John D. Aitchison
   HOME





John D. Aitchison
John D Aitchison is a Canadian American molecular cell biologist, systems cell biologist, and academic. He serves as a Principal Investigator at Seattle Children's Research Institute and Professor in the Department of Pediatrics, an Affiliate/Adjunct Professor in the Department of Biochemistry, at the University of Washington (UW). Serving as an Affiliate Professor at the Institute for Systems Biology (ISB), he is also an adjunct professor at University of Alberta (UAlberta). Aitchison's research interests include using systems biology to understand complex biological phenomena. His work has spanned from basic cell biology, using yeast as a model system, focusing on understanding molecular mechanisms of nuclear transport and peroxisome biogenesis and function to host-pathogen interactions, studying how viruses and other pathogens influence cellular function. His research lab also developed and applied systems biology approaches to reveal fundamental insights into cell biology, ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Molecular Biology
Molecular biology is a branch of biology that seeks to understand the molecule, molecular basis of biological activity in and between Cell (biology), cells, including biomolecule, biomolecular synthesis, modification, mechanisms, and interactions. Though cells and other microscopic structures had been observed in living organisms as early as the 18th century, a detailed understanding of the mechanisms and interactions governing their behavior did not emerge until the 20th century, when technologies used in physics and chemistry had advanced sufficiently to permit their application in the biological sciences. The term 'molecular biology' was first used in 1945 by the English physicist William Astbury, who described it as an approach focused on discerning the underpinnings of biological phenomena—i.e. uncovering the physical and chemical structures and properties of biological molecules, as well as their interactions with other molecules and how these interactions explain observ ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Nuclear Transport
Nuclear transport refers to the mechanisms by which molecules move across the nuclear membrane of a cell. The entry and exit of large molecules from the cell nucleus is tightly controlled by the nuclear pore complexes (NPCs). Although small molecules can enter the nucleus without regulation, macromolecules such as RNA and proteins require association with transport factors known as nuclear transport receptors, like karyopherins called importins to enter the nucleus and exportins to exit. Nuclear import Protein that must be imported to the nucleus from the cytoplasm carry nuclear localization signals (NLS) that are bound by importins. An NLS is a sequence of amino acids that acts as a tag. They are most commonly hydrophilic sequences containing lysine and arginine residues, although diverse NLS sequences have been documented. Proteins, transfer RNA, and assembled ribosomal subunits are exported from the nucleus due to association with exportins, which bind signaling sequences calle ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


McMaster University Alumni
McMaster may refer to: * Mount McMaster, in Enderby Land, East Antarctica * McMaster (surname) * McMaster School, a building of the University of South Carolina * McMaster University, a university in Hamilton, Ontario, Canada See also * McMaster-Carr, industrial supply company * MacMaster (surname) {{Distinguish, McMaster (surname) MacMaster (also Macmaster) is a Scottish surname, and may refer to: People * Allan MacMaster (born 1974) Canadian politician * Buddy MacMaster (1924–2014), Canadian musician, uncle of Natalie MacMaster * D ... * McMasters (surname) {{disambiguation. ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Academic Staff Of The University Of Alberta
An academy (Attic Greek: Ἀκαδήμεια; Koine Greek Ἀκαδημία) is an institution of tertiary education. The name traces back to Plato's school of philosophy, founded approximately 386 BC at Akademia, a sanctuary of Athena, the goddess of wisdom and skill, north of Athens, Greece. The Royal Spanish Academy defines academy as scientific, literary or artistic society established with public authority and as a teaching establishment, public or private, of a professional, artistic, technical or simply practical nature. Etymology The word comes from the ''Academy'' in ancient Greece, which derives from the Athenian hero, ''Akademos''. Outside the city walls of Athens, the gymnasium was made famous by Plato as a center of learning. The sacred space, dedicated to the goddess of wisdom, Athena, had formerly been an olive grove, hence the expression "the groves of Academe". In these gardens, the philosopher Plato conversed with followers. Plato developed his sessions ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

University Of Washington Faculty
A university () is an institution of tertiary education and research which awards academic degrees in several academic disciplines. ''University'' is derived from the Latin phrase , which roughly means "community of teachers and scholars". Universities typically offer both undergraduate and postgraduate programs. The first universities in Europe were established by Catholic monks. The University of Bologna (), Italy, which was founded in 1088, is the first university in the sense of: *being a high degree-awarding institute. *using the word (which was coined at its foundation). *having independence from the ecclesiastic schools and issuing secular as well as non-secular degrees (with teaching conducted by both clergy and non-clergy): grammar, rhetoric, logic, theology, canon law and notarial law.Hunt Janin: "The university in medieval life, 1179–1499", McFarland, 2008, , p. 55f.de Ridder-Symoens, Hilde''A History of the University in Europe: Volume 1, Universities in the Midd ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


