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Alexander Fleming
Sir Alexander Fleming (6 August 1881 – 11 March 1955) was a Scottish physician and microbiologist, best known for discovering the world's first broadly effective antibiotic substance, which he named penicillin. His discovery in 1928 of what was later named benzylpenicillin (or penicillin G) from the mould ''Penicillium rubens'' has been described as the "single greatest victory ever achieved over disease". For this discovery, he shared the Nobel Prize in Physiology or Medicine in 1945 with Howard Florey and Ernst Chain. He also discovered the enzyme lysozyme from his nasal discharge in 1922, and along with it a bacterium he named ''Micrococcus lysodeikticus'', later renamed ''Micrococcus luteus''. Fleming was Knight Bachelor, knighted for his scientific achievements in 1944. In 1999, he was named in ''Time (magazine), Time'' magazine's list of the Time 100: The Most Important People of the Century, 100 Most Important People of the 20th century. In 2002, he was chosen in th ...
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Darvel
Darvel (, ) is a town in East Ayrshire, Scotland. It is at the eastern end of the Loudoun, Irvine Valley and is sometimes referred to as "The Lang Toon" (). The town's Latin motto, , means "Not for ourselves, but for others". History Prehistory and archaeology Archaeological excavations and surveys, between 2003 and 2007, by Glasgow University Archaeological Research Division (GUARD) in advance of the extension to the Loudoun Hill Quarry, found that people had been living in the area between the Mesolithic and the Late Iron Age Scotland, Late Iron Age periods. In the earliest periods the area was covered by woodlands and those were probably still undisturbed. An additional excavation, in 2007, found a rare late medieval farmstead. The pottery and Radiocarbon dating, radiocarbon dates indicate that the farm was occupied in the 14th–15th centuries. It is thought that this site belonged to the farm of Newton, which was first documented in the late 14th century within the pa ...
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Benzylpenicillin
Benzylpenicillin, also known as penicillin G (PenG) or BENPEN, is an antibiotic used to treat a number of bacterial infections. This includes pneumonia, strep throat, syphilis, necrotizing enterocolitis, diphtheria, gas gangrene, leptospirosis, cellulitis, and tetanus. It is not a first-line agent for pneumococcal meningitis. Due to benzylpenicillin's limited bioavailability for oral medications, it is generally taken as an injection in the form of a sodium, potassium, benzathine, or procaine salt. Benzylpenicillin is given by injection into a vein or muscle. Two long-acting forms benzathine benzylpenicillin and procaine benzylpenicillin are available for use by injection into a muscle only. Side effects include diarrhea, seizures, and allergic reactions including anaphylaxis. When used to treat syphilis or Lyme disease a reaction known as Jarisch–Herxheimer may occur. It is not recommended in those with a history of penicillin allergy. Use during pregnancy is gene ...
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William Wallace
Sir William Wallace (, ; Norman French: ; 23 August 1305) was a Scottish knight who became one of the main leaders during the First War of Scottish Independence. Along with Andrew Moray, Wallace defeated an English army at the Battle of Stirling Bridge in September 1297. He was appointed Guardian of Scotland and served until his defeat at the Battle of Falkirk in July 1298. In August 1305, Wallace was captured in Robroyston, near Glasgow, and handed over to King Edward I of England, who had him hanged, drawn and quartered for high treason and crimes against English civilians. Since his death, Wallace has obtained a legendary status beyond his homeland. He is the protagonist of Blind Harry's 15th-century epic poem '' The Wallace'' and the subject of literary works by Jane Porter and Sir Walter Scott, and of the Academy Award-winning film ''Braveheart''. Background William Wallace was a member of the lesser nobility, but little is definitely known of his family history ...
