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John Neoptolemos
John P. Neoptolemos is a British surgeon and professor who specialised in pancreas research. His specific areas of research are diagnosis, biological predictors of treatment response and therapies of pancreatic cancer as well as acute, chronic, and hereditary pancreatitis. Neoptolemos was a British Department of Health Platinum Award holder from 2004. He was elected a Member of the Academia Europaea in 2019. Early life, education, career Neoptolemos was born in Pano Zodhia, Cyprus and raised in London. He graduated from the University of Cambridge (Churchill College) (1970-1973), and at Guy's Hospital, London (1973-1976). Neoptolemos completed his academic and clinical training in Leicester under the tutelage of Professor Sir Peter Bell, being awarded a Doctorate in Medicine in 1986 for his thesis "Effect of surgery on monocyte function in patients with colorectal cancer". During surgical training in Ulm he met Markus Büchler, together setting up the European Study for ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Birmingham
The University of Birmingham (informally Birmingham University) is a Public university, public research university in Birmingham, England. It received its royal charter in 1900 as a successor to Queen's College, Birmingham (founded in 1825 as the William Sands Cox, Birmingham School of Medicine and Surgery), and Mason Science College (established in 1875 by Sir Josiah Mason), making it the first English red brick university, civic or 'red brick' university to receive its own royal charter, and the first English Collegiate university, unitary university. It is a founding member of both the Russell Group of British research universities and the international network of research universities, Universitas 21. The student population includes undergraduate and postgraduate students (), which is the List of universities in the United Kingdom by enrollment, largest in the UK (out of ). The annual income of the university for 2023–24 was £926 million of which £205.2 mil ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Department Of Health And Social Care
The Department of Health and Social Care (DHSC) is a ministerial department of the Government of the United Kingdom. It is responsible for government policy on health and adult social care matters in England, along with a few elements of the same matters which are not otherwise devolved to the Scottish Government, Welsh Government or Northern Ireland Executive. It oversees the English National Health Service (NHS). The department is led by the Secretary of State for Health and Social Care with three ministers of state and three parliamentary under-secretaries of state. The department develops policies and guidelines to improve the quality of care and to meet patient expectations. It carries out some of its work through arms-length bodies (ALBs), including executive non-departmental public bodies such as NHS England and the NHS Digital, and executive agencies such as the UK Health Security Agency and the Medicines and Healthcare products Regulatory Agency (MHRA). The ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hereditary Pancreatitis
Hereditary pancreatitis (HP) is an inflammation of the pancreas due to genetic causes. It was first described in 1952 by Comfort and Steinberg but it was not until 1996 that Whitcomb ''et al'' isolated the first responsible mutation in the trypsinogen gene ('' PRSS1'') on the long arm of chromosome seven (''7q35''). The term "hereditary pancreatitis" is used when a genetic biomarker is identified, and "familial pancreatitis" otherwise. Presentation HP is characterised by attacks of epigastric pain, which are often associated with nausea and vomiting. Symptoms may start shortly after birth but onset varies periodically, with some patients not exhibiting symptoms until adulthood. There is usually progression to chronic pancreatitis with endocrine and exocrine failure and a mortally increased risk of pancreatic cancer. Lifetime risk of cancer has been variously calculated as 35–54% to the age of 75 years and screening for early pancreatic cancer is being offered to HP sufferers on ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chronic Pancreatitis
Chronic pancreatitis is a long-standing inflammation of the pancreas that alters the organ's normal structure and functions. It can present as episodes of acute inflammation in a previously injured pancreas, or as chronic damage with persistent pain or malabsorption. It is a disease process characterized by irreversible damage to the pancreas as distinct from reversible changes in acute pancreatitis. Tobacco smoke and alcohol misuse are two of the most frequently implicated causes, and the two risk factors are thought to have a synergistic effect with regards to the development of chronic pancreatitis. Chronic pancreatitis is a risk factor for the development of pancreatic cancer. Signs and symptoms * Upper abdominal pain: Upper abdominal pain which increases after drinking or eating, lessens when fasting or sitting and leaning forward. Some people may not suffer pain. * Nausea and vomiting * Steatorrhea: Frequent, oily, foul-smelling bowel movements. Damage to the pancreas can ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Acute Pancreatitis
Acute pancreatitis (AP) is a sudden inflammation of the pancreas. Causes include a gallstone impacted in the common bile duct or the pancreatic duct, heavy alcohol use, systemic disease, trauma, elevated calcium levels, hypertriglyceridemia (with triglycerides usually being very elevated, over 1000 mg/dL), certain medications, hereditary causes and, in children, mumps. Acute pancreatitis may be a single event, it may be recurrent, or it may progress to chronic pancreatitis and/or pancreatic failure (the term pancreatic dysfunction includes cases of acute or chronic pancreatitis where the pancreas is measurably damaged, even if it has not failed). In all cases of acute pancreatitis, early intravenous fluid hydration and early enteral (nutrition delivered to the gut, either by mouth or via a feeding tube) feeding are associated with lower mortality and complications. Mild cases are usually successfully treated with conservative measures such as hospitalization with intrav ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pancreatic Cancer
