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Human Proteome Organization
The Human Proteome Organization (HUPO) is an international consortium of national proteomics research associations, government researchers, academic institutions, and industry partners. The organization was launched in February 2001, and it promotes the development and awareness of proteomics research, advocates on behalf of proteomics researchers throughout the world, and facilitates scientific collaborations between members and initiatives. Ultimately, it is organized to gain a better and more complete understanding of the human proteome. Congress Since 2002, HUPO organizes one international congress each year, with past congresses held in Cancun in 2022, virtually in 2021 and 2020, Adelaide in 2019, Orlando in 2018, in Dublin in 2017, in Taipei in 2016 and in Vancouver 2015. Awards HUPO awards multiple awards each year, among them the * Distinguished Service Award * Translational Proteomics Award * Science & Technology Award * Discovery in Proteomic Sciences Award * Disting ...
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Proteomics
Proteomics is the large-scale study of proteins. Proteins are vital macromolecules of all living organisms, with many functions such as the formation of structural fibers of muscle tissue, enzymatic digestion of food, or synthesis and replication of DNA. In addition, other kinds of proteins include antibodies that protect an organism from infection, and hormones that send important signals throughout the body. The proteome is the entire set of proteins produced or modified by an organism or system. Proteomics enables the identification of ever-increasing numbers of proteins. This varies with time and distinct requirements, or stresses, that a cell or organism undergoes. Proteomics is an interdisciplinary domain that has benefited greatly from the genetic information of various genome projects, including the Human Genome Project. It covers the exploration of proteomes from the overall level of protein composition, structure, and activity, and is an important component of function ...
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Proteome
A proteome is the entire set of proteins that is, or can be, expressed by a genome, cell, tissue, or organism at a certain time. It is the set of expressed proteins in a given type of cell or organism, at a given time, under defined conditions. Proteomics is the study of the proteome. Types of proteomes While proteome generally refers to the proteome of an organism, multicellular organisms may have very different proteomes in different cells, hence it is important to distinguish proteomes in cells and organisms. A cellular proteome is the collection of proteins found in a particular cell (biology), cell type under a particular set of environmental conditions such as exposure to hormone, hormone stimulation. It can also be useful to consider an organism's complete proteome, which can be conceptualized as the complete set of proteins from all of the various cellular proteomes. This is very roughly the protein equivalent of the genome. The term ''proteome'' has also been used to r ...
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Adelaide
Adelaide ( , ; ) is the list of Australian capital cities, capital and most populous city of South Australia, as well as the list of cities in Australia by population, fifth-most populous city in Australia. The name "Adelaide" may refer to either Greater Adelaide (including the Adelaide Hills) or the Adelaide city centre; the demonym ''Adelaidean'' is used to denote the city and the residents of Adelaide. The Native title in Australia#Traditional owner, traditional owners of the Adelaide region are the Kaurna, with the name referring to the area of the city centre and surrounding Adelaide Park Lands, Park Lands, in the Kaurna language. Adelaide is situated on the Adelaide Plains north of the Fleurieu Peninsula, between the Gulf St Vincent in the west and the Mount Lofty Ranges in the east. Its metropolitan area extends from the coast to the Adelaide Hills, foothills of the Mount Lofty Ranges, and stretches from Gawler in the north to Sellicks Beach in the south. Named in ho ...
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Orlando, Florida
Orlando ( ) is a city in and the county seat of Orange County, Florida, United States. The city proper had a population of 307,573 at the 2020 census, making it the fourth-most populous city in Florida behind Jacksonville, Florida, Jacksonville, Miami, and Tampa, Florida, Tampa and the state's most populous inland city. Part of Central Florida, it is the center of the Greater Orlando, Orlando metropolitan area, which had a population of 2.67 million in 2020. It is the sixth-largest metropolitan area in the Southern United States and the third-largest metropolitan area in Florida behind Miami metropolitan area, Miami and Tampa Bay area, Tampa Bay. Orlando is one of the most-visited cities in the world primarily due to tourism, major events, and convention traffic. It is the fourth-most visited city in the U.S. after New York City, Miami, and Los Angeles, with over 3.5 million visitors as of 2023. Orlando International Airport is the List of the busiest airports in the United Stat ...
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Dublin
Dublin is the capital and largest city of Republic of Ireland, Ireland. Situated on Dublin Bay at the mouth of the River Liffey, it is in the Provinces of Ireland, province of Leinster, and is bordered on the south by the Dublin Mountains, part of the Wicklow Mountains range. Dublin is the largest city by population on the island of Ireland; at the 2022 census of Ireland, 2022 census, the city council area had a population of 592,713, while the city including suburbs had a population of 1,263,219, County Dublin had a population of 1,501,500. Various definitions of a metropolitan Greater Dublin Area exist. A settlement was established in the area by the Gaels during or before the 7th century, followed by the Vikings. As the Kingdom of Dublin grew, it became Ireland's principal settlement by the 12th century Anglo-Norman invasion of Ireland. The city expanded rapidly from the 17th century and was briefly the second largest in the British Empire and sixth largest in Western Europ ...
