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Joel Elkes
Joel Elkes (12 November 1913 – 30 October 2015) was a leading medical researcher specialising in the chemistry of the brain. He qualified as a physician in London and later became a medical researcher who published the first double-blind scientific trial on chlorpromazine to treat schizophrenia. He is regarded as the father of modern neuropsychopharmacology and directed the first experimental psychiatric Uffculme Clinic in Birmingham, UK. He was responsible for the setting up of international organisations and university departments to further the investigation of the effects of psychopharmacy. He spent the latter part of his career endeavouring to bring higher levels of humanity, compassion and ethics to medical training. Early life Elkes was born of Jewish parents Elkhanan and Miriam in the city of Königsberg (now Kaliningrad). His father served in the Russian Army as a medical officer during the Russian Revolution of 1905 and World War I. The family fled to Kovno (now Kaunas) ...
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Königsberg
Königsberg (; ; ; ; ; ; , ) is the historic Germany, German and Prussian name of the city now called Kaliningrad, Russia. The city was founded in 1255 on the site of the small Old Prussians, Old Prussian settlement ''Twangste'' by the Teutonic Knights during the Northern Crusades, Baltic Crusades. It was named in honour of King Ottokar II of Bohemia, who led a campaign against the pagan Old Prussians, a Baltic tribe. A Baltic Sea, Baltic port city, it successively became the capital of the State of the Teutonic Order, the Duchy of Prussia and the provinces of East Prussia and Province of Prussia, Prussia. Königsberg remained the coronation city of the Prussian monarchy from 1701 onwards, though the capital was Berlin. From the thirteenth to the twentieth centuries on, the inhabitants spoke predominantly German language, German, although the city also had a profound influence upon the Lithuanian and Polish cultures. It was a publishing center of Lutheranism, Lutheran literatu ...
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American College Of Neuropsychopharmacology
Founded in 1961, the American College of Neuropsychopharmacology (ACNP) is a professional organization of leading brain and behavior scientists. The principal functions of the College are research and education. Their goals in research are to offer investigators an opportunity for cross-disciplinary communication and to promote the application of various scientific disciplines to the study of the brain's effect on behavior, with a focus on mental illness of all forms.  Their educational goals are to encourage young scientists to enter research careers in neuropsychopharmacology and to develop and provide accurate information about behavioral disorders and their pharmacological treatment. Organization The college is an honorary society. Members are selected primarily on the basis of their original research contributions to the broad field of neuroscience.  The membership of the college is drawn from scientists in multiple fields including behavioral pharmacology, neuroimaging, ...
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Myelin
Myelin Sheath ( ) is a lipid-rich material that in most vertebrates surrounds the axons of neurons to insulate them and increase the rate at which electrical impulses (called action potentials) pass along the axon. The myelinated axon can be likened to an electrical wire (the axon) with insulating material (myelin) around it. However, unlike the plastic covering on an electrical wire, myelin does not form a single long sheath over the entire length of the axon. Myelin ensheaths part of an axon known as an internodal segment, in multiple myelin layers of a tightly regulated internodal length. The ensheathed segments are separated at regular short unmyelinated intervals, called nodes of Ranvier. Each node of Ranvier is around one micrometre long. Nodes of Ranvier enable a much faster rate of conduction known as saltatory conduction where the action potential recharges at each node to jump over to the next node, and so on till it reaches the axon terminal. At the terminal the ...
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Lipoprotein
A lipoprotein is a biochemical assembly whose primary function is to transport hydrophobic lipid (also known as fat) molecules in water, as in blood plasma or other extracellular fluids. They consist of a triglyceride and cholesterol center, surrounded by a phospholipid outer shell, with the hydrophilic portions oriented outward toward the surrounding water and lipophilic portions oriented inward toward the lipid center. A special kind of protein, called apolipoprotein, is embedded in the outer shell, both stabilising the complex and giving it a functional identity that determines its role. Plasma lipoprotein particles are commonly divided into five main classes, based on size, lipid composition, and apolipoprotein content. They are, in increasing size order: HDL, LDL, IDL, VLDL and chylomicrons. Subgroups of these plasma particles are primary drivers or modulators of atherosclerosis. Many enzymes, transporters, structural proteins, antigens, adhesins, and toxins are some ...
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University Of Birmingham
The University of Birmingham (informally Birmingham University) is a Public university, public research university in Birmingham, England. It received its royal charter in 1900 as a successor to Queen's College, Birmingham (founded in 1825 as the William Sands Cox, Birmingham School of Medicine and Surgery), and Mason Science College (established in 1875 by Sir Josiah Mason), making it the first English red brick university, civic or 'red brick' university to receive its own royal charter, and the first English Collegiate university, unitary university. It is a founding member of both the Russell Group of British research universities and the international network of research universities, Universitas 21. The student population includes undergraduate and postgraduate students (), which is the List of universities in the United Kingdom by enrollment, largest in the UK (out of ). The annual income of the university for 2023–24 was £926 million of which £205.2 mil ...
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The Second World War
World War II or the Second World War (1 September 1939 – 2 September 1945) was a global conflict between two coalitions: the Allies and the Axis powers. Nearly all of the world's countries participated, with many nations mobilising all resources in pursuit of total war. Tanks and aircraft played major roles, enabling the strategic bombing of cities and delivery of the first and only nuclear weapons ever used in war. World War II is the deadliest conflict in history, causing the death of 70 to 85 million people, more than half of whom were civilians. Millions died in genocides, including the Holocaust, and by massacres, starvation, and disease. After the Allied victory, Germany, Austria, Japan, and Korea were occupied, and German and Japanese leaders were tried for war crimes. The causes of World War II included unresolved tensions in the aftermath of World War I and the rise of fascism in Europe and militarism in Japan. Key events preceding the war included Ja ...
