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Joseph Erlanger
Joseph Erlanger (January 5, 1874 – December 5, 1965) was an American physiologist who is best known for his contributions to the field of neuroscience. Together with Herbert Spencer Gasser, he identified several varieties of nerve fiber and established the relationship between action potential velocity and fiber diameter. They were awarded the Nobel Prize in Physiology or Medicine in 1944 for these achievements. Biography Erlanger was born on January 5, 1874, in San Francisco, California. His family was Jewish and his parents both immigrated from the Kingdom of Württemberg, Germany and met in California during the Gold Rush. Joseph was the sixth of seven children born to the couple. He completed his Bachelor of Science in Chemistry from the University of California, Berkeley in 1895. He then completed his M.D. in 1899 from the Johns Hopkins School of Medicine in Baltimore, Maryland, where he finished second in his class. Upon graduating, Erlanger interned at Johns Hopkins H ...
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San Francisco, California
San Francisco, officially the City and County of San Francisco, is a commercial, Financial District, San Francisco, financial, and Culture of San Francisco, cultural center of Northern California. With a population of 827,526 residents as of 2024, San Francisco is the List of California cities by population, fourth-most populous city in the U.S. state of California and the List of United States cities by population, 17th-most populous in the United States. San Francisco has a land area of at the upper end of the San Francisco Peninsula and is the County statistics of the United States, fifth-most densely populated U.S. county. Among U.S. cities proper with over 250,000 residents, San Francisco is ranked first by per capita income and sixth by aggregate income as of 2023. San Francisco anchors the Metropolitan statistical area#United States, 13th-most populous metropolitan statistical area in the U.S., with almost 4.6 million residents in 2023. The larger San Francisco Bay Area ...
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Bachelor Of Science
A Bachelor of Science (BS, BSc, B.S., B.Sc., SB, or ScB; from the Latin ') is a bachelor's degree that is awarded for programs that generally last three to five years. The first university to admit a student to the degree of Bachelor of Science was the University of London in 1860. In the United States, the Lawrence Scientific School first conferred the degree in 1851, followed by the University of Michigan in 1855. Nathaniel Shaler, who was Harvard's Dean of Sciences, wrote in a private letter that "the degree of Bachelor of Science came to be introduced into our system through the influence of Louis Agassiz, who had much to do in shaping the plans of this School." Whether Bachelor of Science or Bachelor of Arts degrees are awarded in particular subjects varies between universities. For example, an economics student may graduate as a Bachelor of Arts in one university but as a Bachelor of Science in another, and occasionally, both options are offered. Some universities follo ...
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Madison, Wisconsin
Madison is the List of capitals in the United States, capital city of the U.S. state of Wisconsin. It is the List of municipalities in Wisconsin by population, second-most populous city in the state, with a population of 269,840 at the 2020 United States census, 2020 census. The Madison metropolitan area had 680,796 residents. Centrally located on an isthmus between Lakes Lake Mendota, Mendota and Lake Monona, Monona, the vicinity also encompass Lakes Lake Wingra, Wingra, Lake Kegonsa, Kegonsa and Lake Waubesa, Waubesa. Madison was founded in 1836 and is named after American Founding Fathers of the United States, Founding Father and President James Madison. It is the county seat of Dane County. As the state capital, Madison is home to government chambers including the Wisconsin State Capitol building. It is also home to the University of Wisconsin–Madison, the flagship campus of the University of Wisconsin System. Major companies in the area include American Family Insurance, ...
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William Henry Howell
William Henry Howell (February 20, 1860 – February 6, 1945) was an American physiologist. He pioneered the use of heparin as a blood anti-coagulant. Early life William Henry Howell was born on February 20, 1860, in Baltimore, Maryland. He graduated from the Baltimore City College high school in 1878. He was educated at Johns Hopkins University, from which he graduated in 1881 with a Bachelor of Arts. He taught at the University of Michigan and at Harvard before becoming professor at Johns Hopkins in 1893. He received a Doctor of Medicine from the University of Michigan in 1890. He graduated with a PhD from Johns Hopkins in 1894. He also studied at Trinity College and the University of Edinburgh. Career Howell served as associate professor of physiology at Johns Hopkins in 1888 and 1889. He served as a full professor at the University of Michigan from 1889 to 1892. He then served as associate professor of physiology at Harvard Medical School from 1892 to 1893. He then moved ba ...
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Brachial Artery
The brachial artery is the major blood vessel of the (upper) arm. It is the continuation of the axillary artery beyond the lower margin of teres major muscle. It continues down the ventral surface of the arm until it reaches the cubital fossa at the Elbow-joint, elbow. It then divides into the radial artery, radial and ulnar artery, ulnar artery, arteries which run down the forearm. In some individuals, the bifurcation occurs much earlier and the ulnar and radial arteries extend through the upper arm. The pulse of the brachial artery is palpation, palpable on the anterior aspect of the elbow, medial to the tendon of the Biceps brachii muscle, biceps, and, with the use of a stethoscope and sphygmomanometer (blood pressure cuff), often used to measure the blood pressure. The brachial artery is closely related to the median nerve; in proximal regions, the median nerve is immediately lateral to the brachial artery. Distally, the median nerve crosses the medial side of the brachial ...
