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Ibrahim Cissé (academic)
Ibrahim I. Cissé is a Nigerien-American biophysicist. He is currently director of the Max Planck Institute of Immunobiology and Epigenetics. Previously, Cissé was at the California Institute of Technology as Professor of Physics and the Massachusetts Institute of Technology as Professor of Physics and Biology. He has won several awards for his work, including in 2021 the MacArthur Fellowship. Cissé's research focuses on live cell super-resolution imaging and single molecule characterisation. Early life and education Cissé was born in Niamey, Niger. As a child he assumed that he would work in his father's law firm. He became interested in science through Hollywood (film industry), Hollywood films. In Niamey there were few opportunities to practise science as his school did not have a laboratory. He was keen to move to America to study, and completed high school two years early. He moved to the United States at the age of 17 to attend college. Cissé studied physics at the N ...
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Max Planck Institute Of Immunobiology And Epigenetics
The Max Planck Institute of Immunobiology and Epigenetics (German language, German: ''Max-Planck-Institut für Immunbiologie und Epigenetik'') in Freiburg im Breisgau, Freiburg, Germany is an interdisciplinary research institute that conducts basic research in modern immunobiology, developmental biology and epigenetics. It was founded in 1961 as the Max Planck Institute of Immunobiology and is one of 86 institutions of the Max Planck Society. Originally named the Max Planck Institute of Immunobiology, it was renamed to its current name in 2010 as it widened its research thrusts to the study of epigenetics. The researchers of the institute study the development of the immune system and analyse the genes and molecules which are important for its function. They also seek to establish which factors control the maturation of immune cells and how chemical changes of the DNA influence the immune defense. The biologist Georges J. F. Köhler, a co-recipient of the 1984 Nobel Prize in Physi ...
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Caltech
The California Institute of Technology (branded as Caltech) is a private university, private research university in Pasadena, California, United States. The university is responsible for many modern scientific advancements and is among a small group of Institute of Technology (United States), institutes of technology in the United States that are devoted to the instruction of pure and applied sciences. The institution was founded as a preparatory and vocational school by Amos G. Throop in 1891 and began attracting influential scientists such as George Ellery Hale, Arthur Amos Noyes, and Robert Andrews Millikan in the early 20th century. The vocational and preparatory schools were disbanded and spun off in 1910, and the college assumed its present name in 1920. In 1934, Caltech was elected to the Association of American Universities, and the antecedents of NASA's Jet Propulsion Laboratory, which Caltech continues to manage and operate, were established between 1936 and 1943 under ...
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Princeton University
Princeton University is a private university, private Ivy League research university in Princeton, New Jersey, United States. Founded in 1746 in Elizabeth, New Jersey, Elizabeth as the College of New Jersey, Princeton is the List of Colonial Colleges, fourth-oldest institution of higher education in the United States and one of the nine colonial colleges chartered before the American Revolution. The institution moved to Newark, New Jersey, Newark in 1747 and then to its Mercer County, New Jersey, Mercer County campus in Princeton nine years later. It officially became a university in 1896 and was subsequently renamed Princeton University. The university is governed by the Trustees of Princeton University and has an endowment of $37.7 billion, the largest List of colleges and universities in the United States by endowment, endowment per student in the United States. Princeton provides undergraduate education, undergraduate and graduate education, graduate instruction in the hu ...
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RNA Polymerase II
RNA polymerase II (RNAP II and Pol II) is a Protein complex, multiprotein complex that Transcription (biology), transcribes DNA into precursors of messenger RNA (mRNA) and most small nuclear RNA (snRNA) and microRNA. It is one of the three RNA polymerase, RNAP enzymes found in the nucleus of eukaryote, eukaryotic cells. A 550 kDa complex of 12 subunits, RNAP II is the most studied type of RNA polymerase. A wide range of transcription factors are required for it to bind to upstream gene promoter (biology), promoters and begin transcription. Discovery Early studies suggested a minimum of two RNAPs: one which synthesized rRNA in the nucleolus, and one which synthesized other RNA in the nucleoplasm, part of the nucleus but outside the nucleolus. In 1969, biochemists Robert G. Roeder and William J. Rutter, William Rutter discovered there are total three distinct nuclear RNA polymerases, an additional RNAP that was responsible for transcription of some kind of RNA in the nucleoplasm. ...
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Photoactivated Localization Microscopy
Photo-activated localization microscopy (PALM or FPALM) and stochastic optical reconstruction microscopy (STORM) are widefield (as opposed to point scanning techniques such as laser scanning confocal microscopy) fluorescence microscopy imaging methods that allow obtaining images with a resolution beyond the diffraction limit. The methods were proposed in 2006 in the wake of a general emergence of optical super-resolution microscopy methods, and were featured as Methods of the Year for 2008 by the ''Nature Methods'' journal. The development of PALM as a targeted biophysical imaging method was largely prompted by the discovery of new species and the engineering of mutants of fluorescent proteins displaying a controllable photochromism, such as photo-activatible Green fluorescent protein, GFP. However, the concomitant development of STORM, sharing the same fundamental principle, originally made use of paired cyanine dyes. One molecule of the pair (called activator), when excited near ...
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In Vitro
''In vitro'' (meaning ''in glass'', or ''in the glass'') Research, studies are performed with Cell (biology), cells or biological molecules outside their normal biological context. Colloquially called "test-tube experiments", these studies in biology and its subdisciplines are traditionally done in labware such as test tubes, flasks, Petri dishes, and microtiter plates. Studies conducted using components of an organism that have been isolated from their usual biological surroundings permit a more detailed or more convenient analysis than can be done with whole organisms; however, results obtained from ''in vitro'' experiments may not fully or accurately predict the effects on a whole organism. In contrast to ''in vitro'' experiments, ''in vivo'' studies are those conducted in living organisms, including humans, known as clinical trials, and whole plants. Definition ''In vitro'' (Latin language, Latin for "in glass"; often not italicized in English usage) studies are conducted ...
