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Haplogroup L (mtDNA)
In human mitochondrial genetics, L is the mitochondrial DNA macro-haplogroup that is at the root of the anatomically modern human (''Homo sapiens'') mtDNA phylogenetic tree. As such, it represents the most ancestral mitochondrial lineage of all currently living modern humans, also dubbed " Mitochondrial Eve". Its two sub-clades are L1-6 and L0. The split occurred during the Penultimate Glacial Period; L1-6 is estimated to have formed ca. 170 kya, and L0 ca. 150 kya. The formation of L0 is associated with the peopling of Southern Africa by populations ancestral to the Khoisan, ca. 140 kya, at the onset of the Eemian interglacial. L is further subdivided into L1-6 and L1, dated ca. 150 kya and 130 kya, respectively. Haplogroups L5 (120 kya), L2 and L6 (90 kya), L4 (80 kya) and L3 (70 kya). Origin The outgroup for mtDNA phylogeny of modern humans is the mtDNA of archaic humans, specifically Neanderthals and Denisovans. The split of the modern human lineage f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Haplogroup L5 (mtDNA)
Haplogroup L5 is a human mitochondrial DNA (mtDNA) clade. It was previously known as L1e. Distribution L5 is a small haplogroup centered in East Africa. The highest frequency is in Mbuti Pygmies from Eastern Central Africa at 15%. It is present in relatively small frequencies in Tanzania ( Sandawe and others), Kenya, Chad, Ethiopia, Sudan, Nubia, EgyptSample UPE52 is subclade L5a. and Saudi Arabia. Haplogroup L5 has been observed among specimens at the island cemetery in Kulubnarti, Sudan Sudan, officially the Republic of the Sudan, is a country in Northeast Africa. It borders the Central African Republic to the southwest, Chad to the west, Libya to the northwest, Egypt to the north, the Red Sea to the east, Eritrea and Ethiopi ..., which date from the Early Christian period (AD 550–800). Subclades Tree This phylogenetic tree of haplogroup L5 subclades is based on the paper by Mannis van Oven and Manfred Kayser ''Updated comprehensive phylogenetic tree of global hum ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Haplogroup L7 (mtDNA)
Haplogroup L4 is a Human mitochondrial DNA haplogroup, human mitochondrial DNA (mtDNA) haplogroup. It is a small maternal clade primarily restricted to Africa. L4 is important in East Africa. The highest frequencies are in Tanzania among the Hadza people, Hadza at 60-83% and Sandawe people, Sandawe at 48%. It has two branches, L4a and L4b. Subgroup L4a was formerly called L7 and considered a separate subclade of Haplogroup L3-4 (mtDNA), L3'4'7. It has been recognized as a subclade of L4, with Haplogroup L3 (mtDNA), L3 as its outgroup by Behar et al. (2008). The parent clade L3'4 is to have emerged at 106–66 kya. L4 is not much later than this, estimated at 87 kya by Fernandes et al. (2015).Fernandes V, Triska P, Pereira JB, Alshamali F, Rito T, Machado A, et al. (2015) Genetic Stratigraphy of Key Demographic Events in Arabia. PLoS ONE 10(3): e0118625. Phylogeny The following phylogeny is based on van Oven and Kayser (2008). *Haplogroup L3'4 (mtDNA), L3'4 **L4 *** L4 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Eastern Africa
East Africa, also known as Eastern Africa or the East of Africa, is a region at the eastern edge of the Africa, African continent, distinguished by its unique geographical, historical, and cultural landscape. Defined in varying scopes, the region is recognized in the United Nations Statistics Division United Nations geoscheme for Africa, scheme as encompassing 18 sovereign states and 4 territories. It includes the Horn of Africa to the North and Southeastern Africa to the south. Definitions In a narrow sense, particularly in English-speaking contexts, East Africa refers to the area comprising Kenya, Tanzania, and Uganda, largely due to their shared history under the Omani Empire and as parts of the British East Africa Protectorate and German East Africa. Further extending East Africa's definition, the Horn of Africa—comprising Djibouti, Eritrea, Ethiopia, and Somalia—stands out as a distinct geopolitical entity within East Africa.Robert Stock, ''Africa South of the Sahara, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Most Recent Common Ancestor
A most recent common ancestor (MRCA), also known as a last common ancestor (LCA), is the most recent individual from which all organisms of a set are inferred to have descended. The most recent common ancestor of a higher taxon is generally assumed to have been a species. The term is also used in reference to the ancestry of groups of genes (haplotypes) rather than organisms. The ancestry of a set of individuals can sometimes be determined by referring to an established pedigree, although this may refer only to patrilineal or matrilineal lines for sexually-reproducing organisms with two parents, four grandparents, etc. However, in general, it is impossible to identify the exact MRCA of a large set of individuals, but an estimate of the time at which the MRCA lived can often be given. Such ''time to most recent common ancestor'' (''TMRCA'') estimates can be given based on DNA test results and established mutation rates as practiced in genetic genealogy, or by reference to a non- ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jebel Irhoud
Jebel Irhoud or Adrar n Ighoud (; , Moroccan Arabic: ), is an archaeological site located just north of the town of Ighoud, Tlet Ighoud in Youssoufia Province, approximately south-east of the city of Safi, Morocco, Safi in Morocco. It is noted for the hominin fossils that have been found there since the discovery of the site in 1961. Originally thought to be Neanderthals, the specimens have since been assigned to ''Homo sapiens'' and, as reported in 2017, have been dated to roughly 300,000 years ago ( for the Irhoud 3 mandible, based on other fossils and the flint artefacts found nearby). * * "Here we report the ages, determined by thermoluminescence dating, of fire-heated flint artefacts obtained from new excavations at the Middle Stone Age site of Jebel Irhoud, Morocco, which are directly associated with newly discovered remains of H. sapiens8. A weighted average age places these Middle Stone Age artefacts and fossils at 315 ± 34 thousand years ago. Support is obtained th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Interbreeding Between Archaic And Modern Humans