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Blood Pressure
Blood pressure (BP) is the pressure of Circulatory system, circulating blood against the walls of blood vessels. Most of this pressure results from the heart pumping blood through the circulatory system. When used without qualification, the term "blood pressure" refers to the pressure in a brachial artery, where it is most commonly measured. Blood pressure is usually expressed in terms of the systolic pressure (maximum pressure during one Cardiac cycle, heartbeat) over diastolic pressure (minimum pressure between two heartbeats) in the cardiac cycle. It is measured in Millimetre of mercury, millimetres of mercury (mmHg) above the surrounding atmospheric pressure, or in Pascal (unit), kilopascals (kPa). The difference between the systolic and diastolic pressures is known as pulse pressure, while the average pressure during a cardiac cycle is known as mean arterial pressure. Blood pressure is one of the vital signs—together with respiratory rate, heart rate, Oxygen saturation (me ...
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Sphygmomanometer
A sphygmomanometer ( ), also known as a blood pressure monitor, blood pressure machine, or blood pressure gauge, is a device used to measure blood pressure, composed of an inflatable cuff to collapse and then release the artery under the cuff in a controlled manner, and a mercury or aneroid manometer to measure the pressure. Manual sphygmomanometers are used with a stethoscope when using the auscultatory technique. A sphygmomanometer consists of an inflatable cuff, a measuring unit (the mercury manometer, or aneroid gauge), and a mechanism for inflation which may be a manually operated bulb and valve or a pump operated electrically. Etymology The word ''sphygmomanometer'' uses the combining form of '' sphygmo-'' + '' manometer''. The roots involved are as follows: Greek ''sphygmos'' "pulse", plus the scientific term '' manometer'' (from French ''manomètre''), i.e. "pressure meter", itself coined from ''manos'' "thin, sparse", and ''metron'' "measure". Most sphygmom ...
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Arthur D
Arthur is a masculine given name of uncertain etymology. Its popularity derives from it being the name of the legendary hero King Arthur. A common spelling variant used in many Slavic, Romance, and Germanic languages is Artur. In Spanish and Italian it is Arturo. Etymology The earliest attestation of the name Arthur is in the early 9th century Welsh-Latin text ''Historia Brittonum'', where it refers to a circa 5th century Romano-British general who fought against the invading Saxons, and who later gave rise to the famous King Arthur of medieval legend and literature. A possible earlier mention of the same man is to be found in the epic Welsh poem '' Y Gododdin'' by Aneirin, which some scholars assign to the late 6th century, though this is still a matter of debate and the poem only survives in a late 13th century manuscript entitled the Book of Aneirin. A 9th-century Breton landowner named Arthur witnessed several charters collected in the '' Cartulary of Redon''. The Irish bo ...
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Ventricle (heart)
A ventricle is one of two large chambers located toward the bottom of the heart that collect and expel blood towards the peripheral beds within the body and lungs. The blood pumped by a ventricle is supplied by an atrium, an adjacent chamber in the upper heart that is smaller than a ventricle. Interventricular means between the ventricles (for example the interventricular septum), while intraventricular means within one ventricle (for example an intraventricular block). In a four-chambered heart, such as that in humans, there are two ventricles that operate in a double circulatory system: the right ventricle pumps blood into the pulmonary circulation to the lungs, and the left ventricle pumps blood into the systemic circulation through the aorta. Structure Ventricles have thicker walls than atria and generate higher blood pressures. The physiological load on the ventricles requiring pumping of blood throughout the body and lungs is much greater than the pressure generated by ...
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Atrium (heart)
The atrium (; : atria) is one of the two Heart#Chambers, upper chambers in the heart that receives blood from the circulatory system. The blood in the atria is pumped into the Ventricle (heart), heart ventricles through the atrioventricular valve, atrioventricular mitral valve, mitral and tricuspid valve, tricuspid heart valves. There are two atria in the human heart – the left atrium receives blood from the pulmonary circulation, and the right atrium receives blood from the venae cavae of the systemic circulation. During the cardiac cycle, the atria receive blood while relaxed in diastole, then contract in systole to move blood to the ventricles. Each atrium is roughly cube-shaped except for an ear-shaped projection called an atrial appendage, previously known as an auricle. All animals with a closed circulatory system have at least one atrium. The atrium was formerly called the 'auricle'. That term is still used to describe this chamber in some other animals, such as the ''Mo ...
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Cardiology
Cardiology () is the study of the heart. Cardiology is a branch of medicine that deals with disorders of the heart and the cardiovascular system. The field includes medical diagnosis and treatment of congenital heart defects, coronary artery disease, heart failure, valvular heart disease, and electrophysiology. Physicians who specialize in this field of medicine are called cardiologists, a sub-specialty of internal medicine. Pediatric cardiologists are pediatricians who specialize in cardiology. Physicians who specialize in cardiac surgery are called cardiothoracic surgeons or cardiac surgeons, a specialty of general surgery. Specializations All cardiologists in the branch of medicine study the disorders of the heart, but the study of adult and child heart disorders each require different training pathways. Therefore, an adult cardiologist (often simply called "cardiologist") is inadequately trained to take care of children, and pediatric cardiologists are not trained to treat ...
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William Osler
Sir William Osler, 1st Baronet, (; July 12, 1849 – December 29, 1919) was a Canadian physician and one of the "Big Four" founding professors of Johns Hopkins Hospital. Osler created the first Residency (medicine), residency program for specialty training of physicians. He has frequently been described as the ''Father of Modern Medicine'' and one of the "greatest diagnosticians ever to wield a stethoscope". In addition to being a physician he was a bibliophile, historian, author, and renowned practical joker. He was passionate about medical libraries and medical history, having founded the History of Medicine Society (formally "section"), at the Royal Society of Medicine, London. He was also instrumental in founding the Medical Library Association of Great Britain and Ireland, and the (North American) Association of Medical Librarians (later the Medical Library Association) along with three other people, including Margaret Ridley Charlton, Margaret Charlton, the medical librari ...
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