Joseph Burchenal
Joseph Holland Burchenal (December 21, 1912 – March 8, 2006) was an American oncologist, and a winner of the 1972 Albert Lasker Award for Medical Research for his work on developing a chemotherapy for Burkitt's lymphoma.Staff, ASCO. February 24, 201Oncology Luminaries: Dr. Joseph Burchenal (1912-2006)/ref> His research with George Hitchings and Gertrude Elion led to the creation of the leukemia treatment mercaptopurine. He worked at Memorial Sloan Kettering Cancer Center and was a member of the presidential panel that initiated the U.S. federal government's War on Cancer. Burchenal died in Hanover, New Hampshire Hanover is a New England town, town located along the Connecticut River in Grafton County, New Hampshire, United States. As of the 2020 United States census, 2020 census, its population was 11,870. The town is home to the Ivy League university ... on March 8, 2006. He was 93 years old.Jeremy Pearce for the ''New York Times''. March 16, 200Dr. Joseph H. Burchenal ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Oncologist
Oncology is a branch of medicine that deals with the study, treatment, diagnosis, and prevention of cancer. A medical professional who practices oncology is an ''oncologist''. The name's etymological origin is the Greek word ὄγκος (''ónkos''), meaning "tumor", "volume" or "mass". Oncology is focused on the diagnosis of cancer in a person, therapy (e.g., surgery, chemotherapy, radiotherapy and other modalities), monitoring of patients after treatment, palliative care of people with advanced-stage cancers, ethical questions surrounding cancer care, screening of patients, and the study of cancer treatments through clinical research. An oncologist typically focuses on a specialty area in cancer treatment, such as surgery, radiation, gynecologic oncology, geriatric oncology, pediatric oncology, and various organ-specific disciplines (breast, brain, liver, among others). The expertise of an oncologist is applied when cancer is suspected, diagnosed with, or treated from ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Lasker Award
In 1945 Albert Lasker and Mary Woodard Lasker created the Lasker Awards. Every year since then the award has been given to the living person considered to have made the greatest contribution to medical science or who has demonstrated public service on behalf of medicine. They are administered by the Lasker Foundation. The Lasker is sometimes referred to as "America's Nobels". The Lasker Awards have gained a reputation for identifying future winners of the Nobel Prize. Eighty-six Lasker laureates have received the Nobel Prize, including 32 in the last two decades. Claire Pomeroy is the current president of the Lasker Foundation. Award The award is given in four branches of medical science: # Albert Lasker Basic Medical Research Award # Lasker–DeBakey Clinical Medical Research Award # Lasker–Bloomberg Public Service Award (Renamed in 2011 from Mary Woodard Lasker Public Service Award. Renamed in 2000 from Albert Lasker Public Service Award.) # '' Lasker–Koshland Speci ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Burkitt's Lymphoma
Burkitt's lymphoma is a cancer of the lymphatic system, particularly B lymphocytes found in the germinal center. It is named after Denis Parsons Burkitt, the Irish surgeon who first described the disease in 1958 while working in equatorial Africa. It is a highly aggressive form of cancer which often, but not always, manifests after a person develops acquired immunodeficiency from infection with Epstein–Barr virus, Epstein-Barr Virus or HIV, Human Immunodeficiency Virus (HIV). The overall cure rate for Burkitt's lymphoma in developed countries is about 90%. Burkitt's lymphoma is uncommon in adults, in whom it has a worse prognosis. Classification Burkitt lymphoma can be divided into three main clinical variants: the endemic, the Sporadic cancer, sporadic, and the immunodeficiency-associated variants. By morphology (biology), morphology (i.e., microscopic appearance), immunophenotype, and genetics, the variants of Burkitt lymphoma are alike. * The endemic variant (also called " ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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George Hitchings
George Herbert Hitchings (April 18, 1905 – February 27, 1998) was an American medical doctor who shared the 1988 Nobel Prize in Physiology or Medicine with Sir James Black and Gertrude Elion "for their discoveries of important principles for drug treatment", Hitchings specifically for his work on chemotherapy. Education and early life Hitchings was born in Hoquiam, Washington, in 1905, and grew up there, in Berkeley, California, San Diego, Bellingham, Washington, and Seattle. He graduated from Seattle's Franklin High School, where he was salutatorian, in 1923, and from there went to the University of Washington, from which he graduated with a degree in chemistry ''cum laude'' in 1927, after having been elected to Phi Beta Kappa as a junior the year before. That summer, he worked at the university's Puget Sound Biological Station at Friday Harbor on San Juan Islandbr> and received a master's degree the next year for his thesis based on that work. From the University of Was ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Gertrude Elion
Gertrude "Trudy" Belle Elion (January 23, 1918 – February 21, 1999) was an American biochemist and pharmacologist, who shared the 1988 Nobel Prize in Physiology or Medicine with George H. Hitchings and Sir James Black for their use of innovative methods of rational drug design for the development of new drugs. This new method focused on understanding the target of the drug rather than simply using trial-and-error. Her work led to the creation of the anti-retroviral drug AZT, which was the first drug widely used against AIDS. Her well known works also include the development of the first immunosuppressive drug, azathioprine, used to fight rejection in organ transplants, and the first successful antiviral drug, acyclovir (ACV), used in the treatment of herpes infection. Early life and education Elion was born in New York City on January 23, 1918, to parents Robert Elion, a Lithuanian Jewish immigrant and a dentist, and Bertha Cohen, a Polish Jewish immigrant. Her family ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Mercaptopurine
