|
Labdane Diterpene
Labdane is a natural bicyclic diterpene. It forms the structural core for a wide variety of natural products collectively known as ''labdanes'' or ''labdane diterpenes''. The labdanes were so named because the first members of the class were originally obtained from labdanum, a resin derived from the gum rockrose. A variety of biological activities have been determined for labdane diterpenes including antibacterial, antifungal, antiprotozoal, and anti-inflammatory activities. Natural labdanes in tree resin are believed to be the precursors of amber, which polymerise under great pressure. Example labdane derivatives * Forskolin * Galanolactone * Isocupressic acid - is an abortifacient component of ''Cupressus macrocarpa''. * Medigenin *Sclareol * Stemodene See also * Abietane Abietane is an organic compound with the formula C20H36. It is a tricyclic, saturated hydrocarbon with an elaborate stereochemistry. It is a colorless solid. It is of little biochemical interest exce ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diterpene
Diterpenes are a class of terpenes composed of four isoprene units, often with the molecular formula C20H32. They are biosynthesized by plants, animals and fungi via the HMG-CoA reductase pathway, with geranylgeranyl pyrophosphate being a primary intermediate. Diterpenes form the basis for biologically important Chemical compound, compounds such as retinol, retinal, and phytol. Some diterpenes are known to be antimicrobial and anti-inflammatory. Structures As with most terpenes a huge number of potential structures exists, which may be broadly divided according to the number of rings present. Biosynthesis Diterpenes are derived from the addition of one Isopentenyl pyrophosphate, IPP unit to Farnesyl pyrophosphate, FPP to form geranylgeranyl pyrophosphate (GGPP). From GGPP, structural diversity is achieved mainly by two classes of enzymes; the diterpene synthases and Cytochrome P450, cytochromes P450. Several diterpenes are produced by plants and cyanobacteria. GGPP is also t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Natural Product
A natural product is a natural compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life. Natural products can also be prepared by chemical synthesis (both semisynthesis and total synthesis and have played a central role in the development of the field of organic chemistry by providing challenging synthetic targets). The term ''natural product'' has also been extended for commercial purposes to refer to cosmetics, dietary supplements, and foods produced from natural sources without added artificial ingredients. Within the field of organic chemistry, the definition of natural products is usually restricted to organic compounds isolated from natural sources that are produced by the pathways of primary or secondary metabolism. Within the field of medicinal chemistry, the definition is often further restricted to secondary metabolites. Secondary metabolites (or specialized meta ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Labdanum
Labdanum, also called ladanum, ladan, or ladanon, is a sticky brown resin obtained from the shrubs ''Gum rockrose, Cistus ladanifer'' (western Mediterranean) and ''Cistus creticus'' (eastern Mediterranean), species of rockrose. It was historically used in herbal medicine and is still used in the preparation of some perfumes and vermouth, vermouths. History In ancient times, labdanum was collected by combing the beards and thighs of goats and sheep that had grazed on the cistus shrubs. Wooden instruments used were referred to in 19th-century Crete as ''ergastiri''; a ''lambadistrion'' ("labdanum-gatherer") was a kind of rake to which a double row of leathern thongs were fixed instead of teeth. These were used to sweep the shrubs and collect the resin which was later extracted. It was collected by the shepherds and sold to coastal traders. The resin was used as an ingredient for incense, and medicinally to treat colds, coughs, menstrual problems and rheumatism. as cited in Labdan ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cistus Ladanifer
''Cistus ladanifer'' is a species of flowering plant in the family Cistaceae. It is native to the western Mediterranean region. Common names include gum rockrose, labdanum, common gum cistus, and brown-eyed rockrose. Description It is a shrub growing tall and wide. The leaves are evergreen, lanceolate, 3–10 cm long and 1–2 cm broad, dark green above and paler underneath. The flowers are 5–8 cm diameter, with 5 papery white petals, usually with a red to maroon spot at the base, surrounding the yellow stamens and pistils. The whole plant is covered with the sticky exudate of fragrant resin, the source of labdanum, used in herbal medicine and perfumery. Ecology ''C. ladanifer'' is particularly well suited to the Mediterranean climate, standing both long summer droughts and cold weather. It is an extremely aggressive plant which has taken over much of former farmland and grasslands in the mountain regions of central Spain and much of southern Portugal. In Spa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tree
In botany, a tree is a perennial plant with an elongated stem, or trunk, usually supporting branches and leaves. In some usages, the definition of a tree may be narrower, e.g., including only woody plants with secondary growth, only plants that are usable as lumber, or only plants above a specified height. But wider definitions include taller palms, tree ferns, bananas, and bamboos. Trees are not a monophyletic taxonomic group but consist of a wide variety of plant species that have independently evolved a trunk and branches as a way to tower above other plants to compete for sunlight. The majority of tree species are angiosperms or hardwoods; of the rest, many are gymnosperms or softwoods. Trees tend to be long-lived, some trees reaching several thousand years old. Trees evolved around 400 million years ago, and it is estimated that there are around three trillion mature trees in the world currently. A tree typically has many secondary branches supported cle ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Resin