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Robert Burns
Robert Burns (25 January 1759 – 21 July 1796), also known familiarly as Rabbie Burns, was a Scottish poet and lyricist. He is widely regarded as the List of national poets, national poet of Scotland and is celebrated worldwide. He is the best known of the poets who have written in the Scots language, although much of his writing is in a "light Central Scots, Scots dialect" of English, accessible to an audience beyond Scotland. He also wrote in standard English, and in these writings his political or civil commentary is often at its bluntest. He is regarded as a pioneer of the Romanticism, Romantic movement, and after his death he became a great source of inspiration to the founders of both liberalism and socialism, and a cultural icon in Scotland and among the Scottish diaspora around the world. Celebration of his life and work became almost a national charismatic cult during the 19th and 20th centuries, and his influence has long been strong on Scottish literature. In 2009 ...
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STV (TV Channel)
STV is a free-to-air public broadcast television channel owned and operated by the STV Group. It is made up of the Central Scotland and Northern Scotland ITV public broadcaster licences, formerly known as Scottish Television (now legally STV Central Ltd) and Grampian Television (now legally STV North Ltd) respectively. The STV brand refers to the on-air name used by Scottish Television for much of its history - notably in the 1970s and early 1980s. This brand remained in conversational use amongst the local public afterwards. The modern STV brand was adopted on Tuesday 30 May 2006 replacing both franchises' previous identities. The sense of continuity in the name was demonstrated when STV celebrated its 60th birthday in 2017, with special programmes broadcast on STV itself and STV2. STV is now the only part of the Channel 3 network that is not owned by ITV plc. The station does not carry ITV1 branding or show ITV1's network presentation except during news broadcasts, ...
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100 Greatest Britons
''100 Greatest Britons'' is a television series that was broadcast by the BBC in 2002. It was based on a television poll conducted to determine who the British people at that time considered the greatest Britons in history. The series included individual programmes featuring the top ten, with viewers having further opportunity to vote after each programme. It concluded with a debate and final determination of the ranking of the top ten. Although many living people were included among the top 100, all of the top ten were deceased. Poll The poll resulted in nominees including Guy Fawkes, who was executed because of his role in the plot to blow up the Parliament of England; Oliver Cromwell, who created a republican British state (the Commonwealth of England, Scotland, and Ireland); Richard III, suspected of murdering his nephews; James Connolly, an Irish nationalist and socialist who was executed by the Crown due to his part in the 1916 Easter Rising; Thomas Paine, who wrote ag ...
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The Most Important People Of The Century
''Time'' 100: The Most Important People of the Century is a compilation of the 20th century's 100 most influential people, published in ''Time'' magazine across five issues in 1998 and 1999. The idea for such a list started on February 1, 1998, with a debate at a symposium in Hanoi, Vietnam. The panel participants were former ''CBS Evening News'' anchor Dan Rather, historian Doris Kearns Goodwin, former New York governor Mario Cuomo, then–Stanford Provost Condoleezza Rice, publisher Irving Kristol, and ''Time'' managing editor Walter Isaacson. In a separate issue on December 31, 1999, ''Time'' recognized Albert Einstein as the Person of the Century. List categories ''Time'' cited 20 selections in each of five categories: Leaders & Revolutionaries, Artists & Entertainers, Builders & Titans, Scientists & Thinkers, and Heroes & Icons. Person of the Century Of the 100 chosen, Albert Einstein was chosen as the Person of the Century, on the grounds that he was the preeminent sci ...
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Time (magazine)
''Time'' (stylized in all caps as ''TIME'') is an American news magazine based in New York City. It was published Weekly newspaper, weekly for nearly a century. Starting in March 2020, it transitioned to every other week. It was first published in New York City on March 3, 1923, and for many years it was run by its influential co-founder, Henry Luce. A European edition (''Time Europe'', formerly known as ''Time Atlantic'') is published in London and also covers the Middle East, Africa, and, since 2003, Latin America. An Asian edition (''Time Asia'') is based in Hong Kong. The South Pacific edition, which covers Australia, New Zealand, and the Pacific Islands, is based in Sydney. Since 2018, ''Time'' has been owned by Salesforce founder Marc Benioff, who acquired it from Meredith Corporation. Benioff currently publishes the magazine through the company Time USA, LLC. History 20th century ''Time'' has been based in New York City since its first issue published on March 3, 1923 ...
