Howard Rasmussen
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Howard Rasmussen
Howard Rasmussen (1925–2005) was an American physician-scientist known for his research on aldosterone and insulin secretion. Early life and education Howard Rasmussen was born March 1, 1925, in Harrisburg, Pennsylvania, to Frederick Rasmussen and Faith Elliott. He grew up on a Pennsylvania dairy farm with five brothers. As a young man, he served in the United States military in World War II in Europe, earning a Purple Heart with an oak leaf cluster. At the war's conclusion, Rasmussen attended Gettysburg College, earning a Bachelor of Science in 1948. He then went on to medical school at Harvard University, earning his medical degree in 1952, followed by training in internal medicine at Massachusetts General Hospital. Rasmussen then spent 1955–1956 as a research fellow at University College London, before returning to the US to pursue a PhD – which he was awarded by Rockefeller University in 1959. Academic career Following his PhD, Rasmussen stayed for a short time at R ...
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Aldosterone
Aldosterone is the main mineralocorticoid steroid hormone produced by the zona glomerulosa of the adrenal cortex in the adrenal gland. It is essential for sodium conservation in the kidney, salivary glands, sweat glands, and colon. It plays a central role in the homeostatic regulation of blood pressure, plasma sodium (Na+), and potassium (K+) levels. It does so primarily by acting on the mineralocorticoid receptors in the distal tubules and collecting ducts of the nephron. It influences the reabsorption of sodium and excretion of potassium (from and into the tubular fluids, respectively) of the kidney, thereby indirectly influencing water retention or loss, blood pressure, and blood volume.Marieb Human Anatomy & Physiology 9th edition, chapter:16, page:629, question number:14 When dysregulated, aldosterone is pathogenic and contributes to the development and progression of cardiovascular and kidney disease. Aldosterone has exactly the opposite function of the atrial nat ...
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Yale University
Yale University is a Private university, private Ivy League research university in New Haven, Connecticut, United States. Founded in 1701, Yale is the List of Colonial Colleges, third-oldest institution of higher education in the United States, and one of the nine colonial colleges chartered before the American Revolution. Yale was established as the Collegiate School in 1701 by Congregationalism in the United States, Congregationalist clergy of the Connecticut Colony. Originally restricted to instructing ministers in theology and sacred languages, the school's curriculum expanded, incorporating humanities and sciences by the time of the American Revolution. In the 19th century, the college expanded into graduate and professional instruction, awarding the first Doctor of Philosophy, PhD in the United States in 1861 and organizing as a university in 1887. Yale's faculty and student populations grew rapidly after 1890 due to the expansion of the physical campus and its scientif ...
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University Of Wisconsin–Madison Faculty
A university () is an institution of tertiary education and research which awards academic degrees in several academic disciplines. ''University'' is derived from the Latin phrase , which roughly means "community of teachers and scholars". Universities typically offer both undergraduate and postgraduate programs. The first universities in Europe were established by Catholic monks. The University of Bologna (), Italy, which was founded in 1088, is the first university in the sense of: *being a high degree-awarding institute. *using the word (which was coined at its foundation). *having independence from the ecclesiastic schools and issuing secular as well as non-secular degrees (with teaching conducted by both clergy and non-clergy): grammar, rhetoric, logic, theology, canon law and notarial law.Hunt Janin: "The university in medieval life, 1179–1499", McFarland, 2008, , p. 55f.de Ridder-Symoens, Hilde''A History of the University in Europe: Volume 1, Universities in the Mid ...
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Rockefeller University Alumni
Rockefeller is a German surname, originally given to people from the now-abandoned village of Rockenfeld near Neuwied in the Rhineland and commonly referring to subjects associated with the Rockefeller family. It may refer to: People with the name Rockefeller family *John D. Rockefeller Sr. (1839–1937), founder of the Standard Oil Company * Laura Spelman Rockefeller (1839–1915), wife of John D.R., namesake of Spelman College * William Rockefeller (1841–1922), brother of John D.R. * Bessie Rockefeller Strong (1866–1906), daughter of John D.R. * Alta Rockefeller Prentice (1871–1962), daughter of John D.R., founder Alta House (settlement house) *Edith Rockefeller McCormick (1872–1932), daughter of John D.R., feminist, philanthropist * John D. Rockefeller Jr. (Junior) (1874–1960), son of Senior *Abby Aldrich Rockefeller (1874–1948), wife of Junior * Percy Avery Rockefeller (1878–1934), son of William * Margaret Rockefeller Strong de Larraín, Marquesa de Cuevas (1897†...
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Harvard Medical School Alumni
Harvard University is a private Ivy League research university in Cambridge, Massachusetts, United States. Founded in 1636 and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher learning in the United States. Its influence, wealth, and rankings have made it one of the most prestigious universities in the world. Harvard was founded and authorized by the Massachusetts General Court, the governing legislature of colonial-era Massachusetts Bay Colony. While never formally affiliated with any denomination, Harvard trained Congregational clergy until its curriculum and student body were gradually secularized in the 18th century. By the 19th century, Harvard emerged as the most prominent academic and cultural institution among the Boston elite. Following the American Civil War, under Harvard president Charles William Eliot's long tenure from 1869 to 1909, Harvard developed multiple professional schools, which transforme ...
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Gettysburg College Alumni
Gettysburg may refer to: Events * Gettysburg Campaign, a series of American Civil War military engagements in the Main Eastern Theater. ** Battle of Gettysburg, July 1–3 military engagements during the 1863 Gettysburg Campaign ** Retreat from Gettysburg, the Confederate and Union armies' return to the South following the Battle of Gettysburg * Gettysburg Address, President Abraham Lincoln's speech at the November 19, 1863, Consecration of the National Cemetery at Gettysburg. Places ; Pennsylvania-related articles *Gettysburg, Pennsylvania ** Gettysburg Battlefield Historic District, of historic properties, buildings, and structures in Adams County, Pennsylvania ** Gettysburg National Military Park, protected by the National Park Service *** Gettysburg Museum and Visitor Center, the National Park Service's reception center *** Gettysburg National Cemetery, a district of the military park on Cemetery Hill *** Gettysburg National Museum, the 1921 museum used as the 1974-2008 ...
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2005 Deaths
This is a list of lists of deaths of notable people, organized by year. New deaths articles are added to their respective month (e.g., Deaths in ) and then linked below. 2025 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 1986 Earlier years ''Deaths in years earlier than this can usually be found in the main articles of the years.'' See also * Lists of deaths by day * Deaths by year (category) {{DEFAULTSORT:deaths by year ...
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1925 Births
Events January * January 1 – The Syrian Federation is officially dissolved, the State of Aleppo and the State of Damascus having been replaced by the State of Syria (1925–1930), State of Syria. * January 3 – Benito Mussolini makes a pivotal speech in the Italian Chamber of Deputies (Italy), Chamber of Deputies which will be regarded by historians as the beginning of his dictatorship. * January 5 – Nellie Tayloe Ross becomes the first female governor (Wyoming) in the United States. Twelve days later, Ma Ferguson becomes first female governor of Texas. * January 25 – Hjalmar Branting resigns as Prime Minister of Sweden because of ill health, and is replaced by the minister of trade, Rickard Sandler. * January 27–February 1 – The 1925 serum run to Nome (the "Great Race of Mercy") relays diphtheria antitoxin by dog sled across the U.S. Territory of Alaska to combat an epidemic. February * February 25 – Art Gillham records (for Columbia Re ...
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American Physiologists
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label that was previously known as Def American * American University, in Washington, D.C. Sports teams S ...
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Second Messenger
Second messengers are intracellular signaling molecules released by the cell in response to exposure to extracellular signaling molecules—the first messengers. (Intercellular signals, a non-local form of cell signaling, encompassing both first messengers and second messengers, are classified as autocrine, juxtacrine, paracrine, and endocrine depending on the range of the signal.) Second messengers trigger physiological changes at cellular level such as proliferation, differentiation, migration, survival, apoptosis and depolarization. They are one of the triggers of intracellular signal transduction cascades. Examples of second messenger molecules include cyclic AMP, cyclic GMP, inositol triphosphate, diacylglycerol, and calcium. First messengers are extracellular factors, often hormones or neurotransmitters, such as epinephrine, growth hormone, and serotonin. Because peptide hormones and neurotransmitters typically are biochemically hydrophilic molecules, these first mess ...
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Calcium
Calcium is a chemical element; it has symbol Ca and atomic number 20. As an alkaline earth metal, calcium is a reactive metal that forms a dark oxide-nitride layer when exposed to air. Its physical and chemical properties are most similar to its heavier homologues strontium and barium. It is the fifth most abundant element in Earth's crust, and the third most abundant metal, after iron and aluminium. The most common calcium compound on Earth is calcium carbonate, found in limestone and the fossils of early sea life; gypsum, anhydrite, fluorite, and apatite are also sources of calcium. The name comes from Latin ''calx'' " lime", which was obtained from heating limestone. Some calcium compounds were known to the ancients, though their chemistry was unknown until the seventeenth century. Pure calcium was isolated in 1808 via electrolysis of its oxide by Humphry Davy, who named the element. Calcium compounds are widely used in many industries: in foods and pharmaceuticals for ...
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Parathyroid Hormone
Parathyroid hormone (PTH), also called parathormone or parathyrin, is a peptide hormone secreted by the parathyroid glands that regulates serum calcium and phosphate through its actions on the bone, kidneys, and small intestine. PTH increases serum calcium levels and is counteracted by calcitonin. Additionally, it promotes the synthesis of calcitriol, the active form of vitamin D. PTH influences bone remodeling, which is an ongoing process in which bone tissue is alternately resorbed and rebuilt over time. PTH is secreted in response to low blood serum calcium (Ca2+) levels. PTH indirectly stimulates osteoclast activity within the bone matrix ( osteon), in an effort to release more ionic calcium (Ca2+) into the blood to elevate a low serum calcium level. The bones store calcium from which the body can release into the blood as needed as needed to keep the amount of calcium in the blood at appropriate levels despite the ever-present challenges of metabolism, ...
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