Karim Nayernia
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Karim Nayernia
Professor Dr. Karim Nayernia () is an Iranian biomedical scientist and a world expert on stem cell biology and Personalized medicine. He carried out pioneering work that has the potential to lead to future therapies for a range of medical conditions such as heart disease, Parkinson's disease and male infertility. His team was the first in the world to isolate a new type of stem cell from adult mouse testes (male sex glands), called spermatagonial stem cells. It was able to show that some of these stem cells, called multipotent adult germline stem cells (maGSCs), turned into heart, muscle, brain and other cells. Prof Nayernia and his team proposed that similar cells could be extracted from men using a simple testicular biopsy. On the basis of these cells, new stem cell techniques could be developed in order to treat a variety of illnesses. In 2018, he developed a new model of medicine called P7MEDICINE. This model is based on predictive molecular diagnostics, preventive medicine, pre ...
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Medical Condition
A disease is a particular abnormal condition that adversely affects the structure or function (biology), function of all or part of an organism and is not immediately due to any external injury. Diseases are often known to be medical conditions that are associated with specific signs and symptoms. A disease may be caused by external factors such as pathogens or by internal dysfunctions. For example, internal dysfunctions of the immune system can produce a variety of different diseases, including various forms of immunodeficiency, hypersensitivity, allergy, allergies, and autoimmune disorders. In humans, ''disease'' is often used more broadly to refer to any condition that causes pain, Abnormality (behavior), dysfunction, distress (medicine), distress, social problems, or death to the person affected, or similar problems for those in contact with the person. In this broader sense, it sometimes includes injury in humans, injuries, disability, disabilities, Disorder (medicine) ...
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Heart Disease
Cardiovascular disease (CVD) is any disease involving the heart or blood vessels. CVDs constitute a class of diseases that includes: coronary artery diseases (e.g. angina pectoris, angina, myocardial infarction, heart attack), heart failure, hypertensive heart disease, rheumatic heart disease, cardiomyopathy, arrhythmia, congenital heart disease, valvular heart disease, carditis, aortic aneurysms, peripheral artery disease, Thrombosis, thromboembolic disease, and venous thrombosis. The underlying mechanisms vary depending on the disease. It is estimated that dietary risk factors are associated with 53% of CVD deaths. Coronary artery disease, stroke, and peripheral artery disease involve atherosclerosis. This may be caused by hypertension, high blood pressure, tobacco smoking, smoking, diabetes mellitus, lack of physical exercise, exercise, obesity, hypercholesterolaemia, high blood cholesterol, poor diet, excessive alcoholic beverage, alcohol consumption, and poor sleep, amo ...
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Parkinson's Disease
Parkinson's disease (PD), or simply Parkinson's, is a neurodegenerative disease primarily of the central nervous system, affecting both motor system, motor and non-motor systems. Symptoms typically develop gradually and non-motor issues become more prevalent as the disease progresses. The motor symptoms are collectively called parkinsonism and include tremors, bradykinesia, spasticity, rigidity as well as postural instability (i.e., difficulty maintaining balance). Non-motor symptoms develop later in the disease and include behavior change (individual), behavioral changes or mental disorder, neuropsychiatric problems such as sleep abnormalities, psychosis, anosmia, and mood swings. Most Parkinson's disease cases are idiopathic disease, idiopathic, though contributing factors have been identified. Pathophysiology involves progressive nerve cell death, degeneration of nerve cells in the substantia nigra, a midbrain region that provides dopamine to the basal ganglia, a system invo ...
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Testicle
A testicle or testis ( testes) is the gonad in all male bilaterians, including humans, and is Homology (biology), homologous to the ovary in females. Its primary functions are the production of sperm and the secretion of Androgen, androgens, primarily testosterone. The release of testosterone is regulated by luteinizing hormone (LH) from the anterior pituitary gland. Sperm production is controlled by follicle-stimulating hormone (FSH) from the anterior pituitary gland and by testosterone produced within the gonads. Structure Appearance Males have two testicles of similar size contained within the scrotum, which is an extension of the abdominal wall. Scrotal asymmetry, in which one testicle extends farther down into the scrotum than the other, is common. This is because of the differences in the vasculature's anatomy. For 85% of men, the right testis hangs lower than the left one. Measurement and volume The volume of the testicle can be estimated by palpating it and compari ...
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Stem Cell
In multicellular organisms, stem cells are undifferentiated or partially differentiated cells that can change into various types of cells and proliferate indefinitely to produce more of the same stem cell. They are the earliest type of cell in a cell lineage. They are found in both embryonic and adult organisms, but they have slightly different properties in each. They are usually distinguished from progenitor cells, which cannot divide indefinitely, and precursor or blast cells, which are usually committed to differentiating into one cell type. In mammals, roughly 50 to 150 cells make up the inner cell mass during the blastocyst stage of embryonic development, around days 5–14. These have stem-cell capability. '' In vivo'', they eventually differentiate into all of the body's cell types (making them pluripotent). This process starts with the differentiation into the three germ layers – the ectoderm, mesoderm and endoderm – at the gastrulation stage. However, whe ...
