Félix Mesnil
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Félix Mesnil
Félix Étienne Pierre Mesnil ( Omonville-la-Petite, La Manche department, 12 December 1868 – 15 February 1938, Paris) was a French zoologist, biologist, botanist, mycologist and algologist. He was a student of Alfred Giard at the École Normale Supérieure and a classmate of Maurice Caullery. From 1892 he worked at the Pasteur Institute, initially as an associate demonstrator. He was an assistant of Louis Pasteur, and in the meantime, performed studies on cellular immunity, physiology and comparative pathology in the laboratory of Ilya Ilyich Metchnikov (1845–1916). He founded the ''Pasteur Institute Bulletin'' with Gabriel Bertrand (1867–1962), Alexandre Besredka (1870–1940), Amédée Borrel (1867–1936), Camille Delezenne (1868–1932) and Auguste-Charles Marie (1864–1935). As a member of the French Commission on sleeping sickness, he worked for the organisation of the mission in French Equatorial Africa. He also worked for the creation of the Société de ...
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Alexandre Besredka
Alexandre Mikhailovich Besredka (29 March 1870 – 28 February 1940) was a Ukrainian-French biologist and immunologist born in Odessa. In 1910 he became a citizen of France. He studied biology in Odessa (1888–92), afterwards moving to Paris, where he was an assistant to Ilya Ilyich Metchnikov (1845–1916) at the Pasteur Institute. He obtained his medical degree in 1897 with the thesis ''Abscès sous-phréniques''. In 1903 with Amédée Borrel (1867–1936), Félix Mesnil (1868–1938), Gabriel Bertrand (1867–1962), Camille Delezenne (1868–1932) and Auguste-Charles Marie (1864–1935), he co-founded the ''Bulletin de l'Institut Pasteur''. From 1905 to 1914 he was in charge of the laboratory at the Pasteur Institute.Alexandre Mikhailovich Besredka
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Plasmodium
''Plasmodium'' is a genus of unicellular eukaryotes that are obligate parasites of vertebrates and insects. The life cycles of ''Plasmodium'' species involve development in a Hematophagy, blood-feeding insect host (biology), host which then injects parasites into a vertebrate host during a blood meal. Parasites grow within a vertebrate body tissue (often the liver) before entering the bloodstream to infect red blood cells. The ensuing destruction of host red blood cells can result in malaria. During this infection, some parasites are picked up by a blood-feeding insect (mosquitoes in majority cases), continuing the life cycle. ''Plasmodium'' is a member of the phylum Apicomplexa, a large group of parasitic eukaryotes. Within Apicomplexa, ''Plasmodium'' is in the order Haemosporida and family Plasmodiidae. Over 200 species of ''Plasmodium'' have been described, many of which have been subdivided into 14 subgenera based on parasite morphology and host range. Evolutionary relations ...
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Trypanosoma
''Trypanosoma'' is a genus of kinetoplastids (class Trypanosomatidae), a monophyletic group of unicellular parasitic flagellate protozoa. Trypanosoma is part of the phylum Euglenozoa. The name is derived from the Ancient Greek ''trypano-'' (borer) and ''soma'' (body) because of their corkscrew-like motion. Most trypanosomes are heteroxenous (requiring more than one obligatory host to complete life cycle) and most are transmitted via a vector. The majority of species are transmitted by blood-feeding invertebrates, but there are different mechanisms among the varying species. '' Trypanosoma equiperdum'' is spread between horses and other equine species by sexual contact. They are generally found in the intestine of their invertebrate host, but normally occupy the bloodstream or an intracellular environment in the vertebrate host. Trypanosomes infect a variety of hosts and cause various diseases, including the fatal human diseases sleeping sickness, caused by '' Trypanosoma br ...
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Protozoa
Protozoa (: protozoan or protozoon; alternative plural: protozoans) are a polyphyletic group of single-celled eukaryotes, either free-living or parasitic, that feed on organic matter such as other microorganisms or organic debris. Historically, protozoans were regarded as "one-celled animals". When first introduced by Georg Goldfuss, in 1818, the taxon Protozoa was erected as a class within the Animalia, with the word 'protozoa' meaning "first animals", because they often possess animal-like behaviours, such as motility and predation, and lack a cell wall, as found in plants and many algae. This classification remained widespread in the 19th and early 20th century, and even became elevated to a variety of higher ranks, including phylum, subkingdom, kingdom, and then sometimes included within the paraphyletic Protoctista or Protista. By the 1970s, it became usual to require that all taxa be monophyletic (derived from a common ancestor that would also be regarded as protozo ...
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William Boog Leishman
Lieutenant-General Sir William Boog Leishman, ( ; 6 November 1865 – 2 June 1926) was a Scottish pathologist and British Army medical officer. He was Director-General of Army Medical Services from 1923 to 1926. Biography Leishman was born in Glasgow and attended Westminster School and the University of Glasgow and entered the Royal Army Medical Corps. He served in India, where he did research on enteric fever and kala-azar. He returned to the United Kingdom and was stationed at the Victoria Hospital in Netley in 1897. In 1900 he was made Assistant Professor of Pathology in the Army Medical School, and described a method of staining blood for malaria and other parasites—a modification and simplification of the existing Romanowsky method using a compound of methylene blue and eosin, which became known as Leishman's stain. In 1901, while examining pathologic specimens of a spleen from a patient who had died of kala azar (now called "visceral leishmaniasis"), he observed ov ...
