Jean Delay (bishop)
Jean Delay (14 November 1907, Bayonne – 29 May 1987, Paris) was a French psychiatrist, neurologist, writer, and a member of the Académie française (Chair 17). His assistant Pierre Deniker conducted a test of chlorpromazine on the male mental ward where Delay worked, and the two published their findings (quickly, with what has been called academic gamesmanship) in 1952. Chlorpromazine turned out to be the first effective drug treatment for mental illness and it had a profound effect on the mentally ill and mental asylums. In 1968–1970, student revolutionaries attacked his offices, and Delay was forced into retirement from medicine. In later life, he lived as a writer. Family and education The son of Maurice Delay, a successful surgeon and mayor of Bayonne, at age fourteen Delay earned a baccalaureate in philosophy. He studied medicine in Paris. After studying in hospitals for twenty years, especially the teaching of Pierre Janet and Georges Dumas, he turned to psychiatry. H ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Bayonne
Bayonne () is a city in southwestern France near the France–Spain border, Spanish border. It is a communes of France, commune and one of two subprefectures in France, subprefectures in the Pyrénées-Atlantiques departments of France, department, in the Nouvelle-Aquitaine regions of France, region. Bayonne is located at the confluence of the Nive and Adour Rivers, in the northern part of the cultural region of the Basque Country (greater region), Basque Country. It is the seat of the Communauté d'agglomération du Pays Basque which roughly encompasses the western half of Pyrénées-Atlantiques, including the coastal city of Biarritz. The area also constitutes the southern part of Gascony, where the Aquitaine Basin joins the beginning of the Pre-Pyrenees. Together with nearby Anglet, Biarritz, Saint-Jean-de-Luz and several smaller communes, Bayonne forms an urban area with 273,137 inhabitants in the 2018 census, 51,411 of whom lived in the commune of Bayonne proper. [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Neurology
Neurology (from , "string, nerve" and the suffix wikt:-logia, -logia, "study of") is the branch of specialty (medicine) , medicine dealing with the diagnosis and treatment of all categories of conditions and disease involving the nervous system, which comprises the Human brain, brain, the spinal cord and the peripheral nervous system , peripheral nerves. Neurological practice relies heavily on the field of neuroscience, the scientific study of the nervous system, using various techniques of neurotherapy. IEEE Brain (2019). "Neurotherapy: Treating Disorders by Retraining the Brain". ''The Future Neural Therapeutics White Paper''. Retrieved 23.01.2025 from: https://brain.ieee.org/topics/neurotherapy-treating-disorders-by-retraining-the-brain/#:~:text=Neurotherapy%20trains%20a%20patient's%20brain,wave%20activity%20through%20positive%20reinforcement International Neuromodulation Society, Retrieved 23 January 2025 from: https://www.neuromodulation.com/ Val Danilov I (2023). "The O ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Schizophrenia
Schizophrenia () is a mental disorder characterized variously by hallucinations (typically, Auditory hallucination#Schizophrenia, hearing voices), delusions, thought disorder, disorganized thinking and behavior, and Reduced affect display, flat or inappropriate affect. Symptoms Prodrome, develop gradually and typically begin during young adulthood and rarely resolve. There is no objective diagnostic test; diagnosis is based on observed behavior, a psychiatric history that includes the person's reported experiences, and reports of others familiar with the person. For a diagnosis of schizophrenia, the described symptoms need to have been present for at least six months (according to the DSM-5) or one month (according to the ICD-11). Many people with schizophrenia have other mental disorders, especially mood disorder, mood, anxiety disorder, anxiety, and substance use disorders, substance use disorders, as well as obsessive–compulsive disorder (OCD). About 0.3% to 0.7% of peo ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Neuroleptic
Antipsychotics, previously known as neuroleptics and major tranquilizers, are a class of psychotropic medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia but also in a range of other psychotic disorders. They are also the mainstay, together with mood stabilizers, in the treatment of bipolar disorder. Moreover, they are also used as adjuncts in the treatment of treatment-resistant major depressive disorder. The use of antipsychotics may result in many unwanted side effects such as involuntary movement disorders, gynecomastia, impotence, weight gain and metabolic syndrome. Long-term use can produce adverse effects such as tardive dyskinesia, tardive dystonia, tardive akathisia, and brain tissue volume reduction. The long term use of antipsychotics often changes the brain both structurally and chemically in a way that can be difficult or impossible to reverse. This can lead to lo ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Isoniazid
Isoniazid, also known as isonicotinic acid hydrazide (INH), is an antibiotic used for the treatment of tuberculosis. For active tuberculosis, it is often used together with rifampicin, pyrazinamide, and either streptomycin or ethambutol. For latent tuberculosis, it is often used alone. It may also be used for atypical types of mycobacteria, such as '' M. avium'', '' M. kansasii'', and '' M. xenopi''. It is usually taken by mouth, but may be used by injection into muscle. History After F. Raschig developed a method to synthesize hydrazine, Hans Meyer and his doctoral student at the German University in Prague Josef Mally studied hydrazides of pyridinecarboxylic acids. By reacting ethyl isonicotinate with hydrazine hydrate they obtained a compound which, after a recrystallization, had a melting point of 163°C. Despite their results published in 1912, its pharmaceutical properties weren't investigated for decades. In the 1940s French physicians discovered that nicotina ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Hierarchy
A hierarchy (from Ancient Greek, Greek: , from , 'president of sacred rites') is an arrangement of items (objects, names, values, categories, etc.) that are represented as being "above", "below", or "at the same level as" one another. Hierarchy is an important concept in a wide variety of fields, such as architecture, philosophy, design, mathematics, computer science, organizational theory, systems theory, systematic biology, and the social sciences (especially political science). A hierarchy can link entities either directly or indirectly, and either vertically or diagonally. The only direct links in a hierarchy, insofar as they are hierarchical, are to one's immediate superior or to one of one's subordinates, although a system that is largely hierarchical can also incorporate alternative hierarchies. Hierarchical links can extend "vertically" upwards or downwards via multiple links in the same direction, following a path (graph theory), path. All parts of the hierarchy that are ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Psilocybin
