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Hans Selye
János Hugo Bruno "Hans" Selye (; ; January 26, 1907 – October 16, 1982) was a Hungarian-Canadian endocrinologist who conducted important scientific work on the hypothetical non-specific response of an organism to stressors. Although he did not recognize all of the many aspects of glucocorticoids, Selye was aware of their role in the stress response. Biography Selye was born in Vienna, Austria-Hungary on January 26, 1907, and grew up in Komárom (the town with Hungarian majority in present-day Slovakia was cut by the Treaty of Trianon in 1920). Selye's father was a doctor of Hungarian ethnicity and his mother was Austrian. He became a Doctor of Medicine and Chemistry in Prague in 1929 and went on to do pioneering work in stress and endocrinology at Johns Hopkins University, McGill University, and the Université de Montréal. He was nominated for the Nobel Prize in Physiology or Medicine for the first time in 1949. Although he received a total of 17 nominations (1949–195 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Austria-Hungary
Austria-Hungary, also referred to as the Austro-Hungarian Empire, the Dual Monarchy or the Habsburg Monarchy, was a multi-national constitutional monarchy in Central Europe#Before World War I, Central Europe between 1867 and 1918. A military and diplomatic alliance, it consisted of two sovereign states with a single monarch who was titled both the Emperor of Austria and the King of Hungary. Austria-Hungary constituted the last phase in the constitutional evolution of the Habsburg monarchy: it was formed with the Austro-Hungarian Compromise of 1867 in the aftermath of the Austro-Prussian War, following wars of independence by Hungary in opposition to Habsburg rule. It was dissolved shortly after Dissolution of Austria-Hungary#Dissolution, Hungary terminated the union with Austria in 1918 at the end of World War 1. One of Europe's major powers, Austria-Hungary was geographically the second-largest country in Europe (after Russian Empire, Russia) and the third-most populous (afte ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medicine
Medicine is the science and Praxis (process), practice of caring for patients, managing the Medical diagnosis, diagnosis, prognosis, Preventive medicine, prevention, therapy, treatment, Palliative care, palliation of their injury or disease, and Health promotion, promoting their health. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention (medical), prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, medical genetics, genetics, and medical technology to diagnosis (medical), diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, splint (medicine), external splints and traction, medical devices, biologic medical product, biologics, and Radiation (medicine), ionizing radiation, amongst others. Medicine has been practiced since Prehistoric medicine, prehistoric times, and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Adrenal Cortex
The adrenal cortex is the outer region and also the largest part of the adrenal gland. It is divided into three separate zones: zona glomerulosa, zona fasciculata and zona reticularis. Each zone is responsible for producing specific hormones. It is also a secondary site of androgen synthesis. Layers The adrenal cortex comprises three main zones, or layers that are regulated by distinct hormones as noted below. This ''anatomic zonation'' can be appreciated at the microscopic level, where each zone can be recognized and distinguished from one another based on structural and anatomic characteristics. Zona glomerulosa The outermost layer, the zona glomerulosa is the main site for the production of aldosterone, a mineralocorticoid. The synthesis and secretion of aldosterone are mainly regulated by the renin–angiotensin–aldosterone system. The zona glomerulosa cells express a specific enzyme aldosterone synthase (also known as CYP11B2). Aldosterone is largely responsible ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stress (biology)
Stress, whether physiological, biological or psychological, is an organism's response to a stressor, such as an environmental condition or change in life circumstances. When stressed by stimuli that alter an organism's environment, multiple systems respond across the body. In humans and most mammals, the autonomic nervous system and Hypothalamic–pituitary–adrenal axis, hypothalamic-pituitary-adrenal (HPA) axis are the two major systems that respond to stress. Two well-known hormones that humans produce during stressful situations are adrenaline and cortisol. The Sympathoadrenal system, sympathoadrenal medullary axis (SAM) may activate the fight-or-flight response through the sympathetic nervous system, which dedicates energy to more relevant bodily systems to Acute stress reaction, acute adaptation to stress, while the parasympathetic nervous system returns the body to homeostasis. The second major physiological stress-response center, the HPA axis, regulates the release ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
General Adaptation Syndrome
Stress, whether physiological, biological or psychological, is an organism's response to a stressor, such as an environmental condition or change in life circumstances. When stressed by stimuli that alter an organism's environment, multiple systems respond across the body. In humans and most mammals, the autonomic nervous system and hypothalamic-pituitary-adrenal (HPA) axis are the two major systems that respond to stress. Two well-known hormones that humans produce during stressful situations are adrenaline and cortisol. The sympathoadrenal medullary axis (SAM) may activate the fight-or-flight response through the sympathetic nervous system, which dedicates energy to more relevant bodily systems to acute adaptation to stress, while the parasympathetic nervous system returns the body to homeostasis. The second major physiological stress-response center, the HPA axis, regulates the release of cortisol, which influences many bodily functions, such as metabolic, psych ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
James Collip
James Bertram Collip (November 20, 1892 – June 19, 1965) was a Canadian biochemist who was part of the Toronto group which isolated insulin. He served as the chair of the department of biochemistry at McGill University from 1928 to 1941 and dean of medicine at the University of Western Ontario from 1947 to 1961, where he was a charter member of The Kappa Alpha Society. Education Born in Belleville, Ontario, he enrolled at Trinity College at the University of Toronto at the age of 15, and studied physiology and biochemistry. He obtained a Ph.D. in biochemistry from the same university in 1916. Career In 1915, at the age of 22, Collip accepted a lecturing position in Edmonton in the department of physiology at the University of Alberta Faculty of Medicine, shortly before completing his doctorate. He fulfilled the role for 7 years, eventually rising to the position of professor and head of the department of biochemistry in 1922. His research at the time was mainly focused o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Baltimore
