Professor Dr. Karim Nayernia () is an Iranian biomedical scientist and a world expert on stem cell biology and Personalized medicine. He carried out pioneering work that has the potential to lead to future therapies for a range of

medical condition A disease is a particular abnormal condition that adversely affects the structure or function (biology), function of all or part of an organism and is not immediately due to any external injury. Diseases are often known to be medical condi ...

s such as

heart disease Cardiovascular disease (CVD) is any disease involving the heart or blood vessels. CVDs constitute a class of diseases that includes: coronary artery diseases (e.g. angina pectoris, angina, myocardial infarction, heart attack), heart failure, ...

Parkinson's disease Parkinson's disease (PD), or simply Parkinson's, is a neurodegenerative disease primarily of the central nervous system, affecting both motor system, motor and non-motor systems. Symptoms typically develop gradually and non-motor issues become ...

and male infertility. His team was the first in the world to isolate a new type of stem cell from adult mouse

testes A testicle or testis ( testes) is the gonad in all male bilaterians, including humans, and is homologous to the ovary in females. Its primary functions are the production of sperm and the secretion of androgens, primarily testosterone. The ...

(male sex glands), called spermatagonial

stem cell In multicellular organisms, stem cells are undifferentiated or partially differentiated cells that can change into various types of cells and proliferate indefinitely to produce more of the same stem cell. They are the earliest type of cell ...

s. It was able to show that some of these stem cells, called multipotent adult germline stem cells (maGSCs), turned into heart, muscle, brain and other cells. Prof Nayernia and his team proposed that similar cells could be extracted from men using a simple testicular biopsy. On the basis of these cells, new stem cell techniques could be developed in order to treat a variety of illnesses. In 2018, he developed a new model of medicine called P7MEDICINE. This model is based on predictive molecular diagnostics, preventive medicine, precision medicine, personalized medical artificial intelligence, personalized treatment, personalized monitoring, and personalized patient management.

Academic career

Karim Nayernia is an

alumnus Alumni (: alumnus () or alumna ()) are former students or graduates of a school, college, or university. The feminine plural alumnae is sometimes used for groups of women, and alums (: alum) or alumns (: alumn) as gender-neutral alternatives. Th ...

of the

University of Göttingen The University of Göttingen, officially the Georg August University of Göttingen (, commonly referred to as Georgia Augusta), is a Public university, public research university in the city of Göttingen, Lower Saxony, Germany. Founded in 1734 ...

, where he had defended his dissertation in 1993. He worked at the university until 2006, when he started to work at the

Newcastle University Newcastle University (legally the University of Newcastle upon Tyne) is a public research university based in Newcastle upon Tyne, England. It has overseas campuses in Singapore and Malaysia. The university is a red brick university and a mem ...

. In 2003, he got the professorship (Habilitation) in Molecular Human Genetics from Medical Faculty of Georg-August University in Göttingen and in 2006 Professorship for Stem Cell Biology from the Newcastle University Institute of Human Genetics.
In 2009, he created human sperm-like cells from male stem cells in the laboratory for the first time. Previously, in 2006, he used sperm created from embryonic stem cells to impregnate mice. The mice produced seven pups, although one died and the other six had health problems. In 2010, he discovered a new marker for detection of breast cancer stem cells. This findings define this novel marker and its effector signaling pathways as key factors in the proliferation and survival of breast cancer stem cells. He is working now on projects in the field of personalized medicine and director and founder of the International Center for Personalized Medicine (p7medicine.com) and European Center of personalized Medicine (ECPM) focusing on personalized medicine and stem cell technologies, gene and cell therapy. He is Director of International Stem Cell Academy which was established in 2016 (stemcell-academy.com) focusing on education of new scientists in the field of stem cell sciences at international level. He is currently director of International Center for Personalized Medicine in Düsseldorf/Germany (www.icpm.center) and Director of International Stem Cell Academy (www.stemcell-academy.com).

References

External links

www.icpm.center

* ttps://www.newscientist.com/article/dn11601-bone-stem-cells-turned-into-primitive-sperm-cells/ Newscientist.com* *
The Guardian articleThe Guardian articleBBC article
{{DEFAULTSORT:Nayernia, Karim Iranian medical researchers Academics of Newcastle University Living people Year of birth missing (living people) Biomedical engineers