Giant Virus
A giant virus, sometimes referred to as a girus, is a very large virus, some of which are larger than typical bacteria. All known giant viruses belong to the phylum ''Nucleocytoviricota''. Description While the exact criteria as defined in the scientific literature vary, giant viruses are generally described as viruses having large, pseudo-Capsid#Icosahedral, icosahedral capsids (200 to 400 nanometers in diameter) that may be surrounded by a thick (approximately 100 nm) layer of filamentous protein fibers. The viruses have large, double-stranded DNA genomes (300 to >1000 kilobasepairs) that encode a large contingent of genes (of the order of 1000 genes). The best characterized giant viruses are the phylogenetically related mimivirus and megavirus, which belong to the family ''Mimiviridae'' (aka ''Megaviridae''), and are distinguished by their large capsid diameters. Giant viruses from the deep ocean, terrestrial sources, and human patients contain genes encoding Cytochrome P4 ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Virus
A virus is a submicroscopic infectious agent that replicates only inside the living Cell (biology), cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Viruses are found in almost every ecosystem on Earth and are the most numerous type of biological entity. Since Dmitri Ivanovsky's 1892 article describing a non-bacterial pathogen infecting tobacco plants and the discovery of the tobacco mosaic virus by Martinus Beijerinck in 1898, more than 16,000 of the millions of List of virus species, virus species have been described in detail. The study of viruses is known as virology, a subspeciality of microbiology. When infected, a host cell is often forced to rapidly produce thousands of copies of the original virus. When not inside an infected cell or in the process of infecting a cell, viruses exist in the form of independent viral particles, or ''virions'', consisting of (i) genetic material, i.e., long ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Esterification
In chemistry, an ester is a compound derived from an acid (either organic or inorganic) in which the hydrogen atom (H) of at least one acidic hydroxyl group () of that acid is replaced by an organyl group (R). These compounds contain a distinctive functional group. Analogues derived from oxygen replaced by other chalcogens belong to the ester category as well. According to some authors, organyl derivatives of acidic hydrogen of other acids are esters as well (e.g. amides), but not according to the IUPAC. Glycerides are fatty acid esters of glycerol; they are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils. Lactones are cyclic carboxylic esters; naturally occurring lactones are mainly 5- and 6-membered ring lactones. Lactones contribute to the aroma of fruits, butter, cheese, vegetables like celery and other foods. Esters can be formed from oxoacids (e.g. esters of acetic acid, carbonic acid, sulfu ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Klosneuvirus
''Klosneuvirus'' (KNV, also KloV) is a new type of giant virus found by the analysis of low-complexity metagenomes from a wastewater treatment plant in Klosterneuburg, Austria. It has a 1.57-Mb genome coding unusually high number of genes typically found in cellular organisms, including aminoacyl transfer RNA synthetases with specificities for 19 different amino acids, over 10 translation factors and several tRNA-modifying enzymes. ''Klosneuvirus'', '' Indivirus'', '' Catovirus'' and '' Hokovirus'', are part of a group of giant viruses denoted as Klosneuviruses or '' Klosneuvirinae'', a proposed subfamily of the ''Mimiviridae''. Species in this clade include ''Bodo saltans virus'' infecting the kinetoplastid ''Bodo saltans''. Phylogenetic tree topology of ''Mimiviridae'' is still under discussion. As Klosneuviruses are related to ''Mimivirus'', it was proposed to put them all together into a subfamily ''Megavirinae''. Other authors (CNS 2018) like to put Klosneuviruses just ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Giant Virus Finder
The Giant Virus Finder is a free bioinformatics software for finding giant viruses in metagenomes. Applications The Giant Virus Finder tool integrates and applies thGiant Virus Toplist the list of the largest virus genomes. With the tool, giant viruses were found in diverse habitats, like the Great Rann of Kutch or the Mojave Desert, the Prairie Prairies are ecosystems considered part of the temperate grasslands, savannas, and shrublands biome by ecologists, based on similar temperate climates, moderate rainfall, and a composition of grasses, herbs, and shrubs, rather than trees, as the ..., or the Antarctic dry valleys. References {{reflist Metagenomics software Free bioinformatics software ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Mimivirus
''Mimivirus'' is a genus of giant viruses, in the family ''Mimiviridae''. It is believed that Amoeba serve as their natural hosts. It also refers to a group of phylogenetically related large viruses. In colloquial speech, APMV is more commonly referred to as just "mimivirus". Mimivirus, short for "mimicking microbe", is so called to reflect its large size and apparent Gram-staining properties. Mimivirus has a large and complex genome compared with most other viruses. Until 2013, when a larger virus ''Pandoravirus'' was described, it had the largest capsid diameter of all known viruses. History APMV was discovered accidentally in 1992 within the amoeba ''Acanthamoeba, Acanthamoeba polyphaga'', after which it is named, during research into legionellosis by researchers from Marseille and Leeds. The virus was observed in a Gram stain and mistakenly thought to be a Gram-positive bacterium. As a consequence it was named ''Bradfordcoccus'', after Bradford, England, where the amoeba h ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Mamavirus
