Koch–Pasteur Rivalry
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Koch–Pasteur Rivalry
The French Louis Pasteur (1822–1895) and German Robert Koch (1843–1910) are the two greatest figures in medical microbiology and in establishing acceptance of the germ theory of disease (germ theory). In 1882, fueled by national rivalry and a language barrier, the tension between Pasteur and the younger Koch erupted into an acute conflict. Pasteur had already discovered molecular chirality, investigated fermentation, refuted spontaneous generation, inspired Lister's introduction of antisepsis to surgery, introduced pasteurization to France's wine industry, answered the silkworm diseases blighting France's silkworm industry, attenuated a '' Pasteurella'' species of bacteria to develop vaccine to chicken cholera (1879), and introduced anthrax vaccine (1881). Koch had transformed bacteriology by introducing the technique of pure culture, whereby he established the microbial cause of the disease anthrax (1876), had introduced both staining and solid culture plates to bacteri ...
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Louis Pasteur
Louis Pasteur (, ; 27 December 1822 – 28 September 1895) was a French chemist and microbiologist renowned for his discoveries of the principles of vaccination, microbial fermentation and pasteurization, the latter of which was named after him. His research in chemistry led to remarkable breakthroughs in the understanding of the causes and preventions of diseases, which laid down the foundations of hygiene, public health and much of modern medicine. His works are credited to saving millions of lives through the developments of vaccines for rabies and anthrax. He is regarded as one of the founders of modern bacteriology and has been honored as the "father of bacteriology" and the "father of microbiology" (together with Robert Koch; the latter epithet also attributed to Antonie van Leeuwenhoek). Pasteur was responsible for disproving the doctrine of spontaneous generation. Under the auspices of the French Academy of Sciences, his experiment demonstrated that in sterilized ...
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Anthrax
Anthrax is an infection caused by the bacterium '' Bacillus anthracis''. It can occur in four forms: skin, lungs, intestinal, and injection. Symptom onset occurs between one day and more than two months after the infection is contracted. The skin form presents with a small blister with surrounding swelling that often turns into a painless ulcer with a black center. The inhalation form presents with fever, chest pain and shortness of breath. The intestinal form presents with diarrhea (which may contain blood), abdominal pains, nausea and vomiting. The injection form presents with fever and an abscess at the site of drug injection. According to the USA's Centers for Disease Control and Prevention, the first clinical descriptions of cutaneous anthrax were given by Maret in 1752 and Fournier in 1769. Before that anthrax had been described only through historical accounts. The Prussian scientist Robert Koch (1843–1910) was the first to identify ''Bacillus anthracis'' as the bac ...
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Casimir Davaine
Casimir-Joseph Davaine (19 March 1812 – 14 October 1882) was a French physician known for his work in the field of microbiology. He was a native of Saint-Amand-les-Eaux, department of Nord. In 1850, Davaine along with French pathologist Pierre François Olive Rayer, discovered a certain microorganism in the blood of diseased and dying sheep. In the diseased blood, Rayer and Davaine observed the bacillus that is known today as ''Bacillus anthracis'', the causative bacterium of anthrax. Soon afterwards, Rayer published a description of the bacillus in a paper titled, ''Inoculation du sang de rate'' (1850). In 1863, Davaine demonstrated that the bacillus could be directly transmitted from one animal to another. He was able to identify the causative organism, but was unaware of its true etiology. Later on, German microbiologist Robert Koch investigated the etiology of ''Bacillus anthracis'', and discovered its ability to produce "resting spores" that could stay alive in the soil ...
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Robert Koch (6909161361)
Heinrich Hermann Robert Koch ( , ; 11 December 1843 – 27 May 1910) was a German physician and microbiologist. As the discoverer of the specific causative agents of deadly infectious diseases including tuberculosis, cholera (though the bacterium itself was discovered by Filippo Pacini in 1854), and anthrax, he is regarded as one of the main founders of modern bacteriology. As such he is popularly nicknamed the father of microbiology (with Louis Pasteur), and as the father of medical bacteriology. His discovery of the anthrax bacterium (''Bacillus anthracis'') in 1876 is considered as the birth of modern bacteriology. His discoveries directly provided proofs for the germ theory of diseases, and the scientific basis of public health. While working as a private physician, Koch developed many innovative techniques in microbiology. He was the first to use the oil immersion lens, condenser, and microphotography in microscopy. His invention of the bacterial culture method using ag ...
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Medical Science
Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others. Medicine has been practiced since prehistoric times, and for most of this time it was an art (an area of skill and knowledge), frequently having connections to the religious and philosophical beliefs of local culture. For example, a medicine man would apply herbs and say prayers for healing, ...
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University Of Strasbourg
The University of Strasbourg (french: Université de Strasbourg, Unistra) is a public research university located in Strasbourg, Alsace, France, with over 52,000 students and 3,300 researchers. The French university traces its history to the earlier German-language ''Universität Straßburg'', which was founded in 1538, and was divided in the 1970s into three separate institutions: Louis Pasteur University, Marc Bloch University, and Robert Schuman University. On 1 January 2009, the fusion of these three universities reconstituted a united University of Strasbourg. With as many as 19 Nobel laureates, and two Fields Medal winners, the university is ranked among the best in the League of European Research Universities. History The university emerged from a Lutheran humanist German Gymnasium, founded in 1538 by Johannes Sturm in the Free Imperial City of Strassburg. It was transformed to a university in 1621 (german: Universität Straßburg) and elevated to the ranks of ...
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Georg Theodor August Gaffky
Georg Theodor August Gaffky (17 February 1850 – 23 September 1918) was a Hanover-born bacteriologist best known for identifying bacillus salmonella typhi as the cause of typhoid disease in 1884. Early life and career Gaffky's parents were the shipping agent Georg Friedrich Wilhelm Gaffky, and Emma Schumacher. His medical studies at the Friedrich Wilhelm University in Berlin were completed in 1873 after an interruption by the Franco-Prussian War in 1870. His dissertation postulated a relationship between lead poisoning and kidney disease. He worked as an assistant at the Berlin Charité hospital and passed the state medical exams in 1875. He then worked as an army surgeon. Gaffky worked as an assistant to Robert Koch in Berlin. Under Koch's leadership, Gaffky and others developed bacteriological protocols and achieved progress in identifying causes of infectious diseases. Principal discoveries Following Karl Joseph Eberth's description of a bacillus suspected as the cau ...
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Friedrich Loeffler
Friedrich August Johannes Loeffler (; 24 June 18529 April 1915) was a German bacteriologist at the University of Greifswald. Biography He obtained his M.D. degree from the University of Berlin in 1874. He worked with Robert Koch from 1879 to 1884Isaac Asimov, ''Asimov's Biographical Encyclopedia of Science and Technology'', 2nd Revised edition as an assistant in the Imperial Health Office in Berlin. In 1884, he became staff physician at the Friedrich Wilhelm Institute in Berlin, and four years later became professor at the University of Greifswald. His development of original methods of staining rendered an important and lasting service to bacteriology. Early in his career, he began a study of parasitic diseases. Among his discoveries was the organism causing diphtheria (''Corynebacterium diphtheriae'') and the cause of foot-and-mouth disease ( Aphthovirus). His description of the diphtheria bacillus, published in 1884, was the originating cause of an antitoxin treatment. He also ...
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