Pancreatic cancer arises when cell (biology), cells in the pancreas, a glandular organ behind the stomach, begin to multiply out of control and form a Neoplasm, mass. These cancerous cells have the malignant, ability to invade other parts of the body. A number of types of pancreatic cancer are known. The most common, pancreatic adenocarcinoma, accounts for about 90% of cases, and the term "pancreatic cancer" is sometimes used to refer only to that type. These adenocarcinomas start within the part of the pancreas that makes digestive enzymes. Several other types of cancer, which collectively represent the majority of the non-adenocarcinomas, can also arise from these cells. About 1–2% of cases of pancreatic cancer are neuroendocrine tumors, which arise from the hormone-producing neuroendocrine cell, cells of the pancreas. These are generally less aggressive than pancreatic adenocarcinoma. Signs and symptoms of the most-common form of pancreatic cancer may include jaundice, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pancreas
The pancreas (plural pancreases, or pancreata) is an Organ (anatomy), organ of the Digestion, digestive system and endocrine system of vertebrates. In humans, it is located in the abdominal cavity, abdomen behind the stomach and functions as a gland. The pancreas is a mixed or heterocrine gland, i.e., it has both an endocrine and a digestive exocrine function. Ninety-nine percent of the pancreas is exocrine and 1% is endocrine. As an endocrine gland, it functions mostly to regulate blood sugar levels, secreting the hormones insulin, glucagon, somatostatin and pancreatic polypeptide. As a part of the digestive system, it functions as an exocrine gland secreting pancreatic juice into the duodenum through the pancreatic duct. This juice contains bicarbonate, which neutralizes acid entering the duodenum from the stomach; and digestive enzymes, which break down carbohydrates, proteins and lipids, fats in food entering the duodenum from the stomach. Inflammation of the pancreas is kno ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Professor
Professor (commonly abbreviated as Prof.) is an Academy, academic rank at university, universities and other tertiary education, post-secondary education and research institutions in most countries. Literally, ''professor'' derives from Latin as a 'person who professes'. Professors are usually experts in their field and teachers of the highest rank. In most systems of List of academic ranks, academic ranks, "professor" as an unqualified title refers only to the most senior academic position, sometimes informally known as "full professor". In some countries and institutions, the word ''professor'' is also used in titles of lower ranks such as associate professor and assistant professor; this is particularly the case in the United States, where the unqualified word is also used colloquially to refer to associate and assistant professors as well, and often to instructors or lecturers. Professors often conduct original research and commonly teach undergraduate, Postgraduate educa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Surgeon
In medicine, a surgeon is a medical doctor who performs surgery. Even though there are different traditions in different times and places, a modern surgeon is a licensed physician and received the same medical training as physicians before specializing in surgery. In some countries and jurisdictions, the title of 'surgeon' is restricted to maintain the integrity of the craft group in the medical profession. A specialist regarded as a legally recognized surgeon includes podiatry, dentistry, and veterinary medicine. It is estimated that surgeons perform over 300 million surgical procedures globally each year. History The first person to document a surgery was the 6th century BC Indian physician-surgeon, Sushruta. He specialized in cosmetic plastic surgery and even documented an open rhinoplasty procedure.Papel, Ira D. and Frodel, John (2008) ''Facial Plastic and Reconstructive Surgery''. Thieme Medical Pub. His Masterpiece, magnum opus ''Suśruta-saṃhitā'' is one of the m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Hospital Heidelberg
University Hospital Heidelberg () is a university hospital in Heidelberg, Germany and is with 1,991 beds one of the largest medical centers in the country. It is closely linked to Heidelberg University Medical School (Heidelberg University Faculty of Medicine) which was founded in 1388 and is thus the oldest within the Federal Republic of Germany. Patient care Over 1 million patients per year are treated at the University Hospital Heidelberg. The hospital is especially renowned for the treatment of cancer. A recent innovation in the care of cancer patient is the foundation of the National Center of Tumor Diseases (NCT) in cooperation with German Cancer Research Center (DKFZ). The goal of NCT is an interdisciplinary collaboration between various clinical and basic science disciplines and the fast implementation of new and innovative therapeutic procedures. A good example for the Heidelberg's leading position in innovative cancer research and treatment is HIT (heavy ion therapy ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Heidelberg
Heidelberg University, officially the Ruprecht Karl University of Heidelberg (; ), is a public university, public research university in Heidelberg, Baden-Württemberg, Germany. Founded in 1386 on instruction of Pope Urban VI, Heidelberg is List of universities in Germany#Universities by date of establishment, Germany's oldest university and one of the List of oldest universities in continuous operation, world's oldest surviving universities; it was the third university established in the Holy Roman Empire after Charles University, Prague (1347) and University of Vienna, Vienna (1365). Since 1899, it has been a coeducational institution. Heidelberg is one of the most prestigious universities in Germany. It is a German Excellence Universities, German Excellence University, part of the U15 (German universities), U15, as well as a founding member of the League of European Research Universities and the Coimbra Group. The university consists of twelve Faculty (division), faculties and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