Baltimore is the most populous city in the U.S. state of Maryland. With a population of 585,708 at the 2020 census and estimated at 568,271 in 2024, it is the 30th-most populous U.S. city. The Baltimore metropolitan area is the 20th-largest metropolitan area in the country at 2.84 million residents. The city is also part of the Washington–Baltimore combined statistical area, which had a population of 9.97 million in 2020. Baltimore was designated as an independent city by the Constitution of Maryland in 1851. Though not located under the jurisdiction of any county in the state, it forms part of the central Maryland region together with the surrounding county that shares its name. The land that is present-day Baltimore was used as hunting ground by Paleo-Indians. In the early 1600s, the Susquehannock began to hunt there. People from the Province of Maryland established the Port of Baltimore in 1706 to support the tobacco trade with Europe and established the Town ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Charles University
Charles University (CUNI; , UK; ; ), or historically as the University of Prague (), is the largest university in the Czech Republic. It is one of the List of oldest universities in continuous operation, oldest universities in the world in continuous operation, the oldest university north of the Alps and east of University of Paris, Paris. Today, the university consists of 17 faculties located in Prague, Hradec Králové, and Plzeň. History Medieval university (1349–1419) The establishment of a medieval university in Prague was inspired by Holy Roman Emperor Charles IV, Holy Roman Emperor, Charles IV. He requested his friend and ally, Pope Clement VI, to create the university. On 26 January 1347, the pope issued the bull establishing a university in Prague, modeled on the University of Paris, with all four faculty (division), faculties, including theology. On 7 April 1348 Charles, the king of Bohemia, gave to the established university privileges and immunities from the se ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hans Selye
János Hugo Bruno "Hans" Selye (; ; January 26, 1907 – October 16, 1982) was a Hungarian-Canadian endocrinologist who conducted important scientific work on the hypothetical non-specific response of an organism to stressors. Although he did not recognize all of the many aspects of glucocorticoids, Selye was aware of their role in the stress response. Biography Selye was born in Vienna, Austria-Hungary on January 26, 1907, and grew up in Komárom (the town with Hungarian majority in present-day Slovakia was cut by the Treaty of Trianon in 1920). Selye's father was a doctor of Hungarian ethnicity and his mother was Austrian. He became a Doctor of Medicine and Chemistry in Prague in 1929 and went on to do pioneering work in stress and endocrinology at Johns Hopkins University, McGill University, and the Université de Montréal. He was nominated for the Nobel Prize in Physiology or Medicine for the first time in 1949. Although he received a total of 17 nominations (1949–195 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hungarian Revolution Of 1956
The Hungarian Revolution of 1956 (23 October – 4 November 1956; ), also known as the Hungarian Uprising, was an attempted countrywide revolution against the government of the Hungarian People's Republic (1949–1989) and the policies caused by the government's subordination to the Soviet Union (USSR). The uprising lasted 15 days before being crushed by Soviet tanks and troops on 7 November 1956 (outside of Budapest firefights lasted until at least 12 November 1956).Granville, Johanna. The First Domino: International Decision Making During the Hungarian Crisis of 1956, pp. 94-195. Thousands were killed or wounded, and nearly a quarter of a million Hungarians fled the country. The Hungarian Revolution began on 23 October 1956 in Budapest when university students appealed to the civil populace to join them at the Hungarian Parliament Building to protest against the USSR's geopolitical domination of Hungary through the Stalinist government of Mátyás Rákosi. A delegation of s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Slovakia
Slovakia, officially the Slovak Republic, is a landlocked country in Central Europe. It is bordered by Poland to the north, Ukraine to the east, Hungary to the south, Austria to the west, and the Czech Republic to the northwest. Slovakia's mostly mountainous territory spans about , hosting a population exceeding 5.4 million. The capital and largest city is Bratislava, while the second largest city is Košice. The Slavs arrived in the territory of the present-day Slovakia in the 5th and 6th centuries. From the late 6th century, parts of modern Slovakia were incorporated into the Pannonian Avars, Avar Khaghanate. In the 7th century, the Slavs played a significant role in the creation of Samo's Empire. When the Avar Khaghanate dissolved in the 9th century, the Slavs established the Principality of Nitra before it was annexed by the Great Moravia, Principality of Moravia, which later became Great Moravia. When Great Moravia fell in the 10th century, the territory was integrated i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University
A university () is an educational institution, institution of tertiary education and research which awards academic degrees in several Discipline (academia), academic disciplines. ''University'' is derived from the Latin phrase , which roughly means "community of teachers and scholars". Universities typically offer both undergraduate education, undergraduate and postgraduate education, postgraduate programs. The first universities in Europe were established by Catholic Church, Catholic monks. The University of Bologna (), Italy, which was founded in 1088, is the first university in the sense of: *being a high degree-awarding institute. *using the word (which was coined at its foundation). *having independence from the ecclesiastic schools and issuing secular as well as non-secular degrees (with teaching conducted by both clergy and non-clergy): grammar, rhetoric, logic, theology, canon law and notarial law.Hunt Janin: "The university in medieval life, 1179–1499", McFarland, 2 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