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Taipei
, nickname = The City of Azaleas , image_map = , map_caption = , pushpin_map = Taiwan#Asia#Pacific Ocean#Earth , coordinates = , subdivision_type = Country , subdivision_name = Taiwan , established_title = Settled , established_date = 1709 , established_title1 = Renamed Taihoku , established_date1 = 17 April 1895 , established_title2 = Provincial city (Taiwan), Provincial city status , established_date2 = 25 October 1945 , established_title3 = Retreat of the government of the Republic of China to Taiwan, Provisional national capital , established_date3 = 7 December 1949 , established_title4 = Reconstituted as a Yuan-controlled municipality , established_date4 = 1 July 1967 , capital_type = City seat , capital = Xinyi District, Taipei, Xinyi District , largest_settlement ...
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Vancouver
Vancouver is a major city in Western Canada, located in the Lower Mainland region of British Columbia. As the List of cities in British Columbia, most populous city in the province, the 2021 Canadian census recorded 662,248 people in the city, up from 631,486 in 2016. The Metro Vancouver area had a population of 2.6million in 2021, making it the List of census metropolitan areas and agglomerations in Canada#List, third-largest metropolitan area in Canada. Greater Vancouver, along with the Fraser Valley, comprises the Lower Mainland with a regional population of over 3million. Vancouver has the highest population density in Canada, with over , and the fourth highest in North America (after New York City, San Francisco, and Mexico City). Vancouver is one of the most Ethnic origins of people in Canada, ethnically and Languages of Canada, linguistically diverse cities in Canada: 49.3 percent of its residents are not native English speakers, 47.8 percent are native speakers of nei ...
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Human Genome Organisation
The Human Genome Organisation (HUGO) is a non-profit organization founded in 1988. HUGO represents an international coordinating scientific body in response to initiatives such as the Human Genome Project. HUGO has four active committees, including the HUGO Gene Nomenclature Committee (HGNC), and the HUGO Committee on Ethics, Law and Society (CELS). History HUGO was established at the first meeting on genome mapping and sequencing at Cold Spring Harbor in 1988. The idea of starting the organization stemmed from South African biologist Sydney Brenner, who is best known for his significant contributions to work on the genetic code and other areas of molecular biology, as well as winning the 2002 Nobel Prize in Physiology or Medicine. A Founding Council was elected at the meeting with a total of 42 scientists from 17 different countries, with Victor A. McKusick serving as founding President. In 2016, HUGO was located at the EWHA Womans University in Seoul, South Korea. In 2020, the ...
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Human Genome Project
The Human Genome Project (HGP) was an international scientific research project with the goal of determining the base pairs that make up human DNA, and of identifying, mapping and sequencing all of the genes of the human genome from both a physical and a functional standpoint. It started in 1990 and was completed in 2003. It was the world's largest collaborative biological project. Planning for the project began in 1984 by the US government, and it officially launched in 1990. It was declared complete on 14 April 2003, and included about 92% of the genome. Level "complete genome" was achieved in May 2021, with only 0.3% of the bases covered by potential issues. The final gapless assembly was finished in January 2022. Funding came from the US government through the National Institutes of Health (NIH) as well as numerous other groups from around the world. A parallel project was conducted outside the government by the Celera Corporation, or Celera Genomics, which was formall ...
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Proteomics Standards Initiative
The Proteomics Standards Initiative (PSI) is a working group of the Human Proteome Organization. It aims to define data standards for proteomics to facilitate data comparison, exchange and verification. The Proteomics Standards Initiative focuses on the following subjects: minimum information about a proteomics experiment defines the metadata that should be provided along with a proteomics experiment. a data markup language for encoding the data, and metadata ontologies for consistent annotation and representation. Minimum information about a proteomics experiment Minimum information about a proteomics experiment (MIAPE) is a minimum information standard, created by the Proteomics Standards Initiative of the Human Proteome Organization, for reporting proteomics experiments. You can't just introduce the results of an analysis, it is intended to specify all the information necessary to interpret the experiment results unambiguously and to potentially reproduce the experiment. Wh ...
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Human Proteome Project
The Human Proteome Project (HPP) is a collaborative effort coordinated by the Human Proteome Organization. Its stated goal is to experimentally observe all of the proteins produced by the sequences translated from the human genome. History The Human Proteome Organization has served as a coordinating body for many long-running proteomics research projects associated with specific human tissues of clinical interest, such as blood plasma, liver, brain and urine. It has also been responsible for projects associated with specific technology and standards necessary for the large scale study of proteins. The structure and goals of a larger project that would parallel the Human Genome Project The Human Genome Project (HGP) was an international scientific research project with the goal of determining the base pairs that make up human DNA, and of identifying, mapping and sequencing all of the genes of the human genome from both a ... has been debated in the scientific literature ...
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