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Glucuronate
Glucuronic acid (GCA, from ) is a uronic acid that was first isolated from urine (hence the name "uronic acid"). It is found in many gums such as gum arabic ( 18%), xanthan, and kombucha tea and is important for the metabolism of microorganisms, plants and animals. Properties Glucuronic acid is a sugar acid derived from glucose, with its sixth carbon atom oxidized to a carboxylic acid. In living beings, this primary oxidation occurs with UDP-α-D-glucose (UDPG), not with the free sugar. Glucuronic acid, like its precursor glucose, can exist as a linear (carboxo-)aldohexose (<1%), or as a cyclic ( or ) ...
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Uronic Acid
300px, The glucose.html" ;"title="Fischer projections of D-glucose">Fischer projections of D-glucose (left) and D-glucuronic acid (right). Glucose's terminal carbon's primary alcohol group has been oxidized to a carboxylic acid. Uronic acids () or alduronic acids are a class of sugar acids with both carbonyl and carboxylic acid functional groups. They are sugars in which the hydroxyl group furthest from the carbonyl group has been oxidized to a carboxylic acid. Usually the sugar is an aldose, but fructuronic acid also occurs. Oxidation of the terminal aldehyde instead yields an aldonic acid, while oxidation of both the terminal hydroxyl group and the aldehyde yields an aldaric acid. The names of uronic acids are generally based on their parent sugars, for example, the uronic acid analog of glucose is glucuronic acid. Uronic acids derived from hexoses are known as hexuronic acids and uronic acids derived from pentoses are known as penturonic acids. Examples Some of thes ...
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Xanthan
Xanthan gum () is a polysaccharide with many industrial uses, including as a common food additive. It is an effective thickening agent and stabilizer (food), stabilizer that prevents ingredients from separating. It can be produced from monosaccharide, simple sugars by fermentation and derives its name from the species of bacteria used, ''Xanthomonas campestris''. History Xanthan gum was discovered by Allene Jeanes, Allene Rosalind Jeanes and her research team at the United States Department of Agriculture and brought into commercial production by J.M. Huber Corporation, CP Kelco in the early 1960s under the trade name Kelzan, remaining the only manufacturer in the US. It was approved for use in foods in 1968 and is accepted as a safe food additive in the US, Canada, European countries, and many other countries, with E number E415 and CAS Registry Number, CAS number 11138-66-2. Xanthan gum derives its name from the species of bacteria used during the fermentation process, ''Xantho ...
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Sigma-Aldrich
Sigma-Aldrich (formally MilliporeSigma) is an American chemical, life science, and biotechnology company owned by the multinational chemical conglomerate Merck Group. Sigma-Aldrich was created in 1975 by the merger of Sigma Chemical Company and Aldrich Chemical Company. It grew through various acquisitions until it had over 9,600 employees and was listed on the Fortune 1000. The company has two United States headquarters, in St. Louis and Burlington, MA and has operations in approximately 40 countries. In 2015, the multinational chemical conglomerate Merck Group acquired Sigma-Aldrich for $17 billion. The company is currently a part of Merck's life science business and in combination with Merck's earlier acquired Millipore Corporation, Millipore, operates as MilliporeSigma. It is headquartered in Burlington, Massachusetts, United States. History Sigma Chemical Company of St. Louis and Aldrich Chemical Company of Milwaukee were both American specialty chemical companies when they ...
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Hemiacetal
In organic chemistry, a hemiacetal is a functional group the general formula , where is a hydrogen atom or an organic substituent. They generally result from the nucleophilic Addition reaction, addition of an Alcohol (chemistry), alcohol (a compound with at least one hydroxy group) to an aldehyde () or a ketone () under acidic conditions. The addition of an alcohol to a ketone is more commonly referred to as a hemiketal. Common examples of hemiacetals include cyclic Monosaccharide, monosaccharides. Hemiacetals have use as a protecting group and in synthesizing oxygenated heterocycles like Tetrahydrofuran, tetrahydrofurans. Nomenclature According to the IUPAC definition of a hemiacetal, the R1 and R2 groups may or may not be hydrogen. In a hemiketal, both of these R-groups must not be hydrogen. Thus, hemiketals are regarded as a subclass of hemiacetals. The prefix ''hemi,'' meaning half, refers to the one alcohol added to the carbonyl group. This is half of the required alcohols to ...
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Aldohexose
In chemistry, a hexose is a monosaccharide (simple sugar) with six carbon atoms. The chemical formula for all hexoses is , and their molecular weight is 180.156 g/mol. Hexoses exist in two forms, open-chain or cyclic, that easily convert into each other in aqueous solutions. The open-chain form of a hexose, which usually is favored in solutions, has the general structure , where ''n'' is 1, 2, 3, 4, 5. Namely, five of the carbons have one hydroxyl functional group () each, connected by a single bond, and one has an oxo group (), forming a carbonyl group (). The remaining bonds of the carbon atoms are satisfied by seven hydrogen atoms. The carbons are commonly numbered 1 to 6 starting at the end closest to the carbonyl. Hexoses are extremely important in biochemistry, both as isolated molecules (such as glucose and fructose) and as building blocks of other compounds such as starch, cellulose, and glycosides. Hexoses can form dihexose (like sucrose) by a condensation reacti ...
