HLA-A36
Distribution A36 is largely limited to Africa. Outside Africa, more than half of the populations have no A36 and the majority that do, have only trace levels. The exception is in Central/East Central Asia. This appears not to be coincidental. HLA DR3-DQ2 linkage and frequency indicates a strong possibility of a recent migration from either North or West Africa in which the DR3-DQ2 (notably DRB1*0302) and A*33-B*58 haplotype A haplotype (haploid genotype) is a group of alleles in an organism that are inherited together from a single parent. Many organisms contain genetic material (DNA) which is inherited from two parents. Normally these organisms have their DNA orga ...s were carried into and redistributed from Central Asia into the surrounding populations. References {{HLA-A serotypes 3 ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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HLA DR3-DQ2
HLA DR3-DQ2 is a double serotype that specifically recognizes cells from individuals who carry a multigene HLA DR, DQ haplotype. Certain HLA DR and DQ genes have known involvement in autoimmune diseases. DR3- DQ2, a multigene haplotype, stands out in prominence because it is a factor in several prominent diseases, namely coeliac disease and juvenile diabetes. In coeliac disease, the DR3-DQ2 haplotype is associated with highest risk for disease in first degree relatives, highest risk is conferred by DQA1*0501:DQB1*0201 homozygotes and semihomozygotes of DQ2, and represents the overwhelming majority of risk. HLA DR3-DQ2 encodes DQ2.5cis isoform of HLA-DQ, this isoform is described frequently as 'the DQ2 isoform', but in actuality there are two major DQ2 isoform. The DQ2.5 isoform, however, is many times more frequently associated with autoimmune disease, and as a result to contribution of DQ2.2 is often ignored. The frequency of both diseases changes concerning both the env ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Mossi People
The Mossi or Mosi are a Gur languages, Gur ethnic group native to modern Burkina Faso, primarily the Volta River basin. The Mossi are the largest ethnic group in Burkina Faso, constituting 52% of the population, or about 11.1 million people. The other 48% of Burkina Faso's population is composed of more than 60 ethnic groups, mainly the Gurunsi people, Gurunsi, Senufo people, Senufo, Lobi people, Lobi, Bobo people, Bobo, Bissa people, Bissa and Fula people, Fulani. The Mossi speak the Mòoré language. History The Mossi people originated in Burkina Faso, although significant numbers of Mossi live in neighboring countries, including Benin, Côte d'Ivoire, Ghana, Mali, and Togo. In 2022, the estimated population of Burkina Faso was 20M+, over 11M of which are Mossi. Another 2 million Mossi live in Côte d'Ivoire. Origins According to oral tradition, the Mossi come from the marriage of a Mamprusi/Dagomba princess, Yennenga, and a Mandé hunter. Yennenga was a warrior princess, dau ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Burkina Faso
Burkina Faso is a landlocked country in West Africa, bordered by Mali to the northwest, Niger to the northeast, Benin to the southeast, Togo and Ghana to the south, and Ivory Coast to the southwest. It covers an area of 274,223 km2 (105,878 sq mi). In 2024, the country had an estimated population of approximately 23,286,000. Previously called the Republic of Upper Volta (1958–1984), it was Geographical renaming, renamed Burkina Faso by then-List of heads of state of Burkina Faso, president Thomas Sankara. Its citizens are known as Burkinabes, and its Capital city, capital and largest city is Ouagadougou. The largest ethnic group in Burkina Faso is the Mossi people, who settled the area in the 11th and 13th centuries. They established powerful Mossi Kingdoms, kingdoms such as Ouagadougou, Tenkodogo, and Yatenga. In 1896, it was Colonization, colonized by the French colonial empire, French as part of French West Africa; in 1958, Upper Volta became a self-governing colony wi ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Beti People
