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Gordon M. Shepherd
Gordon Murray Shepherd (21 July 1933 – 9 June 2022) was an American neuroscientist who carried out basic experimental and computational research on how neurons are organized into microcircuits to carry out the functional operations of the nervous system. Using the olfactory system as a model that spans multiple levels of space, time and disciplines, his studies ranged from molecular to behavioral, recognized by an annual lecture at Yale University on "integrative neuroscience". At the time of his death, he was professor of neuroscience emeritus at the Yale School of Medicine. He graduated from Iowa State University with a BA, Harvard Medical School with an MD, and the University of Oxford with a DPhill. Early work His graduate studies in 1963 of the electrophysiology of the olfactory bulb produced one of the first diagrams of a brain microcircuit. Building on this work he collaborated with Wilfrid Rall, just then founding the new field of computational neuroscience, at the Nat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Electron Microscope
An electron microscope is a microscope that uses a beam of electrons as a source of illumination. It uses electron optics that are analogous to the glass lenses of an optical light microscope to control the electron beam, for instance focusing it to produce magnified images or electron diffraction patterns. As the wavelength of an electron can be up to 100,000 times smaller than that of visible light, electron microscopes have a much higher Angular resolution, resolution of about 0.1 nm, which compares to about 200 nm for optical microscope, light microscopes. ''Electron microscope'' may refer to: * Transmission electron microscopy, Transmission electron microscope (TEM) where swift electrons go through a thin sample * Scanning transmission electron microscopy, Scanning transmission electron microscope (STEM) which is similar to TEM with a scanned electron probe * Scanning electron microscope (SEM) which is similar to STEM, but with thick samples * Electron microprobe sim ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Frédéric Morin
Joe Beef is a restaurant in Montreal, Quebec, Canada. The owners describe the cuisine as “Bocusian-Lyonnaise cuisine du marché (French market cuisine).” It is located in the neighbourhood of Little Burgundy, in the borough of Le Sud Ouest. History Joe Beef was opened on September 19, 2005 by David McMillan, Frederic Morin, and Allison Cunningham with financial guidance and investment by Jeff Baikowitz and David Lisbona. The restaurant took over the location of Café Miguel. The restaurant's name is a homage to Montreal's infamous Joe Beef, an alias for Charles McKiernan. McKiernan, who owned a tavern that served many lower-class laborers in Montreal, "died in his canteen of a heart attack at the age of 54." McKiernan's generosity and gluttony may have inspired the concept of Joe Beef restaurant, which challenges the conventions of fine French dining. As of November 25th, 2021 co-founder David McMillan announced his retirement, citing burnout and stress after 32 years in the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dan Han
Dan Han (한동녕) is an American neuroscientist and clinical psychologist, who specializes in neuropsychology, neurotrauma, and neurogastronomy. He is one of the founders of the International Society of Neurogastronomy. He is a Fellow of the American Neurological Association, the Royal Society of Medicine, and of the Royal Society for Public Health. Han is currently a Professor of neurology, neurosurgery, and physical medicine & rehabilitation at the University of Kentucky College of Medicine. Career Han trained in clinical psychology and neuropsychology at Loyola University Chicago, Adler University, University of Chicago, and Rush University, and then completed his fellowship at the Charles Matthews Neuropsychology Lab under Bruce Hermann at the University of Wisconsin School of Medicine and Public Health. After his training, he has been on faculty at the University of Kentucky College of Medicine, leading its neuropsychology division. In 2012, Han and Frédéric Morin con ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Columbia University Press
Columbia University Press is a university press based in New York City New York, often called New York City (NYC), is the most populous city in the United States, located at the southern tip of New York State on one of the world's largest natural harbors. The city comprises five boroughs, each coextensive w ..., and affiliated with Columbia University. Founded in 1893, it is currently directed by Jennifer Crewe (2014–present) and publishes titles in the humanities and sciences, including the fields of literary and cultural studies, history, social work, sociology, religion, film, and international studies. History Columbia University Press was founded in May 1893. In 1933, the first four volumes of the ''History of the State of New York'' were published. In the early 1940s, the Press' revenues rose, partially thanks to the ''Encyclopedia'' and the government's purchase of 12,500 copies for use by the military. Columbia University Press is notable for publishing r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neurogastronomy
Neurogastronomy is the study of flavor perception and the ways it affects cognition and memory. This interdisciplinary field is influenced by the psychology and neuroscience of sensation, learning, satiety, and decision making. Areas of interest include how olfaction contributes to flavor, food addiction and obesity, taste preferences, and the linguistics of communicating and identifying flavor. The term neurogastronomy was coined by neuroscientist Gordon M. Shepherd. Olfaction and flavor Out of all the sensory modalities, olfaction contributes most to the sensation and perception of flavor processing. Olfaction has two sensory modalities, orthonasal smell, the detection of odor molecules originating outside the body, and retronasal smell, the detection of odor molecules originating during mastication. It is retronasal smell, whose sensation is felt in the mouth, that contributes to flavor perception. Anthropologically, over human evolution, the shortening of the nasopharynx ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oxford University Press