Psilocybin, also known as 4-phosphoryloxy-''N'',''N''-dimethyltryptamine (4-PO-DMT), is a natural product, naturally occurring tryptamine alkaloid and Investigational New Drug, investigational drug found in more than List of psilocybin mushroom species, 200 species of mushrooms, with Hallucinogen, hallucinogenic and Serotonin, serotonergic effects. Effects include euphoria, changes in perception, a distorted sense of time (via brain desynchronization), and perceived spiritual experiences. It can also cause adverse reactions such as nausea and panic attacks. Its effects depend on set and setting and one's subject-expectancy effect, expectations. Psilocybin is a prodrug of psilocin. That is, the compound itself is biologically inactive but quickly converted by the body to psilocin. Psilocybin is transformed into psilocin by dephosphorylation mediated via phosphatase enzymes. Psilocin is structural analog, chemically related to the neurotransmitter serotonin and acts as a binding ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Mescaline
Mescaline, also known as mescalin or mezcalin, and in chemical terms 3,4,5-trimethoxyphenethylamine, is a natural product, naturally occurring psychedelic drug, psychedelic alkaloid, protoalkaloid of the substituted phenethylamine class, found in Cactus, cacti like peyote (''Lophophora williamsii'') and San Pedro cactus, San Pedro (certain species of the Echinopsis genus) and known for its Serotonin, serotonergic Hallucinogen, hallucinogenic effects. Mescaline is typically taken orally and used recreationally, spiritually, and medically, with psychedelic effects occurring at doses from 100 to 1,000 mg, including microdosing below 75 mg, and it can be consumed in pure form or via mescaline-containing cacti. Mescaline induces a psychedelic experience characterized by vivid visual patterns, altered perception of time and self, synesthesia, and spiritual effects, with an onset of 0.5–0.9 hours and a duration that increases with dose, ranging from about 6 to 14 hours. Mescaline h ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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World Congress Of Psychiatry
The World Psychiatric Association (WPA) is an international umbrella organisation of psychiatric societies. Objectives and goals Originally created to produce world psychiatric congresses, it has evolved to hold regional meetings, to promote professional education and to set ethical, scientific and treatment standards for psychiatry. History Jean Delay was the first president of the Association for the Organization of World Congresses of Psychiatry when it was started in 1950. Donald Ewen Cameron became president of the World Psychiatric Association at its formal founding in 1961. In February 1983, the Soviet All-Union Society of Neurologists and Psychiatrists resigned from the World Psychiatric Association. This resignation occurred as a preemptive action amid a movement to expel the Soviet body from the global organization due to political abuse of psychiatry in the Soviet Union. The Soviet body was conditionally readmitted into the World Psychiatric Association in 1989, f ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Rudolf Hess
Rudolf Walter Richard Hess (Heß in German; 26 April 1894 – 17 August 1987) was a German politician, Nuremberg trials, convicted war criminal and a leading member of the Nazi Party in Nazi Germany, Germany. Appointed Deputy Führer (''Stellvertreter des Führers'') to Adolf Hitler in 1933, Hess held that position until 1941, when he flew solo to Scotland in an attempt to negotiate the United Kingdom's exit from the Second World War. He was taken prisoner and eventually convicted of crimes against peace. He was still serving his life sentence at the time of his suicide in 1987. Hess enlisted as an infantryman in the German Army (German Empire), Imperial German Army at the outbreak of World War I. He was wounded several times during the war and was awarded the Iron Cross, 2nd Class, in 1915. Shortly before the war ended, he enrolled to train as an aviator, but he saw no action in that role. He left the armed forces in December 1918 with the rank of . In 1919, he enrolle ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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World Psychiatric Association
The World Psychiatric Association (WPA) is an international Umbrella organization, umbrella organisation of psychiatric societies. Objectives and goals Originally created to produce world psychiatric congresses, it has evolved to hold regional meetings, to promote professional education and to set ethical, scientific and treatment standards for psychiatry. History Jean Delay was the first president of the Association for the Organization of World Congresses of Psychiatry when it was started in 1950. Donald Ewen Cameron became president of the World Psychiatric Association at its formal founding in 1961. In February 1983, the Soviet All-Union Society of Neurologists and Psychiatrists resigned from the World Psychiatric Association. This resignation occurred as a preemptive action amid a movement to expel the Soviet body from the global organization due to political abuse of psychiatry in the Soviet Union. The Soviet body was conditionally readmitted into the World Psychiatric ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Entrée Hôpital Sainte-Anne, Rue Cabanis
An entrée (, ; ), in modern French table service and that of much of the English-speaking world, is a dish served before the main course of a meal. Outside North America and parts of English-speaking Canada, it is generally synonymous with the terms ''hors d'oeuvre'', ''appetizer'', or ''starter''. It may be the first dish served, or it may follow a soup or other small dish or dishes. In the United States and parts of English-speaking Canada, the term ''entrée'' instead refers to the main course or the only course of a meal. Early use of the term The word ''entrée'' as a culinary term first appears in print around 1536 in the ''Petit traicté auquel verrez la maniere de faire cuisine'', more widely known from a later edition titled ''Livre fort excellent de cuisine'', in a collection of menus at the end of the book. There, the first stage of each meal is called the ''entree de table'' (entrance to the table); the second stage consists of '' potaiges'' (foods boiled or simme ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |