|
Flybase
FlyBase is an online bioinformatics database and the primary repository of genetic and molecular data for the insect family Drosophilidae. For the most extensively studied species and model organism, ''Drosophila melanogaster'', a wide range of data are presented in different formats. Information in FlyBase originates from a variety of sources ranging from large-scale genome projects to the primary research literature. These data types include mutant phenotypes; molecular characterization of mutant alleles; and other deviations, cytological maps, wild-type expression patterns, anatomical images, transgenic constructs and insertions, sequence-level gene models, and molecular classification of gene product functions. Query tools allow navigation of FlyBase through DNA or protein sequence, by gene or mutant name, or through terms from the several ontologies used to capture functional, phenotypic, and anatomical data. The database offers several different query tools in order to provid ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Drosophila Melanogaster
''Drosophila melanogaster'' is a species of fly (an insect of the Order (biology), order Diptera) in the family Drosophilidae. The species is often referred to as the fruit fly or lesser fruit fly, or less commonly the "vinegar fly", "pomace fly", or "banana fly". In the wild, ''D. melanogaster'' are attracted to rotting fruit and fermenting beverages, and are often found in orchards, kitchens and pubs. Starting with Charles W. Woodworth's 1901 proposal of the use of this species as a model organism, ''D. melanogaster'' continues to be widely used for biological research in genetics, physiology, microbial pathogenesis, and Life history theory, life history evolution. ''D. melanogaster'' was the first animal to be Fruit flies in space, launched into space in 1947. As of 2017, six Nobel Prizes have been awarded to drosophilists for their work using the insect. ''Drosophila melanogaster'' is typically used in research owing to its rapid life cycle, relatively simple genetics with on ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Drosophila Databases
Research on the model organism ''Drosophila melanogaster'' has been facilitated by the development of a number of online databases for the storage and curation of certain biological data. DroID The Drosophila Interactions Database (DroID) is an online database of ''Drosophila'' gene and protein interactions. It was developed by Russell L. Finley's laboratory at Wayne State University School of Medicine in 2008 and has been funded by the National Human Genome Research Institute, National Institutes of Health's National Center for Research Resources, Michigan Proteome Consortium, and Wayne State University. FlyBase FlyBase is the major online database for scientists who work on ''Drosophila''. It contains genome data for various ''Drosophila'' species, gene annotations, gene function predictions, and a variety of experimental data that can be overlaid over the genome. FlyBase was developed in 1992 by Michael Ashburner at the University of Cambridge, but is now run by a consortiu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Drosophila Melanogaster Genetics
''Drosophila'' (), from Ancient Greek δρόσος (''drósos''), meaning "dew", and φίλος (''phílos''), meaning "loving", is a genus of fly, belonging to the family Drosophilidae, whose members are often called "small fruit flies" or pomace flies, vinegar flies, or wine flies, a reference to the characteristic of many species to linger around overripe or rotting fruit. They should not be confused with the Tephritidae, a related family, which are also called fruit flies (sometimes referred to as "true fruit flies"); tephritids feed primarily on unripe or ripe fruit, with many species being regarded as destructive agricultural pests, especially the Mediterranean fruit fly. One species of ''Drosophila'' in particular, ''Drosophila melanogaster'', has been heavily used in research in genetics and is a common model organism in developmental biology. The terms "fruit fly" and "''Drosophila''" are often used synonymously with ''D. melanogaster'' in modern biological literature. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Model Organism Databases
Model organism databases (MODs) are biological databases, or knowledgebases, dedicated to the provision of in-depth biological data for intensively studied model organisms. MODs allow researchers to easily find background information on large sets of genes, efficiently plan experiments, integrate their data with existing knowledge, and formulate new hypotheses . They allow users to analyse results and interpret datasets, and the data they generate are increasingly used to describe less well studied species. Where possible, MODs share common approaches to collect and represent biological information. For example, all MODs use the Gene Ontology (GO) to describe functions, processes and cellular locations of specific gene products. Projects also exist to enable software sharing for curation, visualization and querying between different MODs. Organismal diversity and varying user requirements however mean that MODs are often required to customize capture, display, and provision of dat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Generic Model Organism Database
The Generic Model Organism Database (GMOD) project provides biological research communities with a toolkit of open-source software components for visualizing, annotating, managing, and storing biological data. The GMOD project is funded by the United States National Institutes of Health, National Science Foundation and the USDA Agricultural Research Service. History The GMOD project was started in the early 2000s as a collaboration between several model organism databases (MODs) who shared a need to create similar software tools for processing data from sequencing projects. MODs, or organism-specific databases, describe genome and other information about important experimental organisms in the life sciences and capture the large volumes of data and information being generated by modern biology. Rather than each group designing their own software, four major MODs--FlyBase, Saccharomyces Genome Database, Mouse Genome Database, and at or run off a Chado schema database. Chado dat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Xenbase
Xenbase is a Model Organism Database (MOD), providing informatics resources, as well as genomic and biological data on Xenopus frogs.M. Fisher et al. (2023Xenbase: key features and resources of the Xenopus model organism knowledgebase Genetics, Volume 224, Issue 1, May 2023, iyad018, Xenbase has been available since 1999, and covers both X. laevis and X. tropicalis Xenopus varieties. As of 2013 all of its services are running on virtual machines in a private cloud environment, making it one of the first MODs to do so.K. Karimi and P.D. Vize (2014)The Virtual Xenbase: transitioning an online bioinformatics resource to a private cloud Database, doi: 10.1093/database/bau108 Other than hosting genomics data and tools, Xenbase supports the Xenopus research community though profiles for researchers and laboratories, and job and events postings. Xenbase's Software and Hardware Platform Xenbase runs in a cloud environment. Its virtual machines are running in a VMware vSphere environm ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bioinformatics
Bioinformatics () is an interdisciplinary field of science that develops methods and Bioinformatics software, software tools for understanding biological data, especially when the data sets are large and complex. Bioinformatics uses biology, chemistry, physics, computer science, data science, computer programming, information engineering, mathematics and statistics to analyze and interpret biological data. The process of analyzing and interpreting data can sometimes be referred to as computational biology, however this distinction between the two terms is often disputed. To some, the term ''computational biology'' refers to building and using models of biological systems. Computational, statistical, and computer programming techniques have been used for In silico, computer simulation analyses of biological queries. They include reused specific analysis "pipelines", particularly in the field of genomics, such as by the identification of genes and single nucleotide polymorphis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Methods In Molecular Biology
''Methods in Molecular Biology'' is a book series published by Humana Press (an imprint of Springer Science+Business Media) that covers molecular biology research methods and protocols. The book series was introduced by series editor John M. Walker in 1983 and provides step-by-step instructions for carrying out experiments in a research Research is creative and systematic work undertaken to increase the stock of knowledge. It involves the collection, organization, and analysis of evidence to increase understanding of a topic, characterized by a particular attentiveness to ... lab. As of January 2020, more than 2000 volumes (2737 as of 15-August-2023) had been published in the series. The protocols are also available online in SpringerLink, and were previously in '' Springer Protocols''. Each protocol opens with an introductory overview and a list of the materials and reagents needed to complete the experiment. Every protocol is followed by a detailed procedure that is su ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
WormBase
WormBase is an online biological database about the biology and genome of the nematode model organism ''Caenorhabditis elegans'' and contains information about other related nematodes. WormBase is used by the ''C. elegans'' research community both as an information resource and as a place to publish and distribute their results. The database is regularly updated with new versions being released every two months. WormBase is one of the organizations participating in the Generic Model Organism Database (GMOD) project. It is also part of the Alliance of Genome Resources. Contents WormBase comprises the following main data sets: *The annotated genomes of ''Caenorhabditis elegans'', ''Caenorhabditis briggsae'', ''Caenorhabditis remanei'', ''Caenorhabditis brenneri'', ''Caenorhabditis angaria'', ''Pristionchus pacificus'', ''Haemonchus contortus'', ''Meloidogyne hapla'', ''Meloidogyne incognita'', ''Brugia malayi'' and ''Onchocerca volvulus''; *Hand-curated annotations describing the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Citrus Tristeza Virus
''Citrus'' is a genus of flowering trees and shrubs in the family Rutaceae. Plants in the genus produce citrus fruits, including important crops such as oranges, mandarins, lemons, grapefruits, pomelos, and limes. ''Citrus'' is native to South Asia, East Asia, Southeast Asia, Melanesia, and Australia. Indigenous people in these areas have used and domesticated various species since ancient times. Its cultivation first spread into Micronesia and Polynesia through the Austronesian expansion (–1500 BCE). Later, it was spread to the Middle East and the Mediterranean () via the incense trade route, and from Europe to the Americas. Renowned for their highly fragrant aromas and complex flavor, citrus are among the most popular fruits in cultivation. With a propensity to hybridize between species, making their taxonomy complicated, there are numerous varieties encompassing a wide range of appearance and fruit flavors. Evolution Evolutionary history The large citrus fruit o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Toxoptera Citricida
''Toxoptera citricida'' ( syn. ''Toxoptera citricidus'') is a species of aphid known by the common names brown citrus aphid, black citrus aphid, and oriental citrus aphid. It is a pest of citrus and vector for the pathogenic plant virus citrus tristeza virus. The aphid spread the virus through citrus groves in Brazil Brazil, officially the Federative Republic of Brazil, is the largest country in South America. It is the world's List of countries and dependencies by area, fifth-largest country by area and the List of countries and dependencies by population ... and Venezuela in the 1970s, leading to the near destruction of the citrus industry there. This aphid was first discovered in Florida in 1995. The adult aphid is shiny black and wingless (aptera) or winged (alate or alatoid), and the Nymph (biology), nymph is dark reddish brown. The aphid feeds on new buds and leaves. The virus is transmitted when the aphid introduces it into the phloem of the plant. In most parts o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