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Visceral Leishmaniasis
Visceral leishmaniasis (VL), also known as kala-azar (Hindi: kālā āzār, "black sickness") or "black fever", is the most severe form of leishmaniasis and, without proper diagnosis and treatment, is associated with high fatality. Leishmaniasis is a disease caused by protozoan parasites of the genus ''Leishmania''. The parasite migrates to the internal organs such as the liver, spleen (hence "visceral"), and bone marrow, and, if left untreated, will almost always result in the death of the host. Signs and symptoms include fever, weight loss, fatigue, anemia, and substantial swelling of the liver and spleen. Of particular concern, according to the World Health Organization (WHO), is the emerging problem of HIV/VL co-infection. VL is the second-largest parasitic killer in the world (after malaria), responsible for an estimated 20,000 to 30,000 deaths each year worldwide. Upendranath Brahmachari synthesised urea stibamine (carbostibamide) in 1922 and determined that it was an ...
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Parasite
Parasitism is a Symbiosis, close relationship between species, where one organism, the parasite, lives (at least some of the time) on or inside another organism, the Host (biology), host, causing it some harm, and is Adaptation, adapted structurally to this way of life. The entomologist E. O. Wilson characterised parasites' way of feeding as "predators that eat prey in units of less than one". Parasites include single-celled protozoans such as the agents of malaria, sleeping sickness, and amoebic dysentery; animals such as hookworms, lice, mosquitoes, and vampire bats; fungi such as Armillaria mellea, honey fungus and the agents of ringworm; and plants such as mistletoe, dodder, and the Orobanchaceae, broomrapes. There are six major parasitic Behavioral ecology#Evolutionarily stable strategy, strategies of exploitation of animal hosts, namely parasitic castration, directly transmitted parasitism (by contact), wikt:trophic, trophicallytransmitted parasitism (by being eaten), ...
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Alphonse Laveran
Charles Louis Alphonse Laveran (18 June 1845 – 18 May 1922) was a French physician who won the Nobel Prize in Physiology or Medicine in 1907 for his discoveries of parasitic protozoans as causative agents of infectious diseases such as malaria and trypanosomiasis. Following his father, Louis Théodore Laveran, he took up military medicine as his profession. He obtained his medical degree from University of Strasbourg in 1867. At the outbreak of the Franco-Prussian War in 1870, he joined the French Army. At the age of 29 he became Chair of Military Diseases and Epidemics at the Val-de-Grâce, École de Val-de-Grâce. At the end of his tenure in 1878 he worked in Algeria, where he made his major achievements. He discovered that the protozoan parasite ''Plasmodium'' was responsible for malaria, and that ''Trypanosoma'' caused trypanosomiasis or African sleeping sickness. In 1894 he returned to France to serve in various military health services. In 1896 he joined Pasteur Institute ...
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Société De Pathologie Exotique
Groupe Lactalis S.A. (doing business as Lactalis) is a French multinational dairy products corporation, owned by the Besnier family and based in Laval, Mayenne, France. The company's former name was Besnier S.A. Lactalis is the largest dairy products group in the world, and is the second largest food products group in France, behind Danone. It owns brands such as Parmalat, Président, Kraft Natural Cheese, Siggi's Dairy, Skånemejerier, Rachel's Organic, and Stonyfield Farm. History André Besnier started a small cheesemaking company in 1933 and launched its '' Président'' brand of Camembert in 1968. In 1990, it acquired Group Bridel (2,300 employees, 10 factories, fourth-largest French dairy group) with a presence in 60 countries. In 1992, it acquired United States cheese company Sorrento. In 1999, ''la société Besnier'' became ''le groupe Lactalis'' owned by Belgian holding company BSA International SA. In 2006, they bought Italian group Galbani, and in 2008, bought Swis ...
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French Equatorial Africa
French Equatorial Africa (, or AEF) was a federation of French colonial territories in Equatorial Africa which consisted of Gabon, French Congo, Ubangi-Shari, and Chad. It existed from 1910 to 1958 and its administration was based in Brazzaville. History Established in 1910, the Federation contained four colonial possessions: French Gabon, French Congo, Ubangi-Shari and French Chad. The Governor-General was based in Brazzaville with deputies in each territory. In 1911, France ceded parts of the territory to German Kamerun as a result of the Agadir Crisis. The territory was returned after Germany's defeat in World War I, while most of French Cameroon, Cameroon proper became a French League of Nations mandate not integrated into the AEF. French Equatorial Africa, especially the region of Ubangi-Shari, had a similar concession system as the Congo Free State and similar atrocities were also committed there. Writer André Gide traveled to Ubangi-Shari and was told by inhabita ...
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African Trypanosomiasis
African trypanosomiasis is an insect-borne parasitic infection of humans and other animals. Human African trypanosomiasis (HAT), also known as African sleeping sickness or simply sleeping sickness, is caused by the species ''Trypanosoma brucei''. Humans are infected by two types, ''Trypanosoma brucei gambiense'' (TbG) and ''Trypanosoma brucei rhodesiense'' (TbR). TbG causes over 92% of reported cases. Both are usually transmitted by the bite of an infected tsetse fly and are most common in rural areas. Initially, the first stage of the disease is characterized by fevers, headaches, itchiness, and joint pains, beginning one to three weeks after the bite. Weeks to months later, the second stage begins with confusion, poor coordination, numbness, and trouble sleeping. Diagnosis involves detecting the parasite in a blood smear or lymph node fluid. A lumbar puncture is often needed to tell the difference between first- and second-stage disease. Prevention of severe disease in ...
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