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Legionella Gormanii
''Legionella gormanii'' is a Gram-negative bacterium from the genus ''Legionella'' which was isolated from soil samples from a creek bank in Atlanta and from the bronchial brush specimen of a patient who suffered from pneumonia. ''L. gormanii'' can cause atypical pneumonia Atypical pneumonia, also known as walking pneumonia, is any type of pneumonia not caused by one of the pathogens most commonly associated with the disease. Its clinical presentation contrasts to that of "typical" pneumonia. A variety of microorgan ... together with '' L. pneumophila''. References Legionellales Bacteria described in 1980 {{Legionellales-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gram-negative
Gram-negative bacteria are bacteria that do not retain the crystal violet stain used in the Gram staining method of bacterial differentiation. They are characterized by their cell envelopes, which are composed of a thin peptidoglycan cell wall sandwiched between an inner cytoplasmic cell membrane and a bacterial outer membrane. Gram-negative bacteria are found in virtually all environments on Earth that support life. The gram-negative bacteria include the model organism ''Escherichia coli'', as well as many pathogenic bacteria, such as '' Pseudomonas aeruginosa'', '' Chlamydia trachomatis'', and '' Yersinia pestis''. They are a significant medical challenge as their outer membrane protects them from many antibiotics (including penicillin), detergents that would normally damage the inner cell membrane, and lysozyme, an antimicrobial enzyme produced by animals that forms part of the innate immune system. Additionally, the outer leaflet of this membrane comprises a complex ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bacterium
Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among the first life forms to appear on Earth, and are present in most of its habitats. Bacteria inhabit soil, water, acidic hot springs, radioactive waste, and the deep biosphere of Earth's crust. Bacteria are vital in many stages of the nutrient cycle by recycling nutrients such as the fixation of nitrogen from the atmosphere. The nutrient cycle includes the decomposition of dead bodies; bacteria are responsible for the putrefaction stage in this process. In the biological communities surrounding hydrothermal vents and cold seeps, extremophile bacteria provide the nutrients needed to sustain life by converting dissolved compounds, such as hydrogen sulphide and methane, to energy. Bacteria also live in symbiotic and parasitic r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Legionella
''Legionella'' is a genus of pathogenic gram-negative bacteria that includes the species '' L. pneumophila'', causing legionellosis (all illnesses caused by ''Legionella'') including a pneumonia-type illness called Legionnaires' disease and a mild flu-like illness called Pontiac fever. ''Legionella'' may be visualized with a silver stain or cultured in cysteine-containing media such as buffered charcoal yeast extract agar. It is common in many environments, including soil and aquatic systems, with at least 50 species and 70 serogroups identified. These bacteria, however, are not transmissible from person to person; furthermore, most people exposed to the bacteria do not become ill. Most outbreaks are traced to poorly maintained cooling towers. The side chains of the cell wall carry the bases responsible for the somatic antigen specificity of these organisms. The chemical composition of these side chains both with respect to components and arrangement of the different sugars de ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Atlanta
Atlanta ( ) is the capital and most populous city of the U.S. state of Georgia. It is the seat of Fulton County, the most populous county in Georgia, but its territory falls in both Fulton and DeKalb counties. With a population of 498,715 living within the city limits, it is the eighth most populous city in the Southeast and 38th most populous city in the United States according to the 2020 U.S. census. It is the core of the much larger Atlanta metropolitan area, which is home to more than 6.1 million people, making it the eighth-largest metropolitan area in the United States. Situated among the foothills of the Appalachian Mountains at an elevation of just over above sea level, it features unique topography that includes rolling hills, lush greenery, and the most dense urban tree coverage of any major city in the United States. Atlanta was originally founded as the terminus of a major state-sponsored railroad, but it soon became the convergence point among severa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bronchial Brushing
Bronchial brushing is a procedure in which cells are taken from the inside of the airway mucosa or bronchial lesions through catheter-based brushing under direct visualization or fluoroscopic guidance. Flexible brushes are passed through the bronchoscope, and the bronchial surface is gently abraded to obtain the specimen. Various types of bronchial brush may be used to collect both cellular and microbiological material, using direct vision when collecting from proximal areas of suspicion or fluoroscopic screening when sampling more peripheral sites. A bronchial brushing is used to find cancer and changes in cells that may lead to cancer Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal b .... It can also be used to obtain specimens for microbiologic diagnosis.Joseph Loscalzo. Harrison's Pul ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pneumonia
