Research on the

model organism A model organism is a non-human species that is extensively studied to understand particular biological phenomena, with the expectation that discoveries made in the model organism will provide insight into the workings of other organisms. Mo ...

Drosophila melanogaster ''Drosophila melanogaster'' is a species of fly (an insect of the Order (biology), order Diptera) in the family Drosophilidae. The species is often referred to as the fruit fly or lesser fruit fly, or less commonly the "vinegar fly", "pomace fly" ...

'' has been facilitated by the development of a number of online databases for the storage and curation of certain biological data.

DroID

The Drosophila Interactions Database (DroID) is an online database of ''Drosophila'' gene and protein interactions. It was developed by Russell L. Finley's laboratory at

Wayne State University School of Medicine The Wayne State University School of Medicine (WSUSOM) is the medical school of Wayne State University, a public university, public research university in Detroit, Detroit, Michigan. It enrolls more than 1,500 students in undergraduate medical ed ...

in 2008 and has been funded by the

National Human Genome Research Institute The National Human Genome Research Institute (NHGRI) is an institute of the National Institutes of Health, located in Bethesda, Maryland. NHGRI began as the Office of Human Genome Research in The Office of the Director in 1988. This Office transi ...

, National Institutes of Health's National Center for Research Resources, Michigan Proteome Consortium, and Wayne State University.

FlyBase

FlyBase FlyBase is an online bioinformatics database and the primary repository of genetic and molecular data for the insect family Drosophilidae. For the most extensively studied species and model organism, ''Drosophila melanogaster'', a wide range of da ...

is the major online database for scientists who work on ''Drosophila''. It contains genome data for various ''Drosophila'' species, gene annotations, gene function predictions, and a variety of experimental data that can be overlaid over the genome. FlyBase was developed in 1992 by

Michael Ashburner Michael Ashburner (23 May 1942 – 7 July 2023) was an English biologist and Professor in the Department of Genetics at University of Cambridge. He also served as joint-head and co-founder of the European Bioinformatics Institute (EBI) of the ...

at the

University of Cambridge The University of Cambridge is a Public university, public collegiate university, collegiate research university in Cambridge, England. Founded in 1209, the University of Cambridge is the List of oldest universities in continuous operation, wo ...

, but is now run by a consortium of groups from

Harvard University Harvard University is a Private university, private Ivy League research university in Cambridge, Massachusetts, United States. Founded in 1636 and named for its first benefactor, the History of the Puritans in North America, Puritan clergyma ...

, University of Cambridge,

Indiana University Indiana University (IU) is a state university system, system of Public university, public universities in the U.S. state of Indiana. The system has two core campuses, five regional campuses, and two regional centers under the administration o ...

, and the

University of New Mexico The University of New Mexico (UNM; ) is a public research university in Albuquerque, New Mexico, United States. Founded in 1889 by the New Mexico Territorial Legislature, it is the state's second oldest university, a flagship university in th ...

FlyFactorSurvey

FlyFactorSurvey is a database of ''Drosophila''

transcription factor In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription (genetics), transcription of genetics, genetic information from DNA to messenger RNA, by binding t ...

s determined using the bacterial one-hybrid system. It was developed by the laboratories of Michael H. Brodsky and Scot Wolfe at the

University of Massachusetts Medical School The UMass Chan Medical School is a public medical school in Worcester, Massachusetts. It is part of the University of Massachusetts system. It consists of three schools: the T.H. Chan School of Medicine, the Morningside Graduate School of Biom ...

in 2011, and was funded by the

FlyMine

FlyMine is a database of transcription, protein expression, and other protein data for ''Drosophila'' and ''

Anopheles ''Anopheles'' () is a genus of mosquito first described by the German entomologist Johann Wilhelm Meigen, J. W. Meigen in 1818, and are known as nail mosquitoes and marsh mosquitoes. Many such mosquitoes are Disease vector, vectors of the paras ...

'' species. It was originally developed by Gos Micklem's group at

Cambridge University The University of Cambridge is a Public university, public collegiate university, collegiate research university in Cambridge, England. Founded in 1209, the University of Cambridge is the List of oldest universities in continuous operation, wo ...

in 2007. FlyMine is funded primarily by

Wellcome Trust The Wellcome Trust is a charitable foundation focused on health research based in London, United Kingdom. It was established in 1936 with legacies from the pharmaceutical magnate Henry Wellcome (founder of Burroughs Wellcome, one of the predec ...

, with elements of the database supported by the

and the

Biotechnology and Biological Sciences Research Council Biotechnology and Biological Sciences Research Council (BBSRC), part of UK Research and Innovation, is a non-departmental public body (NDPB), and is the largest UK public funder of non-medical bioscience. It predominantly funds science, scient ...

OnTheFly

OnTheFly is a database of ''D. melanogaster'' transcription factors and the DNA sequences they bind. It was developed by the laboratory of Barry Honig at

Columbia University Medical School The Columbia University College of Physicians and Surgeons (officially known as Columbia University Roy and Diana Vagelos College of Physicians and Surgeons) is the medical school of Columbia University, located at the Columbia University Irving ...

in 2013.

REDfly

REDfly (Regulatory Element Database) is a database of ''Drosophila''

cis-regulatory element ''Cis''-regulatory elements (CREs) or ''cis''-regulatory modules (CRMs) are regions of non-coding DNA which regulate the transcription of neighboring genes. CREs are vital components of genetic regulatory networks, which in turn control morpho ...

s. It was developed by the laboratory of Marc S. Halfon at the

University of Buffalo The State University of New York at Buffalo (commonly referred to as UB, University at Buffalo, and sometimes SUNY Buffalo) is a public university, public research university in Buffalo, New York, Buffalo and Amherst, New York, United States. ...

in 2006, and has been funded by the

National Science Foundation The U.S. National Science Foundation (NSF) is an Independent agencies of the United States government#Examples of independent agencies, independent agency of the Federal government of the United States, United States federal government that su ...

and the

National Institute of General Medical Sciences The National Institute of General Medical Sciences (NIGMS) is one of the National Institutes of Health, National Institutes of Health (NIH), the principal medical research agency of the United States Federal government of the United States, Fe ...

References

{{DEFAULTSORT:Drosophila databases

Databases In computing, a database is an organized collection of data or a type of data store based on the use of a database management system (DBMS), the software that interacts with end users, applications, and the database itself to capture and ana ...

Database-related lists