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The Journal Of Physiology
''The Journal of Physiology'' is a semi-monthly peer-reviewed scientific journal that was established in 1878 and is published by Wiley-Blackwell on behalf of The Physiological Society. It covers research on all aspects of physiology, with an emphasis on human and mammalian physiology, including work at the molecular level, at the level of the cell membrane, single cells, tissues or organs, and systems physiology. The full archive back to 1878 up to issues published 12 months from the current date is freely available online. The editor-in-chief is Kim Barrett (University of California, Davis). According to the ''Journal Citation Reports'', the journal has a 2022 impact factor of 5.5. History The journal was first published in 1878 and edited by Michael Foster. In 1893–1894 Foster's colleague John Newport Langley took over as editor. Langley remained the proprietor and editor until his death in 1925, when The Physiological Society bought the journal from his widow. Charles ...
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The Daily Telegraph
''The Daily Telegraph'', known online and elsewhere as ''The Telegraph'', is a British daily broadsheet conservative newspaper published in London by Telegraph Media Group and distributed in the United Kingdom and internationally. It was founded by Arthur B. Sleigh in 1855 as ''The Daily Telegraph and Courier''. ''The Telegraph'' is considered a newspaper of record in the UK. The paper's motto, "Was, is, and will be", was included in its emblem which was used for over a century starting in 1858. In 2013, ''The Daily Telegraph'' and ''The Sunday Telegraph'', which started in 1961, were merged, although the latter retains its own editor. It is politically conservative and supports the Conservative Party (UK), Conservative Party. It was moderately Liberalism, liberal politically before the late 1870s.Dictionary of Nineteenth Century Journalismp 159 ''The Telegraph'' has had a number of news scoops, including the outbreak of World War II by rookie reporter Clare Hollingworth, desc ...
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Aleck Bourne
Aleck William Bourne (4 June 1886 – 30 December 1974) was a prominent British gynaecologist and writer, known for his 1938 trial, a landmark case, in which he asked to be arrested for performing a termination of pregnancy on a 14-year-old rape victim. He was subsequently charged with procuring an illegal abortion but was acquitted. He later became an anti-abortion activist. Early life and career Born in 1886, the only son of W. C. Bourne in Barnet, Bourne was educated at Rydal School and at Downing College, Cambridge where, in 1908, he received a first class Natural Science Tripos. Granted a senior university scholarship, he entered St Mary's Hospital in 1908 and he qualified as an MRCS, LRCP in 1910. He obtained an MB, BCh, (Cambridge), and a FRCS (England) the following year). From 1910 to 1914 he was a resident and subsequently held other appointments at St Mary's, Queen Charlotte's, and the Samaritan hospitals. In 1912, he married Bessie Hayward, the eldest daughter ...
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Alexander Fleming
Sir Alexander Fleming (6 August 1881 – 11 March 1955) was a Scottish physician and microbiologist, best known for discovering the world's first broadly effective antibiotic substance, which he named penicillin. His discovery in 1928 of what was later named benzylpenicillin (or penicillin G) from the mould ''Penicillium rubens'' has been described as the "single greatest victory ever achieved over disease". For this discovery, he shared the Nobel Prize in Physiology or Medicine in 1945 with Howard Florey and Ernst Chain. He also discovered the enzyme lysozyme from his nasal discharge in 1922, and along with it a bacterium he named ''Micrococcus lysodeikticus'', later renamed ''Micrococcus luteus''. Fleming was Knight Bachelor, knighted for his scientific achievements in 1944. In 1999, he was named in ''Time (magazine), Time'' magazine's list of the Time 100: The Most Important People of the Century, 100 Most Important People of the 20th century. In 2002, he was chosen in th ...
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Almroth Wright
Sir Almroth Edward Wright (10 August 1861 – 30 April 1947) was an English bacteriologist and immunologist. He is notable for developing a system of anti-typhoid fever inoculation, recognizing early on that antibiotics would create resistant bacteria, and being a strong advocate for preventive medicine. Biography Wright was born at Middleton Tyas, near Richmond, North Yorkshire into a family of mixed Anglo-Irish and Swedish descent.Michael Worboys, 'Wright, Sir Almroth Edward (1861–1947)', He was the son of Reverend Charles Henry Hamilton Wright, deacon of Middleton Tyas, who later served in Belfast, Dublin, and Liverpool and managed the Protestant Reformation Society. His mother, Ebba Almroth, was the daughter of , Governor of the Swedish Royal Mint in Stockholm.Sir Charles Hagberg Wright (obituary)''. The Times, 7 March 1940. His younger brother Charles Theodore Hagberg Wright became the librarian of the London Library. In 1882, he graduated from Trinity Colleg ...
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Charles Wilson, 1st Baron Moran
Charles McMoran Wilson, 1st Baron Moran, MC, PRCP (10 November 1882 – 12 April 1977) was personal doctor to Winston Churchill from 1940 until the latter's death in 1965. His book ''The Struggle for Survival'' revealed much about Churchill's physical and psychological state, possibly including clinical depression, while coping with the strain of high office. Background Moran was born in Skipton, Yorkshire, younger son and youngest of three children of John Forsythe Wilson, a physician and general practitioner from Northern Ireland, and his wife Mary Jane, daughter of the Reverend John Julius Hannah, a Presbyterian minister of Clogher. He was educated at Pocklington Grammar School then studied medicine at St Mary's Hospital Medical School, now the Imperial College School of Medicine, graduating with a MBBS in 1908. He took his MD degree in 1913 at the same medical school. As a student he played in the college rugby fifteen as well as at county level for Middlesex. He enlist ...
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