Mamavirus is a large and complex virus in the Group I family ''Mimiviridae''. The virus is exceptionally large, and larger than many bacteria. Mamavirus and other mimiviridae belong to nucleocytoplasmic large DNA virus (NCLDVs) family. Mamavirus can be compared to the similar complex virus mimivirus; mamavirus was so named because it is similar to but larger than mimivirus. Discovery Mamavirus was first reported in September 2008. Like mimivirus, mamavirus was isolated from an amoeba in a cooling tower. The mimiviridae were not discovered until recently because of their size; when filtered the mimiviridae stay with the bacteria which led scientists to believe they were also bacteria. Mimivirus was first isolated in 1992 when scientists were looking for the cause of a pneumonia outbreak in Bradford, UK. Due to its size it was named ''Bradfordcoccus'' and put in a freezer with scientists thinking it was a bacterium. A decade later, Jean-Michel Claverie and Didier Raoult discovered ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Megavirus Chilense
''Megavirus'' is a viral genus, phylogenetically related to '' Acanthamoeba polyphaga mimivirus'' (APMV). In colloquial speech, ''Megavirus chilense'' is more commonly referred to as just "Megavirus". Until the discovery of pandoraviruses in 2013, it had the largest capsid diameter of all known viruses, as well as the largest and most complex genome among all known viruses. Discovery ''Megavirus'' was isolated from a water sample collected in April 2010 off the coast of Chile, near the marine station in Las Cruces, by Jean-Michel Claverie and Chantal Abergel from the Structural & Genomic Information laboratory (IGS, CNRS and Aix-Marseille University). Megavirus was isolated by co-cultivation with a variety of ''Acanthamoeba'' laboratory strains ('' Acanthamoeba polyphaga'', '' Acanthamoeba castellanii'', '' Acanthamoeba griffini'') following a protocol pioneered by Timothy Rowbotham for isolating intracellular parasitic bacteria. Megavirus infects amoebas. Structure The Me ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Bodo Saltans Virus
The Bodo saltans virus is a giant virus of the ''Mimiviridae'' family that infects the protozoa ''Bodo saltans''. It has a genome A genome is all the genetic information of an organism. It consists of nucleotide sequences of DNA (or RNA in RNA viruses). The nuclear genome includes protein-coding genes and non-coding genes, other functional regions of the genome such as ... of 1.39 megabases, one of the largest known viral genomes. References Mimiviridae {{Virus-stub ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Tupanvirus
''Tupanvirus'' is a genus of viruses first described in 2018. The genus is composed of two species of virus that are in the giant virus group. Researchers discovered the first isolate in 2012 from deep water sediment samples taken at 3,000 m depth off the coast of Brazil. The second isolate was collected from a soda lake in Southern Nhecolândia, Brazil in 2014. They are named after Tupã (Tupan), a Guaraní thunder god, and the places they were found. These are the first viruses reported to possess genes for amino-acyl tRNA synthetases for all 20 standard amino acids. Classification The genus ''Tupanvirus'' was first described in 2018 with the discovery of the two isolates of tupanviruses found in soda lake and deep oceanic sediment samples collected in Brazil. The genus is currently unassigned but hypothesized to be a member of the family ''Mimiviridae'', along with the other amoeba-infecting viruses. Members of the family ''Mimiviridae'' include ''Acanthamoeba polyphaga ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Pandoravirus Salinus
''Pandoravirus salinus'' is a large virus of genus ''Pandoravirus'', found in the marine sediment layer of the Tunquen River in Chile, and is one of the largest viruses identified, along with '' Pandoravirus dulcis''. It is 2.5 million nucleobases long, encodes for about 2,500 genes, and is visible through an optical microscope The optical microscope, also referred to as a light microscope, is a type of microscope that commonly uses visible light and a system of lenses to generate magnified images of small objects. Optical microscopes are the oldest design of micros .... It was first identified in 2013. References 2013 in science Nucleocytoplasmic large DNA viruses Unaccepted virus taxa {{Virus-stub ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Three-domain System
The three-domain system is a taxonomic classification system that groups all cellular life into three domains, namely Archaea, Bacteria and Eukarya, introduced by Carl Woese, Otto Kandler and Mark Wheelis in 1990. The key difference from earlier classifications such as the two-empire system and the five-kingdom classification is the splitting of Archaea (previously named "archaebacteria") from Bacteria as completely different organisms. The three domain hypothesis is considered obsolete by some since it is thought that eukaryotes do not form a separate domain of life; instead, they arose from a fusion between two different species, one from within Archaea and one from within Bacteria. (see Two-domain system) Background Woese argued, on the basis of differences in 16S rRNA genes, that bacteria, archaea, and eukaryotes each arose separately from an ancestor with poorly developed genetic machinery, often called a progenote. To reflect these primary lines of descent, he tr ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Genome Size
Genome size is the total amount of DNA contained within one copy of a single complete genome. It is typically measured in terms of mass in picograms (trillionths or 10−12 of a gram, abbreviated pg) or less frequently in daltons, or as the total number of nucleotide base pairs, usually in megabases (millions of base pairs, abbreviated Mb or Mbp). One picogram is equal to 978 megabases. In diploid organisms, genome size is often used interchangeably with the term C-value. An organism's complexity is not directly proportional to its genome size; total DNA content is widely variable between biological taxa. Some single-celled organisms have much more DNA than humans, for reasons that remain unclear (see Junk DNA and C-value). Variation in genome size and gene content Since the 1950s, with the emergence of various molecular techniques, the genome sizes of thousands of eukaryotes have been analyzed, and these data are available in online databases for animals, plants, and fung ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |