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Haplogroup O (mtDNA)
Haplogroup O mtDNA is a haplogroup derived from haplogroup N and found in Oceania. Specifically, it is found among Aboriginal Australians. Its defining mutations are G6755A, C9140T, and G16213A. It is one of the rarest haplogroups. As of 2022, FamilyTreeDNA reports that only 4 people in their customer base who have tested their complete mitochondrial sequences are members of the haplogroup. YFull reports 9 known members, 8 of whom are stated to be from Australia, and that the haplogroup is at least 20,000 years old. The following table lists relevant GenBank samples: Subclades Tree * O ** O-a1 *** O-a1a ** O1 *** O-a2 ** O1 *** O1a Notes See also *Genealogical DNA test *Genetic genealogy *Human mitochondrial genetics *Population genetics *Human mitochondrial DNA haplogroups In human genetics, a human mitochondrial DNA haplogroup is a haplogroup defined by differences in Human mitochondrial genetics, human mitochondrial DNA. Haplogroups are used to represent the major ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Mitochondrial DNA Haplogroups
In human genetics, a human mitochondrial DNA haplogroup is a haplogroup defined by differences in Human mitochondrial genetics, human mitochondrial DNA. Haplogroups are used to represent the major branch points on the mitochondrial phylogenetic tree. Understanding the evolutionary path of the female lineage has helped population geneticists trace the matrilineality, matrilineal inheritance of modern humans back to human origins in Africa and the subsequent spread around the globe. The letter names of the haplogroups (not just mitochondrial DNA haplogroups) run from A to Z. As haplogroups were named in the order of their discovery, the alphabetical ordering does not have any meaning in terms of actual genetic relationships. The hypothetical woman at the root of all these groups (meaning just the mitochondrial DNA haplogroups) is the matrilineal most recent common ancestor, most recent common ancestor (MRCA) for world population, all currently living humans. She is commonly called ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MtDNA
Mitochondrial DNA (mtDNA and mDNA) is the DNA located in the mitochondria organelles in a eukaryotic cell that converts chemical energy from food into adenosine triphosphate (ATP). Mitochondrial DNA is a small portion of the DNA contained in a eukaryotic cell; most of the DNA is in the cell nucleus, and, in plants and algae, the DNA also is found in plastids, such as chloroplasts. Mitochondrial DNA is responsible for coding of 13 essential subunits of the complex oxidative phosphorylation (OXPHOS) system which has a role in cellular energy conversion. Human mitochondrial DNA was the first significant part of the human genome to be sequenced. This sequencing revealed that human mtDNA has 16,569 base pairs and encodes 13 proteins. As in other vertebrates, the human mitochondrial genetic code differs slightly from nuclear DNA. Since animal mtDNA evolves faster than nuclear genetic markers, it represents a mainstay of phylogenetics and evolutionary biology. It also permits tra ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Haplogroup N (mtDNA)
Haplogroup N is a human mitochondrial DNA (mtDNA) clade. A macrohaplogroup, its descendant lineages are distributed across many continents. Like its sibling macrohaplogroup M, macrohaplogroup N is a descendant of the haplogroup L3. All mtDNA haplogroups found outside of Africa are descendants of either haplogroup N or its sibling haplogroup M. M and N are the signature maternal haplogroups that define the theory of the recent African origin of modern humans and subsequent early human migrations around the world. The global distribution of haplogroups N and M indicates that there was likely at least one major prehistoric migration of humans out of Africa, with both N and M later evolving outside the continent. Origins There is widespread agreement in the scientific community concerning the African ancestry of haplogroup L3 (haplogroup N's parent clade). However, whether or not the mutations which define haplogroup N itself first occurred within Asia or Africa has been a subject ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oceania
Oceania ( , ) is a region, geographical region including Australasia, Melanesia, Micronesia, and Polynesia. Outside of the English-speaking world, Oceania is generally considered a continent, while Mainland Australia is regarded as its continental landmass. Spanning the Eastern Hemisphere, Eastern and Western Hemisphere, Western hemispheres, at the centre of the land and water hemispheres, water hemisphere, Oceania is estimated to have a land area of about and a population of around 46.3 million as of 2024. Oceania is the smallest continent in land area and the list of continents and continental subregions by population, second-least populated after Antarctica. Oceania has a diverse mix of economies from the developed country, highly developed and globally competitive market economy, financial markets of Australia, French Polynesia, Hawaii, New Caledonia, and New Zealand, which rank high in quality of life and Human Development Index, to the much least developed countries ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aboriginal Australians
Aboriginal Australians are the various indigenous peoples of the Mainland Australia, Australian mainland and many of its islands, excluding the ethnically distinct people of the Torres Strait Islands. Humans first migrated to Australia (continent), Australia 50,000 to 65,000 years ago, and over time formed as many as 500 List of Aboriginal Australian group names, language-based groups. In the past, Aboriginal people lived over large sections of the continental shelf. They were isolated on many of the smaller offshore islands and Tasmania when the land was inundated at the start of the Holocene Interglacial, inter-glacial period, about 11,700 years ago. Despite this, Aboriginal people maintained extensive networks within the continent and certain groups maintained relationships with Torres Strait Islanders and the Makassar people, Makassar people of modern-day Indonesia. Over the millennia, Aboriginal people developed complex trade networks, inter-cultural relationships, law ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Family Tree DNA