Oxford University Press (OUP) is the publishing house of the University of Oxford. It is the largest university press in the world. Its first book was printed in Oxford in 1478, with the Press officially granted the legal right to print books by decree in 1586. It is the second-oldest university press after Cambridge University Press, which was founded in 1534. It is a department of the University of Oxford. It is governed by a group of 15 academics, the Delegates of the Press, appointed by the Vice Chancellor, vice-chancellor of the University of Oxford. The Delegates of the Press are led by the Secretary to the Delegates, who serves as OUP's chief executive and as its major representative on other university bodies. Oxford University Press has had a similar governance structure since the 17th century. The press is located on Walton Street, Oxford, Walton Street, Oxford, opposite Somerville College, Oxford, Somerville College, in the inner suburb of Jericho, Oxford, Jericho. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neuron Doctrine
The neuron doctrine is the concept that the nervous system is made up of discrete individual cells, a discovery due to decisive neuro-anatomical work of Santiago Ramón y Cajal and later presented by, among others, H. Waldeyer-Hartz. The term ''neuron'' (spelled ''neurone'' in British English) was itself coined by Waldeyer as a way of identifying the cells in question. The ''neuron doctrine'', as it became known, served to position neurons as special cases under the broader cell theory evolved some decades earlier. He appropriated the concept not from his own research but from the disparate observation of the histological work of Albert von Kölliker, Camillo Golgi, Franz Nissl, Santiago Ramón y Cajal, Auguste Forel and others. Historical context Theodor Schwann proposed in 1839 that the tissues of all organisms are composed of cells. Schwann was expanding on the proposal of his good friend Matthias Jakob Schleiden the previous year that all plant tissues were composed ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Olfactory System
The olfactory system, is the sensory nervous system, sensory system used for the sense of smell (olfaction). Olfaction is one of the special senses directly associated with specific organs. Most mammals and reptiles have a main olfactory system and an accessory olfactory system. The main olfactory system detects airborne substances, while the accessory system senses fluid-phase stimuli. The senses of smell and taste (gustatory system) are often referred to together as the chemosensory system, because they both give the brain information about the chemical composition of objects through a process called transduction (physiology), transduction. Structure Peripheral The peripheral olfactory system consists mainly of the nostrils, ethmoid bone, nasal cavity, and the olfactory epithelium (layers of thin tissue covered in mucus that line the nasal cavity). The primary components of the layers of epithelial tissue are the mucous membranes, olfactory glands, olfactory receptor neurons ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Laboratory
A laboratory (; ; colloquially lab) is a facility that provides controlled conditions in which scientific or technological research, experiments, and measurement may be performed. Laboratories are found in a variety of settings such as schools, universities, privately owned research institutions, corporate research and testing facilities, government regulatory and forensic investigation centers, physicians' offices, clinics, hospitals, regional and national referral centers, and even occasionally personal residences. Overview The organisation and contents of laboratories are determined by the differing requirements of the specialists working within. A physics laboratory might contain a particle accelerator or vacuum chamber, while a metallurgy laboratory could have apparatus for casting or refining metals or for testing their strength. A chemist or biologist might use a wet laboratory, while a psychologist's laboratory might be a room with one-way mirrors and hidden ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Action Potential
An action potential (also known as a nerve impulse or "spike" when in a neuron) is a series of quick changes in voltage across a cell membrane. An action potential occurs when the membrane potential of a specific Cell (biology), cell rapidly rises and falls. This depolarization then causes adjacent locations to similarly depolarize. Action potentials occur in several types of Membrane potential#Cell excitability, excitable cells, which include animal cells like neurons and myocyte, muscle cells, as well as some plant cells. Certain endocrine cells such as pancreatic beta cells, and certain cells of the anterior pituitary gland are also excitable cells. In neurons, action potentials play a central role in cell–cell interaction, cell–cell communication by providing for—or with regard to saltatory conduction, assisting—the propagation of signals along the neuron's axon toward axon terminal, synaptic boutons situated at the ends of an axon; these signals can then connect wit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Glomerulus (olfaction)
The glomerulus (: glomeruli) is a spherical structure located in the olfactory bulb of the brain where synapses form between the terminals of the olfactory nerve and the dendrites of mitral, periglomerular and tufted cells. Each glomerulus is surrounded by a heterogeneous population of juxtaglomerular neurons (that include periglomerular, short axon, and external tufted cells) and glial cells. All glomeruli are located near the surface of the olfactory bulb. The olfactory bulb also includes a portion of the anterior olfactory nucleus, the cells of which contribute fibers to the olfactory tract. They are the initial sites for synaptic processing of odor information coming from the nose. A glomerulus is made up of a globular tangle of axons from the olfactory receptor neurons, and dendrites from the mitral and tufted cells, as well as, from cells that surround the glomerulus such as the external tufted cells, periglomerular cells, short axon cells, and astrocytes. In mammals, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
