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Howard Y. Chang
Howard Yuan-Hao Chang (traditional Chinese: 張元豪; born 1972) is a Taiwanese-American physician-scientist and is the senior vice president of research and chief scientific officer of Amgen. He was previously the Virginia and D. K. Ludwig Professor of Cancer Genomics and of Genetics at the Stanford University School of Medicine. He is best known for his research with long non-coding RNAs. a principal investigator at the Howard Hughes Medical Institute, Biography Chang was born in Taipei, Taiwan, to a Taiwanese family of physicians. His father, Chang Chau-hsiung, was a Taiwanese physician and politician. Chang earned a bachelor's degree in biochemistry from Harvard University and completed a Ph.D. in biology at the Massachusetts Institute of Technology (MIT) and earned a Doctor of Medicine (M.D.) at Harvard Medical School as part of the "Harvard-MIT physician scientist training program" working in David Baltimore's laboratory. He did his dermatology residency and postdoct ...
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Molecular Biology
Molecular biology is a branch of biology that seeks to understand the molecule, molecular basis of biological activity in and between Cell (biology), cells, including biomolecule, biomolecular synthesis, modification, mechanisms, and interactions. Though cells and other microscopic structures had been observed in living organisms as early as the 18th century, a detailed understanding of the mechanisms and interactions governing their behavior did not emerge until the 20th century, when technologies used in physics and chemistry had advanced sufficiently to permit their application in the biological sciences. The term 'molecular biology' was first used in 1945 by the English physicist William Astbury, who described it as an approach focused on discerning the underpinnings of biological phenomena—i.e. uncovering the physical and chemical structures and properties of biological molecules, as well as their interactions with other molecules and how these interactions explain observ ...
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HOTAIR
HOTAIR (for HOX transcript antisense RNA) is a human gene located between HOXC11 and HOXC12 on chromosome 12. It is the first example of an RNA expressed on one chromosome that has been found to influence the transcription of the HOXD cluster posterior genes located on chromosome 2. The sequence and function of HOTAIR are different in humans and mice. Sequence analysis of HOTAIR revealed that it exists in mammals, has poorly conserved sequences and considerably conserved structures, and has evolved faster than nearby HoxC genes. A subsequent study identified HOTAIR has 32 nucleotides long conserved noncoding element ( CNE) that has a paralogous copy in HOXD cluster region (located between HOXD11 and HOXD12), suggesting that the HOTAIR conserved sequences predate whole genome duplication events at the root of vertebrate. While the conserved sequence paralogous with HOXD cluster is 32 nucleotide long, the HOTAIR sequence conserved from human to fish is about 200 nucleotide long ...
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1972 Births
Within the context of Coordinated Universal Time (UTC) it was the longest year ever, as two leap seconds were added during this 366-day year, an event which has not since been repeated. (If its start and end are defined using Solar time, mean solar time [the legal time scale], its duration was 31622401.141 seconds of Terrestrial Time (or Ephemeris Time), which is slightly shorter than 1908 in science#Astronomy, 1908). Events January * January 1 – Kurt Waldheim becomes Secretary-General of the United Nations. * January 4 – The first scientific hand-held calculator (HP-35) is introduced (price $395). * January 7 – Iberia Airlines Flight 602 crashes into a 462-meter peak on the island of Ibiza; 104 are killed. * January 9 – The RMS Queen Elizabeth, RMS ''Queen Elizabeth'' catches fire and sinks in Hong Kong's Victoria harbor while undergoing conversion to a floating university. * January 10 – Independence leader Sheikh Mujibur Rahman returns to Bangladesh after s ...
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Lynne E
Lynne may refer to: *Lynne (surname) *Lynne (given name) *Lynne, Florida Lynne is an Unincorporated area#United States, unincorporated community in Marion County, Florida, Marion County, in the U.S. state of Florida. It is located along Florida State Road 40 in the western edges of Ocala National Forest. History A po ..., an unincorporated community * Lynne, Wisconsin, a town in Oneida County, Wisconsin, United States {{Disambig ...
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Adrian Krainer (scientist)
Adrian Robert Krainer is a Uruguayan-American biochemist and molecular geneticist known for his research into RNA gene-splicing. He helped create a drug for patients with spinal muscular atrophy. Krainer holds the St. Giles Foundation Professorship at Cold Spring Harbor Laboratory in Laurel Hollow, New York. Early life and education Krainer was born in Montevideo, Uruguay to a Jewish family of Hungarian and Romanian descent. He has one older brother, who is a chemical engineer. His father did forced labor for two years in a Romanian labor camp (Ferma Alba) during World War II. After the war, his father's original surname, Kreiner changed to Krainer due to a clerical error when he was a refugee in Italy. His parents owned a small leather business in Montevideo. Krainer attended a private bilingual French-Spanish elementary school. He later attended a public school for two years before completing his pre-college education with four years at a private Spanish-Hebrew school. Kr ...
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Albany Medical Center Prize
The Albany Medical Center Prize in Medicine and Biomedical Research is the United States' second highest value prize in medicine and biomedical research, awarded by the Albany Medical Center. Among prizes for medicine worldwide, the Albany Medical Center Prize is the fourth most lucrative (after the $3 million Breakthrough Prize in Life Sciences, the $1.2 million Nobel Prize in Medicine and the $1 million Shaw Prize in life science and medicine). Awarded annually, the $500,000 prize is bestowed to any physician or scientist, or group, whose work has led to significant advances in the fields of health care and scientific research with demonstrated translational benefits applied to improved patient care. The prize is a legacy to its founder, the late Morris "Marty" Silverman. At the inaugural awards ceremony in Albany, NY in March 2001, Silverman started a tradition that will be carried on for one hundred years, the duration of the Prize. Silverman's promise was to light one can ...
