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Gedunin
Gedunin is a pentacyclic triterpenoid with the molecular formula C28H34 O7. It is most notably found in Azadirachta indica, but is a constituent of several other plants. Gedunin shows therapeutic potential in the treatment of leukemia, and Parkinson's disease. Natural occurrence Azadirachta indica is the most notable source of gedunin, but it has also been found in the following plants: * Cedrela fissilis * Cedrela odorata * Cedrela salvadorensis * Entandrophragma angolense * Khaya grandifoliola * Melia azedarach * Toona sinensis * Xylocarpus granatum ''Xylocarpus granatum'', commonly known as the cannonball mangrove, cedar mangrove, or puzzlenut tree, is a species of mangrove in the mahogany family (Meliaceae). It is found in Africa, Asia, Australasia and the Pacific Islands. It is a common ... References Acetate esters Antimalarial agents Antineoplastic and immunomodulating drugs Antineoplastic drugs Enones Epoxides 3-Furyl compounds Lactones Heterocyclic c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pentacyclic Compound
In the field of organic chemistry, a polycyclic compound is an organic compound featuring several closed rings of atoms, primarily carbon. These ring substructures include cycloalkanes, aromatics, and other ring types. They come in sizes of three atoms and upward, and in combinations of linkages that include tethering (such as in biaryls), fusing (edge-to-edge, such as in anthracene and steroids), links via a single atom (such as in spiro compounds), bridged compounds, and longifolene. Though poly- literally means "many", there is some latitude in determining how many rings are required to be considered polycyclic; many smaller rings are described by specific prefixes (e.g., bicyclic, tricyclic, tetracyclic, etc.), and so while it can refer to these, the title term is used with most specificity when these alternative names and prefixes are unavailable. In general, the term polycyclic includes polycyclic aromatic compounds, including polycyclic aromatic hydrocarbons, as well a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Toona Sinensis
''Toona sinensis'', common name, commonly called Chinese mahogany, Chinese cedar, Chinese toon, beef and onion plant, or red toon (; ; ; ; ) is a species of ''Toona'' native to eastern and southeastern Asia, ranging from northern Korean peninsula through most of eastern, central, and southwestern China, in Nepal, northeastern India, Burma (Myanmar), Thailand, and even present in Malaysia and western Indonesia.University of MelbourneSorting ''Toona'' names/ref>Hong Kong trees(in Chinese, with photosRushforth, K. (1999). ''Trees of Britain and Europe''. Collins . Characteristics It is a deciduous tree growing to tall with a trunk up to 70 cm diameter. The Bark (botany), bark is brown, smooth on young trees, becoming scaly to shaggy on old trees. The leaf, leaves are pinnate, 50–70 cm long and 30–40 cm broad, with 10–40 leaflets, the terminal leaflet usually absent (paripinnate) but sometimes present (imparipennate); the individual leaflets 9–15 cm long a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lactones
Lactones are cyclic carboxylic esters. They are derived from the corresponding hydroxycarboxylic acids by esterification. They can be saturated or unsaturated. Lactones are formed by lactonization, the intramolecular esterification of the corresponding hydroxycarboxylic acids. Nomenclature Greek prefixes in alphabetical order indicate ring size. Lactones are usually named according to the precursor acid molecule (''aceto'' = 2 carbon atoms, ''propio'' = 3, ''butyro'' = 4, ''valero'' = 5, ''capro'' = 6, etc.), with a ''-lactone'' suffix and a Greek letter prefix that specifies the number of carbon atoms in the heterocycle — that is, the distance between the relevant -OH and the -COOH groups along said backbone. The first carbon atom after the carbon in the -COOH group on the parent compound is labelled α, the second will be labeled β, and so forth. Therefore, the prefixes also indicate the size of the lactone ring: α-lactone = 3-membered ring, β-lactone = 4-membered, γ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Epoxides
In organic chemistry, an epoxide is a cyclic ether, where the ether forms a three-atom Ring (chemistry), ring: two atoms of carbon and one atom of oxygen. This triangular structure has substantial ring strain, making epoxides highly Reactivity (chemistry), reactive, more so than other ethers. They are produced on a large scale for many applications. In general, low molecular weight epoxides are colourless and nonpolar, and often Volatility (chemistry), volatile. Nomenclature A compound containing the epoxide functional group can be called an epoxy, epoxide, oxirane, and ethoxyline. Simple epoxides are often referred to as oxides. Thus, the epoxide of ethylene (C2H4) is ethylene oxide (C2H4O). Many compounds have trivial names; for instance, ethylene oxide is called "oxirane". Some names emphasize the presence of the epoxide functional group, as in the compound ''1,2-epoxyheptane'', which can also be called ''1,2-heptene oxide''. A polymer formed from epoxide precursors is c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antineoplastic Drugs
