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Magdi Yacoub
Sir Magdi Habib Yacoub ( ; born 16 November 1935) is an Egyptian-British retired professor of cardiothoracic surgery at Imperial College London, best known for his early work in repairing heart valves with surgeon Donald Ross, adapting the Ross procedure, where the diseased aortic valve is replaced with the person's own pulmonary valve, devising the arterial switch operation (ASO) in transposition of the great arteries, and establishing the heart transplantation centre at Harefield Hospital in 1980 with a heart transplant for Derrick Morris, who at the time of his death was Europe's longest-surviving heart transplant recipient. Yacoub subsequently performed the UK's first combined heart and lung transplant in 1983. From 1986 to 2006, he held the position of British Heart Foundation Professor of Cardiothoracic Surgery at the National Heart and Lung Institute, Imperial College Faculty of Medicine. He is the founding editor of the journal ''Disease Models & Mechanisms''. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bilbeis
Bilbeis ( ; Bohairic ' is an ancient fortress city on the eastern edge of the southern Nile Delta in Egypt, the site of the ancient city and former bishopric of Phelbes and a Latin Catholic titular see. The city is small in size but densely populated, with over 407,300 residents. It also houses the Egyptian Air Force Academy complex, which contains the town's largest public school in Al-Zafer. Coptic tradition says that Bilbeis was one of the stopping places of the Holy Family during the Flight into Egypt. History The city was important enough in the Roman province of Augustamnica Secunda to become a bishopric. Situated on a caravan and natural invasion route from the east, Bilbeis was conquered in 640 by the Arabs. Amr ibn al-As besieged and took the city defended by a Byzantine general called al-Ardubun. According to a Muslim legend, Armanusa, the daughter of Muqawqis lived in Bilbeis. In 727 some of the Qays tribe were resettled here and later chain of fort ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Egyptians In The United Kingdom
Egyptians in the United Kingdom or Egyptian Britons are Egyptian citizens or people of Egyptian ancestry who are citizens or residents of the United Kingdom. Migration history In Irish mythology, Scottish mythology, and pseudo-history, an Egyptian princess named Scota is mentioned as having arrived in today's Scotland (and/or in Ireland) in a very early period of these countries' history. The historical veracity of the story is greatly doubted, however. And under the Roman Empire, Britannia and Egypt were two provinces of a single empire which had considerable trade and interaction between its constituent parts. However, if any Egyptians settled in Roman Britain, there was little evidence left of their presence. Egyptians historically have been averse to emigrating from their country, even when suffering with significant poverty. As such, prior to the late 1960s, only small numbers of Egyptians moved to the United Kingdom, and even then mostly for the purposes of study. As the Eg ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bradshaw Lecture
The Bradshaw Lectures are lectureships given at the invitation of the Royal College of Physicians and the Royal College of Surgeons of England The Royal College of Surgeons of England (RCS England) is an independent professional body and registered charity that promotes and advances standards of surgery, surgical care for patients, and regulates surgery and dentistry in England and Wa .... It is held on alternate years in rotation with the Hunterian Oration. List of past lecturers at Royal College of Physicians List of past lecturers at Royal College of Surgeons of England The lecture is biennial (annual until 1993) on a topic in the field of surgery, customarily given by a senior member of the Council on or about the day preceding the second Thursday of December. (Given in alternate years, with the Hunterian Oration given in the intervening years). See also * Fitzpatrick Lecture * Goulstonian Lecture * Harveian Oration * Lumleian Lectures * Milroy Lectures Ref ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Disease Models & Mechanisms
''Disease Models & Mechanisms'' (DMM) is a monthly peer-reviewed Open Access biomedical journal published by The Company of Biologists that launched in 2008. DMM is partnered with Publons, is part of the Review Commons initiative and has two-way integration with bioRxiv. Scope and content DMM publishes original research, resources and reviews that focus on the use of model systems to better understand, diagnose and treat human disease. Model systems of interest include: * Vertebrates such as mice, zebrafish, frogs, rats and other mammals * Invertebrates such as ''Drosophila melanogaster'' and ''Caenorhabditis elegans'' * Unique ''in vitro'' or '' ex vivo'' models, such as stem-cell-based models, organoids and systems based on patient material * Microorganisms such as yeast and ''Dictyostelium'' * Other biological systems with relevance to human disease research Disease areas of interest include: * Cancer * Neurodegenerative and neurological diseases * Psychiatric ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Imperial College School Of Medicine
Imperial College School of Medicine (ICSM) is the undergraduate medical school of Imperial College London in England and one of the United Hospitals. It is part of the college's Imperial College Faculty of Medicine, Faculty of Medicine and was formed by the merger of several historic medical schools. Its core campuses are located at South Kensington, St Mary's Hospital, London, St Mary's, Charing Cross Hospital, Charing Cross, Hammersmith Hospital, Hammersmith and Chelsea and Westminster Hospital, Chelsea and Westminster. History The medical school at Imperial College dates back to the founding of Charing Cross Hospital Medical School in 1823, which was followed by other medical schools including Chelsea and Westminster Hospital Medical School, St Mary's Hospital Medical School, and the Royal Postgraduate Medical School. Imperial College London first gained a medical school by merger with St Mary's Hospital Medical School, St Mary's Medical School in 1988. The current School o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
British Heart Foundation