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American Society For Clinical Investigation
The American Society for Clinical Investigation (ASCI), established in 1908, is one of the oldest and most respected medical honor societies in the United States. Organization and purpose The ASCI is an honorary society to which more than 2,800 physician-scientists from all medical specialties belong. Prospective members are proposed by standing members of the society and elected to ASCI on the basis of an outstanding record of scholarly achievement in biomedical research. The ASCI includes physician-scientists who are active clinically, in basic research, or in teaching. Many of its senior members are widely recognized leaders in academic medicine. As of 2015 the membership of ASCI has included 417 members of the National Academy of Medicine, 191 members of the National Academies of Sciences, Engineering, and Medicine The National Academies of Sciences, Engineering, and Medicine (NASEM), also known as the National Academies, is a Congressional charter, congressionally charte ...
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King Faisal Prize
The King Faisal Prize (, formerly King Faisal International Prize), is an annual award sponsored by King Faisal Foundation presented to "dedicated men and women whose contributions make a positive difference". The foundation awards prizes in five categories: Service to Islam; Islamic studies; the Arabic language and Arabic literature; science; and medicine. The first King Faisal Prize was awarded to the Pakistani scholar Abul A'la Maududi Abul A'la al-Maududi (; – ) was an Islamic scholar, Islamist ideologue, Muslim philosopher, jurist, historian, journalist, activist, and scholar active in British India and later, following the partition, in Pakistan. Described by Wilfred C ... in 1979 for his service to Islam. In 1981, Khalid of Saudi Arabia received the same award. In 1984, Fahd of Saudi Arabia was the recipient of the award. In 1986, this prize was co-awarded to Ahmed Deedat and French Roger Garaudy. Award process Designation of subjects Each year, the selection ...
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Lurie Prize In Biomedical Sciences
The Lurie Prize in Biomedical Sciences recognizes outstanding achievement by a promising young scientist in biomedical research. It is awarded annually by the Foundation for the National Institutes of Health. Established in 2013 the award is worth $100,000 and was made possible by the gift of FNIH board member Ann Lurie. Prizewinners are selected by a jury of six distinguished biomedical researchers from a list of nominations. Recipients SourceFNIH*2024: Howard Y. Chang * 2023: Navdeep S. Chandel, Vamsi Mootha * 2022: Anne Brunet, Andrew Dillin * 2021: Xiaowei Zhuang * 2020: Aviv Regev * 2019: Yasmine Belkaid * 2018: Zhijian “James” Chen * 2017: David M. Sabatini * 2016: Jeannie T. Lee * 2015: Karl Deisseroth * 2014: Jennifer Doudna Jennifer Anne Doudna (; born February 19, 1964) is an American biochemist who has pioneered work in CRISPR gene editing, and made other fundamental contributions in biochemistry and genetics. She received the 2020 Nobel Prize in Chem ...
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National Academy Of Sciences
The National Academy of Sciences (NAS) is a United States nonprofit, NGO, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the National Academy of Medicine (NAM). As a national academy, new members of the organization are elected annually by current members, based on their distinguished and continuing achievements in original research. Election to the National Academy is one of the highest honors in the scientific field in the United States. Member of the National Academy of Sciences, Members of the National Academy of Sciences serve ''pro bono'' as "advisers to the nation" on science, engineering, and medicine. The group holds a congressional charter under Title 36 of the United States Code. Congress legislated and President Abraham Lincoln signed an Act of Congress (1863) establishing the National Academy of Sciences as an independent, trusted nongovernmen ...
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American Academy Of Arts And Sciences
The American Academy of Arts and Sciences (The Academy) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, and other Founding Fathers of the United States. It is headquartered in Cambridge, Massachusetts. Membership in the academy is achieved through a nominating petition, review, and election process. The academy's quarterly journal, '' Dædalus'', is published by the MIT Press on behalf of the academy, and has been open-access since January 2021. The academy also conducts multidisciplinary public policy research. Laurie L. Patton has served as President of the Academy since January 2025. History The Academy was established by the Massachusetts legislature on May 4, 1780, charted in order "to cultivate every art and science which may tend to advance the interest, honor, dignity, and happiness of a free, independent, and virtuous people." The sixty-tw ...
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NAS Award In Molecular Biology
The NAS Award in Molecular Biology is awarded by the U.S. National Academy of Sciences "for recent notable discovery in molecular biology by a young scientist who is a citizen of the United States." It has been awarded annually since its inception in 1962. List of NAS Award in Molecular Biology winners SourceNAS * 1962 Marshall Nirenberg for his studies of the molecular mechanisms for the biosynthesis of protein. * 1963 Matthew Meselson for his leading role in developing and applying methods to measure the transmission of genetic information in the cell. * 1964 Charles Yanofsky for his achievements in demonstrating how changes in the gene produce changes in the way protein is made in the body. * 1965 Robert Stuart Edgar for his development and application of the method of "conditional lethal mutants" for the analysis of the genetic control of morpho-genesis at the molecular level. * 1966 Norton D. Zinder for his discovery of RNA bacteriophages, a new class of bacteria-attackin ...
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