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Photoactivated Localization Microscopy
Photo-activated localization microscopy (PALM or FPALM) and stochastic optical reconstruction microscopy (STORM) are widefield (as opposed to point scanning techniques such as laser scanning confocal microscopy) fluorescence microscopy imaging methods that allow obtaining images with a resolution beyond the diffraction limit. The methods were proposed in 2006 in the wake of a general emergence of optical super-resolution microscopy methods, and were featured as Methods of the Year for 2008 by the ''Nature Methods'' journal. The development of PALM as a targeted biophysical imaging method was largely prompted by the discovery of new species and the engineering of mutants of fluorescent proteins displaying a controllable photochromism, such as photo-activatible Green fluorescent protein, GFP. However, the concomitant development of STORM, sharing the same fundamental principle, originally made use of paired cyanine dyes. One molecule of the pair (called activator), when excited near ...
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European Molecular Biology Organization
The European Molecular Biology Organization (EMBO) is a professional, non-profit organization of more than 2,100 life scientists. Its goal is to promote research in life science and enable international exchange between scientists. It co-funds courses, workshops and conferences, publishes five scientific journals and supports individual scientists. The organization was founded in 1964 and is a founding member of the Initiative for Science in Europe. the Director of EMBO is Fiona Watt, a stem cell researcher, professor at King's College London and a group leader at the European Molecular Biology Laboratory. __TOC__ Conferences and journals In recent years, EMBO has funded more than 80 meetings with more than 12,000 participants each year. EMBO publishes five peer-reviewed scientific journals: ''The EMBO Journal'', ''EMBO Reports'', '' Molecular Systems Biology'', '' EMBO Molecular Medicine'', and '' Life Science Alliance''. History The European Molecular Biology Organizatio ...
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Xavier Darzacq
Xavier or Xabier may refer to: Place * Xavier, Spain People * Xavier (surname) * Xavier (given name) * Francis Xavier (1506–1552), Catholic saint ** St. Francis Xavier (other) * St. Xavier (other) * Xavier (footballer, born January 1980) (Anderson Conceição Xavier), Brazilian midfielder * Xavier (footballer, born March 1980) (José Xavier Costa), Brazilian left-back * Xavier (footballer, born 2000) (João Vitor Xavier de Almeida), Brazilian midfielder * Xavier (wrestler), American professional wrestler Arts and entertainment * '' Xavier: Renegade Angel'', an animated TV series * Xavier Institute, a fictional school in Marvel comics * Charles Xavier, Professor X, a fictional Marvel Comics character * "Xavier", a song by Casseurs Flowters from the 2015 soundtrack album ''Comment c'est loin'' * "Xavier", a song by Dead Can Dance from the 1987 album ''Within the Realm of a Dying Sun'' Other uses * Xavier University, in Cincinnati, U.S. * Xavier University of L ...
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Maxime Dahan
Maxime is a French given name that may refer to: People *Maxime Bernier (born 1963), former Canadian Minister of Foreign Affairs *Maxime Bôcher (1867–1918), an American mathematician * Maxime Boyer (born 1984), a Canadian professional wrestler *Maxime Du Camp (1822–1894), a French writer and photographer * Maxime Chaya (born 1961), a Lebanese explorer *Maxime Cressy (born 1997), an American tennis player *Maxime Dupé (born 1993), a French footballer *Maxime Faget (1921–2004), an American mechanical engineer and *Maxime Guyon (born 1989), a French flat racing jockey * Maxime Hordies (born 1996), Belgian para-cyclist * Maxime Laisney (born 1981), a French politician *Maxime Le Forestier (born 1949), a French singer * Maxime Médard (born 1986), a French Rugby Union player * Maxime Minot (born 1987), a French politician * Maxime Monfort (born 1983), a Belgian racing cyclist * Maxime Partouche (born 1990), a French footballer *Maxime Rodinson (1915–2004), a French historia ...
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Taekjip Ha
Taekjip Ha (born February 20, 1968) is a South Korean-born American biophysicist who is currently a Senior investigator and director of Program in Cellular and Molecular Medicine at Boston Children's Hospital and Professor of Pediatrics, Harvard Medical School. He was previously Bloomberg Distinguished Professor of Biophysics and Biomedical Engineering at Johns Hopkins University. He was previously the Gutgsell Professor of Physics, at University of Illinois at Urbana-Champaign where he was the principal investigator of Single Molecule Nanometry group. He is also a Howard Hughes Medical Institute investigator. Biography Ha was born in Seoul, South Korea on February 20, 1968. He received a B.S. degree in physics at Seoul National University in 1990, and joined the physics department at University of California, Berkeley where he began to study atomic physics in the lab of Raymond Jeanloz in Berkeley's geophysics department. He worked on a project to place nitrogen and carbon unde ...
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Science (journal)
''Science'' is the peer review, peer-reviewed academic journal of the American Association for the Advancement of Science (AAAS) and one of the world's top academic journals. It was first published in 1880, is currently circulated weekly and has a subscriber base of around 130,000. Because institutional subscriptions and online access serve a larger audience, its estimated readership is over 400,000 people. ''Science'' is based in Washington, D.C., United States, with a second office in Cambridge, UK. Contents The major focus of the journal is publishing important original scientific research and research reviews, but ''Science'' also publishes science-related news, opinions on science policy and other matters of interest to scientists and others who are concerned with the wide implications of science and technology. Unlike most scientific journals, which focus on a specific field, ''Science'' and its rival ''Nature (journal), Nature'' cover the full range of List of academ ...
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