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Alumnus
Alumni (: alumnus () or alumna ()) are former students or graduates of a school, college, or university. The feminine plural alumnae is sometimes used for groups of women, and alums (: alum) or alumns (: alumn) as gender-neutral alternatives. The word comes from Latin, meaning nurslings, pupils or foster children, derived from "to nourish". The term is not synonymous with "graduates": people can be alumni without graduating, e.g. Burt Reynolds was an alumnus of Florida State University but did not graduate. The term is sometimes used to refer to former employees, former members of an organization, former contributors, or former inmates. Etymology The Latin noun means "foster son" or "pupil". It is derived from the Latin verb "to nourish". Separate, but from the same root, is the adjective "nourishing", found in the phrase '' alma mater'', a title for a person's home university. Usage in Roman law In Latin, is a legal term (Roman law) to describe a child placed in foste ...
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University Of Göttingen
The University of Göttingen, officially the Georg August University of Göttingen (, commonly referred to as Georgia Augusta), is a Public university, public research university in the city of Göttingen, Lower Saxony, Germany. Founded in 1734 by George II of Great Britain, George II, King of Great Britain and Electorate of Hanover, Elector of Hanover, it began instruction in 1737 and is recognized as the oldest university in Lower Saxony. Recognized for its historic and traditional significance, the university has affiliations with 47 Nobel Prize winners by its own count. Previously backed by the German Universities Excellence Initiative, the University of Göttingen is a member of the U15 (German Universities), U15 Group of major German research universities, underscoring its strong research profile. It is also a part of prominent international and European academic networks such as Guild of European Research-Intensive Universities, The Guild, the ENLIGHT alliance, and the Hek ...
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Newcastle University
Newcastle University (legally the University of Newcastle upon Tyne) is a public research university based in Newcastle upon Tyne, England. It has overseas campuses in Singapore and Malaysia. The university is a red brick university and a member of the Russell Group, an association of research-intensive UK universities. The university's history began with the School of Medicine and Surgery (later the College of Medicine), established in Newcastle in 1834, and the College of Physical Science (later renamed Armstrong College), founded in 1871. These two colleges came to form the larger division of the federal University of Durham, with the Durham Colleges forming the other. The Newcastle colleges merged to form King's College in 1937. In 1963, following an Act of Parliament, King's College became the University of Newcastle upon Tyne. The university is subdivided into three faculties: the Faculty of Humanities and Social Sciences; the Faculty of Medical Sciences; and the Fac ...
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Institute Of Human Genetics
An institute is an organizational body created for a certain purpose. They are often research organisations (research institutes) created to do research on specific topics, or can also be a professional body. In some countries, institutes can be part of a university or other institutions of higher education, either as a group of departments or an autonomous educational institution without a traditional university status such as a "university institute", or institute of technology. In some countries, such as South Korea and India, private schools are sometimes referred to as institutes; also, in Spain, secondary schools are referred to as institutes. Historically, in some countries, institutes were educational units imparting vocational training and often incorporating libraries, also known as mechanics' institutes. The word "institute" comes from the Latin word ''institutum'' ("facility" or "habit"), in turn derived from ''instituere'' ("build", "create", "raise" or "educat ...
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Iranian Medical Researchers
Iranian () may refer to: * Something of, from, or related to Iran ** Iranian diaspora, Iranians living outside Iran ** Iranian architecture, architecture of Iran and parts of the rest of West Asia ** Iranian cuisine, cooking traditions and practices Other uses * Iranian peoples, the speakers of the Iranian languages. The term Iranic peoples is also used for this term to distinguish the pan-ethnic term from Iranian, used for the people of Iran * Iranian languages, a branch of the Indo-Iranian languages * Iranian.com, also known as ''The Iranian'' and ''The Iranian Times'' See also * Persian (other) * Iranians (other) * Languages of Iran * Ethnicities in Iran * Demographics of Iran * Indo-Iranian languages * Irani (other) * List of Iranians This is an alphabetic list of notable people from Iran or its historical predecessors. In the news * Ali Khamenei, supreme leader of Iran * Ebrahim Raisi, former president of Iran, former Chief Justice of Iran. ...
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Academics Of Newcastle University
Academic means of or related to an academy, an institution learning. Academic or academics may also refer to: * Academic staff, or faculty, teachers or research staff * school of philosophers associated with the Platonic Academy in ancient Greece * The Academic, Irish indie rock band * "Academic", song by New Order from the 2015 album ''Music Complete'' Other uses *Academia (other) *Academy (other) *Faculty (other) *Scholar A scholar is a person who is a researcher or has expertise in an academic discipline. A scholar can also be an academic, who works as a professor, teacher, or researcher at a university. An academic usually holds an advanced degree or a termina ...
, a person who is a researcher or has expertise in an academic discipline {{Disambiguation ...
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