Chemotherapy (often abbreviated chemo, sometimes CTX and CTx) is the type of cancer treatment that uses one or more anti-cancer drugs ( chemotherapeutic agents or alkylating agents) in a standard regimen A regimen is a plan, or course of action such as a Diet (nutrition), diet, exercise or medical treatment. A salt#Health effects, low-salt diet is a regimen. A course of penicillin is a regimen, and there are many chemotherapy regimens in the trea .... Chemotherapy may be given with a curative intent (which almost always involves combinations of drugs), or it may aim only to prolong life or to Palliative care, reduce symptoms (Palliative care, palliative chemotherapy). Chemotherapy is one of the major categories of the medical discipline specifically devoted to pharmacotherapy for cancer, which is called ''oncology#Specialties, medical oncology''. The term ''chemotherapy'' now means the non-specific use of intracellular poisons to inhibit mitosis (cell division) or to indu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antimalarial Agents
Antimalarial medications or simply antimalarials are a type of antiparasitic chemical agent, often natural product, naturally derived, that can be used to treat or to prevent malaria, in the latter case, most often aiming at two susceptible target groups, young children and pregnant women. As of 2018, modern treatments, including for severe malaria, continued to depend on therapies deriving historically from quinine and artesunate, both parenteral (injectable) drugs, expanding from there into the many classes of available modern drugs. Incidence and distribution of the disease ("malaria burden") is expected to remain high, globally, for many years to come; moreover, known antimalarial drugs have repeatedly been observed to elicit resistance in the malaria parasite—including for combination therapies featuring artemisinin, a drug of last resort, where resistance has now been observed in Southeast Asia. As such, the needs for new antimalarial agents and new strategies of treatment ( ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Acetate Esters
An acetate is a salt formed by the combination of acetic acid with a base (e.g. alkaline, earthy, metallic, nonmetallic, or radical base). "Acetate" also describes the conjugate base or ion (specifically, the negatively charged ion called an anion) typically found in aqueous solution and written with the chemical formula . The neutral molecules formed by the combination of the acetate ion and a ''positive'' ion (called a cation) are also commonly called "acetates" (hence, ''acetate of lead'', ''acetate of aluminium'', etc.). The simplest of these is hydrogen acetate (called acetic acid) with corresponding salts, esters, and the polyatomic anion , or . Most of the approximately 5 million tonnes of acetic acid produced annually in industry are used in the production of acetates, which usually take the form of polymers. In nature, acetate is the most common building block for biosynthesis. Nomenclature and common formula When part of a salt, the formula of the acetate ion is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Xylocarpus Granatum
''Xylocarpus granatum'', commonly known as the cannonball mangrove, cedar mangrove, or puzzlenut tree, is a species of mangrove in the mahogany family (Meliaceae). It is found in Africa, Asia, Australasia and the Pacific Islands. It is a common species of mangrove, and the International Union for Conservation of Nature has assessed its conservation status as being of "least concern". Description ''Xylocarpus granatum'' is a small to medium-sized evergreen tree, growing to a maximum height of . The trunk has buttresses and above-ground roots which extend for long distances to either side. The bark is brown and smooth, and comes away in flakes. The leaves are pinnate and arranged spirally on the twigs; they have two to four pairs of leaflets and are pale green when young and darken with age. The inflorescence grows in a short panicle in the axil of a leaf or at the end of the shoot. The individual flowers are wide, with parts in fours, and are white or pinkish-yellow. They are fo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Melia Azedarach
''Melia azedarach'', commonly known as the chinaberry tree, pride of India, bead-tree, Cape lilac, syringa berrytree, Persian lilac, Indian lilac, or white cedar, is a species of deciduous tree in the mahogany family (biology), family, Meliaceae, that is native to Indomalayan realm, Indomalaya and Australasian realm, Australasia. Description The fully grown tree has a rounded crown, and commonly measures tall, exceptionally . The leaves are up to long, alternate, long-petioled, two or three times compound (odd-pinnate); the leaflet (botany), leaflets are dark green above and lighter green below, with serrate margins. The flowers are small and fragrant, with five pale purple or lilac petals, growing in clusters. The fruit is a drupe, marble-sized, light yellow at maturity, hanging on the tree all winter, and gradually becoming wrinkled and almost white. ''Melia azedarach'' has a short lifespan, averaging about 20 years. Chemistry Italo et al. 2009 and Safithri and Sa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