The British Heart Foundation (BHF) is a cardiovascular research charity in the United Kingdom. It funds medical research related to heart and circulatory diseases and their risk factors, and runs influencing work aimed at shaping public policy and raising awareness. In 2021, a study conducted by YouGov ranked the British Heart Foundation as the top charity or organisation in the UK by per cent of adults who hold a positive opinion of the organisation. Foundation The British Heart Foundation was founded in 1961 by a group of medical professionals who were concerned about the increasing death rate from cardiovascular disease. They wanted to fund extra research into the causes, diagnosis, treatment, and prevention of heart and circulatory diseases. Leadership Dr Charmaine Griffiths has been the BHF's Chief Executive since February 2020, succeeding Simon Gillespie OBE. Professor Bryan Williams OBE became the charity's first Chief Scientific and Medical Officer (CSMO) in Decembe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heart–lung Transplant
A heart–lung transplant is a procedure carried out to replace both failing heart and lungs in a single operation. Due to a shortage of suitable donors and because both heart and lung have to be transplanted together, it is a rare procedure; only about a hundred such transplants are performed each year in the United States. Procedure The patient is anesthetised. When the donor organs arrive, they are checked for fitness; if any organs show signs of damage, they are discarded and the operation cancelled. Once suitable donor organs are present, the surgeon makes an incision starting above and finishing below the sternum, cutting all the way to the bone. The skin edges are retracted to expose the sternum. Using a bone saw, the sternum is cut down the middle. Rib spreaders are inserted in the cut, and spread the ribs to give access to the heart and lungs of the patient. The patient is connected to a heart–lung machine, which circulates and oxygenates blood. The surgeon removes ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Derrick Morris
Derrick Morris (24 March 1930 – 30 July 2005) was, at the time of his death, Europe's longest-surviving heart transplant recipient, living 25 years after the transplant performed by Sir Magdi Yacoub in 1980. He died from an illness that was not heart or transplant related. Morris had his first heart attack in 1975 and was told to expect to live only months. He became an active campaigner against heart disease, an advocate of organ donation as well as a symbol of the success of organ transplantation. Early life and illness Derrick Morris was born on 24 March 1930. He was from Swansea in Wales, and was working as a supervisor at Swansea Docks when he suffered his first heart attack in 1975. He was given only a 15% chance of survival, and was told to "live six months at a time". [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heart Transplant
A heart transplant, or a cardiac transplant, is a surgical transplant procedure performed on patients with end-stage heart failure when other medical or surgical treatments have failed. , the most common procedure is to take a functioning heart from a recently deceased organ donor (brain death is the most common) and implant it into the patient. The patient's own heart is either removed and replaced with the donor heart ( orthotopic procedure) or, much less commonly, the recipient's diseased heart is left in place to support the donor heart (heterotopic, or "piggyback", transplant procedure). Approximately 5,000 heart transplants are performed each year worldwide, more than half of which are in the US. Post-operative survival periods average 15 years. Heart transplantation is not considered to be a cure for heart disease; rather it is a life-saving treatment intended to improve the quality and duration of life for a recipient. History American medical researcher Simon Fle ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Arterial Switch Operation
Arterial switch operation (ASO) or arterial switch, is an open heart surgical procedure used to correct dextro-transposition of the great arteries (d-TGA). Its development was pioneered by Canadian cardiac surgeon William Mustard and it was named for Brazilian cardiac surgeon Adib Jatene, who was the first to use it successfully. It was the first method of d-TGA repair to be attempted, but the last to be put into regular use because of technological limitations at the time of its conception. Use of the arterial switch is historically preceded by two atrial switch methods: the Senning and Mustard procedures. The atrial switch, which was an attempt to correct the physiology of transposition, had significant shortcomings that the arterial switch improved upon, in particular a reduced kinking of the coronary arteries when combined with the LeCompte maneuver. The end result is that the aorta is repositioned behind the pulmonary arteries, functionally lengthening it and causin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pulmonary Valve
The pulmonary valve (sometimes referred to as the pulmonic valve) is a valve of the heart that lies between the right ventricle and the pulmonary artery, and has three cusps. It is one of the four valves of the heart and one of the two semilunar valves, the other being the aortic valve. Similar to the aortic valve, the pulmonary valve opens in ventricular systole when the pressure in the right ventricle rises above the pressure in the pulmonary artery. At the end of ventricular systole, when the pressure in the right ventricle falls rapidly, the pressure in the pulmonary artery closes the pulmonary valve. The closure of the pulmonary valve contributes to the P2 component of the second heart sound (S2). Structure The pulmonary orifice lies nearly in the horizontal plane, and is situated at a superior level than the aortic orifice. Cusps File:Lunules of semilunar leaflets of pulmonary valve.png File:Anterior semilunar leaflet of pulmonary valve.png File:Right semilunar le ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aortic Valve
The aortic valve is a valve in the heart of humans and most other animals, located between the left ventricle and the aorta. It is one of the four valves of the heart and one of the two semilunar valves, the other being the pulmonary valve. The aortic valve normally has three cusps or leaflets, although in 1–2% of the population it is found to congenitally have two leaflets. The aortic valve is the last structure in the heart the blood travels through before stopping the flow through the systemic circulation. Structure The aortic valve normally has three cusps however there is some discrepancy in their naming. They may be called the left coronary, right coronary and non-coronary cusp. Some sources also advocate they be named as a left, right and posterior cusp. Anatomists have traditionally named them the left posterior (origin of left coronary), anterior (origin of the right coronary) and right posterior. The three cusps, when the valve is closed, contain a sinus called ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