Mercaptopurine (6-MP), sold under the brand name Purinethol among others, is a medication used for cancer and autoimmune diseases. Specifically it is used to treat acute lymphocytic leukemia (ALL), acute promyelocytic leukemia (APL), Crohn's disease, and ulcerative colitis. For acute lymphocytic leukemia it is generally used with methotrexate. It is taken orally. Common side effects include bone marrow suppression, liver toxicity, vomiting, and loss of appetite. Other serious side effects include an increased risk of future cancer and pancreatitis. Those with a genetic deficiency in thiopurine S-methyltransferase are at higher risk of side effects. Use in pregnancy may harm the baby. Mercaptopurine is in the thiopurine and antimetabolite family of medications. Mercaptopurine was approved for medical use in the United States in 1953. It is on the World Health Organization's List of Essential Medicines. Medical uses It is used to treat acute lymphocytic leukemia, Crohn's ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Memorial Sloan Kettering Cancer Center
Memorial Sloan Kettering Cancer Center (MSK or MSKCC) is a cancer treatment and research institution in Manhattan in New York City. MSKCC is one of 72 National Cancer Institute– designated Comprehensive Cancer Centers. Its main campus is located at 1275 York Avenue between 67th and 68th Streets in Manhattan. It was formed in 1980 from the merger of the ''Memorial Hospital for the Treatment of Cancer and Allied Diseases'', founded in 1884, and the adjacent ''Sloan-Kettering Institute for Cancer Research'', founded in 1945. The two medical entities had formally coordinated their operations since 1960. History Early history of Memorial Hospital (1884–1934) The hospital was founded in its original building on the Upper West Side of Manhattan in 1884 as ''New York Cancer Hospital'' by a group that included John Jacob Astor III and his wife Charlotte. The hospital appointed as an attending surgeon William B. Coley, who pioneered an early form of immunotherapy to erad ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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War On Cancer
The "war on cancer" was launched in 1971 by President Richard Nixon to find a cure for cancer by increased research. The goals were to improve the understanding of cancer biology and to develop more effective cancer treatments, such as targeted drug therapies. The aim of such efforts is to eradicate cancer as a major cause of death. Despite significant progress in the treatment of certain forms of cancer (such as childhood leukemia), cancer in general remains a major cause of death half a century after this war on cancer began, leading to a perceived lack of progress and to new legislation aimed at augmenting the original National Cancer Act of 1971. New research directions, in part based on the results of the Human Genome Project, hold promise for a better understanding of the genetic factors underlying cancer, and the development of new diagnostics, therapies, preventive measures, and early detection ability. However, targeting cancer proteins can be difficult, as a prote ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Hanover, New Hampshire
Hanover is a New England town, town located along the Connecticut River in Grafton County, New Hampshire, United States. As of the 2020 United States census, 2020 census, its population was 11,870. The town is home to the Ivy League university Dartmouth College, the U.S. Army Corps of Engineers Cold Regions Research and Engineering Laboratory, and Hanover High School (New Hampshire), Hanover High School. The Appalachian Trail crosses the town, connecting with a number of trails and nature preserves. Most of the population resides in the Hanover (CDP), New Hampshire, Hanover census-designated place (CDP)—the main village of the town. Located at the junctions of New Hampshire routes New Hampshire Route 10, 10, New Hampshire Route 10A, 10A, and New Hampshire Route 120, 120, the Hanover CDP recorded a population of 9,078 people at the 2020 census. The town is part of the Lebanon–Claremont micropolitan area and also contains the smaller villages of Etna, New Hampshire, Etna and ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Elizabeth Burchenal
Flora Elizabeth Burchenal (October 1875 – November 21, 1959) was an American educator and the first president of the American Folk Dance Society when it was founded in 1916. Journalist Ida Tarbell described Burchenal as "one of the 50 living women who have done the most for the welfare of the United States." Early life and education Burchenal was born in Richmond, Indiana, the daughter of Charles H. Burchenal and Mary Elizabeth Day Burchenal. Her father was a lawyer and a judge. She graduated from Earlham College in 1896, and pursued further studies at the Sargent School of Physical Education in Boston. Career Burchenal taught physical education classes at Teachers College, Columbia University from 1903 to 1905. She was executive secretary of the Girls' Branch of the Public School Athletic League of New York from 1906 to 1916. In 1909, she was appointed by the New York City Department of Education as inspector of athletics, promoting and overseeing dance instruction in the cit ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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1912 Births
This year is notable for Sinking of the Titanic, the sinking of the ''Titanic'', which occurred on April 15. In Albania, this leap year runs with only 353 days as the country achieved switching from the Julian to Gregorian Calendar by skipping 13 days. Friday, 30 November ''(Julian Calendar)'' immediately turned Saturday, 14 December 1912 ''(in the Gregorian Calendar)''. Events January * January 1 – The Republic of China (1912–49), Republic of China is established. * January 5 – The Prague Conference (6th All-Russian Conference of the Russian Social Democratic Labour Party) opens. * January 6 ** German Geophysics, geophysicist Alfred Wegener first presents his theory of continental drift. ** New Mexico becomes the 47th U.S. state. * January 8 – The African National Congress is founded as the South African Native National Congress, at the Waaihoek Wesleyan Church in Bloemfontein, to promote improved rights for Black people, black South Africans, with Joh ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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2006 Deaths
This is a list of lists of deaths of notable people, organized by year. New deaths articles are added to their respective month (e.g., Deaths in ) and then linked below. 2025 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 1986 Earlier years ''Deaths in years earlier than this can usually be found in the main articles of the years.'' See also * Lists of deaths by day * Deaths by year (category) {{DEFAULTSORT:deaths by year ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |