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MAGOH
Protein mago nashi homolog is a protein that in humans is encoded by the ''MAGOH'' gene. Drosophila that have mutations in their mago nashi (grandchildless) gene produce progeny with defects in germplasm assembly and germline development. This gene encodes the mammalian mago nashi homolog. In mammals, mRNA expression is not limited to the germ plasm, but is expressed ubiquitously in adult tissues and can be induced by serum stimulation of quiescent fibroblasts. Interactions MAGOH has been shown to interact with RBM8A and NXF1 Nuclear RNA export factor 1, also known as NXF1 or TAP, is a protein which in humans is encoded by the ''NXF1'' gene. Function This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a no .... In Drosophila melanogaster, Mago Nashi and Tsunagi/Y14 (core components of the exon junction complex) form a complex with a novel zinc finger protein, Ranshi, that has a role in oocyte differentiation. Refer ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
RBM8A RNA-binding protein 8A is a protein that in humans is encoded by the ''RBM8A'' gene. This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. Two alternative start codons result in two forms of the protein, and this gene also uses multiple polyadenylation sites. Interactions RBM8A has been shown to interact with IPO13, MAGOH and UPF3A. Related gene problems *TAR syndrome *1q21.1 deletion syndrome *1q21.1 duplication syndrome 1q21.1 duplication ... [...More Info...] [...Related Items...] OR: [Wikipedia] |