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Uridine Diphosphate Glucose
Uridine diphosphate glucose (uracil-diphosphate glucose, UDP-glucose) is a nucleotide sugar. It is involved in glycosyltransferase reactions in metabolism. Functions UDP-glucose is used in nucleotide sugar metabolism as an activated form of glucose, a substrate for enzymes called glucosyltransferases. UDP-glucose is a precursor of glycogen and can be converted into UDP-galactose and UDP-glucuronic acid, which can then be used as substrates by the enzymes that make polysaccharides containing galactose and glucuronic acid. UDP-glucose can also be used as a precursor of sucrose, lipopolysaccharides and glycosphingolipids. Components UDP-glucose consists of the pyrophosphate group, ribose, glucose, and uracil. See also * DNA * Nucleoside * Nucleotide * Oligonucleotide * RNA * TDP-glucose * Uracil * Uridine diphosphate Uridine diphosphate, abbreviated UDP, is an organic compound. It is an ester of pyrophosphoric acid with the nucleoside uridine. UDP consists of the pyrop ...
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Glucose
Glucose is a sugar with the Chemical formula#Molecular formula, molecular formula , which is often abbreviated as Glc. It is overall the most abundant monosaccharide, a subcategory of carbohydrates. It is mainly made by plants and most algae during photosynthesis from water and carbon dioxide, using energy from sunlight. It is used by plants to make cellulose, the most abundant carbohydrate in the world, for use in cell walls, and by all living Organism, organisms to make adenosine triphosphate (ATP), which is used by the cell as energy. In energy metabolism, glucose is the most important source of energy in all organisms. Glucose for metabolism is stored as a polymer, in plants mainly as amylose and amylopectin, and in animals as glycogen. Glucose circulates in the blood of animals as blood sugar. The naturally occurring form is -glucose, while its Stereoisomerism, stereoisomer L-glucose, -glucose is produced synthetically in comparatively small amounts and is less biologicall ...
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Sugar Acid
In organic chemistry, a sugar acid or acidic sugar is a monosaccharide with a carboxyl group at one end or both ends of its Polymer backbone, chain. Main classes of sugar acids include: * Aldonic acids, in which the aldehyde group () located at the initial end (Monosaccharide#Linear-chain monosaccharides, position 1) of an aldose is oxidized. * Ulosonic acids, in which the hydroxymethyl group () at the initial end of a 2-ketose is oxidized creating an α-ketoacid. * Uronic acids, in which the group at the terminal end of an aldose or ketose is oxidized. * Aldaric acids, in which both ends ( and ) of an aldose are oxidized. Examples Examples of sugar acids include: * Aldonic acids ** Glyceric acid (3C) ** Xylonic acid (5C) ** Gluconic acid (6C) ** Ascorbic acid (6C, unsaturated lactone) * Ulosonic acids ** Neuraminic acid (5-amino-3,5-dideoxy-D-glyceraldehyde, ''glycero''-D-galactose, ''galacto''-non-2-ulosonic acid) ** Ketodeoxyoctulosonic acid (KDO or 3-deoxy-D-mannose, ''mann ...
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GlcA
The Great Lakes Colleges Association (GLCA) is a consortium of 13 liberal arts colleges located in the states around the Great Lakes. The GLCA's offices are located in Ann Arbor, Michigan and its 13 schools are located in Michigan, Ohio, Pennsylvania and Indiana. It was chartered in the state of Michigan and incorporated as a 501(c)(3) non-profit organization in 1962. Its stated mission is to take actions that will help strengthen and preserve its colleges, being a leading force on behalf of education in the tradition of the liberal arts and sciences. The organization is the founder and administrator of the Global Liberal Arts Alliance. Operations GLCA operates a Tuition Remission Exchange involving its 13 colleges plus Beloit College, Grinnell College, Willamette University, and Wittenberg University, by which students eligible for tuition remission because of parental employment at one of the colleges will receive tuition remission at any one of the other colleges in the Excha ...
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Metabolism
Metabolism (, from ''metabolē'', "change") is the set of life-sustaining chemical reactions in organisms. The three main functions of metabolism are: the conversion of the energy in food to energy available to run cellular processes; the conversion of food to building blocks of proteins, lipids, nucleic acids, and some carbohydrates; and the elimination of metabolic wastes. These enzyme-catalyzed reactions allow organisms to grow and reproduce, maintain their Structures#Biological, structures, and respond to their environments. The word ''metabolism'' can also refer to the sum of all chemical reactions that occur in living organisms, including digestion and the transportation of substances into and between different cells, in which case the above described set of reactions within the cells is called intermediary (or intermediate) metabolism. Metabolic reactions may be categorized as ''catabolic''—the ''breaking down'' of compounds (for example, of glucose to pyruvate by c ...
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Kombucha
Kombucha (also tea mushroom, tea fungus, or Manchurian mushroom when referring to the Microbiological culture, culture; Latin name ''Medusomyces gisevii'') is a fermented beverage, fermented, effervescent, Sweetened beverage, sweetened black tea drink. Sometimes the beverage is called kombucha tea to distinguish it from the culture of bacteria and yeast. Juice, spices, fruit, or other flavorings are often added. Commercial kombucha contains minimal amounts of Alcohol (drug), alcohol. Kombucha is named after the Japanese language, Japanese term for Kelp tea, seaweed tea thought to have originated in China, where the drink is traditional. By the early 20th century it spread to Russia, then other parts of Eastern Europe and Germany. Kombucha is now Homebrewing, homebrewed globally, and also bottled and sold commercially. The global kombucha market was worth approximately billion . Kombucha is produced by symbiotic fermentation of sugared tea using a symbiotic culture of bacteri ...
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