A resin is a solid or highly viscous liquid that can be converted into a polymer. Resins may be biological or synthetic in origin, but are typically harvested from plants. Resins are mixtures of organic compounds, predominantly terpenes. Common resins include amber, hashish, frankincense, myrrh and the animal-derived resin, shellac. Resins are used in varnishes, adhesives, food additives, incenses and perfumes. Resins protect plants from insects and pathogens, and are secreted in response to injury. Resins repel herbivores, insects, and pathogens, while the volatile natural phenol, phenolic compounds may attract benefactors such as predators of insects that attack the plant. Composition Most plant resins are composed of terpenes. Specific components are alpha-Pinene, alpha-pinene, pinene, beta-pinene, carene, delta-3 carene, and sabinene, the monocyclic terpenes limonene and terpinolene, and smaller amounts of the tricyclic sesquiterpenes, longifolene, caryophyllene, and cad ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Amber
Amber is fossilized tree resin. Examples of it have been appreciated for its color and natural beauty since the Neolithic times, and worked as a gemstone since antiquity."Amber" (2004). In Maxine N. Lurie and Marc Mappen (eds.) ''Encyclopedia of New Jersey'', Rutgers University Press, . Amber is used in jewelry and as a healing agent in Traditional medicine, folk medicine. There are five classes of amber, defined on the basis of their chemical constituents. Because it originates as a soft, sticky tree resin, amber sometimes contains animal and plant material as Inclusion (mineral), inclusions. Amber occurring in coal seams is also called resinite, and the term ''ambrite'' is applied to that found specifically within New Zealand coal seams. Etymology The English word ''amber'' derives from Arabic from Middle Persian 𐭠𐭭𐭡𐭫 (''ʾnbl'' /ambar/, “ambergris”) via Medieval Latin, Middle Latin ''ambar'' and Middle French ''ambre''. The word referred to what is n ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Forskolin
Forskolin (coleonol) is a labdane diterpene produced by the plant '' Coleus barbatus'' (blue spur flower). Other names include pashanabhedi, Indian coleus, makandi, HL-362, mao hou qiao rui hua. As with other members of the large diterpene class of plant metabolites, forskolin is derived from geranylgeranyl pyrophosphate (GGPP). Forskolin contains some unique functional elements, including the presence of a tetrahydropyran-derived heterocyclic ring. Forskolin is commonly used in laboratory research to increase levels of cyclic AMP by stimulation of adenylate cyclase. Mechanism of action Forskolin is used in biochemistry experiments to raise levels of cyclic AMP (cAMP) in studies of cell physiology. Forskolin activates the enzyme adenylyl cyclase and increases intracellular levels of cAMP. cAMP is an important second messenger necessary for the proper biological response of cells to hormones and other extracellular signals. It is required for cell communication in the hypothalamus ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Galanolactone
Galanolactone is a diterpenoid lactone first isolated from ginger. It is present in acetone extracts of ginger, and appears to be an antagonist at 5-HT3 receptors Receptor may refer to: *Sensory receptor, in physiology, any neurite structure that, on receiving environmental stimuli, produces an informative nerve impulse *Receptor (biochemistry), in biochemistry, a protein molecule that receives and responds .... References {{reflist Furanones Diterpenes Decalins Epoxides Tetrahydrofurans Spiro compounds ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Isocupressic Acid
Isocupressic acid is a diterpene acid present in a variety of conifer needles. It induces abortion in cattle. It is found in all parts of the ponderosa pine (''Pinus ponderosa''), especially the needles. This gives its toxic and abortifacient effects. It is also present in the lodgepole pine (''P. contorta''), the jeffrey pine (''P. jeffreyi'') and possibly in the monterey pine ''Pinus radiata'' (synonym (taxonomy), syn. ''Pinus insignis''), the Monterey pine, insignis pine or radiata pine, is a species of pine native to the Central Coast (California), Central Coast of California and Mexico (on Guadalupe Island and Ced ... (''P. radiata''). References Pinus Carboxylic acids Diterpenes {{OrganicAcid-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cupressus Macrocarpa
''Hesperocyparis macrocarpa'' also known as ''Cupressus macrocarpa'', or the Monterey cypress is a coniferous tree, and is one of several species of Cupressaceae, cypress trees native to California. The Monterey cypress is found naturally only on the Central Coast (California), Central Coast of California. Due to being a glacial relict, the natural distributional range of the species during modern times is confined to two small relict populations near Carmel-by-the-Sea, California, Carmel, California, at Cypress Point in Pebble Beach, California, Pebble Beach and at Point Lobos. Historically during the peak of the last ice age, Monterey cypress would have likely comprised a much larger forest that extended much further north and south.Axelrod, D. I. (1982)Age and origin of the Monterey endemic area.''Madroño'', ''29''(3), 127–147. Description ''Hesperocyparis macrocarpa'' is a medium-sized coniferous evergreen tree, which often becomes irregular and flat-topped as a resul ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