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Knight Bachelor
The title of Knight Bachelor is the basic rank granted to a man who has been knighted by the monarch but not inducted as a member of one of the organised Order of chivalry, orders of chivalry; it is a part of the Orders, decorations, and medals of the United Kingdom, British honours system. Knights Bachelor are the most ancient sort of British knight (the rank existed during the 13th-century reign of Henry III of England, King Henry III), but Knights Bachelor rank below knights of chivalric orders. A man who is knighted is formally addressed as "Sir [First Name] [Surname]" or "Sir [First Name]" and his wife as "Lady [Surname]". The designation "Bachelor" in this context conveys the concept of "junior in rank". Criteria Knighthood is usually conferred for public service; amongst its recipients are all male judges of His Majesty's High Court of Justice in England. It is possible to be a Knight Bachelor and a junior member of an order of chivalry without being a knight of that or ...
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Micrococcus Luteus
''Micrococcus luteus'' is a Gram-positive to Gram-variable, nonmotile, tetrad-arranging, pigmented, saprotrophic coccus bacterium in the family Micrococcaceae. It is urease and catalase positive. An obligate aerobe, ''M. luteus'' is found in soil, dust, water and air, and as part of the normal microbiota of the mammalian skin. The bacterium also colonizes the human mouth, mucosae, oropharynx and upper respiratory tract. ''Micrococcus luteus'' is generally harmless but can become an opportunistic pathogen in immunocompromised people or those with indwelling catheters. It resists antibiotic treatment by slowing of major metabolic processes and induction of unique genes. Its genome has a high G + C content. ''Micrococcus luteus'' is coagulase negative, bacitracin susceptible, and forms bright yellow colonies on nutrient agar (hence its scientific species name ''luteus'' which means "yellow" in Latin). ''Micrococcus luteus'' has been shown to survive in oligotrophic environment ...
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Nasal Discharge
Rhinorrhea (American English), also spelled rhinorrhoea or rhinorrhœa (British English), or informally runny nose is the free discharge of a thin mucus fluid from the nose; it is an extremely common condition. It is a common symptom of allergies (hay fever) or certain viral infections, such as the common cold or COVID-19. Rhinorrhea varies in color and consistency depending upon the underlying cause. It can be a side effect of crying, exposure to cold temperatures, cocaine abuse, or drug withdrawal, such as from methadone or other opioids. Treatment for rhinorrhea may be aimed at reducing symptoms or treating underlying causes. Rhinorrhea usually resolves without intervention, but may require treatment by a doctor if symptoms last more than 10 days or if symptoms are the result of foreign bodies in the nose. The term rhinorrhea was coined in 1866 from the Greek ''rhino-'' ("of the nose") and ''-rhoia'' ("discharge" or "flow"). Signs and symptoms Rhinorrhea is characterized by ...
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Enzyme
An enzyme () is a protein that acts as a biological catalyst by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different molecules known as product (chemistry), products. Almost all metabolism, metabolic processes in the cell (biology), cell need enzyme catalysis in order to occur at rates fast enough to sustain life. Metabolic pathways depend upon enzymes to catalyze individual steps. The study of enzymes is called ''enzymology'' and the field of pseudoenzyme, pseudoenzyme analysis recognizes that during evolution, some enzymes have lost the ability to carry out biological catalysis, which is often reflected in their amino acid sequences and unusual 'pseudocatalytic' properties. Enzymes are known to catalyze more than 5,000 biochemical reaction types. Other biocatalysts include Ribozyme, catalytic RNA molecules, also called ribozymes. They are sometimes descr ...
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