine has been recognized as a central neurotransmitter. Histamine is involved in the inflammatory response and has a central role as a mediator of itching. As part of an immune response to foreign pathogens, histamine is produced by basophils and by mast cells found in nearby connective tissues. Histamine increases the permeability of the capillaries to white blood cells and some proteins, to allow them to engage pathogens in the infected tissues. It consists of an imidazole ring attached to an ethylamine chain; under physiological conditions, the amino group of the side-chain is ...
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Carrageenan
Carrageenans or carrageenins ( ; ) are a family of natural linear sulfated polysaccharides that are extracted from red edible seaweeds. Carrageenans are widely used in the food industry, for their gelling, thickening, and stabilizing properties. Their main application is in dairy and meat products, due to their strong binding to food proteins. In recent years, carrageenans have emerged as a promising candidate in tissue engineering and regenerative medicine applications as they resemble native glycosaminoglycans (GAGs). They have been mainly used for tissue engineering, wound coverage and drug delivery. Carrageenans contain 15-40% ester-sulfate content, which makes them anionic polysaccharides. They can be mainly categorized into three different classes based on their sulfate content. Kappa-carrageenan has one sulfate group per disaccharide, iota-carrageenan has two, and lambda-carrageenan has three. The most well-known and most important red seaweed used for manufacturing the h ...
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Oedema
Edema, also spelled oedema, and also known as fluid retention, dropsy, hydropsy and swelling, is the build-up of fluid in the body's tissue. Most commonly, the legs or arms are affected. Symptoms may include skin which feels tight, the area may feel heavy, and joint stiffness. Other symptoms depend on the underlying cause. Causes may include venous insufficiency, heart failure, kidney problems, low protein levels, liver problems, deep vein thrombosis, infections, angioedema, certain medications, and lymphedema. It may also occur after prolonged sitting or standing and during menstruation or pregnancy. The condition is more concerning if it starts suddenly, or pain or shortness of breath is present. Treatment depends on the underlying cause. If the underlying mechanism involves sodium retention, decreased salt intake and a diuretic may be used. Elevating the legs and support stockings may be useful for edema of the legs. Older people are more commonly affected. The ...
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Analgesic
An analgesic drug, also called simply an analgesic (American English), analgaesic (British English), pain reliever, or painkiller, is any member of the group of drugs used to achieve relief from pain (that is, analgesia or pain management). It is typically used to induce cooperation with a medical procedure. Analgesics are conceptually distinct from anesthetics, which temporarily reduce, and in some instances eliminate, sensation, although analgesia and anesthesia are neurophysiologically overlapping and thus various drugs have both analgesic and anesthetic effects. Analgesic choice is also determined by the type of pain: For neuropathic pain, traditional analgesics are less effective, and there is often benefit from classes of drugs that are not normally considered analgesics, such as tricyclic antidepressants and anticonvulsants. Various analgesics, such as many NSAIDs, are available over the counter in most countries, whereas various others are prescription drugs owi ...
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Anti-inflammatory
Anti-inflammatory is the property of a substance or treatment that reduces inflammation or swelling. Anti-inflammatory drugs, also called anti-inflammatories, make up about half of analgesics. These drugs remedy pain by reducing inflammation as opposed to opioids, which affect the central nervous system to block pain signaling to the brain. Nonsteroidal anti-inflammatory drugs Nonsteroidal anti-inflammatory drugs (NSAIDs) alleviate pain by counteracting the cyclooxygenase (COX) enzyme. On its own, COX enzyme synthesizes prostaglandins, creating inflammation. In whole, the NSAIDs prevent the prostaglandins from ever being synthesized, reducing or eliminating the inflammation and resulting pain. Some common examples of NSAIDs are aspirin, ibuprofen, and naproxen. The newer specific COX-inhibitors are not classified together with the traditional NSAIDs, even though they presumably share the same mode of action. On the other hand, there are analgesics that are commonly associa ...
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