Interbreeding between archaic and modern humans occurred during the Middle Paleolithic and early Upper Paleolithic. The interbreeding happened in several independent events that included Neanderthals and Denisovans, as well as several unidentified hominins. In Europe, Asia and North Africa, interbreeding between archaic humans and Early modern human, modern humans took place several times. The introgression events into modern humans are estimated to have happened about 47,000–65,000 years ago with Neanderthals and about 44,000–54,000 years ago with Denisovans. Neanderthal-derived DNA has been found in the genomes of most contemporary populations, varying noticeably by region. It accounts for 1–4% of modern genomes for people outside Sub-Saharan Africa, although estimates vary, and either none or up to 0.3% for those in Sub-Saharan Africa. Cushitic-speaking peoples, Cushitic and Semitic languages, Semitic speaking populations from the Horn of Africa (such as Ethiopians), wh ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Y-chromosome DNA Haplogroup
In human genetics, a human Y-chromosome DNA haplogroup is a haplogroup defined by specific mutations in the non-Genetic recombination, recombining portions of DNA on the male-specific Y chromosome (Y-DNA). Individuals within a haplogroup share similar numbers of short tandem repeats (STRs) and single-nucleotide polymorphisms (SNPs). The Y-chromosome accumulates approximately two mutations per generation, "one mutation in every 30 million base pairs" and Y-DNA haplogroups represent significant branches of the Y-chromosome phylogenetic tree, each characterized by hundreds or even thousands of unique mutations. The Y-chromosomal most recent common ancestor (Y-MRCA), often referred to as Y-chromosomal Adam, is the most recent common ancestor from whom all currently living humans are descended Patrilineality, patrilineally. Y-chromosomal Adam is estimated to have lived around 236,000 years ago in Africa. By examining other population bottlenecks, most Eurasian men trace their descent ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Denisovans
The Denisovans or Denisova hominins ( ) are an extinct species or subspecies of archaic human that ranged across Asia during the Lower Paleolithic, Lower and Middle Paleolithic, and lived, based on current evidence, from 285 thousand to 25 thousand years ago. Denisovans are known from few physical remains; consequently, most of what is known about them comes from DNA evidence. No formal species name has been established pending more complete fossil material. The first identification of a Denisovan individual occurred in 2010, based on mitochondrial DNA (mtDNA) extracted from a Juvenile (organism), juvenile finger bone excavated from the Siberian Denisova Cave in the Altai Mountains in 2008. Nuclear DNA indicates close affinities with Neanderthals. The cave was also periodically inhabited by Neanderthals, but it is unclear whether Neanderthals and Denisovans ever cohabited in the cave. Additional specimens from Denisova Cave were subsequently identified, as was a single specimen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neanderthals
Neanderthals ( ; ''Homo neanderthalensis'' or sometimes ''H. sapiens neanderthalensis'') are an extinction, extinct group of archaic humans who inhabited Europe and Western and Central Asia during the Middle Pleistocene, Middle to Late Pleistocene. Neanderthal extinction occurred roughly 40,000 years ago with the immigration of modern humans (Cro-Magnons), but Neanderthals in Gibraltar may have persisted for thousands of years longer. The first recognised Neanderthal fossil, Neanderthal 1, was discovered in 1856 in the Neander Valley, Germany. At first, Neanderthal 1 was considered to be one of the racial hierarchy, lower races in accord with historical race concepts. As more fossils were discovered through the early 20th century, Neanderthals became characterised most especially by Marcellin Boule as a unique species of underdeveloped human. By the mid-20th century, human evolution was described as progressing from an apelike ancestor, through a "Neanderthal phase", ending ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Archaic Humans
''Homo'' () is a genus of great ape (family Hominidae) that emerged from the genus ''Australopithecus'' and encompasses only a single extant species, ''Homo sapiens'' (modern humans), along with a number of extinct species (collectively called archaic humans) classified as either ancestral or closely related to modern humans; these include '' Homo erectus'' and '' Homo neanderthalensis''. The oldest member of the genus is '' Homo habilis'', with records of just over 2 million years ago. ''Homo'', together with the genus '' Paranthropus'', is probably most closely related to the species '' Australopithecus africanus'' within ''Australopithecus''.'''' The closest living relatives of ''Homo'' are of the genus '' Pan'' ( chimpanzees and bonobos), with the ancestors of ''Pan'' and ''Homo'' estimated to have diverged around 5.7–11 million years ago during the Late Miocene. ''H. erectus'' appeared about 2 million years ago and spread throughout Africa (debatab ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Haplogroup L3 (mtDNA)
Haplogroup L3 is a Human mitochondrial DNA haplogroup, human mitochondrial DNA (mtDNA) haplogroup. The clade has played a pivotal role in the early dispersal of anatomically modern humans. It is strongly associated with the Southern Dispersal, out-of-Africa migration of modern humans of about 70–50,000 years ago. It is inherited by all modern non-African populations, as well as by some populations in Africa. Origin Haplogroup L3 arose close to 70,000 years ago, near the time of the Southern Dispersal, recent out-of-Africa event. This dispersal originated in East Africa and expanded to West Asia, and further to South and Southeast Asia in the course of a few millennia, and some research suggests that L3 participated in this migration out of Africa. A 2007 estimate for the age of L3 suggested a range of 104–84,000 years ago. More recent analyses, including Soares et al. (2012) arrive at a more recent date, of roughly 70–60,000 years ago. Soares et al. also suggest that L3 m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