The Beti people are a Central African ethnic group primarily found in central Cameroon. They are also found in Equatorial Guinea and northern Gabon. They are closely related to the Bulu people, the Fang people and the Yaunde people, who are all sometimes grouped as Ekang. The Beti are found in northern regions of their joint demographic distributions, the Fang in the southern regions, and others in between. Estimates of the total Beti population vary, with many sources placing them at over three million spread from the Atlantic coastal regions near Equatorial Guinea into the hilly, equatorial forest covered highlands of central Africa reaching into the Congo. Language The Beti people, like the other Beti-Pahuin peoples speak a dialect of the Fang language, also known as Pahuin or Pangwe. Sometimes called as the Beti language, it is a Southern Bantu language belonging to the Niger-Congo family of languages. The Beti language is sub-classified as Bulu language, Eton language, ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Cameroon
Cameroon, officially the Republic of Cameroon, is a country in Central Africa. It shares boundaries with Nigeria to the west and north, Chad to the northeast, the Central African Republic to the east, and Equatorial Guinea, Gabon, and the Republic of the Congo to the south. Its coastline lies on the Bight of Biafra, part of the Gulf of Guinea, and the Atlantic Ocean. Due to its strategic position at the crossroads between West Africa and Central Africa, it has been categorized as being in both camps. Cameroon's population of nearly 31 million people speak 250 native languages, in addition to the national tongues of English and French, or both. Early inhabitants of the territory included the Sao civilisation around Lake Chad and the Baka people (Cameroon and Gabon), Baka hunter-gatherers in the southeastern rainforest. Portuguese discoveries, Portuguese explorers reached the coast in the 15th century and named the area ''Rio dos Camarões'' (''Shrimp River''), which became ''C ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Lusaka
Lusaka ( ) is the Capital city, capital and largest city of Zambia. It is one of the fastest-developing cities in southern Africa. Lusaka is in the southern part of the central plateau at an elevation of about . , the city's population was about 3.3 million, while the urban population is estimated at 2.5 million in 2018. Lusaka is the centre of both commerce and government in Zambia and connects to the country's four main highways heading Great North Road, Zambia, north, Livingstone Road, south, Great East Road, east, and Great West Road, Zambia, west. English is the official language of the city administration, while Bemba language, Bemba, Tonga language (Zambia and Zimbabwe), Tonga and Nyanja are the commonly-spoken street languages. The earliest evidence of settlement in the area dates to the 6th century AD, with the first known settlement in the 11th century. It was then home to the Lenje people, Lenje and Soli language, Soli peoples from the 17th or 18th century. The found ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Zambia
Zambia, officially the Republic of Zambia, is a landlocked country at the crossroads of Central Africa, Central, Southern Africa, Southern and East Africa. It is typically referred to being in South-Central Africa or Southern Africa. It is bordered to the north by the Democratic Republic of the Congo, Tanzania to the north-east, Malawi to the east, Mozambique to the southeast, Zimbabwe and Botswana to the south, Namibia to the southwest, and Angola to the west. The capital city of Zambia is Lusaka, located in the south-central part of Zambia. The population is concentrated mainly around Lusaka in the south and the Copperbelt Province to the north, the core economic hubs of the country. Originally inhabited by Khoisan peoples, the region was affected by the Bantu expansion of the thirteenth century. Following European colonization of Africa, European colonisers in the 18th century, the British colonised the region into the British protectorates of Barotziland–North-Western Rho ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Harare
Harare ( ), formerly Salisbury, is the Capital city, capital and largest city of Zimbabwe. The city proper has an area of , a population of 1,849,600 as of the 2022 Zimbabwe census, 2022 census and an estimated 2,487,209 people in its metropolitan province. The city is situated in north-eastern Zimbabwe in the country's Mashonaland region. Harare Metropolitan Province incorporates the city and the municipalities of Chitungwiza, Epworth, Zimbabwe, Epworth and Ruwa. The city sits on a plateau at an elevation of above sea level, and its climate falls into the subtropical highland category. The city was founded in 1890 by the Pioneer Column, a small military force of the British South Africa Company, and was named Southern Rhodesia, Fort Salisbury after the British Prime Minister Robert Gascoyne-Cecil, 3rd Marquess of Salisbury, Lord Salisbury. Company Company rule in Rhodesia, administrators Demarcation line, demarcated the city and ran it until Southern Rhodesia achieved respo ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Shona People
The Shona people () also/formerly known as the Karanga are a Bantu peoples, Bantu ethnic group native to Southern Africa, primarily living in Zimbabwe where they form the majority of the population, as well as Mozambique, South Africa, and worldwide diaspora. There are five major Shona language/dialect clusters: Manyika, Karanga, Zezuru, Korekore, Kalanga, and Ndau. Classification The Shona people are grouped according to the dialect of the language they speak. Their estimated population is 22.6 million: * Korekore people, Korekore (northern region of Zimbabwe) * Zezuru people, Zezuru (central Zimbabwe) * Manyika tribe, Manyika (eastern Zimbabwe around Mutare, Buhera, Nyanga, Zimbabwe, Nyanga and into Mozambique) * Ndau people, Ndau (southeast Zimbabwe around Mutare, Chimanimani, Chipinge and into Mozambique) * Karanga people, Karanga (south-central Zimbabwe around Masvingo) * Kalanga people, Kalanga (southwest Zimbabwe, interspersed with the Northern Ndebele people, Ndebele ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Zimbabwe
file:Zimbabwe, relief map.jpg, upright=1.22, Zimbabwe, relief map Zimbabwe, officially the Republic of Zimbabwe, is a landlocked country in Southeast Africa, between the Zambezi and Limpopo Rivers, bordered by South Africa to the south, Botswana to the southwest, Zambia to the north, and Mozambique to the east. The capital and largest city is Harare, and the second largest is Bulawayo. A country of roughly 16.6 million people as per 2024 census, Zimbabwe's largest ethnic group are the Shona people, Shona, who make up 80% of the population, followed by the Northern Ndebele people, Northern Ndebele and other #Demographics, smaller minorities. Zimbabwe has 16 official languages, with English, Shona language, Shona, and Northern Ndebele language, Ndebele the most common. Zimbabwe is a member of the United Nations, the Southern African Development Community, the African Union, and the Common Market for Eastern and Southern Africa. The region was long inhabited by the San people, ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Uyghurs
The Uyghurs,. alternatively spelled Uighurs, Uygurs or Uigurs, are a Turkic peoples, Turkic ethnic group originating from and culturally affiliated with the general region of Central Asia and East Asia. The Uyghurs are recognized as the titular nationality of the Xinjiang Uyghur Autonomous Region in Northwest China. They are one of Ethnic minorities in China, China's 55 officially recognized ethnic minorities. The Uyghurs have traditionally inhabited a series of Oasis, oases scattered across the Taklamakan Desert within the Tarim Basin. These oases have historically existed as independent states or were controlled by many civilizations including History of China, China, the Mongol Empire, Mongols, the Tibetan Empire, Tibetans, and various Turkic polities. The Uyghurs gradually started to become Islamized in the 10th century, and most Uyghurs identified as Muslims by the 16th century. Islam has since played an important role in Uyghur culture and identity. An estimated 80% ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Bamileke People
The Bamiléké people are an ethnic group of Central Africa that inhabits the Western High Plateau colloquially known as the ''grassfields'' of Cameroon. According to Dr John Feyou de Hapy, Bamiléké means "people of faith". Languages The Bamileke languages are Grassfields languages that belong to the Southern Bantoid branch of the Niger-Congo language family. History Most Bamiléké historical narratives detail an origin along the Nile River in what is now Sudan.People from the land of Ka: Bamiléké History by Alexis Maxime Feyou de Happy; 5 March 2015 A survey examining the methods and instruments of communication among the Bamilekes show a common origin with populations along the Nile. Oral tradition collected by Alexis Maxime Feyou de Happy and his son, Joseph, suggested that the arrival of the Bamiléké in Western Cameroon occurred in multiple waves with two primary routes. The first route originated in the North between the Lake Tchad area and the Nile Valley. ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |