Labdane is a natural bicyclic
diterpene. It forms the structural core for a wide variety of
natural product
A natural product is a natural compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life. Natural products can also be prepared by chemical syn ...
s collectively known as ''labdanes'' or ''labdane diterpenes''. The labdanes were so named because the first members of the class were originally obtained from
labdanum, a resin derived from the
gum rockrose.
A variety of biological activities have been determined for labdane diterpenes including antibacterial, antifungal, antiprotozoal, and anti-inflammatory activities.
Example labdane derivatives
*
Forskolin
Forskolin (coleonol) is a labdane diterpene produced by the plant ''Coleus barbatus'' (Blue Spur Flower). Other names include pashanabhedi, Indian coleus, makandi, HL-362, mao hou qiao rui hua. As with other members of the large diterpene class of ...
*
Galanolactone
Galanolactone is a diterpenoid lactone first isolated from ginger. It is present in acetone extracts of ginger, and appears to be an antagonist at 5-HT3 receptors
Receptor may refer to:
*Sensory receptor, in physiology, any structure which, on ...
*
Isocupressic acid
Isocupressic acid is a diterpene acid present in a variety of conifer needles. It induces abortion in cattle.
It is found in all parts of the ponderosa pine (''Pinus ponderosa''), especially the needles. This gives its toxic and abortifacient eff ...
- is an abortifacient component of ''
Cupressus macrocarpa
''Hesperocyparis macrocarpa'' is a coniferous tree. It is commonly known as the Monterey cypress and is one of several species of cypress trees endemic to California.
The Monterey cypress is found naturally only on the Central Coast of Califor ...
''.
*
Medigenin
*
Sclareol
Sclareol is a fragrant chemical compound found in ''Salvia sclarea'', from which it derives its name. It is classified as a bicyclic diterpene alcohol. It is an amber colored solid with a sweet, balsamic scent. Sclareol is also able to kill huma ...
*
Stemodene
See also
*
Abietane
References
{{reflist
Diterpenes
Decalins