Pneumonia is an inflammatory condition of the lung primarily affecting the small air sacs known as alveoli. Symptoms typically include some combination of productive or dry cough, chest pain, fever, and difficulty breathing. The severity of the condition is variable. Pneumonia is usually caused by infection with viruses or bacteria, and less commonly by other microorganisms. Identifying the responsible pathogen can be difficult. Diagnosis is often based on symptoms and physical examination. Chest X-rays, blood tests, and culture of the sputum may help confirm the diagnosis. The disease may be classified by where it was acquired, such as community- or hospital-acquired or healthcare-associated pneumonia. Risk factors for pneumonia include cystic fibrosis, chronic obstructive pulmonary disease (COPD), sickle cell disease, asthma, diabetes, heart failure, a history of smoking, a poor ability to cough (such as following a stroke), and a weak immune system. Vaccine ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Journal Of Clinical Microbiology
The ''Journal of Clinical Microbiology'' is a monthly medical journal published by the American Society for Microbiology. The journal was established in 1975. The editor-in-chief is Alexander J. McAdam (Boston Children's Hospital). It is a delayed open access journal full text content is available free after a six-month embargo. Abstracting and indexing The journal is abstracted and indexed in: According to the ''Journal Citation Reports'', the journal has a 2021 impact factor of 11.677 See also *Clinical medicine *Clinical research Clinical research is a branch of healthcare science that determines the safety and effectiveness ( efficacy) of medications, devices, diagnostic products and treatment regimens intended for human use. These may be used for prevention, treat ... * Medical microbiology References External links *{{Official website, http://jcm.asm.org/American Society for Microbiology Delayed open access journals Microbiology journals Monthly journals ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Atypical Pneumonia
Atypical pneumonia, also known as walking pneumonia, is any type of pneumonia not caused by one of the pathogens most commonly associated with the disease. Its clinical presentation contrasts to that of "typical" pneumonia. A variety of microorganisms can cause it. When it develops independently from another disease, it is called primary atypical pneumonia (PAP). The term was introduced in the 1930s and was contrasted with the bacterial pneumonia caused by ''Streptococcus pneumoniae'', at that time the best known and most commonly occurring form of pneumonia. The distinction was historically considered important, as it differentiated those more likely to present with "typical" respiratory symptoms and lobar pneumonia from those more likely to present with "atypical" generalized symptoms (such as fever, headache, sweating and myalgia) and bronchopneumonia. Signs and symptoms Usually the atypical causes also involve atypical symptoms: * No response to common antibiotics such as s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Legionella Pneumophila
''Legionella pneumophila'' is a thin, aerobic, pleomorphic, flagellated, non-spore-forming, Gram-negative bacterium of the genus '' Legionella''. ''L. pneumophila'' is the primary human pathogenic bacterium in this group and is the causative agent of Legionnaires' disease, also known as legionellosis. In nature, ''L. pneumophila'' infects freshwater and soil amoebae of the genera ''Acanthamoeba'' and '' Naegleria''. The mechanism of infection is similar in amoeba and human cells. Characterization ''L. pneumophila'' is a Gram-negative, non-encapsulated, aerobic bacillus with a single, polar flagellum often characterized as being a coccobacillus. It is aerobic and unable to hydrolyse gelatin or produce urease. It is also non- fermentative. ''L. pneumophila'' is neither pigmented nor does it autofluoresce. It is oxidase- and catalase-positive, and produces beta-lactamase. ''L. pneumophila'' colony morphology is gray-white with a textured, cut-glass appearance; it also requi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Legionellales
The Legionellales are an order of Pseudomonadota. Like all Pseudomonadota, they are Gram-negative.George M. Garrity: ''Bergey's Manual of Systematic Bacteriology''. 2. Auflage. Springer, New York, 2005, Volume 2: ''The Proteobacteria, Part B: The Gammaproteobacteria'' They comprise two families, typified by ''Legionella'' and '' Coxiella'', both of which include notable pathogens. For example, Q fever is caused by ''Coxiella burnetii'' and ''Legionella pneumophila'' causes Legionnaires' disease and Pontiac fever. Members of the order ''Legionellales'' can be molecularly distinguished from other Gammaproteobacteria by the presence of four conserved signature indels Conserved signature inserts and deletions (CSIs) in protein sequences provide an important category of molecular markers for understanding phylogenetic relationships. CSIs, brought about by rare genetic changes, provide useful phylogenetic markers ... (CSIs) in the proteins tRNA-guanine(34) transglycosylase, lipoprotei ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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