FamilyTreeDNA is a division of Gene by Gene, a commercial genetic testing company based in Houston, Texas. FamilyTreeDNA offers analysis of autosomal DNA, Y-DNA, and mitochondrial DNA to individuals for genealogical purpose. With a database of more than two million records, it is the most popular company worldwide for Y-DNA and mitochondrial DNA, and the fourth most popular for autosomal DNA. In Europe, it is the most common also for autosomal DNA. FamilyTreeDNA as a division of Gene by Gene were acquired by MYDNA, Inc., an Australian company, in January 2021. History Concept and founding (2000–2002) FamilyTreeDNA was founded based on an idea conceived by Bennett Greenspan, a lifelong entrepreneur and genealogy enthusiast. In 1999, Greenspan had entered semi-retirement and was working on his family history. He began work on his mother's Nitz lineage. When faced with a roadblock in his work, he remembered two cases of genetics being used to prove ancestry that had rece ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
GenBank
The GenBank sequence database is an open access, annotated collection of all publicly available nucleotide sequences and their protein translations. It is produced and maintained by the National Center for Biotechnology Information (NCBI; a part of the National Institutes of Health in the United States) as part of the International Nucleotide Sequence Database Collaboration (INSDC). In October 2024, GenBank contained 34 trillion base pairs from over 4.7 billion nucleotide sequences and more than 580,000 formally described species. The database started in 1982 by Walter Goad and Los Alamos National Laboratory. GenBank has become an important database for research in biological fields and has grown in recent years at an exponential rate by doubling roughly every 18 months. GenBank is built by direct submissions from individual laboratories, as well as from bulk submissions from large-scale sequencing centers. Submissions Only original sequences can be submitted to GenBank. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Queensland
Queensland ( , commonly abbreviated as Qld) is a States and territories of Australia, state in northeastern Australia, and is the second-largest and third-most populous state in Australia. It is bordered by the Northern Territory, South Australia and New South Wales to the west, south-west and south, respectively. To the east, Queensland is bordered by the Coral Sea and the Pacific Ocean; to the state's north is the Torres Strait, separating the Australian mainland from Papua New Guinea, and the Gulf of Carpentaria to the north-west. With an area of , Queensland is the world's List of country subdivisions by area, sixth-largest subnational entity; it List of countries and dependencies by area, is larger than all but 16 countries. Due to its size, Queensland's geographical features and climates are diverse, and include tropical rainforests, rivers, coral reefs, mountain ranges and white sandy beaches in its Tropical climate, tropical and Humid subtropical climate, sub-tropical c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Northern Territory
The Northern Territory (abbreviated as NT; known formally as the Northern Territory of Australia and informally as the Territory) is an states and territories of Australia, Australian internal territory in the central and central-northern regions of Australia. The Northern Territory shares its borders with Western Australia to the west (129th meridian east), South Australia to the south (26th parallel south), and Queensland to the east (138th meridian east). To the north, the Northern Territory looks out to the Timor Sea, the Arafura Sea, and the Gulf of Carpentaria, including Western New Guinea and various other islands of the Indonesian archipelago. The NT covers , making it the third-largest Australian federal division, and List of country subdivisions by area, the 11th-largest country subdivision in the world. It is sparsely populated, with a population of only 249,000 – fewer than half the population of Tasmania. The largest population centre is the capital city of Darw ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genealogical DNA Test
A genealogical DNA test is a DNA-based Genetic testing, genetic test used in genetic genealogy that looks at specific locations of a person's genome in order to find or verify ancestral genealogical relationships, or (with lower reliability) to estimate the ethnicity, ethnic mixture of an individual. Since different testing companies use different ethnic reference groups and different matching algorithms, ethnicity estimates for an individual vary between tests, sometimes dramatically. Three principal types of genealogical DNA tests are available, with each looking at a different part of the genome and being useful for different types of genealogical research: Genealogical DNA test#Autosomal DNA (atDNA) testing, autosomal (atDNA), Genealogical DNA test#Mitochondrial DNA (mtDNA) testing, mitochondrial (mtDNA), and Genealogical DNA test#Y-chromosome (Y-DNA) testing, Y-chromosome (Y-DNA). Autosomal tests may result in a large number of DNA matches to both males and females who have ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genetic Genealogy
Genetic genealogy is the use of genealogical DNA tests, i.e., DNA profiling and DNA testing, in combination with traditional genealogical methods, to infer genetic relationships between individuals. This application of genetics came to be used by family historians in the 21st century, as DNA tests became affordable. The tests have been promoted by amateur groups, such as Surname DNA project, surname study groups or regional genealogical groups, as well as research projects such as the Genographic Project. about 30 million people had been tested. As the field developed, the aims of practitioners broadened, with many seeking knowledge of their ancestry beyond the recent centuries, for which traditional pedigrees can be constructed. History The investigation of surnames in genetics Genetics is the study of genes, genetic variation, and heredity in organisms.Hartl D, Jones E (2005) It is an important branch in biology because heredity is vital to organisms' evolution. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Mitochondrial Genetics
Human mitochondrial genetics is the study of the genetics of human mitochondrial DNA (the DNA contained in human mitochondria). The human mitochondrial genome is the entirety of hereditary information contained in human mitochondria. Mitochondria are small structures in cells that generate energy for the cell to use, and are hence referred to as the "powerhouses" of the cell. Mitochondrial DNA (mtDNA) is not transmitted through nuclear DNA (nDNA). In humans, as in most multicellular organisms, mitochondrial DNA is inherited only from the mother's ovum. There are theories, however, that paternal mtDNA transmission in humans can occur under certain circumstances. Mitochondrial inheritance is therefore non-Mendelian, as Mendelian inheritance presumes that half the genetic material of a fertilized egg (zygote) derives from each parent. This allowed the creation of mitochondrial DNA haplogroups to study population genetics. Eighty percent of mitochondrial DNA codes for mitocho ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