21st-century American Academics
File:1st century collage.png, From top left, clockwise: Jesus is Crucifixion of Jesus, crucified by Roman authorities in Judaea (17th century painting). Four different men (Galba, Otho, Vitellius, and Vespasian) Year of the Four Emperors, claim the title of Emperor within the span of a year; The Great Fire of Rome (18th-century painting) sees the destruction of two-thirds of the city, precipitating the empire's Persecution of Christians in the Roman Empire#Neronian persecution, first persecution against Christians, who are blamed for the disaster; The Roman Colosseum is built and Inaugural games of the Flavian Amphitheatre, holds its inaugural games; Roman forces Siege of Jerusalem (70 CE), besiege Jerusalem during the First Jewish–Roman War (19th-century painting); The Trưng sisters Trung sisters' rebellion, lead a rebellion against the Chinese Han dynasty (anachronistic depiction); Boudica, queen of the British Iceni leads Boudican revolt, a rebellion against Rome (19th-century ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Molecular Biologists
Molecular biology is a branch of biology that seeks to understand the molecule, molecular basis of biological activity in and between Cell (biology), cells, including biomolecule, biomolecular synthesis, modification, mechanisms, and interactions. Though cells and other microscopic structures had been observed in living organisms as early as the 18th century, a detailed understanding of the mechanisms and interactions governing their behavior did not emerge until the 20th century, when technologies used in physics and chemistry had advanced sufficiently to permit their application in the biological sciences. The term 'molecular biology' was first used in 1945 by the English physicist William Astbury, who described it as an approach focused on discerning the underpinnings of biological phenomena—i.e. uncovering the physical and chemical structures and properties of biological molecules, as well as their interactions with other molecules and how these interactions explain observ ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


Center For Infectious Disease Research
The Center for Infectious Disease Research (CIDR) is housed at the Medical College of Wisconsin (MCW) in Milwaukee. The CIDR houses a BSL3 laboratory. As of 2021, its focus is "on understanding the molecular mechanisms of pathogenesis related to infection with all types of microorganisms, viruses, fungi or parasites." History The CIDR was established in 2002 as the Center for Bioterrorism and Infectious Diseases (CBID). The name was changed to its current status in 2010. Over a three-year period in the early 2010s, a total of four notifiable accidents involving dermal punctures. As of 2015, the MCW operated two BSL-3 laboratories both on the main campus in Wauwatosa. In May 2015, it was reported that "MCW's lab is registered with the federal government to work with the Gram-negative bacteria Bacteria (; : bacterium) are ubiquitous, mostly free-living organisms often consisting of one Cell (biology), biological cell. They constitute a large domain (biology), domain o ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  




Günter Blobel
Günter Blobel (; May 21, 1936 – February 18, 2018) was a Silesian German and American biologist and 1999 Nobel Prize laureate in Physiology for the discovery that proteins have intrinsic signals that govern their transport and localization in the cell. Education and early life Günter Blobel was born in Waltersdorf in the Prussian Province of Lower Silesia, then located in eastern Germany. In January 1945 his family fled from native Silesia to Dresden to escape from the advancing Red Army. During the bombing of Dresden, Blobel, then 8, stayed with his family at a relative's farm to the west of the city. After the war, Blobel grew up and attended gymnasium in the Saxon town of Freiberg. He studied medicine and graduated from the University of Tübingen in 1960. After two years service in a medical internship, he moved to Madison, Wisconsin, following an older brother, enrolling in the University of Wisconsin–Madison and, joining the lab of Van R. Potter for his graduate w ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Rockefeller University
The Rockefeller University is a Private university, private Medical research, biomedical Research university, research and graduate-only university in New York City, New York. It focuses primarily on the biological and medical sciences and provides doctoral and postdoctoral education. It is Carnegie Classification of Institutions of Higher Education, classified as a "Special Focus – Research Institution". Rockefeller is the oldest biomedical research institute in the United States. The university is located on the Upper East Side of Manhattan, between 63rd and 68th streets on York Avenue / Sutton Place, York Avenue. Richard P. Lifton became the university's eleventh president on September 1, 2016. The Rockefeller University Press publishes the ''Journal of Experimental Medicine'', the ''Journal of Cell Biology'', and ''The Journal of General Physiology''. In 2018, the faculty included 82 tenured and tenure-track members, including 37 members of the National Academy of Scienc ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


Infectious Diseases (medical Specialty)
Infectious diseases (ID), also known as infectiology, is a medical specialty dealing with the diagnosis and treatment of infections. An infectious diseases specialist's practice consists of managing nosocomial ( healthcare-acquired) infections or community-acquired infections. An ID specialist investigates and determines the cause of a disease (bacteria, virus, parasite, fungus or prions). Once the cause is known, an ID specialist can then run various tests to determine the best drug to treat the disease. While infectious diseases have always been around, the infectious disease specialty did not exist until the late 1900s after scientists and physicians in the 19th century paved the way with research on the sources of infectious disease and the development of vaccines. Scope Infectious diseases specialists typically serve as consultants to other physicians in cases of complex infections, and often manage patients with HIV/AIDS and other forms of immunodeficiency. Although many c ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]